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General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
FLT3 2322 fms-related tyrosine kinase 3  13STK1, FLK2, CD135 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
10738251   2000Cell line : -

Source : -

Sample Type : -

No. of Sample : -

Stage : -

real time RT-PCRUnknown--


Gene Details



NC_000013.10 (28577411..28682904, complement)

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Gene Type protein coding
Gene Family CD molecules, "Immunoglobulin superfamily / Immunoglobulin-like domain containing"
Description This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia. [provided by RefSeq, Jan 2015]  
Chromosome 13
Location 13q12
Start 28577411  
End 28682904  
Strand -  
Gene Sequence

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Length 105494  
OMIM ID 136351   
HGNC ID HGNC:3765   
Unigene ID Hs.507590   
Ensembl ID ENSG00000122025   
PharmGKB ID PA28181   

mRNA Information


mRNA ID NM_004119.2
Exon join(1..125,29981..30102,38524..38726,43131..43246, 47919..48048,50371..50498,50819..50958,51056..51209, 52150..52318,63305..63408,64550..64658,64920..65098, 66186..66292,66379..66511,66602..66706,72305..72415, 73352..73505,75650..75732,77116..77243,82004..82126, 84892..85003,85337..85436,86036..86141,96419..97319)  
mRNA Sequence

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Length 3848  



CDS Information


   
Location 83..3064
CDS Sequence

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CCDS ID CCDS31953.1



Protein Information


      
Protein IDNP_004110.2
Protein Namefms-related tyrosine kinase 3
Molecular Wt. (Da)0
Protein Sequence

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Length 993  
Uniprot IDP49792
Ensembl Protein ID ENSP00000283195  



Post-translational Modification Information (Source : HPRD)


Residue Type site
YPhosphorylation589
YPhosphorylation591
YPhosphorylation597
YPhosphorylation599

Enzyme Information


No matching records could be found.

PPi Information


(Click to view network : Source STRING)      View   

               
Interactant Gene ID (Source: HPRD) Gene Symbol HPRD ID Ref Seq ID Technique References
2885GRB2150NP_002077.1in vivo10080542   


Pathway Information


                                    
Pathway Name Pathway ID
Acute myeloid leukemia hsa05221
Central carbon metabolism in cancer hsa05230
Cytokine-cytokine receptor interaction hsa04060
Hematopoietic cell lineage hsa04640
Pathways in cancer hsa05200
Transcriptional misregulation in cancer hsa05202


Structure Information


No matching records could be found.

