Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| BCL6B | 255877 | B-cell CLL/lymphoma 6, member B | 17 | ZBTB28, BAZF |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 25973304 | 2015 | Cell line : - Source : Chinese PLA General Hospital. Sample Type : CRC tumor and normal tissue No. of Sample : 102 Stage : TNM Stage I-IV | real time RT-PCR,Bisulfite modification, methylation specific PCR and bisulfite sequencing ,Immunohistochemistry,Flow cytometry,Cell viability assay | Methylation | - | �Methylation of�BCL6B�is a prognostic and chemo-sensitive marker in�colorectal cancer.�BCL6B�suppresses�colorectal cancer�growth by activating P53 signaling. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | -, "Zinc fingers, C2H2-type", "BTB/POZ domain containing" |
| Description | - | Chromosome | 17 |
| Location | 17p13.1 |
| Start | 6926368 |
| End | 6933609 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 7242 |
| OMIM ID | 608992 |
| HGNC ID | HGNC:1002 |
| Unigene ID | Hs.22575 |
| Ensembl ID | ENSG00000161940 |
| PharmGKB ID | PA25313 |
Protein Information
| Protein ID | NP_862827.1 |
|---|---|
| Protein Name | B-cell CLL/lymphoma 6, member B |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 479 |
| Uniprot ID | Q6UXX9 |
| Ensembl Protein ID | ENSP00000276659 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 604 | BCL6 | 180 | NP_620309.1 | in vitro;in vivo | 9632807 |
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| pfam00651 | 28-134 | BTB |
| cl02518 | 28-134 | BTB superfamily |
| smart00225 | 39-131 | BTB |
| pfam13465 | 370-395 | zf-H2C2_2 |
| cl22375 | 370-395 | zf-H2C2_2 superfamily |
| pfam13465 | 398-423 | zf-H2C2_2 |
| cl22375 | 398-423 | zf-H2C2_2 superfamily |
| pfam13465 | 427-451 | zf-H2C2_2 |
| cl22375 | 427-451 | zf-H2C2_2 superfamily |
| pfam13465 | 342-367 | zf-H2C2_2 |
| cl22375 | 342-367 | zf-H2C2_2 superfamily |
| COG5048 | 354-411 | COG5048 |
| COG5048 | 316-461 | COG5048 |
| COG5189 | 323-430 | SFP1 |
| COG5048 | 410-446 | COG5048 |
| COG5048 | 382-439 | COG5048 |
| COG5048 | 313-383 | COG5048 |
| PHA00733 | 411-463 | PHA00733 |
Ontology Information
| HPRD ID | 17536 |
|---|---|
| Molecular Class | Transcription regulatory protein |
| Molecular Function | Receptor binding (GO:0005102) |
| Biological Process | Signal transduction (GO:0007165) |
Drug Information
No matching records could be found.