CoReCG

Evidence Information

Pubmed ID	Year	Sample Information	Techniques	Mechanism	Fold Change	Remark
24503701	2014	Cell line : - Source : Department of Anatomical Pathology, Royal North Shore Hospital, Sydney Sample Type : Case control study No. of Sample : 1421 Stage : -	Immunohistochemistry	Up-regulation	-	Myc status as determined by IHC alone can be used to predict overall survival in patients with CRC undergoing surgical resection. MYC over-expression was found in 980 (69%) of CRCs and was associated with tumor stage and DNA mismatch repair/BRAF status.
23613397	2013	Cell line : - Source : - Sample Type : Parafin embeded CRC tissue sample No. of Sample : 60 Stage : -	Microarray, Immunohistochemistry	Up-regulation	-	c-MYC overexpression is correlated with progressive disease - due to colon adenocarcinoma dedifferentiation - inhibition of its activity combined with h-TERT regulated expression is a new target for novel therapeutic regimens.

Gene Details

Chromosome 8 - NC_000008.11 (127736069..127741434)
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Gene Type	protein coding
Gene Family	Basic helix-loop-helix proteins
Description	The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.
Chromosome	8
Location	8q24
Start	127736069
End	127741434
Strand	+
Gene Sequence	>gi\|568815590:127736069-127741434 Homo sapiens chromosome 8, GRCh38.p2 Primary Assembly GACCCCCGAGCTGTGCTGCTCGCGGCCGCCACCGCCGGGCCCCGGCCGTCCCTGGCTCCCCTCCTGCCTC GAGAAGGGCAGGGCTTCTCAGAGGCTTGGCGGGAAAAAGAACGGAGGGAGGGATCGCGCTGAGTATAAAA GCCGGTTTTCGGGGCTTTATCTAACTCGCTGTAGTAATTCCAGCGAGAGGCAGAGGGAGCGAGCGGGCGG CCGGCTAGGGTGGAAGAGCCGGGCGAGCAGAGCTGCGCTGCGGGCGTCCTGGGAAGGGAGATCCGGAGCG AATAGGGGGCTTCGCCTCTGGCCCAGCCCTCCCGCTGATCCCCCAGCCAGCGGTCCGCAACCCTTGCCGC ATCCACGAAACTTTGCCCATAGCAGCGGGCGGGCACTTTGCACTGGAACTTACAACACCCGAGCAAGGAC GCGACTCTCCCGACGCGGGGAGGCTATTCTGCCCATTTGGGGACACTTCCCCGCCGCTGCCAGGACCCGC TTCTCTGAAAGGCTCTCCTTGCAGCTGCTTAGACGCTGGATTTTTTTCGGGTAGTGGAAAACCAGGTAAG CACCGAAGTCCACTTGCCTTTTAATTTATTTTTTTATCACTTTAATGCTGAGATGAGTCGAATGCCTAAA TAGGGTGTCTTTTCTCCCATTCCTGCGCTATTGACACTTTTCTCAGAGTAGTTATGGTAACTGGGGCTGG GGTGGGGGGTAATCCAGAACTGGATCGGGGTAAAGTGACTTGTCAAGATGGGAGAGGAGAAGGCAGAGGG AAAACGGGAATGGTTTTTAAGACTACCCTTTCGAGATTTCTGCCTTATGAATATATTCACGCTGACTCCC GGCCGGTCGGACATTCCTGCTTTATTGTGTTAATTGCTCTCTGGGTTTTGGGGGGCTGGGGGTTGCTTTG CGGTGGGCAGAAAGCCCCTTGCATCCTGAGCTCCTTGGAGTAGGGACCGCATATCGCCTGTGTGAGCCAG ATCGCTCCGCAGCCGCTGACTTGTCCCCGTCTCCGGGAGGGCATTTAAATTTCGGCTCACCGCATTTCTG ACAGCCGGAGACGGACACTGCGGCGCGTCCCGCCCGCCTGTCCCCGCGGCGATTCCAACCCGCCCTGATC CTTTTAAGAAGTTGGCATTTGGCTTTTTAAAAAGCAATAATACAATTTAAAACCTGGGTCTCTAGAGGTG TTAGGACGTGGTGTTGGGTAGGCGCAGGCAGGGGAAAAGGGAGGCGAGGATGTGTCCGATTCTCCTGGAA TCGTTGACTTGGAAAAACCAGGGCGAATCTCCGCACCCAGCCCTGACTCCCCTGCCGCGGCCGCCCTCGG GTGTCCTCGCGCCCGAGATGCGGAGGAACTGCGAGGAGCGGGGCTCTGGGCGGTTCCAGAACAGCTGCTA CCCTTGGTGGGGTGGCTCCGGGGGAGGTATCGCAGCGGGGTCTCTGGCGCAGTTGCATCTCCGTATTGAG TGCGAAGGGAGGTGCCCCTATTATTATTTGACACCCCCCTTGTATTTATGGAGGGGTGTTAAAGCCCGCG GCTGAGCTCGCCACTCCAGCCGGCGAGAGAAAGAAGAAAAGCTGGCAAAAGGAGTGTTGGACGGGGGCGG TACTGGGGGTGGGGACGGGGGCGGTGGAGAGGGAAGGTTGGGAGGGGCTGCGGTGCCGGCGGGGGTAGGA GAGCGGCTAGGGCGCGAGTGGGAACAGCCGCAGCGGAGGGGCCCCGGCGCGGAGCGGGGTTCACGCAGCC GCTAGCGCCCAGGCGCCTCTCGCCTTCTCCTTCAGGTGGCGCAAAACTTTGTGCCTTGGATTTTGGCAAA TTGTTTTCCTCACCGCCACCTCCCGCGGCTTCTTAAGGGCGCCAGGGCCGATTTCGATTCCTCTGCCGCT GCGGGGCCGACTCCCGGGCTTTGCGCTCCGGGCTCCCGGGGGAGCGGGGGCTCGGCGGGCACCAAGCCGC TGGTTCACTAAGTGCGTCTCCGAGATAGCAGGGGACTGTCCAAAGGGGGTGAAAGGGTGCTCCCTTTATT CCCCCACCAAGACCACCCAGCCGCTTTAGGGGATAGCTCTGCAAGGGGAGAGGTTCGGGACTGTGGCGCG CACTGCGCGCTGCGCCAGGTTTCCGCACCAAGACCCCTTTAACTCAAGACTGCCTCCCGCTTTGTGTGCC CCGCTCCAGCAGCCTCCCGCGACGATGCCCCTCAACGTTAGCTTCACCAACAGGAACTATGACCTCGACT ACGACTCGGTGCAGCCGTATTTCTACTGCGACGAGGAGGAGAACTTCTACCAGCAGCAGCAGCAGAGCGA GCTGCAGCCCCCGGCGCCCAGCGAGGATATCTGGAAGAAATTCGAGCTGCTGCCCACCCCGCCCCTGTCC CCTAGCCGCCGCTCCGGGCTCTGCTCGCCCTCCTACGTTGCGGTCACACCCTTCTCCCTTCGGGGAGACA ACGACGGCGGTGGCGGGAGCTTCTCCACGGCCGACCAGCTGGAGATGGTGACCGAGCTGCTGGGAGGAGA CATGGTGAACCAGAGTTTCATCTGCGACCCGGACGACGAGACCTTCATCAAAAACATCATCATCCAGGAC TGTATGTGGAGCGGCTTCTCGGCCGCCGCCAAGCTCGTCTCAGAGAAGCTGGCCTCCTACCAGGCTGCGC GCAAAGACAGCGGCAGCCCGAACCCCGCCCGCGGCCACAGCGTCTGCTCCACCTCCAGCTTGTACCTGCA GGATCTGAGCGCCGCCGCCTCAGAGTGCATCGACCCCTCGGTGGTCTTCCCCTACCCTCTCAACGACAGC AGCTCGCCCAAGTCCTGCGCCTCGCAAGACTCCAGCGCCTTCTCTCCGTCCTCGGATTCTCTGCTCTCCT CGACGGAGTCCTCCCCGCAGGGCAGCCCCGAGCCCCTGGTGCTCCATGAGGAGACACCGCCCACCACCAG CAGCGACTCTGGTAAGCGAAGCCCGCCCAGGCCTGTCAAAAGTGGGCGGCTGGATACCTTTCCCATTTTC ATTGGCAGCTTATTTAACGGGCCACTCTTATTAGGAAGGAGAGATAGCAGATCTGGAGAGATTTGGGAGC TCATCACCTCTGAAACCTTGGGCTTTAGCGTTTCCTCCCATCCCTTCCCCTTAGACTGCCCATGTTTGCA GCCCCCCTCCCCGTTTGTCTCCCACCCCTCAGGAATTTCATTTAGGTTTTTAAACCTTCTGGCTTATCTT