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General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
GTF2E1 2960 General transcription factor IIE, polypeptide 1, alpha 56kDa  3FE; TF2E1; TFIIE-A 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
22968445   2012Cell line : -

Source : Department of Pathology of Wrocaw Medical University.

Sample Type : -

No. of Sample : -

Stage : -

Laser capture microdissection,FFPE-FASP,SAX fractionation, LC-MSMS,Label-freequantitationUp-regulation4.4-


Gene Details



Chromosome: 3; NC_000003.11 (120461558..120501916)

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Gene Type protein coding
Gene Family General transcription factors
Description -  
Chromosome 3
Location 3q21-q24
Start 120742711  
End 120783070  
Strand +  
Gene Sequence

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Length 40360  
OMIM ID 189962   
HGNC ID HGNC:4650   
Unigene ID Hs.445272    
Ensembl ID ENSG00000153767   
PharmGKB ID -   

mRNA Information


mRNA ID NM_005513.2
Exon join(1..84,7813..8290,28018..28219,33713..33954, 38333..40359)  
mRNA Sequence

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Length 3033  



CDS Information


   
Location join(7843..8290,28018..28219,33713..33954,38333..38760)
CDS Sequence

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CCDS ID -



Protein Information


      
Protein IDNP_005504.2
Protein NameGeneral transcription factor IIE, polypeptide 1, alpha 56kDa
Molecular Wt. (Da)49321
Protein Sequence

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Length 439  
Uniprot IDQ13886
Ensembl Protein ID ENSP00000366330  



Post-translational Modification Information (Source : HPRD)


Residue Type site
SPhosphorylation268
KAcetylation67
TPhosphorylation98

Enzyme Information


No matching records could be found.

PPi Information


(Click to view network : Source STRING)      View   

               
Interactant Gene ID (Source: HPRD) Gene Symbol HPRD ID Ref Seq ID Technique References
2071ERCC3593NP_000113.1in vitro;in vivo81   524   907   926   747   


Pathway Information


                  
Pathway Name Pathway ID
Basal transcription factors hsa03022
Epstein-Barr virus infection hsa05169
Viral carcinogenesis hsa05203


Structure Information


PDB ID1VD4
Resolution-
Methodsolution NMR
Chains A  
Molecule Transcription initiation factor IIE, alpha subunit  
Model View



Domain Information




ID Location Description
pfam0200216-123  TFIIE_alpha
cl2145916-123  HTH superfamily
pfam11521367-439  TFIIE-A_C-term
cl13037367-439  TFIIE-A_C-term superfamily
pfam08271127-174  TF_Zn_Ribbon
cl07036127-174  TF_Zn_Ribbon superfamily
smart0053128-175  TFIIE
COG167514-187  TFA1


Ontology Information


   
HPRD ID4211
Molecular ClassTranscription factor
Molecular FunctionTranscription factor activity (GO:0003700)
Biological ProcessRegulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0019219)  



SNP Information


View SNP Geneview Report   

Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO