Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| MAP3K5 | 4217 | mitogen-activated protein kinase kinase kinase 5 | 6 | MAPKKK5, ASK1 |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 23027623 | 2012 | Cell line : - Source : Twin Cities Metropolitan Area or a seven-county area of Utah or enrolled in the Kaiser Permanente Medical Care Program of Northern California (KPMCP). Sample Type : Population-based case-control No. of Sample : Colon 1555 cases, 1956 controls; rectal 754 cases, 959 controls Stage : - | TagSNP selection and genotyping | Polymorhpism | - | - |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | Mitogen-activated protein kinase cascade / Kinase kinase kinases |
| Description | Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MAPKKK5 contains 1,374 amino acids with all 11 kinase subdomains. Northern blot analysis shows that MAPKKK5 transcript is abundantly expressed in human heart and pancreas. The MAPKKK5 protein phosphorylates and activates MKK4 (aliases SERK1, MAPKK4) in vitro, and activates c-Jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK) during transient expression in COS and 293 cells; MAPKKK5 does not activate MAPK/ERK. [provided by RefSeq, Jul 2008] |
| Chromosome | 6 |
| Location | 6q22.33 |
| Start | 136878184 |
| End | 137113656 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 235473 |
| OMIM ID | 602448 |
| HGNC ID | HGNC:6857 |
| Unigene ID | Hs.186486 |
| Ensembl ID | ENSG00000197442 |
| PharmGKB ID | PA30601 |
mRNA Information
| mRNA ID | XM_011535838.1 |
|---|---|
| Exon | join(1..1342,72463..72602,87919..87942,94370..94563, 95665..95833,96995..97101,98742..98912,123657..123769, 133674..133833,136592..136745,141961..142068, 150483..150532,153414..153509,155646..155727, 170071..170204,178766..178893,179796..179932, 181665..181770,187686..187843,191073..191250, 192010..192030,200435..200615,200711..200879, 209312..209497,212646..212751,225178..225421, 230437..230549,231407..231519,234176..234252, 235234..236006) | mRNA Sequence | Download Select all |
| Length | 5734 |
Protein Information
| Protein ID | XP_011534140.1 |
|---|---|
| Protein Name | mitogen-activated protein kinase kinase kinase 5 |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 1375 |
| Uniprot ID | P16035 |
| Ensembl Protein ID | ENSP00000262768 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| T | Phosphorylation | 842 |
| S | Phosphorylation | 966 |
| T | Dephosphorylation | 842 |
| T | Phosphorylation | 838 |
| S | Phosphorylation | 83 |
| S | Phosphorylation | 1029 |
| S | Phosphorylation | 1033 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 409 | ARRB2 | 147 | NP_004304.1 | in vivo | 11356842 |
| 993 | CDC25A | 305 | NP_001780.2 | in vitro;in vivo;yeast 2-hybrid | 11416155 |
| 2745 | GLRX | 2707 | NP_002055.1 | in vitro | 12244106 |
