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General Information
- Evidence
- Gene
- mRNA
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- Protein
- PTM
- Enzyme
- PPi
- Pathway
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- Domain
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Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 18477211 | 2008 | Cell line : - Source : - Sample Type : CRC tumor and normal tissues No. of Sample : 50 Stage : - | real time RT-PCR,western blotting. | Down-regulation | - | KLF9 may be involved in the carcinogenesis of human colorectal cancer. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | Kruppel-like transcription factors, "Zinc fingers, C2H2-type" |
| Description | The protein encoded by this gene is a transcription factor that binds to GC box elements located in the promoter. Binding of the encoded protein to a single GC box inhibits mRNA expression while binding to tandemly repeated GC box elements activates transcription. [provided by RefSeq, Jul 2008] | Chromosome | 9 |
| Location | 9q21.11 |
| Start | 72999513 |
| End | 73029573 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 30061 |
| OMIM ID | 602902 |
| HGNC ID | HGNC:1123 |
| Unigene ID | Hs.150557 |
| Ensembl ID | ENSG00000119138 |
| PharmGKB ID | PA25444 |
mRNA Information
| mRNA ID | NM_001206.2 |
|---|---|
| Exon | join(1..1799,26653..30061) | mRNA Sequence | Download Select all |
| Length | 5208 |
Protein Information
| Protein ID | NP_001197.1 |
|---|---|
| Protein Name | Kruppel-like factor 9 |
| Molecular Wt. (Da) | 27104 |
| Protein Sequence | Download Select all |
| Length | 244 |
| Uniprot ID | Q9UJ68 |
| Ensembl Protein ID | ENSP00000313921 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
No matching records from HPRD source could be found.
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| pfam13465 | 189-212 | zf-H2C2_2 |
| cl22375 | 189-212 | zf-H2C2_2 superfamily |
| pfam13465 | 159-186 | zf-H2C2_2 |
| cl22375 | 159-186 | zf-H2C2_2 superfamily |
| COG5048 | 94-234 | COG5048 |
| COG5189 | 79-226 | SFP1 |
| COG5048 | 157-205 | COG5048 |
| PHA00733 | 172-221 | PHA00733 |
| COG5048 | 145-221 | COG5048 |
| COG5236 | 130-229 | COG5236 |
| COG5048 | 171-232 | COG5048 |
Ontology Information
| HPRD ID | 798 |
|---|---|
| Molecular Class | Transcription factor |
| Molecular Function | Growth factor activity (GO:0008083) |
| Biological Process | Cell communication (GO:0007154); Signal transduction (GO:0007165) |
Drug Information
No matching records could be found.