Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| KHSRP | 8570 | KH-type splicing regulatory protein (FUSE binding protein 2)  | 19 | FBP2; KSRP; FUBP2  |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 20089989    | 2010 | Cell line : - Source : VU University Medical Center, Amsterdam, The Netherlands. Sample Type : CRC tumor and normal tissue No. of Sample : - Stage : - | Biochemical isolation to nano-LC-MS/MS analysis | Down-regulation | - | This genes are differenitially expressed between colorectal adenoma and Colorectal cancer tissue. CRC tissue was collected at the VU University Medical Center, Amsterdam, The Netherlands. |
Gene Details

| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | The KHSRP gene encodes a multifunctional RNA-binding protein implicated in a variety of cellular processes, including transcription, alternative pre-mRNA splicing, and mRNA localization (Min et al., 1997 [PubMed 9136930]; Gherzi et al., 2004 [PubMed 15175153]).[supplied by OMIM, Apr 2010]   |
| Chromosome | 19 |
| Location | 19p13.3 |
| Start | 6413104   |
| End | 6424811   |
| Strand | -   |
| Gene Sequence |    Download   Select all |
| Length | 11708   |
| OMIM ID | 603445    |
| HGNC ID | HGNC:6316    |
| Unigene ID | Hs.727344    |
| Ensembl ID | ENSG00000088247    |
| PharmGKB ID | -    |
mRNA Information
| mRNA ID | NM_003685.2 |
|---|---|
| Exon | join(1..359,2376..2472,3124..3162,3495..3534,4341..4390, 4668..4739,5552..5609,5936..6110,6231..6329,6733..6831, 6971..7073,7725..7825,7930..8074,8162..8322,8405..8514, 8916..9004,9078..9278,9355..9432,9511..9671,10692..11708)   | mRNA Sequence |    Download   Select all |
| Length | 3262   |
CDS Information
| Location | join(111..359,2376..2472,3124..3162,3495..3534,4341..4390, 4668..4739,5552..5609,5936..6110,6231..6329,6733..6831, 6971..7073,7725..7825,7930..8074,8162..8322,8405..8514, 8916..9004,9078..9278,9355..9432,9511..9671,10692..10700) |
|---|---|
| CDS Sequence |    Download   Select all |
| CCDS ID | CCDS45936.1 |    
Protein Information
| Protein ID | NP_003676.2 |
|---|---|
| Protein Name | KH-type splicing regulatory protein (FUSE binding protein 2) |
| Molecular Wt. (Da) | 72984 |
| Protein Sequence |    Download   Select all |
| Length | 711   |
| Uniprot ID | Q92633 |    
| Ensembl Protein ID | ENSP00000351755   |    
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| S | Phosphorylation | 181;- |
| S | Phosphorylation | 132;- |
| S | Phosphorylation | 274;- |
| S | Phosphorylation | 670;- |
| S | Phosphorylation | 274;- |
| S | Phosphorylation | 480;- |
| T | Phosphorylation | 100 |
| S | Phosphorylation | 184 |
| T | Phosphorylation | 277 |
| S | Phosphorylation | 191 |
| S | Acetylation | 2 |
| K | Acetylation | 87 |
| S | Phosphorylation | 174 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING)      View   
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 5073 |    PARN |    7250 |    NP_002573.1 |    in vitro;in vivo |    15175153    |
| 23404 |    EXOSC2 |    3758 |    NP_055100.2 |    in vitro;in vivo |    15175153    |
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd00105 | 146-208  | KH-I |
| cl00098 | 146-208  | KH-I superfamily |
| cd00105 | 325-386  | KH-I |
| cl00098 | 325-386  | KH-I superfamily |
| cd00105 | 426-492  | KH-I |
| cl00098 | 426-492  | KH-I superfamily |
| cd00105 | 235-300  | KH-I |
| cl00098 | 235-300  | KH-I superfamily |
| smart00322 | 143-212  | KH |
| pfam00013 | 146-208  | KH_1 |
| smart00322 | 426-495  | KH |
| cd02396 | 151-204  | PCBP_like_KH |
| smart00322 | 234-303  | KH |
| pfam00013 | 426-491  | KH_1 |
| smart00322 | 325-390  | KH |
| pfam00013 | 235-299  | KH_1 |
| pfam00013 | 327-386  | KH_1 |
| pfam13014 | 155-196  | KH_3 |
| cd02396 | 238-299  | PCBP_like_KH |
| cd02394 | 146-208  | vigilin_like_KH |
| cd02396 | 431-469  | PCBP_like_KH |
| pfam13014 | 334-374  | KH_3 |
| cd02396 | 329-386  | PCBP_like_KH |
| pfam13014 | 244-287  | KH_3 |
| cd02394 | 426-492  | vigilin_like_KH |
| pfam13014 | 435-479  | KH_3 |
| cd02394 | 325-382  | vigilin_like_KH |
| cd02393 | 141-209  | PNPase_KH |
| cd02393 | 238-286  | PNPase_KH |
| cd02393 | 428-492  | PNPase_KH |
| cd02394 | 237-300  | vigilin_like_KH |
| pfam09005 | 671-689  | DUF1897 |
| cl07567 | 671-689  | DUF1897 superfamily |
| pfam07650 | 237-267  | KH_2 |
| cd02411 | 232-262  | archeal_30S_S3_KH |
| COG1094 | 238-390  | Krr1 |
| PRK13763 | 145-301  | PRK13763 |
| PRK11824 | 238-305  | PRK11824 |
| PRK11824 | 141-248  | PRK11824 |
| TIGR03665 | 237-391  | arCOG04150 |
| PRK13763 | 234-391  | PRK13763 |
| COG1185 | 152-248  | Pnp |
| COG1185 | 428-493  | Pnp |
| TIGR03591 | 238-305  | polynuc_phos |
| TIGR03591 | 141-213  | polynuc_phos |
| PRK11824 | 428-493  | PRK11824 |
| COG1185 | 238-305  | Pnp |
| TIGR03591 | 428-493  | polynuc_phos |
| PRK08406 | 240-274  | PRK08406 |
| TIGR02696 | 316-364  | pppGpp_PNP |
Ontology Information
| HPRD ID | 8834 |    
|---|---|
| Molecular Class | Transcription regulatory protein |
| Molecular Function | G-protein coupled receptor activity (GO:0004930) |
| Biological Process | Cell communication (GO:0007154); Signal transduction (GO:0007165)   |
Drug Information
No matching records could be found.
External Links
| ArrayExpress | GO |    
|---|---|
| ICGC | GO |    
| Cancer3D | GO |    
| COSMIC | GO |    
| NCG | GO |    
| TSGene | GO |    
| Tumor Gene Family of Databases | GO |    
| CCDB | GO |    
| G2SBC | GO |    
| Osteosarcoma Database | GO |    
| RCDB | GO |    
