Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| ADIPOQ | 9370 | Adiponectin, C1Q and collagen domain containing  | 3 | ACDC; ADPN; APM1; APM-1; GBP28; ACRP30; ADIPQTL1  |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 20331631    | 2010 | Cell line : - Source : Memorial Sloan-Kettering Cancer, New York, Northwestern University in Chicago, Illinois. Sample Type : Blood sample No. of Sample : 441 CRC patients and 658 healthy volunteers and Case control study of 199 matched pairs of colorectal cancer cases and controls Stage : TNM Stage I-IV | - | Down-regulation | - | Adiponectin level may be a good biomarker of colorectal adenoma. The adiponectin level in adenoma patients was significantly lower than that of controls on multivariate analysis (P = 0.04). |
| 18827209    | 2008 | Cell line : - Source : - Sample Type : - No. of Sample : 115 colorectal cancer patients Stage : - | Genotyping | Polymorhpism | - | The SNP rs266729, which tags the 5' flanking region of the ADIPOQ gene, is associated with decreased colorectal cancer risk. |
Gene Details

| Gene Type | protein coding |
|---|---|
| Gene Family | Endogenous ligands |
| Description | This gene is expressed in adipose tissue exclusively. It encodes a protein with similarity to collagens X and VIII and complement factor C1q. The encoded protein circulates in the plasma and is involved with metabolic and hormonal processes. Mutations in this gene are associated with adiponectin deficiency. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Apr 2010]   |
| Chromosome | 3 |
| Location | 3q27 |
| Start | 186842668   |
| End | 186858463   |
| Strand | +   |
| Gene Sequence |    Download   Select all |
| Length | 15796   |
| OMIM ID | 605441    |
| HGNC ID | HGNC:13633    |
| Unigene ID | Hs.80485     |
| Ensembl ID | ENSG00000181092    |
| PharmGKB ID | -    |
mRNA Information
| mRNA ID | XM_011513324.1 |
|---|---|
| Exon | join(1..82,8439..8554,10384..10605,11517..15251)   | mRNA Sequence |    Download   Select all |
| Length | 4155   |
CDS Information
| Location | join(10392..10605,11517..12037) |
|---|---|
| CDS Sequence |    Download   Select all |
| CCDS ID | CCDS3284.1 |    
Protein Information
| Protein ID | NP_001171271.1 |
|---|---|
| Protein Name | Adiponectin, C1Q and collagen domain containing |
| Molecular Wt. (Da) | 24982 |
| Protein Sequence |    Download   Select all |
| Length | 244   |
| Uniprot ID | P06733 |    
| Ensembl Protein ID | ENSP00000234590   |    
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| K | Glycosylation | 101 |
| K | Hydroxylation | 101 |
| K | Glycosylation | 65 |
| K | Hydroxylation | 65 |
| K | Glycosylation | 68 |
| K | Hydroxylation | 68 |
| K | Glycosylation | 77 |
| K | Hydroxylation | 77 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING)      View   
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 1012 |    CDH13 |    3219 |    NP_001248.1 |    in vivo |    15210937    |
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Adipocytokine signaling pathway |    hsa04920 |    
| AMPK signaling pathway |    hsa04152 |    
| Longevity regulating pathway - mammal |    hsa04211 |    
| Non-alcoholic fatty liver disease (NAFLD) |    hsa04932 |    
| PPAR signaling pathway |    hsa03320 |    
| Type II diabetes mellitus |    hsa04930 |    
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| smart00110 | 106-242  | C1Q |
| cl00147 | 106-242  | TNF superfamily |
| pfam00386 | 114-239  | C1q |
| pfam01391 | 42-106  | Collagen |
| cl22949 | 42-106  | Collagen superfamily |
| pfam01391 | 40-92  | Collagen |
Ontology Information
| HPRD ID | 1555 |    
|---|---|
| Molecular Class | Secreted polypeptide |
| Molecular Function | Transmembrane receptor protein tyrosine kinase activity (GO:0004714) |
| Biological Process | Cell communication (GO:0007154); Signal transduction (GO:0007165)   |
Drug Information
No matching records could be found.
External Links
| ArrayExpress | GO |    
|---|---|
| ICGC | GO |    
| Cancer3D | GO |    
| COSMIC | GO |    
| NCG | GO |    
| TSGene | GO |    
| Tumor Gene Family of Databases | GO |    
| CCDB | GO |    
| G2SBC | GO |    
| Osteosarcoma Database | GO |    
| RCDB | GO |    
