Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| GTF2E1 | 2960 | General transcription factor IIE, polypeptide 1, alpha 56kDa  | 3 | FE; TF2E1; TFIIE-A  |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 22968445    | 2012 | Cell line : - Source : Department of Pathology of Wrocaw Medical University. Sample Type : - No. of Sample : - Stage : - | Laser capture microdissection,FFPE-FASP,SAX fractionation, LC-MSMS,Label-freequantitation | Up-regulation | 4.4 | - |
Gene Details

| Gene Type | protein coding |
|---|---|
| Gene Family | General transcription factors |
| Description | -   |
| Chromosome | 3 |
| Location | 3q21-q24 |
| Start | 120742711   |
| End | 120783070   |
| Strand | +   |
| Gene Sequence |    Download   Select all |
| Length | 40360   |
| OMIM ID | 189962    |
| HGNC ID | HGNC:4650    |
| Unigene ID | Hs.445272     |
| Ensembl ID | ENSG00000153767    |
| PharmGKB ID | -    |
mRNA Information
| mRNA ID | NM_005513.2 |
|---|---|
| Exon | join(1..84,7813..8290,28018..28219,33713..33954, 38333..40359)   | mRNA Sequence |    Download   Select all |
| Length | 3033   |
CDS Information
| Location | join(7843..8290,28018..28219,33713..33954,38333..38760) |
|---|---|
| CDS Sequence |    Download   Select all |
| CCDS ID | - |    
Protein Information
| Protein ID | NP_005504.2 |
|---|---|
| Protein Name | General transcription factor IIE, polypeptide 1, alpha 56kDa |
| Molecular Wt. (Da) | 49321 |
| Protein Sequence |    Download   Select all |
| Length | 439   |
| Uniprot ID | Q13886 |    
| Ensembl Protein ID | ENSP00000366330   |    
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| S | Phosphorylation | 268 |
| K | Acetylation | 67 |
| T | Phosphorylation | 98 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING)      View   
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 2071 |    ERCC3 |    593 |    NP_000113.1 |    in vitro;in vivo |    81   524   907   926   747    |
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Basal transcription factors |    hsa03022 |    
| Epstein-Barr virus infection |    hsa05169 |    
| Viral carcinogenesis |    hsa05203 |    
Structure Information
| PDB ID | 1VD4 |
|---|---|
| Resolution | - |
| Method | solution NMR |
| Chains | A   |
| Molecule | Transcription initiation factor IIE, alpha subunit   |
| Model | View |
Domain Information
| ID | Location | Description |
|---|---|---|
| pfam02002 | 16-123  | TFIIE_alpha |
| cl21459 | 16-123  | HTH superfamily |
| pfam11521 | 367-439  | TFIIE-A_C-term |
| cl13037 | 367-439  | TFIIE-A_C-term superfamily |
| pfam08271 | 127-174  | TF_Zn_Ribbon |
| cl07036 | 127-174  | TF_Zn_Ribbon superfamily |
| smart00531 | 28-175  | TFIIE |
| COG1675 | 14-187  | TFA1 |
Ontology Information
| HPRD ID | 4211 |    
|---|---|
| Molecular Class | Transcription factor |
| Molecular Function | Transcription factor activity (GO:0003700) |
| Biological Process | Regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0019219)   |
Drug Information
No matching records could be found.
External Links
| ArrayExpress | GO |    
|---|---|
| ICGC | GO |    
| Cancer3D | GO |    
| COSMIC | GO |    
| NCG | GO |    
| TSGene | GO |    
| Tumor Gene Family of Databases | GO |    
| CCDB | GO |    
| G2SBC | GO |    
| Osteosarcoma Database | GO |    
| RCDB | GO |    