| 2944 | GSTM1 | 707 | NP_000552.2 | in vitro;in vivo | 1 127 828 912 077 130 |
| 3303 | HSPA1A | 774 | NP_005336.3 | in vitro;in vivo | 12391142 |
| 5610 | EIF2AK2 | 1468 | NP_002750.1 | in vitro;in vivo | 12473108 |
| 5894 | RAF1 | 1265 | NP_002871.1 | in vitro;in vivo | 11427728 |
| 7139 | TNNT2 | 1844 | NP_000355.2 | in vivo | 12819028 |
| 7164 | TPD52L1 | 7236 | NP_003278.1 | in vivo | 14761963 |
| 7186 | TRAF2 | 3538 | NP_066961.2 | in vitro;in vivo | 977 497 710 523 862 |
| 7188 | TRAF5 | 3834 | NP_004610.1 | in vitro;in vivo | 10523862 |
| 7189 | TRAF6 | 3833 | NP_665802.1 | in vitro;in vivo | 10523862 |
| 7295 | TXN | 1761 | NP_003320.2 | in vitro;in vivo;yeast 2-hybrid | 120 890 639 564 042 |
| 7533 | YWHAH | 215 | NP_003396.1 | yeast 2-hybrid | 15023544 |
| 7534 | YWHAZ | 3183 | NP_003397.1 | in vitro;in vivo | 1 041 190 611 336 670 |
| 10016 | PDCD6 | 3035 | NP_037364.1 | in vitro | 12372597 |
| 10971 | YWHAQ | 886 | NP_006817.1 | yeast 2-hybrid | 15023544 |
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Amyotrophic lateral sclerosis (ALS) | hsa05014 |
| MAPK signaling pathway | hsa04010 |
| Neurotrophin signaling pathway | hsa04722 |
| Non-alcoholic fatty liver disease (NAFLD) | hsa04932 |
| Protein processing in endoplasmic reticulum | hsa04141 |
| Sphingolipid signaling pathway | hsa04071 |
| TNF signaling pathway | hsa04668 |
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd06624 | 671-938 | STKc_ASK |
| cl21453 | 671-938 | PKc_like superfamily |
| pfam13281 | 165-545 | DUF4071 |
| cl19991 | 165-545 | DUF4071 superfamily |
| cd06606 | 685-938 | STKc_MAPKKK |
| cd05122 | 682-938 | PKc_STE |
| cd06632 | 686-938 | STKc_MEKK1_plant |
| cd06626 | 687-938 | STKc_MEKK4 |
| cd06627 | 686-933 | STKc_Cdc7_like |
| cd06625 | 685-937 | STKc_MEKK3_like |
| cd06629 | 686-938 | STKc_Bck1_like |
| cd06631 | 685-938 | STKc_YSK4 |
| cd06628 | 685-938 | STKc_Byr2_like |
| cd06612 | 672-938 | STKc_MST1_2 |
| cd08215 | 685-938 | STKc_Nek |
| cd06630 | 685-934 | STKc_MEKK1 |
| cd06623 | 685-943 | PKc_MAPKK_plant_like |
| cd05117 | 685-937 | STKc_CAMK |
| cd00180 | 686-933 | PKc |
| cd06614 | 682-939 | STKc_PAK |
| cd14007 | 686-939 | STKc_Aurora |
| cd06609 | 685-944 | STKc_MST3_like |
| cd13999 | 686-926 | STKc_MAP3K-like |
| cd14014 | 685-937 | STKc_PknB_like |
| cd05123 | 686-931 | STKc_AGC |
| cd06613 | 686-937 | STKc_MAP4K3_like |
| cd14003 | 685-937 | STKc_AMPK-like |
| cd14008 | 686-938 | STKc_LKB1_CaMKK |
| cd06652 | 685-937 | STKc_MEKK2 |
| cd06653 | 685-937 | STKc_MEKK3_like_u1 |
| cd06610 | 674-933 | STKc_OSR1_SPAK |
| cd14099 | 686-938 | STKc_PLK |
| cd06651 | 685-940 | STKc_MEKK3 |
| cd06917 | 685-943 | STKc_NAK1_like |
| cd05118 | 685-938 | STKc_CMGC |
| cd13983 | 684-938 | STKc_WNK |
| cd06608 | 685-938 | STKc_myosinIII_N_like |
| cd06605 | 685-939 | PKc_MAPKK |
| cd08217 | 685-938 | STKc_Nek2 |
| cd06621 | 686-945 | PKc_Pek1_like |
| cd06611 | 686-948 | STKc_SLK_like |
| cd07829 | 675-938 | STKc_CDK_like |
| cd08220 | 685-933 | STKc_Nek8 |
| cd06647 | 686-939 | STKc_PAK_I |
| cd08530 | 685-933 | STKc_CNK2-like |
| cd05581 | 685-926 | STKc_PDK1 |
| cd08225 | 685-938 | STKc_Nek5 |
| cd06648 | 681-939 | STKc_PAK_II |
| cd05572 | 686-926 | STKc_cGK |
| cd05579 | 688-930 | STKc_MAST_like |
| cd14080 | 686-933 | STKc_TSSK-like |
| cd14098 | 685-933 | STKc_Rad53_Cds1 |
| cd14137 | 685-937 | STKc_GSK3 |
| cd08529 | 686-933 | STKc_FA2-like |
| cd14009 | 686-926 | STKc_ATG1_ULK_like |
| cd05580 | 685-926 | STKc_PKA_like |
| cd08218 | 686-938 | STKc_Nek1 |
| cd06643 | 686-945 | STKc_SLK |
| cd06654 | 686-953 | STKc_PAK1 |
| cd08224 | 686-934 | STKc_Nek6_7 |
| cd14189 | 685-938 | STKc_PLK3 |
| cd14188 | 685-938 | STKc_PLK2 |
| cd06656 | 686-953 | STKc_PAK3 |
| cd00192 | 685-933 | PTKc |
| cd07840 | 686-937 | STKc_CDK9_like |
| cd06655 | 686-964 | STKc_PAK2 |
| cd14084 | 685-933 | STKc_Chk2 |
| cd06620 | 686-946 | PKc_Byr1_like |
| cd06622 | 686-939 | PKc_PBS2_like |
| cd06640 | 686-944 | STKc_MST4 |
| cd14663 | 685-927 | STKc_SnRK3 |
| cd14006 | 686-933 | STKc_MLCK-like |
| cd07833 | 685-933 | STKc_CDKL |
| cd13996 | 685-933 | STKc_EIF2AK |
| cd05611 | 688-930 | STKc_Rim15_like |
| cd13994 | 686-938 | STKc_HAL4_like |
| cd06641 | 686-944 | STKc_MST3 |
| cd14002 | 685-938 | STKc_STK36 |
| cd06638 | 686-938 | STKc_myosinIIIA_N |
| cd06644 | 686-944 | STKc_STK10 |
| cd14131 | 686-938 | PKc_Mps1 |
| cd08222 | 686-938 | STKc_Nek11 |
| cd07834 | 685-939 | STKc_MAPK |
| cd06607 | 686-938 | STKc_TAO |
| cd06642 | 686-944 | STKc_STK25 |
| cd06646 | 672-938 | STKc_MAP4K5 |
| cd13993 | 685-933 | STKc_Pat1_like |
| cd08528 | 686-926 | STKc_Nek10 |
| cd06645 | 686-938 | STKc_MAP4K3 |
| cd14166 | 685-926 | STKc_CaMKI_gamma |
| cd05612 | 686-926 | STKc_PRKX_like |
| cd08228 | 686-926 | STKc_Nek6 |
| cd14167 | 683-926 | STKc_CaMKI_alpha |
| cd08219 | 685-933 | STKc_Nek3 |
| cd07832 | 686-881 | STKc_CCRK |
| cd14069 | 686-938 | STKc_Chk1 |
| cd06659 | 682-938 | STKc_PAK6 |
| cd14081 | 686-926 | STKc_BRSK1_2 |
| cd14059 | 686-926 | STKc_MAP3K12_13 |
| cd07841 | 686-939 | STKc_CDK7 |
| cd14187 | 686-938 | STKc_PLK1 |
| cd08223 | 685-938 | STKc_Nek4 |
| cd06639 | 686-939 | STKc_myosinIIIB_N |
| cd14086 | 674-933 | STKc_CaMKII |
| cd06637 | 685-951 | STKc_TNIK |
| cd05583 | 752-936 | STKc_MSK_N |
| cd06617 | 686-954 | PKc_MKK3_6 |
| cd14120 | 686-926 | STKc_ULK1_2-like |
| cd14097 | 686-933 | STKc_STK33 |
| cd06658 | 686-941 | STKc_PAK5 |
| cd06636 | 685-892 | STKc_MAP4K4_6_N |
| cd13995 | 688-938 | STKc_MAP3K8 |
| cd13997 | 686-933 | PKc_Wee1_like |
| cd13979 | 684-930 | STKc_Mos |
| cd14119 | 686-927 | STKc_LKB1 |
| cd14083 | 685-926 | STKc_CaMKI |
| cd07838 | 686-938 | STKc_CDK4_6_like |
| cd14012 | 720-937 | PK_eIF2AK_GCN2_rpt1 |
| cd06615 | 684-943 | PKc_MEK |
| cd14094 | 685-939 | STKc_CASK |
| cd06633 | 686-939 | STKc_TAO3 |
| cd13978 | 686-926 | STKc_RIP |
| cd06657 | 684-938 | STKc_PAK4 |
| cd07835 | 686-881 | STKc_CDK1_CdkB_like |
| cd14209 | 679-882 | STKc_PKA |
| cd07846 | 685-937 | STKc_CDKL2_3 |
| cd07849 | 685-881 | STKc_ERK1_2_like |
| cd05584 | 685-931 | STKc_p70S6K |
| cd14186 | 685-938 | STKc_PLK4 |
| cd14116 | 686-934 | STKc_Aurora-A |
| cd07866 | 674-879 | STKc_BUR1 |
| cd07845 | 686-881 | STKc_CDK10 |
| cd14004 | 685-938 | STKc_PASK |
| cd07836 | 686-881 | STKc_Pho85 |
| cd05570 | 684-926 | STKc_PKC |
| cd07830 | 686-933 | STKc_MAK_like |
| cd14202 | 685-938 | STKc_ULK1 |
| cd14005 | 685-926 | STKc_PIM |
| cd06634 | 686-938 | STKc_TAO2 |
| cd14010 | 677-937 | STKc_ULK4 |
| cd14096 | 686-938 | STKc_RCK1-like |
| cd14118 | 686-926 | STKc_CAMKK |
| cd14210 | 669-938 | PKc_DYRK |
| cd14665 | 686-926 | STKc_SnRK2-3 |
| cd14050 | 685-933 | PKc_Myt1 |
| cd08229 | 686-926 | STKc_Nek7 |
| cd14095 | 685-936 | STKc_DCKL |
| cd07842 | 687-937 | STKc_CDK8_like |
| cd08221 | 685-938 | STKc_Nek9 |
| cd14201 | 674-926 | STKc_ULK2 |
| cd06635 | 686-938 | STKc_TAO1 |
| cd14121 | 686-926 | STKc_ULK3 |
| cd14169 | 686-926 | STKc_CaMKI_beta |
| cd13985 | 683-933 | STKc_GAK_like |
| cd06618 | 686-939 | PKc_MKK7 |
| cd05592 | 685-926 | STKc_nPKC_theta_like |
| cd14185 | 685-933 | STKc_DCKL3 |
| cd05613 | 685-926 | STKc_MSK1_N |
| cd14162 | 685-881 | STKc_TSSK4-like |
| cd07860 | 686-881 | STKc_CDK2_3 |
| cd05578 | 685-926 | STKc_Yank1 |
| cd14061 | 685-935 | STKc_MLK |
| cd14194 | 676-933 | STKc_DAPK1 |
| cd05573 | 685-918 | STKc_ROCK_NDR_like |
| cd14200 | 686-938 | STKc_CaMKK1 |
| cd14091 | 674-933 | STKc_RSK_C |
| cd14093 | 697-938 | STKc_PhKG |
| cd14117 | 686-944 | STKc_Aurora-B_like |
| cd14662 | 686-926 | STKc_SnRK2 |
| cd05616 | 684-926 | STKc_cPKC_beta |
| cd14066 | 686-926 | STKc_IRAK |
| cd14107 | 686-938 | STKc_obscurin_rpt1 |
| cd05587 | 754-926 | STKc_cPKC |
| cd05575 | 685-926 | STKc_SGK |
| cd07854 | 686-881 | STKc_MAPK4_6 |
| cd14133 | 685-938 | PKc_DYRK_like |
| cd05571 | 685-926 | STKc_PKB |
| cd07843 | 689-886 | STKc_CDC2L1 |
| cd13990 | 686-927 | STKc_TLK |
| cd07851 | 686-881 | STKc_p38 |
| cd14148 | 685-926 | STKc_MLK2 |
| cd06650 | 686-941 | PKc_MEK1 |
| cd14101 | 685-939 | STKc_PIM2 |
| cd14070 | 686-938 | STKc_HUNK |
| cd07856 | 686-881 | STKc_Sty1_Hog1 |
| cd05614 | 685-926 | STKc_MSK2_N |
| cd07852 | 686-939 | STKc_MAPK15-like |
| cd14082 | 685-883 | STKc_PKD |
| cd07861 | 686-882 | STKc_CDK1_euk |
| cd05595 | 685-926 | STKc_PKB_beta |
| cd07848 | 685-881 | STKc_CDKL5 |
| cd13991 | 686-932 | STKc_NIK |
| cd14060 | 687-933 | STKc_MLTK |
| cd07847 | 686-933 | STKc_CDKL1_4 |
| cd05589 | 685-926 | STKc_PKN |
| cd14145 | 685-933 | STKc_MLK1 |
| cd07865 | 686-879 | STKc_CDK9 |
| cd07855 | 675-881 | STKc_ERK5 |
| cd05038 | 686-932 | PTKc_Jak_rpt2 |
| cd14103 | 686-933 | STKc_MLCK |
| cd14073 | 675-881 | STKc_NUAK |
| cd06619 | 683-938 | PKc_MKK5 |
| cd14033 | 686-938 | STKc_WNK4 |
| cd06616 | 673-939 | PKc_MKK4 |
| cd07857 | 686-881 | STKc_MPK1 |
| cd14075 | 686-938 | STKc_NIM1 |
| cd05593 | 685-926 | STKc_PKB_gamma |
| cd07880 | 686-881 | STKc_p38gamma |
| cd14090 | 677-933 | STKc_Mnk |
| cd05609 | 689-926 | STKc_MAST |
| cd14079 | 686-938 | STKc_AMPK_alpha |
| cd05615 | 684-926 | STKc_cPKC_alpha |
| cd14077 | 686-927 | STKc_Kin1_2 |
| cd05603 | 685-882 | STKc_SGK2 |
| cd14192 | 685-938 | STKc_MLCK3 |
| cd14181 | 672-938 | STKc_PhKG2 |
| cd07844 | 685-962 | STKc_PCTAIRE_like |
| cd14164 | 686-926 | STKc_TSSK6-like |
| cd05602 | 685-882 | STKc_SGK1 |
| cd14111 | 687-938 | STKc_SPEG_rpt2 |
| cd14165 | 686-938 | STKc_TSSK1_2-like |
| cd05599 | 737-937 | STKc_NDR_like |
| cd14089 | 683-939 | STKc_MAPKAPK |
| cd14074 | 686-938 | STKc_SNRK |
| cd07877 | 686-881 | STKc_p38alpha |
| cd14072 | 686-938 | STKc_MARK |
| cd05621 | 679-882 | STKc_ROCK2 |
| cd05604 | 685-931 | STKc_SGK3 |
| cd07863 | 686-938 | STKc_CDK4 |
| cd14052 | 686-876 | PTKc_Wee1_fungi |
| cd14168 | 685-926 | STKc_CaMKI_delta |
| cd14161 | 671-881 | STKc_NUAK2 |
| cd14199 | 686-926 | STKc_CaMKK2 |
| cd14092 | 676-947 | STKc_MSK_C |
| cd14196 | 686-933 | STKc_DAPK2 |
| cd14062 | 686-926 | STKc_Raf |
| cd08216 | 684-939 | PK_STRAD |
| cd14058 | 686-926 | STKc_TAK1 |
| cd14039 | 686-887 | STKc_IKK_alpha |
| cd05079 | 686-933 | PTKc_Jak1_rpt2 |
| cd14046 | 685-936 | STKc_EIF2AK4_GCN2_rpt2 |
| cd05582 | 685-926 | STKc_RSK_N |
| cd14176 | 675-933 | STKc_RSK2_C |
| cd14037 | 685-926 | STKc_NAK_like |
| cd14109 | 675-939 | PK_Unc-89_rpt1 |
| cd14088 | 694-938 | STKc_CaMK_like |
| cd05577 | 686-926 | STKc_GRK |
| cd14190 | 683-915 | STKc_MLCK2 |
| cd05585 | 685-949 | STKc_YPK1_like |
| cd14105 | 686-933 | STKc_DAPK |
| cd07878 | 686-881 | STKc_p38beta |
| cd14184 | 685-933 | STKc_DCKL2 |
| cd05619 | 685-926 | STKc_nPKC_theta |
| cd14195 | 686-940 | STKc_DAPK3 |
| cd05041 | 686-926 | PTKc_Fes_like |
| cd07871 | 686-881 | STKc_PCTAIRE3 |
| cd05591 | 685-881 | STKc_nPKC_epsilon |
| cd06649 | 678-880 | PKc_MEK2 |
| cd14114 | 686-938 | STKc_Twitchin_like |
| cd14146 | 685-926 | STKc_MLK4 |
| cd13989 | 686-894 | STKc_IKK |
| cd05574 | 685-926 | STKc_phototropin_like |
| cd07859 | 685-881 | STKc_TDY_MAPK |
| cd14085 | 686-933 | STKc_CaMKIV |
| cd05039 | 686-926 | PTKc_Csk_like |
| cd14173 | 685-933 | STKc_Mnk2 |
| cd14087 | 683-938 | STKc_PSKH1 |
| cd14136 | 686-877 | STKc_SRPK |
| cd14031 | 684-938 | STKc_WNK3 |
| cd14178 | 675-933 | STKc_RSK3_C |
| cd14102 | 685-881 | STKc_PIM3 |
| cd05620 | 685-926 | STKc_nPKC_delta |
| cd07858 | 686-881 | STKc_TEY_MAPK |
| cd07870 | 686-881 | STKc_PFTAIRE2 |
| cd13987 | 686-880 | STKc_SBK1 |
| cd07839 | 686-882 | STKc_CDK5 |
| cd07862 | 686-929 | STKc_CDK6 |
| cd05586 | 686-931 | STKc_Sck1_like |
| cd05148 | 686-928 | PTKc_Srm_Brk |
| cd14191 | 686-926 | STKc_MLCK1 |
| cd14175 | 683-952 | STKc_RSK1_C |
| cd14038 | 686-887 | STKc_IKK_beta |
| cd14198 | 686-938 | STKc_DRAK2 |
| cd14030 | 686-939 | STKc_WNK1 |
| cd13982 | 685-933 | STKc_IRE1 |
| cd07864 | 685-881 | STKc_CDK12 |
| cd05594 | 673-926 | STKc_PKB_alpha |
| cd14071 | 685-926 | STKc_SIK |
| cd13988 | 686-907 | STKc_TBK1 |
| cd14193 | 685-917 | STKc_MLCK4 |
| cd14158 | 686-888 | STKc_IRAK4 |
| cd07873 | 686-881 | STKc_PCTAIRE1 |
| cd14147 | 685-926 | STKc_MLK3 |
| cd05059 | 686-926 | PTKc_Tec_like |
| cd05622 | 685-882 | STKc_ROCK1 |
| cd14183 | 685-933 | STKc_DCKL1 |
| cd14163 | 686-922 | STKc_TSSK3-like |
| cd14047 | 686-933 | STKc_EIF2AK2_PKR |
| cd05060 | 686-926 | PTKc_Syk_like |
| cd05601 | 737-926 | STKc_CRIK |
| cd05084 | 681-926 | PTKc_Fes |
| cd14180 | 675-939 | STKc_MSK2_C |
| cd07853 | 686-938 | STKc_NLK |
| cd05605 | 776-926 | STKc_GRK4_like |
| cd07831 | 686-933 | STKc_MOK |
| cd14177 | 675-950 | STKc_RSK4_C |
| cd14076 | 686-927 | STKc_Kin4 |
| cd14113 | 673-938 | STKc_Trio_C |
| cd14174 | 685-933 | STKc_Mnk1 |
| cd05618 | 655-926 | STKc_aPKC_iota |
| cd14032 | 684-938 | STKc_WNK2_like |
| cd05098 | 671-945 | PTKc_FGFR1 |
| cd14063 | 685-933 | PK_KSR |
| cd05590 | 685-926 | STKc_nPKC_eta |
| cd05099 | 671-968 | PTKc_FGFR4 |
| cd14179 | 677-943 | STKc_MSK1_C |
| cd05085 | 685-926 | PTKc_Fer |
| cd14135 | 686-878 | STKc_PRP4 |
| cd14150 | 686-926 | STKc_A-Raf |
| cd07879 | 686-881 | STKc_p38delta |
| cd14027 | 686-926 | STKc_RIP1 |
| cd14106 | 686-933 | STKc_DRAK |
| cd05598 | 754-926 | STKc_LATS |
| cd05596 | 685-882 | STKc_ROCK |
| cd05608 | 782-970 | STKc_GRK1 |
| cd05063 | 685-938 | PTKc_EphR_A2 |
| cd14000 | 685-929 | STKc_LRRK |
| cd07850 | 685-881 | STKc_JNK |
| cd14664 | 686-885 | STK_BAK1_like |
| cd05057 | 685-881 | PTKc_EGFR_like |
| cd14100 | 685-933 | STKc_PIM1 |
| cd05083 | 686-926 | PTKc_Chk |
| cd14172 | 752-926 | STKc_MAPKAPK3 |
| cd05597 | 743-939 | STKc_DMPK_like |
| cd14108 | 686-928 | STKc_SPEG_rpt1 |
| cd05617 | 685-926 | STKc_aPKC_zeta |
| cd07872 | 686-975 | STKc_PCTAIRE2 |
| cd14182 | 728-939 | STKc_PhKG1 |
| cd05082 | 685-881 | PTKc_Csk |
| cd13986 | 686-933 | STKc_16 |
| cd14001 | 707-886 | PKc_TOPK |
| cd05610 | 686-932 | STKc_MASTL |
| cd05100 | 686-942 | PTKc_FGFR3 |
| cd05588 | 754-926 | STKc_aPKC |
| cd05101 | 671-935 | PTKc_FGFR2 |
| cd14078 | 686-933 | STKc_MELK |
| cd14205 | 686-932 | PTKc_Jak2_rpt2 |
| cd14132 | 673-883 | STKc_CK2_alpha |
| cd14064 | 686-926 | PKc_TNNI3K |
| cd07867 | 669-882 | STKc_CDC2L6 |
| cd14054 | 685-935 | STKc_BMPR2_AMHR2 |
| cd14025 | 686-932 | STKc_RIP4_like |
| cd14134 | 686-881 | PKc_CLK |
| cd14149 | 686-926 | STKc_C-Raf |
| cd05112 | 686-881 | PTKc_Itk |
| cd07875 | 686-881 | STKc_JNK1 |
| cd07874 | 686-940 | STKc_JNK3 |
| cd14170 | 752-938 | STKc_MAPKAPK2 |
| cd14197 | 777-938 | STKc_DRAK1 |
| cd14224 | 669-881 | PKc_DYRK2_3 |
| cd05631 | 685-926 | STKc_GRK4 |
| cd14104 | 686-948 | STKc_Titin |
| cd05632 | 685-881 | STKc_GRK5 |
| cd05606 | 776-926 | STKc_beta_ARK |
| cd05053 | 686-926 | PTKc_FGFR |
| cd07868 | 657-882 | STKc_CDK8 |
| cd07876 | 686-881 | STKc_JNK2 |
| cd05033 | 685-884 | PTKc_EphR |
| cd14171 | 668-933 | STKc_MAPKAPK5 |
| cd05049 | 685-926 | PTKc_Trk |
| cd05115 | 682-919 | PTKc_Zap-70 |
| cd05607 | 672-886 | STKc_GRK7 |
| cd05633 | 685-926 | STKc_GRK3 |
| cd14212 | 685-881 | PKc_YAK1 |
| cd05108 | 685-941 | PTKc_EGFR |
| cd14019 | 686-938 | STKc_Cdc7 |
| cd05080 | 685-933 | PTKc_Tyk2_rpt2 |
| cd14041 | 685-938 | STKc_TLK2 |
| cd14048 | 685-932 | STKc_EIF2AK3_PERK |
| cd14026 | 686-894 | STKc_RIP2 |
| cd05072 | 686-881 | PTKc_Lyn |
| cd14151 | 686-926 | STKc_B-Raf |
| cd05600 | 737-882 | STKc_Sid2p_like |
| cd14115 | 686-933 | STKc_Kalirin_C |
| cd05065 | 685-884 | PTKc_EphR_B |
| cd13998 | 685-929 | STKc_TGFbR-like |
| cd05066 | 685-884 | PTKc_EphR_A |
| cd07869 | 686-965 | STKc_PFTAIRE1 |
| cd14223 | 685-926 | STKc_GRK2 |
| cd14040 | 685-938 | STKc_TLK1 |
| cd05630 | 685-926 | STKc_GRK6 |
| cd05045 | 685-932 | PTKc_RET |
| cd14154 | 686-928 | STKc_LIMK |
| cd07837 | 686-881 | STKc_CdkB_plant |
| cd14022 | 716-933 | PK_TRB2 |
| cd14221 | 686-926 | STKc_LIMK1 |
| cd14017 | 686-880 | STKc_TTBK |
| cd13992 | 706-926 | PK_GC |
| cd13977 | 686-874 | STKc_PDIK1L |
| cd05055 | 671-926 | PTKc_PDGFR |
| cd08226 | 702-954 | PK_STRAD_beta |
| cd05092 | 686-932 | PTKc_TrkA |
| cd05624 | 743-882 | STKc_MRCK_beta |
| cd14036 | 683-933 | STKc_GAK |
| cd05081 | 685-932 | PTKc_Jak3_rpt2 |
| cd05114 | 686-933 | PTKc_Tec_Rlk |
| cd05034 | 686-926 | PTKc_Src_like |
| cd14016 | 686-846 | STKc_CK1 |
| cd05032 | 686-926 | PTKc_InsR_like |
| cd14110 | 688-881 | STKc_obscurin_rpt2 |
| cd14068 | 685-926 | STKc_LRRK2 |
| cd14056 | 685-926 | STKc_TGFbR_I |
| cd14156 | 724-937 | PKc_LIMK_like_unk |
| cd05056 | 685-881 | PTKc_FAK |
| cd14138 | 686-933 | PTKc_Wee1a |
| cd05037 | 686-935 | PTK_Jak_rpt1 |
| cd14112 | 686-938 | STKc_Unc-89_rpt2 |
| cd14225 | 669-881 | PKc_DYRK4 |
| cd14051 | 685-933 | PTKc_Wee1 |
| cd14065 | 686-872 | PKc_LIMK_like |
| cd14226 | 675-924 | PKc_DYRK1 |
| cd14222 | 686-879 | STKc_LIMK2 |
| cd05052 | 686-926 | PTKc_Abl |
| cd14152 | 686-909 | STKc_KSR1 |
| cd05061 | 686-926 | PTKc_InsR |
| cd05111 | 685-941 | PTK_HER3 |
| cd05627 | 737-917 | STKc_NDR2 |
| cd05626 | 686-949 | STKc_LATS2 |
| cd14053 | 688-929 | STKc_ACVR2 |
| cd05628 | 737-917 | STKc_NDR1 |
| cd05073 | 686-926 | PTKc_Hck |
| cd05113 | 686-933 | PTKc_Btk_Bmx |
| cd05067 | 686-926 | PTKc_Lck_Blk |
| cd05054 | 685-932 | PTKc_VEGFR |
| cd13975 | 686-926 | PKc_Dusty |
| cd14018 | 722-930 | STKc_PINK1 |
| cd05623 | 743-882 | STKc_MRCK_alpha |
| cd05629 | 737-881 | STKc_NDR_like_fungal |
| cd05040 | 686-926 | PTKc_Ack_like |
| cd14153 | 685-933 | PK_KSR2 |
| cd05109 | 685-941 | PTKc_HER2 |
| cd05071 | 684-926 | PTKc_Src |
| cd05050 | 676-888 | PTKc_Musk |
| cd14042 | 706-926 | PK_GC-A_B |
| cd05036 | 686-928 | PTKc_ALK_LTK |
| cd05062 | 686-892 | PTKc_IGF-1R |
| cd05044 | 686-881 | PTKc_c-ros |
| cd05093 | 686-926 | PTKc_TrkB |
| cd05090 | 686-932 | PTKc_Ror1 |
| cd05110 | 685-879 | PTKc_HER4 |
| cd14142 | 686-952 | STKc_ACVR1_ALK1 |
| cd13976 | 720-933 | PK_TRB |
| cd05047 | 685-934 | PTKc_Tie |
| cd14055 | 685-929 | STKc_TGFbR2_like |
| cd13980 | 782-933 | STKc_Vps15 |
| cd14057 | 692-926 | PK_ILK |
| cd14155 | 725-874 | PKc_TESK |
| cd05048 | 686-882 | PTKc_Ror |
| cd13984 | 732-938 | PK_NRBP1_like |
| cd05087 | 686-932 | PTKc_Aatyk1 |
| cd14139 | 686-932 | PTKc_Wee1b |
| cd05068 | 686-881 | PTKc_Frk_like |
| cd14045 | 706-883 | PK_GC_unk |
| cd08227 | 722-939 | PK_STRAD_alpha |
| cd05116 | 686-926 | PTKc_Syk |
| cd05625 | 686-922 | STKc_LATS1 |
| cd14011 | 773-938 | PK_SCY1_like |
| cd14203 | 686-926 | PTKc_Src_Fyn_like |
| cd14024 | 720-938 | PK_TRB3 |
| cd13968 | 686-824 | PKc_like |
| cd14141 | 685-876 | STKc_ACVR2a |
| cd14214 | 686-877 | PKc_CLK3 |
| cd14049 | 673-874 | STKc_EIF2AK1_HRI |
| cd05035 | 685-926 | PTKc_TAM |
| cd05094 | 686-932 | PTKc_TrkC |
| cd14129 | 686-888 | STKc_TTBK2 |
| cd14043 | 730-937 | PK_GC-2D |
| cd05051 | 712-927 | PTKc_DDR |
| cd05089 | 685-926 | PTKc_Tie1 |
| cd14207 | 783-926 | PTKc_VEGFR1 |
| cd14130 | 686-915 | STKc_TTBK1 |
| smart00220 | 685-938 | S_TKc |
| pfam00069 | 685-938 | Pkinase |
| COG0515 | 685-1017 | SPS1 |
| pfam07714 | 685-935 | Pkinase_Tyr |
| smart00221 | 685-933 | STYKc |
| smart00219 | 685-933 | TyrKc |
| PLN00034 | 682-949 | PLN00034 |
| PTZ00263 | 686-926 | PTZ00263 |
| PTZ00024 | 686-881 | PTZ00024 |
| PLN00009 | 686-881 | PLN00009 |
| PTZ00036 | 647-938 | PTZ00036 |
| PTZ00266 | 665-904 | PTZ00266 |
| PTZ00267 | 713-939 | PTZ00267 |
| PTZ00426 | 645-882 | PTZ00426 |
| PTZ00283 | 767-933 | PTZ00283 |
| PHA03212 | 725-883 | PHA03212 |
| PHA03390 | 725-940 | pk1 |
| TIGR03903 | 703-879 | TOMM_kin_cyc |
| PHA03209 | 785-874 | PHA03209 |
| PRK13184 | 686-968 | pknD |
| PHA03207 | 725-882 | PHA03207 |
Ontology Information
| HPRD ID | 2558 |
|---|---|
| Molecular Class | Serine/threonine kinase |
| Molecular Function | Transcription regulator activity (GO:0030528) |
| Biological Process | Regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0019219) |
Drug Information
No matching records could be found.