ACAACTCAATCCACTTCTTCTTACCTCCCGTTAACATTTTAATTGCCCTGGGGCGGGGTGGCAGGGAGTG TATGAATGAGGATAAGAGAGGATTGATCTCTGAGAGTGAATGAATTGCTTCCCTCTTAACTTCCGAGAAG TGGTGGGATTTAATGAACTATCTACAAAAATGAGGGGCTGTGTTTAGAGGCTAGGCAGGGCCTGCCTGAG TGCGGGAGCCAGTGAACTGCCTCAAGAGTGGGTGGGCTGAGGAGCTGGGATCTTCTCAGCCTATTTTGAA CACTGAAAAGCAAATCCTTGCCAAAGTTGGACTTTTTTTTTTCTTTTATTCCTTCCCCCGCCCTCTTGGA CTTTTGGCAAAACTGCAATTTTTTTTTTTTTATTTTTCATTTCCAGTAAAATAGGGAGTTGCTAAAGTCA TACCAAGCAATTTGCAGCTATCATTTGCAACACCTGAAGTGTTCTTGGTAAAGTCCCTCAAAAATAGGAG GTGCTTGGGAATGTGCTTTGCTTTGGGTGTGTCCAAAGCCTCATTAAGTCTTAGGTAAGAATTGGCATCA ATGTCCTATCCTGGGAAGTTGCACTTTTCTTGTCCATGCCATAACCCAGCTGTCTTTCCCTTTATGAGAC TCTTACCTTCATGGTGAGAGGAGTAAGGGTGGCTGGCTAGATTGGTTCTTTTTTTTTTTTTTTCCTTTTT TAAGACGGAGTCTCACTCTGTCACTAGGCTGGAGTGCAGTGGCGCAATCAACCTCCAACCCCCTGGTTCA AGAGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGACTACAGGTGCACACCACCATGCCAGGCTAATTT TTGTAATTTTAGTAGAGATGGGGTTTCATCGTGTTGGCCAGGATGGTCTCTCCTGACCTCACGATCCGCC CACCTCGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCAGGGCACCAGGCTTAGATGTGGCTCTTTG GGGAGATAATTTTGTCCAGAGACCTTTCTAACGTATTCATGCCTTGTATTTGTACAGCATTAATCTGGTA ATTGATTATTTTAATGTAACCTTGCTAAAGGAGTGATTTCTATTTCCTTTCTTAAAGAGGAGGAACAAGA AGATGAGGAAGAAATCGATGTTGTTTCTGTGGAAAAGAGGCAGGCTCCTGGCAAAAGGTCAGAGTCTGGA TCACCTTCTGCTGGAGGCCACAGCAAACCTCCTCACAGCCCACTGGTCCTCAAGAGGTGCCACGTCTCCA CACATCAGCACAACTACGCAGCGCCTCCCTCCACTCGGAAGGACTATCCTGCTGCCAAGAGGGTCAAGTT GGACAGTGTCAGAGTCCTGAGACAGATCAGCAACAACCGAAAATGCACCAGCCCCAGGTCCTCGGACACC GAGGAGAATGTCAAGAGGCGAACACACAACGTCTTGGAGCGCCAGAGGAGGAACGAGCTAAAACGGAGCT TTTTTGCCCTGCGTGACCAGATCCCGGAGTTGGAAAACAATGAAAAGGCCCCCAAGGTAGTTATCCTTAA AAAAGCCACAGCATACATCCTGTCCGTCCAAGCAGAGGAGCAAAAGCTCATTTCTGAAGAGGACTTGTTG CGGAAACGACGAGAACAGTTGAAACACAAACTTGAACAGCTACGGAACTCTTGTGCGTAAGGAAAAGTAA GGAAAACGATTCCTTCTAACAGAAATGTCCTGAGCAATCACCTATGAACTTGTTTCAAATGCATGATCAA ATGCAACCTCACAACCTTGGCTGAGTCTTGAGACTGAAAGATTTAGCCATAATGTAAACTGCCTCAAATT GGACTTTGGGCATAAAAGAACTTTTTTATGCTTACCATCTTTTTTTTTTCTTTAACAGATTTGTATTTAA GAATTGTTTTTAAAAAATTTTAAGATTTACACAATGTTTCTCTGTAAATATTGCCATTAAATGTAAATAA CTTTAATAAAACGTTTATAGCAGTTACACAGAATTTCAATCCTAGTATATAGTACCTAGTATTATAGGTA CTATAAACCCTAATTTTTTTTATTTAAGTACATTTTGCTTTTTAAAGTTGATTTTTTTCTATTGTTTTTA GAAAAAATAAAATAACTGGCAAATATATCATTGAGCCAAATCTTAA Download Select all
Length	5366
OMIM ID	190080
HGNC ID	HGNC:7553
Unigene ID	Hs.202453
Ensembl ID	ENSG00000136997
PharmGKB ID	-

