CoReCG

Evidence Information

Pubmed ID	Year	Sample Information	Techniques	Mechanism	Fold Change	Remark
23027623	2012	Cell line : - Source : Twin Cities Metropolitan Area or a seven-county area of Utah or enrolled in the Kaiser Permanente Medical Care Program of Northern California (KPMCP). Sample Type : Population-based case-control No. of Sample : Colon 1555 cases, 1956 controls; rectal 754 cases, 959 controls Stage : -	TagSNP selection and genotyping	Polymorhpism	-	-

Gene Details

NC_000006.11 (136878184..137113656, complement)
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Gene Type	protein coding
Gene Family	Mitogen-activated protein kinase cascade / Kinase kinase kinases
Description	Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MAPKKK5 contains 1,374 amino acids with all 11 kinase subdomains. Northern blot analysis shows that MAPKKK5 transcript is abundantly expressed in human heart and pancreas. The MAPKKK5 protein phosphorylates and activates MKK4 (aliases SERK1, MAPKK4) in vitro, and activates c-Jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK) during transient expression in COS and 293 cells; MAPKKK5 does not activate MAPK/ERK. [provided by RefSeq, Jul 2008]
Chromosome	6
Location	6q22.33
Start	136878184
End	137113656
Strand	-
Gene Sequence	Download Select all
Length	235473
OMIM ID	602448
HGNC ID	HGNC:6857
Unigene ID	Hs.186486
Ensembl ID	ENSG00000197442
PharmGKB ID	PA30601

mRNA Information

mRNA ID	XM_011535838.1
Exon	join(1..1342,72463..72602,87919..87942,94370..94563, 95665..95833,96995..97101,98742..98912,123657..123769, 133674..133833,136592..136745,141961..142068, 150483..150532,153414..153509,155646..155727, 170071..170204,178766..178893,179796..179932, 181665..181770,187686..187843,191073..191250, 192010..192030,200435..200615,200711..200879, 209312..209497,212646..212751,225178..225421, 230437..230549,231407..231519,234176..234252, 235234..236006)
mRNA Sequence	Download Select all
Length	5734

CDS Information

Location	895..5022
CDS Sequence	Download Select all
CCDS ID	CCDS5179.1

Protein Information

Protein ID	XP_011534140.1
Protein Name	mitogen-activated protein kinase kinase kinase 5
Molecular Wt. (Da)	0
Protein Sequence	Download Select all
Length	1375
Uniprot ID	P16035
Ensembl Protein ID	ENSP00000262768

Post-translational Modification Information (Source : HPRD)

Residue	Type	site
T	Phosphorylation	842
S	Phosphorylation	966
T	Dephosphorylation	842
T	Phosphorylation	838
S	Phosphorylation	83
S	Phosphorylation	1029
S	Phosphorylation	1033

Enzyme Information

No matching records could be found.

PPi Information

(Click to view network : Source STRING) View

Interactant Gene ID (Source: HPRD)	Gene Symbol	HPRD ID	Ref Seq ID	Technique	References
409	ARRB2	147	NP_004304.1	in vivo	11356842
993	CDC25A	305	NP_001780.2	in vitro;in vivo;yeast 2-hybrid	11416155
2745	GLRX	2707	NP_002055.1	in vitro	12244106
2944	GSTM1	707	NP_000552.2	in vitro;in vivo	1 127 828 912 077 130
3303	HSPA1A	774	NP_005336.3	in vitro;in vivo	12391142
5610	EIF2AK2	1468	NP_002750.1	in vitro;in vivo	12473108
5894	RAF1	1265	NP_002871.1	in vitro;in vivo	11427728
7139	TNNT2	1844	NP_000355.2	in vivo	12819028
7164	TPD52L1	7236	NP_003278.1	in vivo	14761963
7186	TRAF2	3538	NP_066961.2	in vitro;in vivo	977 497 710 523 862
7188	TRAF5	3834	NP_004610.1	in vitro;in vivo	10523862
7189	TRAF6	3833	NP_665802.1	in vitro;in vivo	10523862
7295	TXN	1761	NP_003320.2	in vitro;in vivo;yeast 2-hybrid	120 890 639 564 042
7533	YWHAH	215	NP_003396.1	yeast 2-hybrid	15023544
7534	YWHAZ	3183	NP_003397.1	in vitro;in vivo	1 041 190 611 336 670
10016	PDCD6	3035	NP_037364.1	in vitro	12372597
10971	YWHAQ	886	NP_006817.1	yeast 2-hybrid	15023544

Pathway Information

Pathway Name	Pathway ID
Amyotrophic lateral sclerosis (ALS)	hsa05014
MAPK signaling pathway	hsa04010
Neurotrophin signaling pathway	hsa04722
Non-alcoholic fatty liver disease (NAFLD)	hsa04932
Protein processing in endoplasmic reticulum	hsa04141
Sphingolipid signaling pathway	hsa04071
TNF signaling pathway	hsa04668

Structure Information

No matching records could be found.

Domain Information

ID	Location	Description
cd06624	671-938	STKc_ASK
cl21453	671-938	PKc_like superfamily
pfam13281	165-545	DUF4071
cl19991	165-545	DUF4071 superfamily
cd06606	685-938	STKc_MAPKKK
cd05122	682-938	PKc_STE
cd06632	686-938	STKc_MEKK1_plant
cd06626	687-938	STKc_MEKK4
cd06627	686-933	STKc_Cdc7_like
cd06625	685-937	STKc_MEKK3_like
cd06629	686-938	STKc_Bck1_like
cd06631	685-938	STKc_YSK4
cd06628	685-938	STKc_Byr2_like
cd06612	672-938	STKc_MST1_2
cd08215	685-938	STKc_Nek
cd06630	685-934	STKc_MEKK1
cd06623	685-943	PKc_MAPKK_plant_like
cd05117	685-937	STKc_CAMK
cd00180	686-933	PKc
cd06614	682-939	STKc_PAK
cd14007	686-939	STKc_Aurora
cd06609	685-944	STKc_MST3_like
cd13999	686-926	STKc_MAP3K-like
cd14014	685-937	STKc_PknB_like
cd05123	686-931	STKc_AGC
cd06613	686-937	STKc_MAP4K3_like
cd14003	685-937	STKc_AMPK-like
cd14008	686-938	STKc_LKB1_CaMKK
cd06652	685-937	STKc_MEKK2
cd06653	685-937	STKc_MEKK3_like_u1
cd06610	674-933	STKc_OSR1_SPAK
cd14099	686-938	STKc_PLK
cd06651	685-940	STKc_MEKK3
cd06917	685-943	STKc_NAK1_like
cd05118	685-938	STKc_CMGC
cd13983	684-938	STKc_WNK
cd06608	685-938	STKc_myosinIII_N_like
cd06605	685-939	PKc_MAPKK
cd08217	685-938	STKc_Nek2
cd06621	686-945	PKc_Pek1_like
cd06611	686-948	STKc_SLK_like
cd07829	675-938	STKc_CDK_like
cd08220	685-933	STKc_Nek8
cd06647	686-939	STKc_PAK_I
cd08530	685-933	STKc_CNK2-like
cd05581	685-926	STKc_PDK1
cd08225	685-938	STKc_Nek5
cd06648	681-939	STKc_PAK_II
cd05572	686-926	STKc_cGK
cd05579	688-930	STKc_MAST_like
cd14080	686-933	STKc_TSSK-like
cd14098	685-933	STKc_Rad53_Cds1
cd14137	685-937	STKc_GSK3
cd08529	686-933	STKc_FA2-like
cd14009	686-926	STKc_ATG1_ULK_like
cd05580	685-926	STKc_PKA_like
cd08218	686-938	STKc_Nek1
cd06643	686-945	STKc_SLK
cd06654	686-953	STKc_PAK1
cd08224	686-934	STKc_Nek6_7
cd14189	685-938	STKc_PLK3
cd14188	685-938	STKc_PLK2
cd06656	686-953	STKc_PAK3
cd00192	685-933	PTKc
cd07840	686-937	STKc_CDK9_like
cd06655	686-964	STKc_PAK2
cd14084	685-933	STKc_Chk2
cd06620	686-946	PKc_Byr1_like
cd06622	686-939	PKc_PBS2_like
cd06640	686-944	STKc_MST4
