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General Information
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Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 19367279 | 2009 | Cell line : - Source : Oncologic Hospital of Athens �Saint Savvas. Sample Type : CRC tumor No. of Sample : 122 Stage : - | Immunofluorometric ELISA measurement of kallikreins | Up-regulation | - | - |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | Kallikreins |
| Description | Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Expression of this gene is regulated by steroid hormones and may be useful as a marker for breast cancer. An additional transcript variant has been identified, but its full length sequence has not been determined. [provided by RefSeq, Jul 2008] | Chromosome | 19 |
| Location | 19q13.33 |
| Start | 51559021 |
| End | 51568367 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 9347 |
| OMIM ID | 605505 |
| HGNC ID | HGNC:6361 |
| Unigene ID | Hs.165296 |
| Ensembl ID | - |
| PharmGKB ID | PA30150 |
Protein Information
| Protein ID | NP_056411.1 |
|---|---|
| Protein Name | kallikrein-related peptidase 13 |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 277 |
| Uniprot ID | Q9BUR4 |
| Ensembl Protein ID | ENSP00000324203 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 5345 | SERPINF2 | 2029 | NP_000925.2 | in vitro | 14687906 |
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd00190 | 38-261 | Tryp_SPc |
| cl21584 | 38-261 | Tryp_SPc superfamily |
| smart00020 | 38-258 | Tryp_SPc |
| pfam00089 | 38-258 | Trypsin |
| COG5640 | 10-274 | COG5640 |
| pfam09342 | 48-152 | DUF1986 |
Ontology Information
| HPRD ID | 17607 |
|---|---|
| Molecular Class | Serine protease |
| Molecular Function | Oxidoreductase activity (GO:0016491) |
| Biological Process | Cell growth and/or maintenance (GO:0008151) |
Drug Information
No matching records could be found.