mRNA Information

mRNA ID	NM_002467.4
Exon	join(526..555,2180..2951,4328..4890)
mRNA Sequence	>4609 GACCCCCGAGCTGTGCTGCTCGCGGCCGCCACCGCCGGGCCCCGGCCGTCCCTGGCTCCCCTCC TGCCTCGAGAAGGGCAGGGCTTCTCAGAGGCTTGGCGGGAAAAAGAACGGAGGGAGGGATCGCG CTGAGTATAAAAGCCGGTTTTCGGGGCTTTATCTAACTCGCTGTAGTAATTCCAGCGAGAGGCA GAGGGAGCGAGCGGGCGGCCGGCTAGGGTGGAAGAGCCGGGCGAGCAGAGCTGCGCTGCGGGCG TCCTGGGAAGGGAGATCCGGAGCGAATAGGGGGCTTCGCCTCTGGCCCAGCCCTCCCGCTGATC CCCCAGCCAGCGGTCCGCAACCCTTGCCGCATCCACGAAACTTTGCCCATAGCAGCGGGCGGGC ACTTTGCACTGGAACTTACAACACCCGAGCAAGGACGCGACTCTCCCGACGCGGGGAGGCTATT CTGCCCATTTGGGGACACTTCCCCGCCGCTGCCAGGACCCGCTTCTCTGAAAGGCTCTCCTTGC AGCTGCTTAGACGCTGGATTTTTTTCGGGTAGTGGAAAACCAGCAGCCTCCCGCGACGATGCCC CTCAACGTTAGCTTCACCAACAGGAACTATGACCTCGACTACGACTCGGTGCAGCCGTATTTCT ACTGCGACGAGGAGGAGAACTTCTACCAGCAGCAGCAGCAGAGCGAGCTGCAGCCCCCGGCGCC CAGCGAGGATATCTGGAAGAAATTCGAGCTGCTGCCCACCCCGCCCCTGTCCCCTAGCCGCCGC TCCGGGCTCTGCTCGCCCTCCTACGTTGCGGTCACACCCTTCTCCCTTCGGGGAGACAACGACG GCGGTGGCGGGAGCTTCTCCACGGCCGACCAGCTGGAGATGGTGACCGAGCTGCTGGGAGGAGA CATGGTGAACCAGAGTTTCATCTGCGACCCGGACGACGAGACCTTCATCAAAAACATCATCATC CAGGACTGTATGTGGAGCGGCTTCTCGGCCGCCGCCAAGCTCGTCTCAGAGAAGCTGGCCTCCT ACCAGGCTGCGCGCAAAGACAGCGGCAGCCCGAACCCCGCCCGCGGCCACAGCGTCTGCTCCAC CTCCAGCTTGTACCTGCAGGATCTGAGCGCCGCCGCCTCAGAGTGCATCGACCCCTCGGTGGTC TTCCCCTACCCTCTCAACGACAGCAGCTCGCCCAAGTCCTGCGCCTCGCAAGACTCCAGCGCCT TCTCTCCGTCCTCGGATTCTCTGCTCTCCTCGACGGAGTCCTCCCCGCAGGGCAGCCCCGAGCC CCTGGTGCTCCATGAGGAGACACCGCCCACCACCAGCAGCGACTCTGAGGAGGAACAAGAAGAT GAGGAAGAAATCGATGTTGTTTCTGTGGAAAAGAGGCAGGCTCCTGGCAAAAGGTCAGAGTCTG GATCACCTTCTGCTGGAGGCCACAGCAAACCTCCTCACAGCCCACTGGTCCTCAAGAGGTGCCA CGTCTCCACACATCAGCACAACTACGCAGCGCCTCCCTCCACTCGGAAGGACTATCCTGCTGCC AAGAGGGTCAAGTTGGACAGTGTCAGAGTCCTGAGACAGATCAGCAACAACCGAAAATGCACCA GCCCCAGGTCCTCGGACACCGAGGAGAATGTCAAGAGGCGAACACACAACGTCTTGGAGCGCCA GAGGAGGAACGAGCTAAAACGGAGCTTTTTTGCCCTGCGTGACCAGATCCCGGAGTTGGAAAAC AATGAAAAGGCCCCCAAGGTAGTTATCCTTAAAAAAGCCACAGCATACATCCTGTCCGTCCAAG CAGAGGAGCAAAAGCTCATTTCTGAAGAGGACTTGTTGCGGAAACGACGAGAACAGTTGAAACA CAAACTTGAACAGCTACGGAACTCTTGTGCGTAAGGAAAAGTAAGGAAAACGATTCCTTCTAAC AGAAATGTCCTGAGCAATCACCTATGAACTTGTTTCAAATGCATGATCAAATGCAACCTCACAA CCTTGGCTGAGTCTTGAGACTGAAAGATTTAGCCATAATGTAAACTGCCTCAAATTGGACTTTG GGCATAAAAGAACTTTTTTATGCTTACCATCTTTTTTTTTTCTTTAACAGATTTGTATTTAAGA ATTGTTTTTAAAAAATTTTAAGATTTACACAATGTTTCTCTGTAAATATTGCCATTAAATGTAA ATAACTTTAATAAAACGTTTATAGCAGTTACACAGAATTTCAATCCTAGTATATAGTACCTAGT ATTATAGGTACTATAAACCCTAATTTTTTTTATTTAAGTACATTTTGCTTTTTAAAGTTGATTT TTTTCTATTGTTTTTAGAAAAAATAAAATAACTGGCAAATATATCATTGAGCCAAATCTTAAAA AAAAAAAAAAA Download Select all
Length	2379

