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General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
KLK13 26085 kallikrein-related peptidase 13  19KLK-L4 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
19367279   2009Cell line : -

Source : Oncologic Hospital of Athens �Saint Savvas.

Sample Type : CRC tumor

No. of Sample : 122

Stage : -

Immunofluorometric ELISA measurement of kallikreinsUp-regulation--


Gene Details



NC_000019.9 (51559021..51568367, complement)

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Gene Type protein coding
Gene Family Kallikreins
Description Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Expression of this gene is regulated by steroid hormones and may be useful as a marker for breast cancer. An additional transcript variant has been identified, but its full length sequence has not been determined. [provided by RefSeq, Jul 2008]  
Chromosome 19
Location 19q13.33
Start 51559021  
End 51568367  
Strand -  
Gene Sequence

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Length 9347  
OMIM ID 605505   
HGNC ID HGNC:6361   
Unigene ID Hs.165296   
Ensembl ID -   
PharmGKB ID PA30150   

mRNA Information


mRNA ID ?NM_015596.1
Exon  
mRNA Sequence

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Length  



CDS Information


   
Location
CDS Sequence

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CCDS ID CCDS12822.1



Protein Information


      
Protein IDNP_056411.1
Protein Namekallikrein-related peptidase 13
Molecular Wt. (Da)0
Protein Sequence

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Length 277  
Uniprot IDQ9BUR4
Ensembl Protein ID ENSP00000324203  



Post-translational Modification Information (Source : HPRD)


No matching records could be found.

Enzyme Information


No matching records could be found.

PPi Information


(Click to view network : Source STRING)      View   

               
Interactant Gene ID (Source: HPRD) Gene Symbol HPRD ID Ref Seq ID Technique References
5345SERPINF22029NP_000925.2in vitro14687906   


Pathway Information


No matching records could be found.

Structure Information


No matching records could be found.

Domain Information




ID Location Description
cd0019038-261  Tryp_SPc
cl2158438-261  Tryp_SPc superfamily
smart0002038-258  Tryp_SPc
pfam0008938-258  Trypsin
COG564010-274  COG5640
pfam0934248-152  DUF1986


Ontology Information


   
HPRD ID17607
Molecular ClassSerine protease
Molecular FunctionOxidoreductase activity (GO:0016491)
Biological ProcessCell growth and/or maintenance (GO:0008151)  



SNP Information


View SNP Geneview Report   

Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO