Search results:
General Information
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 21331762    | 2011 | Cell line : - Source : - Sample Type : - No. of Sample : 12 CRC patients Stage : - | Real-time RT-PCR and DNA sequencing analysis | Up-regulation | - | Results revealed that ST3GAL5, IFITM3, PDAP1, ALKBH3, NUDT14, CNN2, MAPK14, ACO1, and SEPHS1 may be involved in rectal carcinogenesis. |
| 22968445    | 2012 | Cell line : - Source : Department of Pathology of Wroc$aw Medical University. Sample Type : - No. of Sample : - Stage : - | Laser capture microdissection,FFPE-FASP,SAX fractionation,LC-MSMS,Label-free quantitation. | Up-regulation | 8.9 | - |
Gene Details

| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | The protein encoded by this gene, which can bind actin, calmodulin, troponin C, and tropomyosin, may function in the structural organization of actin filaments. The encoded protein could play a role in smooth muscle contraction and cell adhesion. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]   | Chromosome | 19 |
| Location | 19p13.3 |
| Start | 1026275   |
| End | 1039068   |
| Strand | +   |
| Gene Sequence |    Download   Select all |
| Length | 12794   |
| OMIM ID | 602373    |
| HGNC ID | HGNC:2156    |
| Unigene ID | Hs.651512    |
| Ensembl ID | ENSG00000064666    |
| PharmGKB ID | -    |
mRNA Information
| mRNA ID | NM_001303501.1 |
|---|---|
| Exon | join(1..450,4797..4918,6118..6184,6285..6422,9793..9972, 10142..10288,11351..12794)   | mRNA Sequence |    Download   Select all |
| Length | 2478   |
CDS Information
| Location | join(388..450,4797..4918,6118..6184,6285..6422,9793..9972, 10142..10288,11351..11626) |
|---|---|
| CDS Sequence |    Download   Select all |
| CCDS ID | - |    
Protein Information
| Protein ID | NP_004359.1 |
|---|---|
| Protein Name | Calponin 2 |
| Molecular Wt. (Da) | 33566 |
| Protein Sequence |    Download   Select all |
| Length | 309   |
| Uniprot ID | P29972 |    
| Ensembl Protein ID | ENSP00000311165   |    
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| Y | Phosphorylation | 303;- |
| Y | Phosphorylation | 264;- |
| Y | Phosphorylation | 184;- |
| Y | Phosphorylation | 145;- |
| K | Acetylation | 25 |
| K | Acetylation | 25 |
| K | Acetylation | 8 |
| K | Acetylation | 8 |
| T | Phosphorylation | 172 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING)      View   
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 60 |    ACTB |    32 |    NP_001092.1 |    in vivo |    12388067    |
Pathway Information
No matching records could be found.
Structure Information
| PDB ID | 1WYN |
|---|---|
| Resolution | - |
| Method | solution NMR |
| Chains | A   |
| Molecule | Calponin-2   |
| Model | View |
Domain Information
| ID | Location | Description |
|---|---|---|
| cd00014 | 31-131  | CH |
| cl00030 | 31-131  | CH superfamily |
| smart00033 | 33-127  | CH |
| pfam00307 | 31-127  | CH |
| pfam00402 | 166-191  | Calponin |
| cl02859 | 166-191  | Calponin superfamily |
| pfam00402 | 206-231  | Calponin |
| cl02859 | 206-231  | Calponin superfamily |
| pfam00402 | 245-269  | Calponin |
| cl02859 | 245-269  | Calponin superfamily |
| COG5199 | 19-190  | SCP1 |
| COG5261 | 33-136  | IQG1 |
Ontology Information
| HPRD ID | 140 |    
|---|---|
| Molecular Class | Cytoskeletal associated protein |
| Molecular Function | Water channel activity (GO:0015250) |
| Biological Process | Transport (GO:0006810); Ion transport (GO:0006811)   |
Drug Information
No matching records could be found.
External Links
| ArrayExpress | GO |    
|---|---|
| ICGC | GO |    
| Cancer3D | GO |    
| COSMIC | GO |    
| NCG | GO |    
| TSGene | GO |    
| Tumor Gene Family of Databases | GO |    
| CCDB | GO |    
| G2SBC | GO |    
| Osteosarcoma Database | GO |    
| RCDB | GO |    