Domain Information




ID Location Description
cd05055572-947  PTKc_PDGFR
cl21453572-947  PKc_like superfamily
cd05106571-947  PTKc_CSF-1R
cd05104572-947  PTKc_Kit
cd05105572-940  PTKc_PDGFR_alpha
cd05107572-944  PTKc_PDGFR_beta
cd05054602-944  PTKc_VEGFR
cd00192614-943  PTKc
cd05102602-944  PTKc_VEGFR3
cd05103602-944  PTKc_VEGFR2
cd14207602-944  PTKc_VEGFR1
cd05053600-954  PTKc_FGFR
cd05099599-952  PTKc_FGFR4
cd05101596-943  PTKc_FGFR2
cd05098596-943  PTKc_FGFR1
cd05100600-939  PTKc_FGFR3
cd05045609-941  PTKc_RET
cd05032603-943  PTKc_InsR_like
cd05039603-936  PTKc_Csk_like
cd05044614-936  PTKc_c-ros
cd05034614-943  PTKc_Src_like
cd05036604-936  PTKc_ALK_LTK
cd05057604-941  PTKc_EGFR_like
cd05048604-944  PTKc_Ror
cd05049604-936  PTKc_Trk
cd05059610-944  PTKc_Tec_like
cd05050604-936  PTKc_Musk
cd05047615-940  PTKc_Tie
cd05068602-939  PTKc_Frk_like
cd05089608-953  PTKc_Tie1
cd05052603-936  PTKc_Abl
cd05051604-943  PTKc_DDR
cd05046605-944  PTK_CCK4
cd05041616-936  PTKc_Fes_like
cd05060616-943  PTKc_Syk_like
cd05148603-944  PTKc_Srm_Brk
cd05082603-943  PTKc_Csk
cd13999616-943  STKc_MAP3K-like
cd05085613-939  PTKc_Fer
cd05061603-943  PTKc_InsR
cd05056603-949  PTKc_FAK
cd05072603-956  PTKc_Lyn
cd05088601-949  PTKc_Tie2
cd05058614-941  PTKc_Met_Ron
cd05038605-939  PTKc_Jak_rpt2
cd05092601-943  PTKc_TrkA
cd05084613-944  PTKc_Fes
cd05083603-943  PTKc_Chk
cd05067602-943  PTKc_Lck_Blk
cd05035610-939  PTKc_TAM
cd05040614-943  PTKc_Ack_like
cd05113607-941  PTKc_Btk_Bmx
cd05073603-943  PTKc_Hck
cd05097604-943  PTKc_DDR_like
cd05091610-943  PTKc_Ror2
cd05062603-941  PTKc_IGF-1R
cd05108614-982  PTKc_EGFR
cd05095604-943  PTKc_DDR2
cd05112606-939  PTKc_Itk
cd05109614-941  PTKc_HER2
cd05096604-943  PTKc_DDR1
cd05033614-943  PTKc_EphR
cd14203614-943  PTKc_Src_Fyn_like
cd14204607-939  PTKc_Mer
cd05069603-956  PTKc_Yes
cd05075610-939  PTKc_Axl
cd05093607-943  PTKc_TrkB
cd05094607-943  PTKc_TrkC
cd05071603-943  PTKc_Src
cd05114606-939  PTKc_Tec_Rlk
cd00180616-943  PKc
cd05070603-956  PTKc_Fyn
cd05074606-943  PTKc_Tyro3
cd05043607-943  PTK_Ryk
cd05115607-939  PTKc_Zap-70
cd05090604-939  PTKc_Ror1
cd05111605-941  PTK_HER3
cd05110614-962  PTKc_HER4
cd05116616-936  PTKc_Syk
cd05063614-943  PTKc_EphR_A2
cd14205605-940  PTKc_Jak2_rpt2
cd14058616-944  STKc_TAK1
cd05081781-939  PTKc_Jak3_rpt2
cd05066614-943  PTKc_EphR_A
cd05080605-943  PTKc_Tyk2_rpt2
cd05065614-943  PTKc_EphR_B
cd05079616-939  PTKc_Jak1_rpt2
cd14059616-943  STKc_MAP3K12_13
cd14061615-939  STKc_MLK
cd06606613-935  STKc_MAPKKK
cd14206616-939  PTKc_Aatyk3
cd05064604-943  PTKc_EphR_A10
cd05042614-935  PTKc_Aatyk
cd14145601-939  STKc_MLK1
cd05087614-935  PTKc_Aatyk1
cd14146615-936  STKc_MLK4
cd05122611-939  PKc_STE
cd14003609-935  STKc_AMPK-like
cd13978616-936  STKc_RIP
cd14148788-936  STKc_MLK2
cd14147608-943  STKc_MLK3
cd14063610-943  PK_KSR
cd14060617-943  STKc_MLTK
cd14066616-883  STKc_IRAK
cd05086616-935  PTKc_Aatyk2
cd06628613-939  STKc_Byr2_like
cd14014614-935  STKc_PknB_like
cd06627609-935  STKc_Cdc7_like
cd14065616-943  PKc_LIMK_like
cd14121616-889  STKc_ULK3
cd14202602-889  STKc_ULK1
cd13992614-943  PK_GC
cd14009616-904  STKc_ATG1_ULK_like
cd07833608-891  STKc_CDKL
cd05117611-911  STKc_CAMK
cd07829616-875  STKc_CDK_like
cd06623608-935  PKc_MAPKK_plant_like
cd06612606-935  STKc_MST1_2
cd08215614-935  STKc_Nek
cd14155616-943  PKc_TESK
cd14008616-904  STKc_LKB1_CaMKK
cd13979608-935  STKc_Mos
cd08225609-943  STKc_Nek5
cd14158613-883  STKc_IRAK4
cd14007611-935  STKc_Aurora
cd14002608-903  STKc_STK36
cd06614610-935  STKc_PAK
cd07840616-891  STKc_CDK9_like
cd14120616-880  STKc_ULK1_2-like
cd14062792-943  STKc_Raf
cd05037610-936  PTK_Jak_rpt1
cd06605608-940  PKc_MAPKK
cd05118614-935  STKc_CMGC
cd13993609-890  STKc_Pat1_like
cd14221791-943  STKc_LIMK1
cd07848615-891  STKc_CDKL5
cd08217611-935  STKc_Nek2
cd14080612-878  STKc_TSSK-like
cd05581608-904  STKc_PDK1
cd14156616-939  PKc_LIMK_like_unk
cd14152610-943  STKc_KSR1
cd06608606-876  STKc_myosinIII_N_like
cd14150788-941  STKc_A-Raf
cd06629613-941  STKc_Bck1_like
cd06624596-939  STKc_ASK
cd14201603-889  STKc_ULK2
cd14151603-939  STKc_B-Raf
cd13996607-882  STKc_EIF2AK
cd14064773-943  PKc_TNNI3K
cd14042641-943  PK_GC-A_B
cd14069613-878  STKc_Chk1
cd05123616-933  STKc_AGC
cd14079613-879  STKc_AMPK_alpha
cd08530614-935  STKc_CNK2-like
cd07830614-884  STKc_MAK_like
cd05570614-954  STKc_PKC
cd07838616-884  STKc_CDK4_6_like
cd06620741-935  PKc_Byr1_like
cd06611606-881  STKc_SLK_like
cd07846612-979  STKc_CDKL2_3
cd14154616-943  STKc_LIMK
cd06631613-935  STKc_YSK4
cd06621792-935  PKc_Pek1_like
cd14027791-937  STKc_RIP1
cd06632613-875  STKc_MEKK1_plant
cd14222779-939  STKc_LIMK2
cd14001771-886  PKc_TOPK
cd14044764-943  PK_GC-C
cd14119616-904  STKc_LKB1
cd13975783-934  PKc_Dusty
cd07834614-882  STKc_MAPK
cd06610611-935  STKc_OSR1_SPAK
cd14090613-891  STKc_Mnk
cd06917799-893  STKc_NAK1_like
cd06622786-940  PKc_PBS2_like
cd14149788-892  STKc_C-Raf
cd14050611-935  PKc_Myt1
cd13994616-935  STKc_HAL4_like
cd07863780-882  STKc_CDK4
cd13997616-935  PKc_Wee1_like
cd07862784-882  STKc_CDK6
cd08529611-935  STKc_FA2-like
cd14190609-891  STKc_MLCK2
cd06616792-942  PKc_MKK4
cd14054780-937  STKc_BMPR2_AMHR2
cd14052614-881  PTKc_Wee1_fungi
cd14000792-943  STKc_LRRK
cd08219614-941  STKc_Nek3
cd05580608-906  STKc_PKA_like
cd14173614-891  STKc_Mnk2
cd06619792-892  PKc_MKK5
cd08223611-939  STKc_Nek4
cd06644606-881  STKc_STK10
cd05619779-913  STKc_nPKC_theta
cd14186608-908  STKc_PLK4
cd05078610-936  PTK_Jak2_rpt1
cd06609786-882  STKc_MST3_like
cd14010791-883  STKc_ULK4
cd14153610-943  PK_KSR2
cd14099613-935  STKc_PLK
cd14137614-875  STKc_GSK3
cd07842613-910  STKc_CDK8_like
cd14162611-879  STKc_TSSK4-like
cd07841611-880  STKc_CDK7
cd05589615-891  STKc_PKN