cd14663	685-927	STKc_SnRK3
cd14006	686-933	STKc_MLCK-like
cd07833	685-933	STKc_CDKL
cd13996	685-933	STKc_EIF2AK
cd05611	688-930	STKc_Rim15_like
cd13994	686-938	STKc_HAL4_like
cd06641	686-944	STKc_MST3
cd14002	685-938	STKc_STK36
cd06638	686-938	STKc_myosinIIIA_N
cd06644	686-944	STKc_STK10
cd14131	686-938	PKc_Mps1
cd08222	686-938	STKc_Nek11
cd07834	685-939	STKc_MAPK
cd06607	686-938	STKc_TAO
cd06642	686-944	STKc_STK25
cd06646	672-938	STKc_MAP4K5
cd13993	685-933	STKc_Pat1_like
cd08528	686-926	STKc_Nek10
cd06645	686-938	STKc_MAP4K3
cd14166	685-926	STKc_CaMKI_gamma
cd05612	686-926	STKc_PRKX_like
cd08228	686-926	STKc_Nek6
cd14167	683-926	STKc_CaMKI_alpha
cd08219	685-933	STKc_Nek3
cd07832	686-881	STKc_CCRK
cd14069	686-938	STKc_Chk1
cd06659	682-938	STKc_PAK6
cd14081	686-926	STKc_BRSK1_2
cd14059	686-926	STKc_MAP3K12_13
cd07841	686-939	STKc_CDK7
cd14187	686-938	STKc_PLK1
cd08223	685-938	STKc_Nek4
cd06639	686-939	STKc_myosinIIIB_N
cd14086	674-933	STKc_CaMKII
cd06637	685-951	STKc_TNIK
cd05583	752-936	STKc_MSK_N
cd06617	686-954	PKc_MKK3_6
cd14120	686-926	STKc_ULK1_2-like
cd14097	686-933	STKc_STK33
cd06658	686-941	STKc_PAK5
cd06636	685-892	STKc_MAP4K4_6_N
cd13995	688-938	STKc_MAP3K8
cd13997	686-933	PKc_Wee1_like
cd13979	684-930	STKc_Mos
cd14119	686-927	STKc_LKB1
cd14083	685-926	STKc_CaMKI
cd07838	686-938	STKc_CDK4_6_like
cd14012	720-937	PK_eIF2AK_GCN2_rpt1
cd06615	684-943	PKc_MEK
cd14094	685-939	STKc_CASK
cd06633	686-939	STKc_TAO3
cd13978	686-926	STKc_RIP
cd06657	684-938	STKc_PAK4
cd07835	686-881	STKc_CDK1_CdkB_like
cd14209	679-882	STKc_PKA
cd07846	685-937	STKc_CDKL2_3
cd07849	685-881	STKc_ERK1_2_like
cd05584	685-931	STKc_p70S6K
cd14186	685-938	STKc_PLK4
cd14116	686-934	STKc_Aurora-A
cd07866	674-879	STKc_BUR1
cd07845	686-881	STKc_CDK10
cd14004	685-938	STKc_PASK
cd07836	686-881	STKc_Pho85
cd05570	684-926	STKc_PKC
cd07830	686-933	STKc_MAK_like
cd14202	685-938	STKc_ULK1
cd14005	685-926	STKc_PIM
cd06634	686-938	STKc_TAO2
cd14010	677-937	STKc_ULK4
cd14096	686-938	STKc_RCK1-like
cd14118	686-926	STKc_CAMKK
cd14210	669-938	PKc_DYRK
cd14665	686-926	STKc_SnRK2-3
cd14050	685-933	PKc_Myt1
cd08229	686-926	STKc_Nek7
cd14095	685-936	STKc_DCKL
cd07842	687-937	STKc_CDK8_like
cd08221	685-938	STKc_Nek9
cd14201	674-926	STKc_ULK2
cd06635	686-938	STKc_TAO1
cd14121	686-926	STKc_ULK3
cd14169	686-926	STKc_CaMKI_beta
cd13985	683-933	STKc_GAK_like
cd06618	686-939	PKc_MKK7
cd05592	685-926	STKc_nPKC_theta_like
cd14185	685-933	STKc_DCKL3
cd05613	685-926	STKc_MSK1_N
cd14162	685-881	STKc_TSSK4-like
cd07860	686-881	STKc_CDK2_3
cd05578	685-926	STKc_Yank1
cd14061	685-935	STKc_MLK
cd14194	676-933	STKc_DAPK1
cd05573	685-918	STKc_ROCK_NDR_like
cd14200	686-938	STKc_CaMKK1
cd14091	674-933	STKc_RSK_C
cd14093	697-938	STKc_PhKG
cd14117	686-944	STKc_Aurora-B_like
cd14662	686-926	STKc_SnRK2
cd05616	684-926	STKc_cPKC_beta
cd14066	686-926	STKc_IRAK
cd14107	686-938	STKc_obscurin_rpt1
cd05587	754-926	STKc_cPKC
cd05575	685-926	STKc_SGK
cd07854	686-881	STKc_MAPK4_6
cd14133	685-938	PKc_DYRK_like
cd05571	685-926	STKc_PKB
cd07843	689-886	STKc_CDC2L1
cd13990	686-927	STKc_TLK
cd07851	686-881	STKc_p38
cd14148	685-926	STKc_MLK2
cd06650	686-941	PKc_MEK1
cd14101	685-939	STKc_PIM2
cd14070	686-938	STKc_HUNK
cd07856	686-881	STKc_Sty1_Hog1
cd05614	685-926	STKc_MSK2_N
cd07852	686-939	STKc_MAPK15-like
cd14082	685-883	STKc_PKD
cd07861	686-882	STKc_CDK1_euk
cd05595	685-926	STKc_PKB_beta
cd07848	685-881	STKc_CDKL5
cd13991	686-932	STKc_NIK
cd14060	687-933	STKc_MLTK
cd07847	686-933	STKc_CDKL1_4
cd05589	685-926	STKc_PKN
cd14145	685-933	STKc_MLK1
cd07865	686-879	STKc_CDK9
cd07855	675-881	STKc_ERK5
cd05038	686-932	PTKc_Jak_rpt2
cd14103	686-933	STKc_MLCK
cd14073	675-881	STKc_NUAK
cd06619	683-938	PKc_MKK5
cd14033	686-938	STKc_WNK4
cd06616	673-939	PKc_MKK4
cd07857	686-881	STKc_MPK1
cd14075	686-938	STKc_NIM1
cd05593	685-926	STKc_PKB_gamma
cd07880	686-881	STKc_p38gamma
cd14090	677-933	STKc_Mnk
cd05609	689-926	STKc_MAST
cd14079	686-938	STKc_AMPK_alpha
cd05615	684-926	STKc_cPKC_alpha
cd14077	686-927	STKc_Kin1_2
cd05603	685-882	STKc_SGK2
cd14192	685-938	STKc_MLCK3
cd14181	672-938	STKc_PhKG2
cd07844	685-962	STKc_PCTAIRE_like
cd14164	686-926	STKc_TSSK6-like
cd05602	685-882	STKc_SGK1
cd14111	687-938	STKc_SPEG_rpt2
cd14165	686-938	STKc_TSSK1_2-like
cd05599	737-937	STKc_NDR_like
cd14089	683-939	STKc_MAPKAPK
cd14074	686-938	STKc_SNRK
cd07877	686-881	STKc_p38alpha
cd14072	686-938	STKc_MARK
cd05621	679-882	STKc_ROCK2
cd05604	685-931	STKc_SGK3
cd07863	686-938	STKc_CDK4
cd14052	686-876	PTKc_Wee1_fungi
cd14168	685-926	STKc_CaMKI_delta
cd14161	671-881	STKc_NUAK2
cd14199	686-926	STKc_CaMKK2
cd14092	676-947	STKc_MSK_C
cd14196	686-933	STKc_DAPK2
cd14062	686-926	STKc_Raf
cd08216	684-939	PK_STRAD
cd14058	686-926	STKc_TAK1
cd14039	686-887	STKc_IKK_alpha
cd05079	686-933	PTKc_Jak1_rpt2
cd14046	685-936	STKc_EIF2AK4_GCN2_rpt2
cd05582	685-926	STKc_RSK_N
cd14176	675-933	STKc_RSK2_C
cd14037	685-926	STKc_NAK_like
cd14109	675-939	PK_Unc-89_rpt1
cd14088	694-938	STKc_CaMK_like
cd05577	686-926	STKc_GRK
cd14190	683-915	STKc_MLCK2
cd05585	685-949	STKc_YPK1_like
cd14105	686-933	STKc_DAPK
cd07878	686-881	STKc_p38beta
cd14184	685-933	STKc_DCKL2
cd05619	685-926	STKc_nPKC_theta
cd14195	686-940	STKc_DAPK3
cd05041	686-926	PTKc_Fes_like
cd07871	686-881	STKc_PCTAIRE3
cd05591	685-881	STKc_nPKC_epsilon
cd06649	678-880	PKc_MEK2
cd14114	686-938	STKc_Twitchin_like
cd14146	685-926	STKc_MLK4
cd13989	686-894	STKc_IKK
cd05574	685-926	STKc_phototropin_like
cd07859	685-881	STKc_TDY_MAPK
cd14085	686-933	STKc_CaMKIV
cd05039	686-926	PTKc_Csk_like
cd14173	685-933	STKc_Mnk2
cd14087	683-938	STKc_PSKH1
cd14136	686-877	STKc_SRPK
cd14031	684-938	STKc_WNK3
cd14178	675-933	STKc_RSK3_C
cd14102	685-881	STKc_PIM3
cd05620	685-926	STKc_nPKC_delta
cd07858	686-881	STKc_TEY_MAPK
cd07870	686-881	STKc_PFTAIRE2
cd13987	686-880	STKc_SBK1
cd07839	686-882	STKc_CDK5
cd07862	686-929	STKc_CDK6
cd05586	686-931	STKc_Sck1_like
cd05148	686-928	PTKc_Srm_Brk
cd14191	686-926	STKc_MLCK1
cd14175	683-952	STKc_RSK1_C
cd14038	686-887	STKc_IKK_beta
cd14198	686-938	STKc_DRAK2
cd14030	686-939	STKc_WNK1
cd13982	685-933	STKc_IRE1
cd07864	685-881	STKc_CDK12
cd05594	673-926	STKc_PKB_alpha
cd14071	685-926	STKc_SIK
cd13988	686-907	STKc_TBK1
cd14193	685-917	STKc_MLCK4
cd14158	686-888	STKc_IRAK4
cd07873	686-881	STKc_PCTAIRE1
cd14147	685-926	STKc_MLK3
cd05059	686-926	PTKc_Tec_like
cd05622	685-882	STKc_ROCK1
cd14183	685-933	STKc_DCKL1
cd14163	686-922	STKc_TSSK3-like
cd14047	686-933	STKc_EIF2AK2_PKR
cd05060	686-926	PTKc_Syk_like
cd05601	737-926	STKc_CRIK
cd05084	681-926	PTKc_Fes
cd14180	675-939	STKc_MSK2_C
cd07853	686-938	STKc_NLK
cd05605	776-926	STKc_GRK4_like
cd07831	686-933	STKc_MOK
cd14177	675-950	STKc_RSK4_C
cd14076	686-927	STKc_Kin4
cd14113	673-938	STKc_Trio_C
cd14174	685-933	STKc_Mnk1
cd05618	655-926	STKc_aPKC_iota
cd14032	684-938	STKc_WNK2_like
cd05098	671-945	PTKc_FGFR1
cd14063	685-933	PK_KSR
cd05590	685-926	STKc_nPKC_eta
cd05099	671-968	PTKc_FGFR4
cd14179	677-943	STKc_MSK1_C
cd05085	685-926	PTKc_Fer
cd14135	686-878	STKc_PRP4
cd14150	686-926	STKc_A-Raf
cd07879	686-881	STKc_p38delta
cd14027	686-926	STKc_RIP1
cd14106	686-933	STKc_DRAK
cd05598	754-926	STKc_LATS
cd05596	685-882	STKc_ROCK
cd05608	782-970	STKc_GRK1
cd05063	685-938	PTKc_EphR_A2
cd14000	685-929	STKc_LRRK
cd07850	685-881	STKc_JNK
cd14664	686-885	STK_BAK1_like
cd05057	685-881	PTKc_EGFR_like
cd14100	685-933	STKc_PIM1
cd05083	686-926	PTKc_Chk
cd14172	752-926	STKc_MAPKAPK3
cd05597	743-939	STKc_DMPK_like
cd14108	686-928	STKc_SPEG_rpt1
cd05617	685-926	STKc_aPKC_zeta
cd07872	686-975	STKc_PCTAIRE2
cd14182	728-939	STKc_PhKG1
cd05082	685-881	PTKc_Csk
cd13986	686-933	STKc_16
cd14001	707-886	PKc_TOPK
cd05610	686-932	STKc_MASTL
cd05100	686-942	PTKc_FGFR3
cd05588	754-926	STKc_aPKC
cd05101	671-935	PTKc_FGFR2
cd14078	686-933	STKc_MELK
cd14205	686-932	PTKc_Jak2_rpt2
cd14132	673-883	STKc_CK2_alpha
cd14064	686-926	PKc_TNNI3K
cd07867	669-882	STKc_CDC2L6
cd14054	685-935	STKc_BMPR2_AMHR2
cd14025	686-932	STKc_RIP4_like
cd14134	686-881	PKc_CLK
cd14149	686-926	STKc_C-Raf
cd05112	686-881	PTKc_Itk
cd07875	686-881	STKc_JNK1
cd07874	686-940	STKc_JNK3
cd14170	752-938	STKc_MAPKAPK2
cd14197	777-938	STKc_DRAK1
cd14224	669-881	PKc_DYRK2_3
cd05631	685-926	STKc_GRK4
cd14104	686-948	STKc_Titin
cd05632	685-881	STKc_GRK5
cd05606	776-926	STKc_beta_ARK
cd05053	686-926	PTKc_FGFR
cd07868	657-882	STKc_CDK8
cd07876	686-881	STKc_JNK2
cd05033	685-884	PTKc_EphR
cd14171	668-933	STKc_MAPKAPK5
cd05049	685-926	PTKc_Trk
cd05115	682-919	PTKc_Zap-70
cd05607	672-886	STKc_GRK7
cd05633	685-926	STKc_GRK3
cd14212	685-881	PKc_YAK1
cd05108	685-941	PTKc_EGFR
cd14019	686-938	STKc_Cdc7
cd05080	685-933	PTKc_Tyk2_rpt2
cd14041	685-938	STKc_TLK2
cd14048	685-932	STKc_EIF2AK3_PERK
cd14026	686-894	STKc_RIP2
cd05072	686-881	PTKc_Lyn
cd14151	686-926	STKc_B-Raf
cd05600	737-882	STKc_Sid2p_like
cd14115	686-933	STKc_Kalirin_C
cd05065	685-884	PTKc_EphR_B
cd13998	685-929	STKc_TGFbR-like
cd05066	685-884	PTKc_EphR_A
cd07869	686-965	STKc_PFTAIRE1
cd14223	685-926	STKc_GRK2
cd14040	685-938	STKc_TLK1
cd05630	685-926	STKc_GRK6
cd05045	685-932	PTKc_RET
cd14154	686-928	STKc_LIMK
cd07837	686-881	STKc_CdkB_plant
cd14022	716-933	PK_TRB2
cd14221	686-926	STKc_LIMK1
cd14017	686-880	STKc_TTBK
cd13992	706-926	PK_GC
cd13977	686-874	STKc_PDIK1L
cd05055	671-926	PTKc_PDGFR
cd08226	702-954	PK_STRAD_beta
cd05092	686-932	PTKc_TrkA
cd05624	743-882	STKc_MRCK_beta
cd14036	683-933	STKc_GAK
cd05081	685-932	PTKc_Jak3_rpt2
cd05114	686-933	PTKc_Tec_Rlk
cd05034	686-926	PTKc_Src_like
cd14016	686-846	STKc_CK1
cd05032	686-926	PTKc_InsR_like
cd14110	688-881	STKc_obscurin_rpt2
cd14068	685-926	STKc_LRRK2
cd14056	685-926	STKc_TGFbR_I
cd14156	724-937	PKc_LIMK_like_unk
cd05056	685-881	PTKc_FAK
cd14138	686-933	PTKc_Wee1a
cd05037	686-935	PTK_Jak_rpt1
cd14112	686-938	STKc_Unc-89_rpt2
cd14225	669-881	PKc_DYRK4
cd14051	685-933	PTKc_Wee1
cd14065	686-872	PKc_LIMK_like
