Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| LAPTM4B | 55353 | lysosomal protein transmembrane 4 beta  | 8 | LC27  |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 22578410    | 2012 | Cell line : - Source : Tumor Hospital of Harbin Medical University, Harbin, China Sample Type : CRC tumor and normal tissue No. of Sample : 161 Stage : - | Immunohistochemistry, Western blotting | Up-regulation | - | LAPTM4B overexpression is an independent factor in colorectal cancer prognosis, and it may be an important potential biomarker. Among the 136 patients with colorectal cancer, 51 patients had low LAPTM4B expression, and 85 patients had high LAPTM4B expression. The sensitivity and specificity of LAPTM4B overexpression were 62.5% and 100%, respectively. |
Gene Details

| Gene Type | protein coding |
|---|---|
| Gene Family | |
| Description | -   |
| Chromosome | 8 |
| Location | 8q22.1 |
| Start | 97775581   |
| End | 97852602   |
| Strand | +   |
| Gene Sequence |    Download   Select all |
| Length | 77022   |
| OMIM ID | 613296    |
| HGNC ID | HGNC:13646    |
| Unigene ID | Hs.492314    |
| Ensembl ID | ENSG00000104341    |
| PharmGKB ID | -    |
mRNA Information
| mRNA ID | NM_018407.4 |
|---|---|
| Exon | join(1..528,29773..29884,39748..39821,40478..40600, 43560..43658,49478..49573,75817..77022)   | mRNA Sequence |    Download   Select all |
| Length | 2242   |
CDS Information
| Location | join(157..528,29773..29884,39748..39821,40478..40600, 43560..43658,49478..49573,75817..75894) |
|---|---|
| CDS Sequence |    Download   Select all |
| CCDS ID | CCDS6275.1 |    
Protein Information
| Protein ID | NP_060877.3 |
|---|---|
| Protein Name | lysosomal protein transmembrane 4 beta |
| Molecular Wt. (Da) | 34992 |
| Protein Sequence |    Download   Select all |
| Length | 317   |
| Uniprot ID | P55268 |    
| Ensembl Protein ID | ENSP00000307156   |    
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING)      View   
No matching records from HPRD source could be found.
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Lysosome |    hsa04142 |    
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| pfam03821 | 164-370  | Mtp |
| cl04276 | 164-370  | Mtp superfamily |
| TIGR00799 | 153-370  | mtp |
Ontology Information
| HPRD ID | 1032 |    
|---|---|
| Molecular Class | Unclassified |
| Molecular Function | Extracellular matrix structural constituent (GO:0005201) |
| Biological Process | Cell growth and/or maintenance (GO:0008151)   |
Drug Information
No matching records could be found.
External Links
| ArrayExpress | GO |    
|---|---|
| ICGC | GO |    
| Cancer3D | GO |    
| COSMIC | GO |    
| NCG | GO |    
| TSGene | GO |    
| Tumor Gene Family of Databases | GO |    
| CCDB | GO |    
| G2SBC | GO |    
| Osteosarcoma Database | GO |    
| RCDB | GO |    