cd08224609-935  STKc_Nek6_7
cd08220614-934  STKc_Nek8
cd08228609-934  STKc_Nek6
cd14081613-890  STKc_BRSK1_2
cd08229794-934  STKc_Nek7
cd08218614-935  STKc_Nek1
cd14192614-891  STKc_MLCK3
cd06617786-889  PKc_MKK3_6
cd07858791-891  STKc_TEY_MAPK
cd08221765-935  STKc_Nek9
cd06607794-935  STKc_TAO
cd13998780-883  STKc_TGFbR-like
cd14144781-938  STKc_BMPR1
cd07859783-891  STKc_TDY_MAPK
cd14056614-881  STKc_TGFbR_I
cd07847641-891  STKc_CDKL1_4
cd07845790-882  STKc_CDK10
cd14078608-941  STKc_MELK
cd14025793-941  STKc_RIP4_like
cd06648606-889  STKc_PAK_II
cd07866608-882  STKc_BUR1
cd06615741-890  PKc_MEK
cd14208610-936  PTK_Jak3_rpt1
cd06613616-880  STKc_MAP4K3_like
cd14047793-883  STKc_EIF2AK2_PKR
cd13968616-831  PKc_like
cd06625613-942  STKc_MEKK3_like
cd14167607-913  STKc_CaMKI_alpha
cd06649741-896  PKc_MEK2
cd06650741-902  PKc_MEK1
cd06636606-881  STKc_MAP4K4_6_N
cd05616609-904  STKc_cPKC_beta
cd14664616-883  STK_BAK1_like
cd14177771-895  STKc_RSK4_C
cd07843790-883  STKc_CDC2L1
cd13977791-879  STKc_PDIK1L
cd06642794-889  STKc_STK25
cd07857791-888  STKc_MPK1
cd14199778-889  STKc_CaMKK2
cd06641794-881  STKc_MST3
cd14072609-891  STKc_MARK
cd05620791-933  STKc_nPKC_delta
cd14106769-891  STKc_DRAK
cd06618792-939  PKc_MKK7
cd14048794-885  STKc_EIF2AK3_PERK
cd14175771-895  STKc_RSK1_C
cd07856791-891  STKc_Sty1_Hog1
cd07849791-883  STKc_ERK1_2_like
cd14131808-939  PKc_Mps1
cd05077792-936  PTK_Jak1_rpt1
cd08222794-935  STKc_Nek11
cd07831791-891  STKc_MOK
cd06640794-881  STKc_MST4
cd14091640-895  STKc_RSK_C
cd14178787-895  STKc_RSK3_C
cd14176771-895  STKc_RSK2_C
cd14076613-904  STKc_Kin4
cd06630613-881  STKc_MEKK1
cd14118777-879  STKc_CAMKK
cd06643606-881  STKc_SLK
cd14084614-935  STKc_Chk2
cd07851597-880  STKc_p38
cd14077609-879  STKc_Kin1_2
cd13987792-878  STKc_SBK1
cd13985614-881  STKc_GAK_like
cd06633797-881  STKc_TAO3
cd14026793-936  STKc_RIP2
cd14075612-879  STKc_NIM1
cd14006616-891  STKc_MLCK-like
cd07832790-891  STKc_CCRK
cd14043797-936  PK_GC-2D
cd07853783-883  STKc_NLK
cd06638798-939  STKc_myosinIIIA_N
cd06634797-935  STKc_TAO2
cd14067781-934  STKc_LRRK1
cd14004614-889  STKc_PASK
cd07855783-891  STKc_ERK5
cd14174614-891  STKc_Mnk1
cd14049764-882  STKc_EIF2AK1_HRI
cd14185611-913  STKc_DCKL3
cd06637606-881  STKc_TNIK
cd13982793-935  STKc_IRE1
cd07879603-883  STKc_p38delta
cd05592614-913  STKc_nPKC_theta_like
cd05076792-936  PTK_Tyk2_rpt1
cd06655797-957  STKc_PAK2
cd14055781-889  STKc_TGFbR2_like
cd05615609-904  STKc_cPKC_alpha
cd06647794-889  STKc_PAK_I
cd14011793-903  PK_SCY1_like
cd07854791-881  STKc_MAPK4_6
cd14209608-939  STKc_PKA
cd05590614-991  STKc_nPKC_eta
cd06654797-939  STKc_PAK1
cd13989616-889  STKc_IKK
cd07873741-899  STKc_PCTAIRE1
cd14097612-879  STKc_STK33
cd14053781-883  STKc_ACVR2
cd14071614-917  STKc_SIK
cd14220767-933  STKc_BMPR1a
cd14095784-879  STKc_DCKL
cd14663611-912  STKc_SnRK3
cd07877783-891  STKc_p38alpha
cd14219809-938  STKc_BMPR1b
cd08528616-884  STKc_Nek10
cd06635797-881  STKc_TAO1
cd05613609-959  STKc_MSK1_N
cd14012791-935  PK_eIF2AK_GCN2_rpt1
cd07865616-880  STKc_CDK9
cd07880786-883  STKc_p38gamma
cd07852792-882  STKc_MAPK15-like
cd07839791-895  STKc_CDK5
cd07872781-895  STKc_PCTAIRE2
cd14057791-936  PK_ILK
cd05612608-889  STKc_PRKX_like
cd05611786-904  STKc_Rim15_like
cd06639606-939  STKc_myosinIIIB_N
cd07871781-894  STKc_PCTAIRE3
cd06659770-889  STKc_PAK6
cd14197794-928  STKc_DRAK1
cd05632786-986  STKc_GRK5
cd14193609-891  STKc_MLCK4
cd14038616-889  STKc_IKK_beta
cd14033791-939  STKc_WNK4
cd14070613-883  STKc_HUNK
cd14142809-881  STKc_ACVR1_ALK1
cd14104755-891  STKc_Titin
cd07870787-892  STKc_PFTAIRE2
cd07864611-883  STKc_CDK12
cd13983794-907  STKc_WNK
cd06656797-939  STKc_PAK3
cd14191777-891  STKc_MLCK1
cd14103616-891  STKc_MLCK
cd05578791-891  STKc_Yank1
cd05630791-889  STKc_GRK6
cd14165613-903  STKc_TSSK1_2-like
cd14184784-889  STKc_DCKL2
cd06626613-875  STKc_MEKK4
cd05631791-889  STKc_GRK4
cd05579791-905  STKc_MAST_like
cd14039616-889  STKc_IKK_alpha
cd05582614-891  STKc_RSK_N
cd14143767-938  STKc_TGFbR1_ACVR1b_ACVR1c
cd07850771-881  STKc_JNK
cd05572794-915  STKc_cGK
cd06652609-883  STKc_MEKK2
cd14187733-939  STKc_PLK1
cd14116608-917  STKc_Aurora-A
cd06657786-889  STKc_PAK4
cd07878783-891  STKc_p38beta
cd05608791-883  STKc_GRK1
cd07836791-891  STKc_Pho85
cd14159616-883  STKc_IRAK1
cd05587791-898  STKc_cPKC
cd14036610-879  STKc_GAK
cd14183781-891  STKc_DCKL1
cd06651791-939  STKc_MEKK3
cd14094794-911  STKc_CASK
cd05577787-889  STKc_GRK
cd14164794-891  STKc_TSSK6-like
cd14111786-889  STKc_SPEG_rpt2
cd14073611-903  STKc_NUAK
cd07844790-892  STKc_PCTAIRE_like
cd14098794-935  STKc_Rad53_Cds1
cd07876771-881  STKc_JNK2
cd14045781-881  PK_GC_unk
cd07875771-891  STKc_JNK1
cd05609798-902  STKc_MAST
cd14083607-913  STKc_CaMKI
cd14166607-913  STKc_CaMKI_gamma
cd06653791-883  STKc_MEKK3_like_u1
cd05595782-881  STKc_PKB_beta
cd05605791-881  STKc_GRK4_like
cd05585799-912  STKc_YPK1_like
cd14194774-891  STKc_DAPK1
cd06658786-893  STKc_PAK5
cd14086793-889  STKc_CaMKII
cd14109784-892  PK_Unc-89_rpt1
cd07869791-892  STKc_PFTAIRE1
cd14068792-935  STKc_LRRK2
cd14096616-881  STKc_RCK1-like
cd14200798-889  STKc_CaMKK1
cd05602609-889  STKc_SGK1
cd14093642-879  STKc_PhKG
pfam00047265-331  ig
cl11960265-331  Ig superfamily
cd14161607-891  STKc_NUAK2
cd14112794-891  STKc_Unc-89_rpt2
cd14114725-891  STKc_Twitchin_like
cd14189791-882  STKc_PLK3
cd05584614-891  STKc_p70S6K
cd13995794-889  STKc_MAP3K8
cd14665791-941  STKc_SnRK2-3
cd07874768-881  STKc_JNK3
cd14198794-891  STKc_DRAK2
cd07861791-881  STKc_CDK1_euk
cd14110787-883  STKc_obscurin_rpt2
cd14168607-913  STKc_CaMKI_delta
cd14188782-889  STKc_PLK2
cd14141768-883  STKc_ACVR2a
cd14113783-935  STKc_Trio_C
cd06645599-884  STKc_MAP4K3
cd07835791-895  STKc_CDK1_CdkB_like
