Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| CLIC2 | 1193 | Chloride intracellular channel 2  | X | CLIC2b; MRXS32; XAP121  |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 22968445    | 2012 | Cell line : - Source : Department of Pathology of Wrocaw Medical University. Sample Type : - No. of Sample : - Stage : - | Laser capture microdissection,FFPE-FASP,SAX fractionation,LC-MSMS,Label-free quantitation. | Down-regulation | 0.026 | - |
Gene Details

| Gene Type | protein coding |
|---|---|
| Gene Family | Ion channels / Chloride channels : Intracellular |
| Description | Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 2 is a member of the p64 family; the protein is detected in fetal liver and adult skeletal muscle tissue. This gene maps to the candidate region on chromosome X for incontinentia pigmenti. [provided by RefSeq, Jul 2008]   | Chromosome | X |
| Location | Xq28 |
| Start | 155276207   |
| End | 155334681   |
| Strand | -   |
| Gene Sequence |    Download   Select all |
| Length | 58475   |
| OMIM ID | 300138    |
| HGNC ID | HGNC:2063    |
| Unigene ID | Hs.655445     |
| Ensembl ID | ENSG00000155962    |
| PharmGKB ID | -    |
mRNA Information
| mRNA ID | NM_001289.5 |
|---|---|
| Exon | join(1..311,35537..35646,35772..35897,54614..54720, 55352..55533,56618..58475)   | mRNA Sequence |    Download   Select all |
| Length | 2702   |
CDS Information
| Location | join(255..311,35537..35646,35772..35897,54614..54720, 55352..55533,56618..56779) |
|---|---|
| CDS Sequence |    Download   Select all |
| CCDS ID | CCDS14767.1 |    
Protein Information
| Protein ID | NP_001280.3 |
|---|---|
| Protein Name | Chloride intracellular channel 2 |
| Molecular Wt. (Da) | 28225 |
| Protein Sequence |    Download   Select all |
| Length | 247   |
| Uniprot ID | P07288 |    
| Ensembl Protein ID | ENSP00000314151   |    
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING)      View   
No matching records from HPRD source could be found.
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd10298 | 106-244  | GST_C_CLIC2 |
| cl02776 | 106-244  | GST_C_family superfamily |
| cd03061 | Sep-99  | GST_N_CLIC |
| cl00388 | Sep-99  | Thioredoxin_like superfamily |
| cd10297 | 106-245  | GST_C_CLIC5 |
| cd10296 | 106-245  | GST_C_CLIC4 |
| cd10301 | 106-245  | GST_C_CLIC6 |
| cd10300 | 108-244  | GST_C_CLIC1 |
| cd03198 | 106-240  | GST_C_CLIC |
| cd10299 | 106-239  | GST_C_CLIC3 |
| cd03201 | 107-235  | GST_C_DHAR |
| pfam13409 | 30-93  | GST_N_2 |
| cd00570 | 29-91  | GST_N_family |
| pfam13417 | 30-98  | GST_N_3 |
| cd03059 | 29-74  | GST_N_SspA |
| cd00299 | 86-218  | GST_C_family |
| pfam13410 | 169-216  | GST_C_2 |
| cd03177 | 110-200  | GST_C_Delta_Epsilon |
| cd03055 | 30-59  | GST_N_Omega |
| cd03060 | 30-91  | GST_N_Omega_like |
| cd10424 | 176-216  | GST_C_9 |
| cd03190 | 127-229  | GST_C_Omega_like |
| TIGR00862 | 12-245  | O-ClC |
| PLN02817 | 14-232  | PLN02817 |
| PLN02378 | 14-240  | PLN02378 |
| PRK09481 | 43-106  | sspA |
Ontology Information
| HPRD ID | 1461 |    
|---|---|
| Molecular Class | Intracellular ligand gated channel |
| Molecular Function | Serine-type peptidase activity (GO:0008236) |
| Biological Process | Proteolysis and peptidolysis (GO:0006508); Immune response (GO:0006955)   |
Drug Information
No matching records could be found.
External Links
| ArrayExpress | GO |    
|---|---|
| ICGC | GO |    
| Cancer3D | GO |    
| COSMIC | GO |    
| NCG | GO |    
| TSGene | GO |    
| Tumor Gene Family of Databases | GO |    
| CCDB | GO |    
| G2SBC | GO |    
| Osteosarcoma Database | GO |    
| RCDB | GO |    