CDS Information

Location	join(1..555,2180..2951,4328..5366)
CDS Sequence	>lcl\|NM_002467.4_cds_NP_002458.2_1 [gene=MYC] [protein=myc proto-oncogene protein] [protein_id=NP_002458.2] [location=526..1890] CTGGATTTTTTTCGGGTAGTGGAAAACCAGCAGCCTCCCGCGACGATGCCCCTCAACGTTAGCTTCACCA ACAGGAACTATGACCTCGACTACGACTCGGTGCAGCCGTATTTCTACTGCGACGAGGAGGAGAACTTCTA CCAGCAGCAGCAGCAGAGCGAGCTGCAGCCCCCGGCGCCCAGCGAGGATATCTGGAAGAAATTCGAGCTG CTGCCCACCCCGCCCCTGTCCCCTAGCCGCCGCTCCGGGCTCTGCTCGCCCTCCTACGTTGCGGTCACAC CCTTCTCCCTTCGGGGAGACAACGACGGCGGTGGCGGGAGCTTCTCCACGGCCGACCAGCTGGAGATGGT GACCGAGCTGCTGGGAGGAGACATGGTGAACCAGAGTTTCATCTGCGACCCGGACGACGAGACCTTCATC AAAAACATCATCATCCAGGACTGTATGTGGAGCGGCTTCTCGGCCGCCGCCAAGCTCGTCTCAGAGAAGC TGGCCTCCTACCAGGCTGCGCGCAAAGACAGCGGCAGCCCGAACCCCGCCCGCGGCCACAGCGTCTGCTC CACCTCCAGCTTGTACCTGCAGGATCTGAGCGCCGCCGCCTCAGAGTGCATCGACCCCTCGGTGGTCTTC CCCTACCCTCTCAACGACAGCAGCTCGCCCAAGTCCTGCGCCTCGCAAGACTCCAGCGCCTTCTCTCCGT CCTCGGATTCTCTGCTCTCCTCGACGGAGTCCTCCCCGCAGGGCAGCCCCGAGCCCCTGGTGCTCCATGA GGAGACACCGCCCACCACCAGCAGCGACTCTGAGGAGGAACAAGAAGATGAGGAAGAAATCGATGTTGTT TCTGTGGAAAAGAGGCAGGCTCCTGGCAAAAGGTCAGAGTCTGGATCACCTTCTGCTGGAGGCCACAGCA AACCTCCTCACAGCCCACTGGTCCTCAAGAGGTGCCACGTCTCCACACATCAGCACAACTACGCAGCGCC TCCCTCCACTCGGAAGGACTATCCTGCTGCCAAGAGGGTCAAGTTGGACAGTGTCAGAGTCCTGAGACAG ATCAGCAACAACCGAAAATGCACCAGCCCCAGGTCCTCGGACACCGAGGAGAATGTCAAGAGGCGAACAC ACAACGTCTTGGAGCGCCAGAGGAGGAACGAGCTAAAACGGAGCTTTTTTGCCCTGCGTGACCAGATCCC GGAGTTGGAAAACAATGAAAAGGCCCCCAAGGTAGTTATCCTTAAAAAAGCCACAGCATACATCCTGTCC GTCCAAGCAGAGGAGCAAAAGCTCATTTCTGAAGAGGACTTGTTGCGGAAACGACGAGAACAGTTGAAAC ACAAACTTGAACAGCTACGGAACTCTTGTGCGTAA Download Select all
CCDS ID	CCDS6359.2