cd07837791-903  STKc_CdkB_plant
cd14105783-891  STKc_DAPK
cd14082794-879  STKc_PKD
cd14223782-889  STKc_GRK2
cd14046614-880  STKc_EIF2AK4_GCN2_rpt2
cd06646794-884  STKc_MAP4K5
cd14087773-889  STKc_PSKH1
cd14195774-891  STKc_DAPK3
cd14140781-935  STKc_ACVR2b
cd14196783-933  STKc_DAPK2
cd05601808-880  STKc_CRIK
cd14180808-883  STKc_MSK2_C
cd05593791-881  STKc_PKB_gamma
cd14101790-881  STKc_PIM2
cd14108794-891  STKc_SPEG_rpt1
cd14018794-935  STKc_PINK1
cd05591614-883  STKc_nPKC_epsilon
cd13991786-873  STKc_NIK
cd14037731-881  STKc_NAK_like
cd07860791-881  STKc_CDK2_3
cd07867793-939  STKc_CDC2L6
cd14179808-883  STKc_MSK1_C
cd05614609-889  STKc_MSK2_N
cd14107782-935  STKc_obscurin_rpt1
cd13988774-891  STKc_TBK1
cd05603614-933  STKc_SGK2
cd08216611-889  PK_STRAD
cd05586799-881  STKc_Sck1_like
cd05606781-881  STKc_beta_ARK
cd05617791-889  STKc_aPKC_zeta
cd14074611-879  STKc_SNRK
cd14662791-903  STKc_SnRK2
cd14169793-913  STKc_CaMKI_beta
pfam13895253-344  Ig_2
cd05633782-889  STKc_GRK3
cd14092794-883  STKc_MSK_C
cd13986797-943  STKc_16
cd05573608-882  STKc_ROCK_NDR_like
cd14020792-883  STKc_KIS
cd14135790-883  STKc_PRP4
cd05594791-881  STKc_PKB_alpha
cd05604791-889  STKc_SGK3
cd14133791-883  PKc_DYRK_like
cd14170795-933  STKc_MAPKAPK2
cd13990794-881  STKc_TLK
cd05607783-889  STKc_GRK7
cd14136790-880  STKc_SRPK
cd14089793-905  STKc_MAPKAPK
cd14005808-881  STKc_PIM
cd07868793-883  STKc_CDK8
cd14172795-889  STKc_MAPKAPK3
cd14041702-889  STKc_TLK2
cd14125777-850  STKc_CK1_delta_epsilon
cd05618754-889  STKc_aPKC_iota
cd13974771-881  STKc_SHIK
cd14117742-889  STKc_Aurora-B_like
cd05588754-889  STKc_aPKC
cd14019783-929  STKc_Cdc7
cd14013808-843  STKc_SNT7_plant
smart00750774-880  KIND
cd14040702-889  STKc_TLK1
cd05598808-880  STKc_LATS
pfam07714610-943  Pkinase_Tyr
smart00221610-943  STYKc
smart00219610-943  TyrKc
smart00220611-939  S_TKc
pfam00069610-939  Pkinase
COG0515609-913  SPS1
PHA03209783-890  PHA03209
PLN00034741-890  PLN00034
PTZ00036791-903  PTZ00036
PTZ00267756-891  PTZ00267
PTZ00263602-889  PTZ00263
PTZ00024790-883  PTZ00024
PHA03212787-881  PHA03212
PHA02988774-943  PHA02988
PRK13184772-889  pknD
PTZ00426608-889  PTZ00426
PTZ00283794-947  PTZ00283
PTZ00266808-978  PTZ00266
PHA03211792-903  PHA03211
PLN00009791-901  PLN00009
smart00408265-331  IGc2
PLN03224775-842  PLN03224


Ontology Information


   
HPRD ID6769
Molecular ClassReceptor tyrosine kinase
Molecular FunctionLigand-dependent nuclear receptor activity (GO:0004879)
Biological ProcessSignal transduction (GO:0007165)  



SNP Information


View SNP Geneview Report   

Drug Information


Uniprot ID DrugBank ID Name Type
P36888DB00398SorafenibSmallMoleculeDrug
P36888DB01268SunitinibSmallMoleculeDrug
P36888DB08901PonatinibSmallMoleculeDrug
P36888DB09079NintedanibSmallMoleculeDrug

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO