CoReCG

Evidence Information

Pubmed ID	Year	Sample Information	Techniques	Mechanism	Fold Change	Remark
23885148	2013	Cell line : - Source : Gastrointestinal endoscopic units and surgical clinics located in geographically different parts of Poland. Sample Type : CRC Tumor and normal tissue No. of Sample : 4 Stage : DukeStage A-D	QPCR assay,Microsatellite instability status analysis,Bisulfite modification and methylation-specific PCR	Hypermethylation	-	Decreased expression of�LATS1�in CRC was associated with promoter hypermethylation, but not MSI status. Such reduced expression may promote progression of CRC.

Gene Details

NC_000006.11 (149979289..150039392, complement)
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Gene Type	protein coding
Gene Family	-
Description	The protein encoded by this gene is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is phosphorylated in a cell-cycle dependent manner, with late prophase phosphorylation remaining through metaphase. The N-terminal region of the protein binds CDC2 to form a complex showing reduced H1 histone kinase activity, indicating a role as a negative regulator of CDC2/cyclin A. In addition, the C-terminal kinase domain binds to its own N-terminal region, suggesting potential negative regulation through interference with complex formation via intramolecular binding. Biochemical and genetic data suggest a role as a tumor suppressor. This is supported by studies in knockout mice showing development of soft-tissue sarcomas, ovarian stromal cell tumors and a high sensitivity to carcinogenic treatments. Two protein-coding transcripts and one non-protein coding transcript have been found for this gene. [provided by RefSeq, Jul 2012]
Chromosome	6
Location	6q25.1
Start	149979289
End	150039392
Strand	-
Gene Sequence	Download Select all
Length	60104
OMIM ID	603473
HGNC ID	HGNC:6514
Unigene ID	Hs.549084
Ensembl ID	ENSG00000131023
PharmGKB ID	PA30301

mRNA Information

mRNA ID	?NM_001270519.1
Exon
mRNA Sequence	Download Select all
Length

CDS Information

Location
CDS Sequence	Download Select all
CCDS ID	CCDS34551.1

Protein Information

Protein ID	NP_001257448.1
Protein Name	large tumor suppressor kinase 1
Molecular Wt. (Da)	0
Protein Sequence	Download Select all
Length	1130
Uniprot ID	Q9Y2F9
Ensembl Protein ID	ENSP00000254977

Post-translational Modification Information (Source : HPRD)

Residue	Type	site
S	Phosphorylation	464
T	Phosphorylation	490
S	Phosphorylation	613
S	Phosphorylation	613;-
S	Phosphorylation	334;-
S	Phosphorylation	335;-
S	Phosphorylation	464;-
S	Phosphorylation	674;-
T	Phosphorylation	246
S	Phosphorylation	278
S	Phosphorylation	244
T	Phosphorylation	261
T	Phosphorylation	611
S	Phosphorylation	1111
S	Phosphorylation	462

Enzyme Information

No matching records could be found.

PPi Information

(Click to view network : Source STRING) View

Interactant Gene ID (Source: HPRD)	Gene Symbol	HPRD ID	Ref Seq ID	Technique	References
3984	LIMK1	3210	NP_002305.1	in vitro;in vivo	15220930
6789	STK4	5395	NP_006273.1	in vitro	15688006
7791	ZYX	3592	NP_003452.1	in vitro;in vivo	10831611

Pathway Information

Pathway Name	Pathway ID
Hippo signaling pathway	hsa04390

Structure Information

No matching records could be found.

Domain Information

ID	Location	Description
cd05625	703-1084	STKc_LATS1
cl21453	703-1084	PKc_like superfamily
cd14397	103-143	UBA_LATS1
cl21463	103-143	UBA_like_SF superfamily
cd05598	703-1084	STKc_LATS
cd05626	703-1084	STKc_LATS2
cd05573	703-1081	STKc_ROCK_NDR_like
cd05599	705-1057	STKc_NDR_like
cd05629	705-1083	STKc_NDR_like_fungal
cd05627	705-1083	STKc_NDR2
cd05600	693-1081	STKc_Sid2p_like
cd05123	711-1010	STKc_AGC
cd05628	705-1083	STKc_NDR1
cd05579	714-1014	STKc_MAST_like
cd05601	709-1046	STKc_CRIK
cd05597	705-1080	STKc_DMPK_like
cd05596	688-1056	STKc_ROCK
cd05580	708-1040	STKc_PKA_like
cd05611	708-1015	STKc_Rim15_like
cd05574	705-1029	STKc_phototropin_like
cd05570	709-1054	STKc_PKC
cd05624	695-1047	STKc_MRCK_beta
cd05622	691-1046	STKc_ROCK1
cd05623	694-1047	STKc_MRCK_alpha
cd05621	694-1046	STKc_ROCK2
cd05581	705-1010	STKc_PDK1
cd05584	708-1063	STKc_p70S6K
cd05609	705-1015	STKc_MAST
cd05575	709-1080	STKc_SGK
cd05582	709-1041	STKc_RSK_N
cd05585	711-1064	STKc_YPK1_like
cd14209	705-1040	STKc_PKA
cd05612	705-1040	STKc_PRKX_like
cd05592	709-1053	STKc_nPKC_theta_like
cd05572	711-1010	STKc_cGK
cd05571	709-1055	STKc_PKB
cd05583	711-1013	STKc_MSK_N
cd05610	705-1040	STKc_MASTL
cd05578	705-1010	STKc_Yank1
cd05589	705-1041	STKc_PKN
cd05587	708-1041	STKc_cPKC
cd14003	708-1009	STKc_AMPK-like
cd05117	705-1009	STKc_CAMK
cd05614	705-1039	STKc_MSK2_N
cd05619	699-1040	STKc_nPKC_theta
cd14007	705-1011	STKc_Aurora
cd05591	709-1054	STKc_nPKC_epsilon
cd05620	709-1040	STKc_nPKC_delta
cd05586	711-1041	STKc_Sck1_like
cd05604	708-1042	STKc_SGK3
cd05603	709-1041	STKc_SGK2
cd05590	709-1041	STKc_nPKC_eta
cd05595	709-1054	STKc_PKB_beta
cd05588	709-1051	STKc_aPKC
cd05577	711-1015	STKc_GRK
cd05613	705-1033	STKc_MSK1_N
cd05602	703-1041	STKc_SGK1
cd06606	705-1010	STKc_MAPKKK
cd14014	708-995	STKc_PknB_like
cd14099	705-1010	STKc_PLK
cd05616	705-1040	STKc_cPKC_beta
cd05605	705-1015	STKc_GRK4_like
cd14009	711-1009	STKc_ATG1_ULK_like
cd14008	711-1010	STKc_LKB1_CaMKK
cd05630	705-1015	STKc_GRK6
cd05122	704-1010	PKc_STE
cd05594	697-1040	STKc_PKB_alpha
cd05593	696-1051	STKc_PKB_gamma
cd05606	711-1033	STKc_beta_ARK
cd05617	705-1053	STKc_aPKC_zeta
cd05615	705-1040	STKc_cPKC_alpha
cd05631	705-1015	STKc_GRK4
cd08215	705-1010	STKc_Nek
cd00180	711-1008	PKc
cd05618	705-1053	STKc_aPKC_iota
cd05632	702-1015	STKc_GRK5
cd14663	709-1009	STKc_SnRK3
cd14098	708-1009	STKc_Rad53_Cds1
cd06627	711-1010	STKc_Cdc7_like
cd06614	705-1011	STKc_PAK
cd05607	705-1015	STKc_GRK7