Protein Information

Protein ID	NP_002458.2
Protein Name	v-myc avian myelocytomatosis viral oncogene homolog
Molecular Wt. (Da)	50434
Protein Sequence	>4609 MDFFRVVENQQPPATMPLNVSFTNRNYDLDYDSVQPYFYCDEEENFYQQQQQSELQPPAPSEDI WKKFELLPTPPLSPSRRSGLCSPSYVAVTPFSLRGDNDGGGGSFSTADQLEMVTELLGGDMVNQ SFICDPDDETFIKNIIIQDCMWSGFSAAAKLVSEKLASYQAARKDSGSPNPARGHSVCSTSSLY LQDLSAAASECIDPSVVFPYPLNDSSSPKSCASQDSSAFSPSSDSLLSSTESSPQGSPEPLVLH EETPPTTSSDSEEEQEDEEEIDVVSVEKRQAPGKRSESGSPSAGGHSKPPHSPLVLKRCHVSTH QHNYAAPPSTRKDYPAAKRVKLDSVRVLRQISNNRKCTSPRSSDTEENVKRRTHNVLERQRRNE LKRSFFALRDQIPELENNEKAPKVVILKKATAYILSVQAEEQKLISEEDLLRKRREQLKHKLEQ LRNSCA Download Select all
Length	454
Uniprot ID	P26583
Ensembl Protein ID	ENSP00000296503

Post-translational Modification Information (Source : HPRD)

Residue	Type	site
T	Glycosylation	73
S	Phosphorylation	77
S	Phosphorylation	86
T	Phosphorylation	73
T	Phosphorylation	73
T	Phosphorylation	73
S	Phosphorylation	359
S	Phosphorylation	363
T	Phosphorylation	365
K	Acetylation	163
S	Phosphorylation	21
S	Phosphorylation	79
S	Phosphorylation	88
S	Phosphorylation	176

Enzyme Information

No matching records could be found.

PPi Information

(Click to view network : Source STRING) View

Interactant Gene ID (Source: HPRD)	Gene Symbol	HPRD ID	Ref Seq ID	Technique	References
672	BRCA1	218	NP_009231.2	in vitro;in vivo;yeast 2-hybrid	978 843 712 646 176
983	CDK1	302	NP_001777.1	in vivo	1748630
1050	CEBPA	296	NP_004355.2	in vitro;in vivo	12873812
1051	CEBPB	1801	NP_005185.2	in vitro;in vivo	12873812
1387	CREBBP	2534	NP_004371.2	in vitro;in vivo;yeast 2-hybrid	12776737
1999	ELF3	3722	NP_004424.3	in vitro;in vivo	1651323
2033	EP300	4078	NP_001420.2	in vivo	1 277 673 717 157 250
2932	GSK3B	5418	NP_002084.2	in vitro;in vivo	11 877 389 824 752 400 000 000
2962	GTF2F1	1803	NP_002087.2	in vitro	8755740
3320	HSP90AA1	777	NP_001017963.2	in vivo	12644583
4149	MAX	1113	NP_002373.3	in vitro;in vivo	2 006 410 170 723 080 000 000 000 000 000 000 000 000 000 000
4292	MLH1	390	NP_000240.1	in vitro;in vivo;yeast 2-hybrid	12584560
4801	NFYB	1794	NP_006157.1	in vitro;in vivo	11282029
5371	PML	23	NP_150241.2	in vitro;in vivo	15735755
5604	MAP2K1	1469	NP_002746.1	in vitro	7957875
5894	RAF1	1265	NP_002871.1	in vitro	9315742
5925	RB1	1574	NP_000312.2	in vivo	7838535
5933	RBL1	312	NP_002886.2	in vivo	8076603
5970	RELA	1241	NP_068810.3	in vivo	12027803
6502	SKP2	3256	NP_005974.2	in vivo	17157259
6667	SP1	1796	NP_612482.2	in vivo	11274368
6908	TBP	2511	NP_003185.1	in vivo	15723054
9014	TAF1B	5363	NP_005671.2	in vivo	15723054
57650	KIAA1524	11151	NP_065941.2	in vitro;in vivo	1 947 095 417 632 050
84875	PARP10	15100	NP_116178.2	in vitro;in vivo	15674325

Pathway Information

Pathway Name	Pathway ID
Acute myeloid leukemia	hsa05221
Bladder cancer	hsa05219
Cell cycle	hsa04110
Central carbon metabolism in cancer	hsa05230
Chronic myeloid leukemia	hsa05220
Colorectal cancer	hsa05210
Endometrial cancer	hsa05213
Epstein-Barr virus infection	hsa05169
ErbB signaling pathway	hsa04012
Hepatitis B	hsa05161
Hippo signaling pathway	hsa04390
HTLV-I infection	hsa05166
Jak-STAT signaling pathway	hsa04630
MAPK signaling pathway	hsa04010
MicroRNAs in cancer	hsa05206
Pathways in cancer	hsa05200
PI3K-Akt signaling pathway	hsa04151
Proteoglycans in cancer	hsa05205
Signaling pathways regulating pluripotency of stem cells	hsa04550
Small cell lung cancer	hsa05222
TGF-beta signaling pathway	hsa04350
Thyroid cancer	hsa05216
Thyroid hormone signaling pathway	hsa04919
Transcriptional misregulation in cancer	hsa05202
Wnt signaling pathway	hsa04310

Structure Information

PDB ID	1A93
Resolution
Method	SOLUTION NMR
Chains	A
Molecule	MYC PROTO-ONCOGENE PROTEIN
Model	View

Domain Information

ID	Location	Description
cd00083	355-411	HLH
cl00081	355-411	HLH superfamily
pfam01056	1-345	Myc_N
cl03082	1-345	Myc_N superfamily
smart00353	360-412	HLH
pfam00010	355-407	HLH
pfam02344	408-439	Myc-LZ
cl03551	408-439	Myc-LZ superfamily

Ontology Information

HPRD ID	2612
Molecular Class	Transcription factor
Molecular Function	Transcription regulator activity (GO:0030528)
Biological Process	Regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0019219)

SNP Information

View SNP Geneview Report

CoReCG

Search results:

General Information

Evidence Information

Gene Details

mRNA Information

CDS Information

Protein Information

Post-translational Modification Information (Source : HPRD)

Enzyme Information

PPi Information

Pathway Information

Structure Information

Domain Information

Ontology Information

SNP Information

Drug Information

External Links

Important Information

ArrayExpress	GO
ICGC	GO
Cancer3D	GO
COSMIC	GO
NCG	GO
TSGene	GO
Tumor Gene Family of Databases	GO
CCDB	GO
G2SBC	GO
Osteosarcoma Database	GO
RCDB	GO