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General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
KLF9 687 Kruppel-like factor 9  9- 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
18477211   2008Cell line : -

Source : -

Sample Type : CRC tumor and normal tissues

No. of Sample : 50

Stage : -

real time RT-PCR,western blotting.Down-regulation-KLF9 may be involved in the carcinogenesis of human colorectal cancer.


Gene Details



NC_000009.11 (72999513..73029573, complement)

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Gene Type protein coding
Gene Family Kruppel-like transcription factors, "Zinc fingers, C2H2-type"
Description The protein encoded by this gene is a transcription factor that binds to GC box elements located in the promoter. Binding of the encoded protein to a single GC box inhibits mRNA expression while binding to tandemly repeated GC box elements activates transcription. [provided by RefSeq, Jul 2008]  
Chromosome 9
Location 9q21.11
Start 72999513  
End 73029573  
Strand -  
Gene Sequence

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Length 30061  
OMIM ID 602902   
HGNC ID HGNC:1123   
Unigene ID Hs.150557   
Ensembl ID ENSG00000119138   
PharmGKB ID PA25444   

mRNA Information


mRNA ID NM_001206.2
Exon join(1..1799,26653..30061)  
mRNA Sequence

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Length 5208  



CDS Information


   
Location 1295..2029
CDS Sequence

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CCDS ID CCDS6633.1



Protein Information


      
Protein IDNP_001197.1
Protein NameKruppel-like factor 9
Molecular Wt. (Da)27104
Protein Sequence

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Length 244  
Uniprot IDQ9UJ68
Ensembl Protein ID ENSP00000313921  



Post-translational Modification Information (Source : HPRD)


No matching records could be found.

Enzyme Information


No matching records could be found.

PPi Information


(Click to view network : Source STRING)      View   

No matching records from HPRD source could be found.

Pathway Information


No matching records could be found.

Structure Information


No matching records could be found.

Domain Information




ID Location Description
pfam13465189-212  zf-H2C2_2
cl22375189-212  zf-H2C2_2 superfamily
pfam13465159-186  zf-H2C2_2
cl22375159-186  zf-H2C2_2 superfamily
COG504894-234  COG5048
COG518979-226  SFP1
COG5048157-205  COG5048
PHA00733172-221  PHA00733
COG5048145-221  COG5048
COG5236130-229  COG5236
COG5048171-232  COG5048


Ontology Information


   
HPRD ID798
Molecular ClassTranscription factor
Molecular FunctionGrowth factor activity (GO:0008083)
Biological ProcessCell communication (GO:0007154); Signal transduction (GO:0007165)  



SNP Information


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Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO