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General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| FUBP1 | 8880 | Far upstream element (FUSE) binding protein 1  | 1 | This gene encodes a ssDNA binding protein that activates the far upstream element (FUSE) of c-myc and stimulates expression of c-myc in undifferentiated cells. Regulation of FUSE by FUBP occurs throug  |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 20089989    | 2010 | Cell line : - Source : VU University Medical Center, Amsterdam, The Netherlands Sample Type : CRC tumor and normal tissue No. of Sample : - Stage : - | Biochemical isolation to nano-LC-MS/MS analysis | Up-regulation | - | - |
| 20641205    | 2009 | Cell line : - Source : - Sample Type : - No. of Sample : - Stage : - | - | Up-regulation | - | - |
Gene Details

| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | -   | Chromosome | 1 |
| Location | 1p31.1 |
| Start | 77944055   |
| End | 77979205   |
| Strand | +   |
| Gene Sequence |    Download   Select all |
| Length | 35151   |
| OMIM ID | 603444    |
| HGNC ID | HGNC:4004    |
| Unigene ID | Hs.567380     |
| Ensembl ID | ENSG00000162613    |
| PharmGKB ID | -    |
mRNA Information
| mRNA ID | XM_005271326.2 |
|---|---|
| Exon | complement(<30563..>35151)   | mRNA Sequence |    Download   Select all |
| Length | 3709   |
CDS Information
| Location | join(202..321,9191..9281,11003..11041,11540..11579, 12108..12157,12251..12322,12455..12512,13975..14137, 14238..14336,14459..14560,14850..14952,15044..15144, 15491..15632,16276..16436,18711..18862,18943..19022, 22506..22634,23877..23951,29906..30051,32630..32676, 33564..33594) |
|---|---|
| CDS Sequence |    Download   Select all |
| CCDS ID | - |    
Protein Information
| Protein ID | NP_001290362.1 |
|---|---|
| Protein Name | Far upstream element (FUSE) binding protein 1 |
| Molecular Wt. (Da) | 69734 |
| Protein Sequence |    Download   Select all |
| Length | 665   |
| Uniprot ID | P13639 |    
| Ensembl Protein ID | ENSP00000307940   |    
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| Y | Phosphorylation | 58;- |
| Y | Phosphorylation | 58;- |
| T | Phosphorylation | 629;- |
| S | Phosphorylation | 630;- |
| S | Phosphorylation | 139 |
| S | Phosphorylation | 140 |
| T | Phosphorylation | 152 |
| T | Phosphorylation | 153 |
| S | Phosphorylation | 52 |
| S | Phosphorylation | 52 |
| S | Phosphorylation | 55 |
| S | Phosphorylation | 55 |
| K | Acetylation | 590 |
| K | Acetylation | 591 |
| Y | Phosphorylation | 626 |
| S | Phosphorylation | 98 |
| S | Phosphorylation | 99 |
| Y | Phosphorylation | 4 |
| Y | Phosphorylation | 4 |
| T | Phosphorylation | 206 |
| T | Phosphorylation | 207 |
| S | Phosphorylation | 84 |
| T | Phosphorylation | 87 |
| S | Phosphorylation | 84 |
| T | Phosphorylation | 228 |
| T | Phosphorylation | 229 |
| Y | Phosphorylation | 625 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING)      View   
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 902 |    CCNH |    9059 |    NP_001230.1 |    in vitro |    11239393    |
| 2965 |    GTF2H1 |    1807 |    NP_005307.1 |    in vitro;in vivo |    11239393    |
| 6606 |    SMN1 |    2646 |    NP_000335.1 |    in vitro;in vivo;yeast 2-hybrid |    10734235    |
| 7965 |    AIMP2 |    2915 |    NP_006294.2 |    in vitro;in vivo;yeast 2-hybrid |    12819782    |
| 10658 |    CUGBP1 |    3046 |    NP_001020767.1 |    yeast 2-hybrid |    16169070    |
| 10989 |    IMMT |    2658 |    NP_006830.2 |    in vitro |    11239393    |
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd00105 | 102-164  | KH-I |
| cl00098 | 102-164  | KH-I superfamily |
| cd00105 | 278-339  | KH-I |
| cl00098 | 278-339  | KH-I superfamily |
| cd00105 | 187-252  | KH-I |
| cl00098 | 187-252  | KH-I superfamily |
| cd00105 | 381-444  | KH-I |
| cl00098 | 381-444  | KH-I superfamily |
| pfam00013 | 102-164  | KH_1 |
| smart00322 | 102-168  | KH |
| smart00322 | 185-255  | KH |
| smart00322 | 381-447  | KH |
| smart00322 | 278-343  | KH |
| pfam00013 | 187-251  | KH_1 |
| pfam00013 | 280-339  | KH_1 |
| pfam00013 | 378-443  | KH_1 |
| cd02396 | 107-160  | PCBP_like_KH |
| cd02396 | 282-340  | PCBP_like_KH |
| pfam13014 | 111-152  | KH_3 |
| cd02396 | 190-252  | PCBP_like_KH |
| pfam13014 | 287-327  | KH_3 |
| cd02396 | 378-443  | PCBP_like_KH |
| pfam13014 | 389-431  | KH_3 |
| pfam09005 | 601-633  | DUF1897 |
| cl07567 | 601-633  | DUF1897 superfamily |
| cd02394 | 102-164  | vigilin_like_KH |
| pfam13014 | 196-239  | KH_3 |
| cd02394 | 391-444  | vigilin_like_KH |
| cd02394 | 189-252  | vigilin_like_KH |
| cd02394 | 278-337  | vigilin_like_KH |
| cd02393 | 190-251  | PNPase_KH |
| pfam07650 | 380-412  | KH_2 |
| cd02393 | 383-415  | PNPase_KH |
| pfam07650 | 189-219  | KH_2 |
| pfam07650 | 261-311  | KH_2 |
| cd02409 | 271-313  | KH-II |
| cd02395 | 378-445  | SF1_like-KH |
| cd02409 | 378-414  | KH-II |
| cd02410 | 382-417  | archeal_CPSF_KH |
| COG1094 | 190-344  | Krr1 |
| PRK13763 | 100-256  | PRK13763 |
| TIGR03665 | 189-309  | arCOG04150 |
| PRK13763 | 187-309  | PRK13763 |
| PRK11824 | 190-257  | PRK11824 |
| COG1094 | 95-256  | Krr1 |
| COG1185 | 190-257  | Pnp |
| TIGR03591 | 190-257  | polynuc_phos |
| PRK08406 | 381-412  | PRK08406 |
| TIGR03591 | 383-445  | polynuc_phos |
| PRK13764 | 247-321  | PRK13764 |
| COG1185 | 383-445  | Pnp |
| PRK11824 | 381-412  | PRK11824 |
| PRK00089 | 389-414  | era |
| COG1185 | 106-170  | Pnp |
| TIGR03665 | 280-449  | arCOG04150 |
| TIGR03591 | 106-168  | polynuc_phos |
| COG1855 | 247-323  | COG1855 |
| TIGR03675 | 375-417  | arCOG00543 |
Ontology Information
| HPRD ID | 579 |    
|---|---|
| Molecular Class | Transcription regulatory protein |
| Molecular Function | Transmembrane receptor protein tyrosine kinase activity (GO:0004714) |
| Biological Process | Cell communication (GO:0007154); Signal transduction (GO:0007165)   |
Drug Information
No matching records could be found.
External Links
| ArrayExpress | GO |    
|---|---|
| ICGC | GO |    
| Cancer3D | GO |    
| COSMIC | GO |    
| NCG | GO |    
| TSGene | GO |    
| Tumor Gene Family of Databases | GO |    
| CCDB | GO |    
| G2SBC | GO |    
| Osteosarcoma Database | GO |    
| RCDB | GO |    