cd06632	707-1009	STKc_MEKK1_plant
cd14084	709-1008	STKc_Chk2
cd06623	705-1014	PKc_MAPKK_plant_like
cd08217	708-1010	STKc_Nek2
cd14223	709-1055	STKc_GRK2
cd05633	709-1067	STKc_GRK3
cd14081	709-1010	STKc_BRSK1_2
cd14069	705-1010	STKc_Chk1
cd05608	705-1028	STKc_GRK1
cd14121	711-1009	STKc_ULK3
cd05118	707-1010	STKc_CMGC
cd06648	697-1011	STKc_PAK_II
cd14080	708-1010	STKc_TSSK-like
cd14116	709-1009	STKc_Aurora-A
cd14120	711-1009	STKc_ULK1_2-like
cd06625	707-1010	STKc_MEKK3_like
cd06612	711-1010	STKc_MST1_2
cd14006	711-1008	STKc_MLCK-like
cd06609	705-1019	STKc_MST3_like
cd14167	711-1009	STKc_CaMKI_alpha
cd07830	708-1010	STKc_MAK_like
cd14166	702-1009	STKc_CaMKI_gamma
cd13996	705-995	STKc_EIF2AK
cd06626	712-1009	STKc_MEKK4
cd06610	708-1010	STKc_OSR1_SPAK
cd06629	705-1009	STKc_Bck1_like
cd14079	709-1010	STKc_AMPK_alpha
cd14083	702-995	STKc_CaMKI
cd14095	709-1008	STKc_DCKL
cd13994	711-950	STKc_HAL4_like
cd08529	705-995	STKc_FA2-like
cd14073	708-950	STKc_NUAK
cd13999	711-987	STKc_MAP3K-like
cd06628	704-1009	STKc_Byr2_like
cd14096	708-1009	STKc_RCK1-like
cd14086	711-1014	STKc_CaMKII
cd08530	705-1008	STKc_CNK2-like
cd06659	705-1010	STKc_PAK6
cd14118	711-1008	STKc_CAMKK
cd14169	702-996	STKc_CaMKI_beta
cd14097	711-954	STKc_STK33
cd14137	704-1011	STKc_GSK3
cd14165	710-1010	STKc_TSSK1_2-like
cd14168	696-1009	STKc_CaMKI_delta
cd14162	709-1010	STKc_TSSK4-like
cd06644	692-1024	STKc_STK10
cd14106	709-1010	STKc_DRAK
cd14078	709-950	STKc_MELK
cd14186	711-1009	STKc_PLK4
cd14185	709-1009	STKc_DCKL3
cd14010	711-1009	STKc_ULK4
cd14117	709-1011	STKc_Aurora-B_like
cd14202	702-1010	STKc_ULK1
cd14188	705-1010	STKc_PLK2
cd14002	712-1009	STKc_STK36
cd06613	704-1010	STKc_MAP4K3_like
cd14091	710-1038	STKc_RSK_C
cd06605	707-1011	PKc_MAPKK
cd14187	705-1012	STKc_PLK1
cd14071	708-1010	STKc_SIK
cd07840	705-1010	STKc_CDK9_like
cd14092	706-1012	STKc_MSK_C
cd14189	705-1010	STKc_PLK3
cd06647	702-1011	STKc_PAK_I
cd14201	711-1011	STKc_ULK2
cd14074	709-1009	STKc_SNRK
cd06631	711-1009	STKc_YSK4
cd14199	711-1009	STKc_CaMKK2
cd06917	703-1012	STKc_NAK1_like
cd14093	750-1010	STKc_PhKG
cd06611	708-1014	STKc_SLK_like
cd14046	705-943	STKc_EIF2AK4_GCN2_rpt2
cd06658	705-1011	STKc_PAK5
cd14087	708-996	STKc_PSKH1
cd07829	705-1010	STKc_CDK_like
cd07834	708-1046	STKc_MAPK
cd06643	708-1021	STKc_SLK
cd14082	709-988	STKc_PKD
cd06630	705-1011	STKc_MEKK1
cd13978	711-951	STKc_RIP
cd06657	705-1010	STKc_PAK4
cd08221	704-1010	STKc_Nek9
cd07832	711-1010	STKc_CCRK
cd07841	705-1012	STKc_CDK7
cd14200	711-1009	STKc_CaMKK1
cd14103	711-1008	STKc_MLCK
cd08224	704-950	STKc_Nek6_7
cd14072	708-963	STKc_MARK
cd13993	707-951	STKc_Pat1_like
cd05576	713-1010	STKc_RPK118_like
cd08528	711-995	STKc_Nek10
cd14662	708-1009	STKc_SnRK2
cd14179	704-988	STKc_MSK1_C
cd07833	707-1010	STKc_CDKL
cd08218	705-995	STKc_Nek1
cd06655	702-1011	STKc_PAK2
cd06656	702-1011	STKc_PAK3
cd14665	708-1009	STKc_SnRK2-3
cd14175	705-1027	STKc_RSK1_C
cd06608	708-1009	STKc_myosinIII_N_like
cd14181	765-1010	STKc_PhKG2
cd06652	709-985	STKc_MEKK2
cd14004	705-1010	STKc_PASK
cd13990	711-995	STKc_TLK
cd14161	708-950	STKc_NUAK2
cd06653	709-1009	STKc_MEKK3_like_u1
cd14182	753-1011	STKc_PhKG1
cd14107	711-1010	STKc_obscurin_rpt1
cd14019	708-1010	STKc_Cdc7
cd14052	705-942	PTKc_Wee1_fungi
cd14173	711-1009	STKc_Mnk2
cd14075	705-1009	STKc_NIM1
cd14070	709-950	STKc_HUNK
cd14132	705-1011	STKc_CK2_alpha
cd13997	705-1008	PKc_Wee1_like
cd06654	702-1011	STKc_PAK1
cd14089	709-1008	STKc_MAPKAPK
cd14131	705-1009	PKc_Mps1
cd08225	708-995	STKc_Nek5
cd06615	703-957	PKc_MEK
cd07831	708-1010	STKc_MOK
cd08222	705-963	STKc_Nek11
cd14192	709-988	STKc_MLCK3
cd08219	708-991	STKc_Nek3
cd14178	711-1017	STKc_RSK3_C
cd14113	703-962	STKc_Trio_C
cd08220	707-1008	STKc_Nek8
cd14184	709-1009	STKc_DCKL2
cd14076	709-1009	STKc_Kin4
cd06651	709-1009	STKc_MEKK3
cd07855	708-1012	STKc_ERK5
cd06640	702-949	STKc_MST4
cd14193	707-988	STKc_MLCK4
cd07838	711-1010	STKc_CDK4_6_like
cd14183	709-1009	STKc_DCKL1
cd14090	711-1009	STKc_Mnk
cd14180	711-1003	STKc_MSK2_C
cd14005	711-1010	STKc_PIM
cd14134	705-954	PKc_CLK
cd14119	711-1010	STKc_LKB1
cd14190	711-1010	STKc_MLCK2
cd13989	711-971	STKc_IKK
cd14197	709-1010	STKc_DRAK1
cd07852	708-1011	STKc_MAPK15-like
cd14176	711-1029	STKc_RSK2_C
cd14077	708-950	STKc_Kin1_2
cd06642	702-956	STKc_STK25
cd06645	705-1009	STKc_MAP4K3
cd06641	702-957	STKc_MST3
cd00192	709-950	PTKc
cd14196	711-958	STKc_DAPK2
cd14016	704-854	STKc_CK1
cd13987	711-995	STKc_SBK1
cd14048	705-995	STKc_EIF2AK3_PERK
cd14177	765-985	STKc_RSK4_C
cd08228	709-950	STKc_Nek6
cd14194	711-996	STKc_DAPK1
cd14133	708-1010	PKc_DYRK_like
cd07848	707-957	STKc_CDKL5
cd07857	708-1009	STKc_MPK1
cd13985	709-995	STKc_GAK_like
cd14047	705-944	STKc_EIF2AK2_PKR
cd14105	711-996	STKc_DAPK
cd06646	708-1009	STKc_MAP4K5
cd14171	709-1009	STKc_MAPKAPK5
cd06624	711-1009	STKc_ASK
cd07835	705-1010	STKc_CDK1_CdkB_like
cd14174	711-1011	STKc_Mnk1
cd06620	699-950	PKc_Byr1_like
cd14085	709-1011	STKc_CaMKIV
cd07880	702-1041	STKc_p38gamma
cd14027	711-1011	STKc_RIP1
cd06638	708-987	STKc_myosinIIIA_N
cd08229	709-950	STKc_Nek7
cd14094	747-1011	STKc_CASK
cd07860	704-1010	STKc_CDK2_3
cd07866	708-1010	STKc_BUR1
cd14198	709-995	STKc_DRAK2
cd06650	705-1015	PKc_MEK1
cd07879	705-1010	STKc_p38delta
cd14191	711-1010	STKc_MLCK1
cd14172	709-996	STKc_MAPKAPK3
cd07836	705-1010	STKc_Pho85
cd14109	709-1010	PK_Unc-89_rpt1
cd08223	705-995	STKc_Nek4
cd06621	705-955	PKc_Pek1_like
cd14114	711-1010	STKc_Twitchin_like
cd14195	711-1011	STKc_DAPK3
cd07851	705-1011	STKc_p38
cd14104	711-1011	STKc_Titin
cd14050	705-942	PKc_Myt1
cd14163	709-1010	STKc_TSSK3-like
cd14164	709-950	STKc_TSSK6-like
cd07854	703-1033	STKc_MAPK4_6
cd14017	708-854	STKc_TTBK
cd07849	705-1009	STKc_ERK1_2_like
cd07878	707-1064	STKc_p38beta
cd07843	714-958	STKc_CDC2L1
cd07864	699-964	STKc_CDK12
cd06639	708-991	STKc_myosinIIIB_N
cd07861	705-950	STKc_CDK1_euk
cd14108	709-1010	STKc_SPEG_rpt1
cd06622	707-1011	PKc_PBS2_like
cd07863	708-1010	STKc_CDK4
cd07839	707-1010	STKc_CDK5
cd14115	711-1009	STKc_Kalirin_C
cd07845	705-957	STKc_CDK10
cd06618	696-1011	PKc_MKK7
cd14012	743-1009	PK_eIF2AK_GCN2_rpt1
cd14101	711-1011	STKc_PIM2
cd14322	103-141	UBA_LATS
cd07837	707-1010	STKc_CdkB_plant
cd14066	711-950	STKc_IRAK
cd13974	802-988	STKc_SHIK
cd14088	716-995	STKc_CaMK_like
cd06636	704-956	STKc_MAP4K4_6_N
cd14039	711-951	STKc_IKK_alpha
cd05041	711-995	PTKc_Fes_like
cd13983	825-1010	STKc_WNK
cd07846	707-950	STKc_CDKL2_3
cd14058	711-995	STKc_TAK1
cd14100	711-1009	STKc_PIM1
cd07877	697-1010	STKc_p38alpha
cd14145	699-993	STKc_MLK1
cd14226	708-991	PKc_DYRK1
cd14041	705-996	STKc_TLK2
cd13979	711-950	STKc_Mos
cd06649	705-949	PKc_MEK2
cd07850	705-950	STKc_JNK
cd14210	708-950	PKc_DYRK
cd13982	752-1010	STKc_IRE1
cd07870	765-1010	STKc_PFTAIRE2
cd14212	708-950	PKc_YAK1
cd14222	711-947	STKc_LIMK2
cd07847	707-948	STKc_CDKL1_4
cd14061	711-972	STKc_MLK
cd07876	689-963	STKc_JNK2
cd13988	711-950	STKc_TBK1
cd13986	708-985	STKc_16
cd05044	709-996	PTKc_c-ros
cd07844	820-1010	STKc_PCTAIRE_like
cd07871	705-957	STKc_PCTAIRE3
cd14158	711-950	STKc_IRAK4
cd06619	710-1009	PKc_MKK5
cd14038	711-966	STKc_IKK_beta
cd07858	705-1010	STKc_TEY_MAPK
cd14026	714-849	STKc_RIP2
cd08216	719-1018	PK_STRAD
cd14111	753-963	STKc_SPEG_rpt2
cd14170	772-1054	STKc_MAPKAPK2
cd05080	702-868	PTKc_Tyk2_rpt2
cd14148	711-995	STKc_MLK2
cd07856	703-1009	STKc_Sty1_Hog1
cd06617	705-1011	PKc_MKK3_6
cd07873	705-963	STKc_PCTAIRE1
cd06616	825-1014	PKc_MKK4
cd06637	704-956	STKc_TNIK
cd14154	772-954	STKc_LIMK
cd14102	711-1009	STKc_PIM3
cd14065	711-944	PKc_LIMK_like
cd14049	811-990	STKc_EIF2AK1_HRI
cd14059	781-989	STKc_MAP3K12_13
cd13991	711-849	STKc_NIK
cd07875	689-963	STKc_JNK1
cd05038	707-963	PTKc_Jak_rpt2
cd05079	701-995	PTKc_Jak1_rpt2
cd14060	712-972	STKc_MLTK
cd05059	700-995	PTKc_Tec_like
cd05072	708-995	PTKc_Lyn
cd14147	709-983	STKc_MLK3
cd07865	701-853	STKc_CDK9
cd14040	705-996	STKc_TLK1
cd06633	702-951	STKc_TAO3
cd05060	709-950	PTKc_Syk_like
cd13995	714-955	STKc_MAP3K8
cd14023	912-1010	PK_TRB1
cd07874	689-963	STKc_JNK3
cd13977	778-944	STKc_PDIK1L
cd14221	711-954	STKc_LIMK1
cd14146	711-980	STKc_MLK4
cd07872	705-1013	STKc_PCTAIRE2
cd14225	708-973	PKc_DYRK4
cd07862	708-999	STKc_CDK6
cd14135	708-947	STKc_PRP4
cd14022	912-1010	PK_TRB2
cd13981	769-848	STKc_Bub1_BubR1
cd07853	820-963	STKc_NLK
cd14398	104-143	UBA_LATS2
cd06607	704-950	STKc_TAO
cd05085	711-962	PTKc_Fer
cd05035	709-950	PTKc_TAM
cd05116	709-997	PTKc_Syk
cd14229	711-948	STKc_HIPK3
cd05113	708-963	PTKc_Btk_Bmx
cd05046	708-950	PTK_CCK4
cd13976	912-1010	PK_TRB
cd14011	823-1010	PK_SCY1_like
cd05039	706-888	PTKc_Csk_like
cd05084	709-962	PTKc_Fes
cd13968	711-848	PKc_like
cd05075	709-950	PTKc_Axl
cd07859	806-1030	STKc_TDY_MAPK
cd14064	711-950	PKc_TNNI3K
cd14138	703-838	PTKc_Wee1a
cd05056	709-864	PTKc_FAK
cd05094	709-996	PTKc_TrkC
cd14024	746-1009	PK_TRB3
cd05032	708-948	PTKc_InsR_like
cd14664	711-950	STK_BAK1_like
cd05049	708-950	PTKc_Trk
cd05074	695-950	PTKc_Tyro3
cd06635	702-951	STKc_TAO1
cd14215	800-946	PKc_CLK2
cd07869	705-963	STKc_PFTAIRE1
cd05067	708-995	PTKc_Lck_Blk
cd13980	709-954	STKc_Vps15
cd05092	711-950	PTKc_TrkA
cd05081	708-849	PTKc_Jak3_rpt2
cd07842	712-1010	STKc_CDK8_like
cd14224	708-950	PKc_DYRK2_3
cd14125	811-863	STKc_CK1_delta_epsilon
cd14037	708-852	STKc_NAK_like
cd05036	708-954	PTKc_ALK_LTK
cd14228	708-950	STKc_HIPK1
cd14063	706-995	PK_KSR
cd14036	813-996	STKc_GAK
cd14205	708-944	PTKc_Jak2_rpt2
cd13998	778-996	STKc_TGFbR-like
cd14214	841-946	PKc_CLK3
cd05093	709-950	PTKc_TrkB
cd14112	750-961	STKc_Unc-89_rpt2
cd14227	708-950	STKc_HIPK2
cd06634	702-951	STKc_TAO2
cd14136	821-946	STKc_SRPK
cd05082	708-859	PTKc_Csk
cd05040	709-952	PTKc_Ack_like
cd05053	700-950	PTKc_FGFR
cd05090	725-950	PTKc_Ror1
cd14110	765-959	STKc_obscurin_rpt2
cd14149	711-1030	STKc_C-Raf
pfam00627	101-138	UBA
cd05033	706-950	PTKc_EphR
cd05066	709-849	PTKc_EphR_A
cd05073	709-995	PTKc_Hck
cd05099	709-973	PTKc_FGFR4
cd05115	699-950	PTKc_Zap-70
cd14062	820-950	STKc_Raf
cd14031	711-950	STKc_WNK3
cd14000	778-995	STKc_LRRK
cd14139	705-836	PTKc_Wee1b
cd14203	709-995	PTKc_Src_Fyn_like
cd14013	815-852	STKc_SNT7_plant
cd05114	700-957	PTKc_Tec_Rlk
cd05055	709-950	PTKc_PDGFR
cd14211	708-948	STKc_HIPK
cd14213	800-950	PKc_CLK1_4
cd14051	705-838	PTKc_Wee1
cd14020	815-946	STKc_KIS
cd05097	711-945	PTKc_DDR_like
cd05098	697-963	PTKc_FGFR1
cd05120	755-851	APH_ChoK_like
cd14054	711-959	STKc_BMPR2_AMHR2
cd14067	784-962	STKc_LRRK1
cd14150	708-950	STKc_A-Raf
cd14159	711-949	STKc_IRAK1
cd13975	795-850	PKc_Dusty
cd05065	705-950	PTKc_EphR_B
cd14151	709-950	STKc_B-Raf
cd05043	811-957	PTK_Ryk
pfam00433	1029-1084	Pkinase_C
cl11395	1029-1084	Pkinase_C superfamily
cd14055	819-961	STKc_TGFbR2_like
cd14025	775-1019	STKc_RIP4_like
cd05095	711-869	PTKc_DDR2
cd14128	816-854	STKc_CK1_alpha
cd05100	709-963	PTKc_FGFR3
cd05148	702-995	PTKc_Srm_Brk
cd14144	709-943	STKc_BMPR1
cd14143	774-943	STKc_TGFbR1_ACVR1b_ACVR1c
cd05121	781-850	ABC1_ADCK3-like
cd14127	816-863	STKc_CK1_fungal
PRK14879	772-849	PRK14879
cd08226	800-972	PK_STRAD_beta
cd05034	709-958	PTKc_Src_like
PHA02882	767-853	PHA02882
smart00133	1011-1082	S_TK_X
cd14018	788-850	STKc_PINK1
cd14057	914-989	PK_ILK
cd05083	709-849	PTKc_Chk
cd05071	702-861	PTKc_Src
cd05064	706-848	PTKc_EphR_A10
cd05096	711-944	PTKc_DDR1
cd14204	700-870	PTKc_Mer
COG3642	774-849	Bud32
TIGR03724	774-849	arch_bud32
smart00220	705-1010	S_TKc
pfam00069	705-1010	Pkinase
PTZ00263	710-1046	PTZ00263
PTZ00426	696-1056	PTZ00426
COG0515	705-1039	SPS1
PHA03390	699-1011	pk1
smart00221	706-995	STYKc
smart00219	706-995	TyrKc
pfam07714	705-1013	Pkinase_Tyr
PTZ00267	721-963	PTZ00267
PTZ00024	698-989	PTZ00024
PRK13184	708-950	pknD
PTZ00283	709-995	PTZ00283
PTZ00036	652-1062	PTZ00036
TIGR03903	726-948	TOMM_kin_cyc
PTZ00266	708-950	PTZ00266
PLN00009	700-1015	PLN00009
PHA03210	806-944	PHA03210
PLN00034	703-1009	PLN00034
PHA03212	697-995	PHA03212
PHA03211	811-975	PHA03211
PHA03207	708-950	PHA03207
PHA03209	819-996	PHA03209
PLN03224	811-855	PLN03224
TIGR01982	721-849	UbiB
PRK10263	448-596	PRK10263
PLN03225	694-854	PLN03225
PRK14950	473-558	PRK14950
PRK10263	467-655	PRK10263
PRK10263	369-588	PRK10263
COG0661	751-862	AarF
PRK14950	483-593	PRK14950

Ontology Information

HPRD ID	10377
Molecular Class	Serine/threonine kinase
Molecular Function	Deacetylase activity (GO:0019213)
Biological Process	Cell communication (GO:0007154); Signal transduction (GO:0007165)

SNP Information

View SNP Geneview Report