cd14226	675-924	PKc_DYRK1
cd14222	686-879	STKc_LIMK2
cd05052	686-926	PTKc_Abl
cd14152	686-909	STKc_KSR1
cd05061	686-926	PTKc_InsR
cd05111	685-941	PTK_HER3
cd05627	737-917	STKc_NDR2
cd05626	686-949	STKc_LATS2
cd14053	688-929	STKc_ACVR2
cd05628	737-917	STKc_NDR1
cd05073	686-926	PTKc_Hck
cd05113	686-933	PTKc_Btk_Bmx
cd05067	686-926	PTKc_Lck_Blk
cd05054	685-932	PTKc_VEGFR
cd13975	686-926	PKc_Dusty
cd14018	722-930	STKc_PINK1
cd05623	743-882	STKc_MRCK_alpha
cd05629	737-881	STKc_NDR_like_fungal
cd05040	686-926	PTKc_Ack_like
cd14153	685-933	PK_KSR2
cd05109	685-941	PTKc_HER2
cd05071	684-926	PTKc_Src
cd05050	676-888	PTKc_Musk
cd14042	706-926	PK_GC-A_B
cd05036	686-928	PTKc_ALK_LTK
cd05062	686-892	PTKc_IGF-1R
cd05044	686-881	PTKc_c-ros
cd05093	686-926	PTKc_TrkB
cd05090	686-932	PTKc_Ror1
cd05110	685-879	PTKc_HER4
cd14142	686-952	STKc_ACVR1_ALK1
cd13976	720-933	PK_TRB
cd05047	685-934	PTKc_Tie
cd14055	685-929	STKc_TGFbR2_like
cd13980	782-933	STKc_Vps15
cd14057	692-926	PK_ILK
cd14155	725-874	PKc_TESK
cd05048	686-882	PTKc_Ror
cd13984	732-938	PK_NRBP1_like
cd05087	686-932	PTKc_Aatyk1
cd14139	686-932	PTKc_Wee1b
cd05068	686-881	PTKc_Frk_like
cd14045	706-883	PK_GC_unk
cd08227	722-939	PK_STRAD_alpha
cd05116	686-926	PTKc_Syk
cd05625	686-922	STKc_LATS1
cd14011	773-938	PK_SCY1_like
cd14203	686-926	PTKc_Src_Fyn_like
cd14024	720-938	PK_TRB3
cd13968	686-824	PKc_like
cd14141	685-876	STKc_ACVR2a
cd14214	686-877	PKc_CLK3
cd14049	673-874	STKc_EIF2AK1_HRI
cd05035	685-926	PTKc_TAM
cd05094	686-932	PTKc_TrkC
cd14129	686-888	STKc_TTBK2
cd14043	730-937	PK_GC-2D
cd05051	712-927	PTKc_DDR
cd05089	685-926	PTKc_Tie1
cd14207	783-926	PTKc_VEGFR1
cd14130	686-915	STKc_TTBK1
smart00220	685-938	S_TKc
pfam00069	685-938	Pkinase
COG0515	685-1017	SPS1
pfam07714	685-935	Pkinase_Tyr
smart00221	685-933	STYKc
smart00219	685-933	TyrKc
PLN00034	682-949	PLN00034
PTZ00263	686-926	PTZ00263
PTZ00024	686-881	PTZ00024
PLN00009	686-881	PLN00009
PTZ00036	647-938	PTZ00036
PTZ00266	665-904	PTZ00266
PTZ00267	713-939	PTZ00267
PTZ00426	645-882	PTZ00426
PTZ00283	767-933	PTZ00283
PHA03212	725-883	PHA03212
PHA03390	725-940	pk1
TIGR03903	703-879	TOMM_kin_cyc
PHA03209	785-874	PHA03209
PRK13184	686-968	pknD
PHA03207	725-882	PHA03207

Ontology Information

HPRD ID	2558
Molecular Class	Serine/threonine kinase
Molecular Function	Transcription regulator activity (GO:0030528)
Biological Process	Regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0019219)

SNP Information

View SNP Geneview Report