CoReCG

Search results:

General Information

Gene_Symbol	Gene_ID	Gene_Name	Chromosome	Alias
NOTCH1	4851	Notch homolog 1, translocation-associated (Drosophila)	9	hN1; TAN1

Evidence
Gene
mRNA
CDS
Protein
PTM
Enzyme
PPi
Pathway
Structural
Domain
Ontology
SNP
Drug
External Links

Evidence Information

Pubmed ID	Year	Sample Information	Techniques	Mechanism	Fold Change	Remark
22863622	2012	Cell line : - Source : The Jackson Laboratories, Rosa-Notch1 mice (a gift from D. Melton, Harvard Stem Cell Institute, Harvard University, Boston, Massachusetts, USA). Sample Type : Mouse model No. of Sample : - Stage : -	Immunohistochemistry, In situ hybridization, Microarray analysis, Western blot and RT-PCR analyses.	Chromatin modification	-	Notch both suppresses tumor progression and enhances tumor initiation.
18777195	2009	Cell line : - Source : - Sample Type : CRC tumor and normal tissue No. of Sample : 237 colorectal cancer samples with matched adjacent normal tissues and a series of 46 normal colorectal specimens Stage : TNM Stage I-IV	Immunohistochemistry, real-time polymerase chain reaction, and Western blotting	Up-regulation	-	Notch1 expression correlated closely with colorectal cancer and may play an oncogenic role during colonic carcinogenesis.
20058190	2010	Cell line : - Source : - Sample Type : CRC tumor and normal tissue No. of Sample : 223 colorectal cancer and adjacent tissues Stage : TNM Stage I-IV	Immunohistochemistry, Kaplan-Meier and Cox proportional-hazards regression.	Up-regulation	-	Notch1 might serve as a novel prognostic marker that is independent of, and additive to, the TNM staging system.
21378202	2011	Cell line : - Source : Xijing Hospital of Digestive Diseases and Tianjin Union Medicine Centre. Sample Type : Case control study No. of Sample : 1003 CRC patients Stage : -	Immunohistochemistry	Up-regulation	-	Notch1 and Notch2 may be independent adverse prognostic predictors for patients with colorectal cancer. Notch1 and Notch2 were proved to be inversely correlated with tumor differentiation, depth of invasion, lymph node metastases, distant metastasis. Notch 1 positive CRC patient show poor survival.
21771876	2011	Cell line : - Source : Colorectal Cancer Registry, Tianjin Union Medicine Centre. Sample Type : CRC tumor and normal tissue No. of Sample : 941 Stage : -	Tissue microarray, immunohistochemistry	Up-regulation	-	Notch1 is an independent predictor of prognosis for patients with colorectal cancer. Targeting Notch1 and nuclear factor Kappa B (NF-kappa B) might be a promising strategy for colorectal cancer treatment.
24312514	2013	Cell line : - Source : Second Affiliated Hospital of Harbin Medical University, China Sample Type : - No. of Sample : 220 patients with ulcerative colitis, 232 patients with colorectal adenoma and 449 patients with colorectal cancer Stage : -	Immunohistochemistry	Up-regulation	-	Expression level of Notch1 was gradually increased from precancerous lesions to cancer. It might play as an oncogene in the CRC development, and might be potentially used as a biomarker for prognosis of CRCs. Colorectal cancer patients with high expression levels of Notch1 showed lower overall survival (OS) and disease-free survival (DFS) rates than those patients with low Notch1 expression.

Gene Details

Chromosome: 9; NC_000009.11 (139388896..139440238, complement)
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Gene Type	protein coding
Gene Family	Ankyrin repeat domain containing
Description	This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play multiple roles during development. [provided by RefSeq, Jul 2008]
Chromosome	9
Location	9q34.3
Start	136494444
End	136545786
Strand	-
Gene Sequence	>gi\|568815589:c136545786-136494444 Homo sapiens chromosome 9, GRCh38.p2 Primary Assembly ATGCCGCCGCTCCTGGCGCCCCTGCTCTGCCTGGCGCTGCTGCCCGCGCTCGCCGCACGAGGTAGGCGCC CACCCACCCGCGAGCCCCCACTTTCCGCGCCCTTTGGAAACTTTGGCGGCGCCCGGCGCGCGCGCCCCAC GGCTGGGAGCGGGCGGCGGGGAGGCCAGCATGGAGAGGGAAAAGCGGGCGGCCCGGGGCGTGGGGTTCTG GAGTCCCGGGATCAGGGAGGACCGACCTTCCCCCTCGATCCCCCCGTGGAGGCGGACTCGCGCCGCCCGT GCCTGGAGCCGAGTTAGGAGGCCGGTGTGGGGTGCTGGGGCCCCGGAGGCCCTACTCCGGGCCCGCCCTT CACCCGCCGCGCGTGGGGCTTGCCGCCGGTCGGCCGGGCGGGCGGGCTGCCTACTATTTTTCGATTTGAA TAGAGTCGGTTTTGGTTTCCTGTTGCTTCTCCGGGCCATTTATCTTCTTTCTTCTTCGCCTCTGGCCCAC GCCGGGGCGGATGTTGGGGCGCGGAGTGTGGGCTCTGCGGCGCCGCGTTCGCCTTCACTGACCCGCGCGG CCGGGCTGGGTCCCCGGGCTCCCGGTCGCCCCGCCCGCCGGTGCCCCCCAGCCCGGCTCTCAGTTTGGGG GAGGGGTTGCGTAAGAAGCCGCCGCGCCCGGGGGGACTGAACTTTCCTTTTGCTTTGCGGAGTTGAAGTT TGGAAAGCTTGGGGGCGGAGAGCGGGACGCGGGTGGGGGGCTCTTACATTTCTCCCCGCCGCACAGCGAG CGGGGTCTCTGGGGAATCGAGTGATTAATCCACTCTTTCTCCGAGAGTTGGAGGCGAGAATTATCTGTCC TCTTCCAGAAAGTGCGGCTCTGTGTCACACCCCCCTCCCCCGTTTCTCAGCCCCGGTAAGATGGGGAGGG AGGGGCTTGAGTAATTGATCCCTTCTCGAGATGGGGTCGAATTCCTTCCGAATGGGGGACCTTCATCCCC CTCCTGTGGGTGTATGGGGGCTGCCCTGGAGATGCGCGCCCGCGGAGGCAGGTATTGGGTGTCGGCGGAG GCGGGGCCGCGTCCCCAGGGTGCTGTCCCGGTGCCCCTGGAGGCGGCCCCGACTCCACAATGGGCCGCTC TGATTCTGAGGCGGAGGCCGGCGCTTTGTTGGCGGGCGGGGTAGCGGGCGAGCAGCTGTCGCATTTTCCC ACGGGCGGGAGCTGAGTGTGGCCACCCCCCCTCCCCCCGTCCAGCTCTGCCCCCTTGCAGAACGGGTTTG AACAGAGGCAATCTCGGCGGCTGGATGGGGGGCCCTGCCCTGCCAGACTCCTCAGTGAGCCTCCAGGGTG GGGGGCAACGCTTTGGAGAGTAGCCCACTTTGTCTCTGCTTTTCCCCCACTGCGTCCAGGCGGCACATCA GGCCACCCCACCCTGCTTCAAGCAGGACGTGTTCCCTGCTGCTCCCCTTCCCCCCATTTCTGACTACAGA ACTCTGGGCAGAATGTTGACGCCCCTTTGGTTTCATGGAGGGGCTTCCTGCGGACCCGTGCCCCAGCAAC CCATGATACTGAGCAGAGTGCGTCCGGGGTAGGGGGCGGACGATGCCCCTTGGCTGGGTGCAGGTCCCCG CCCCCAGGGTAACCAGGGCCTTCGGTGGTGGTGGTGCGGGTGAGACTGACCTCTCTTCTCCTGCCCCTGC CTAGGCCCGCGATGCTCCCAGCCCGGTGAGACCTGCCTGAATGGCGGGAAGTGTGAAGCGGCCAATGGCA CGGAGGCCTGCGTGTGAGTACCACCCCTGCGGGACCTGTTGCTTTGTCGAGGGCAGAGCCCCTGCCTTCT GCAGCCGCGCAGGGGACAGAACACTAGGCCATTGTCTTCTGGAGATGGCCCAGAGTCTGGGCACGGTCAC GTGCTGACTTTTATTGGACAAAGTCTGGCAATTACTTAATCACCAGCAATTATGCTGCGTGTGGAGCTGG TCTGGCTGCTGAGGGCTTGGGCACTCCTCCGTGGGCCACCTCAGGCTCCGGGGTCACTAAGTGGGAGTCC CAGTACCCCAATTCTTCTTTAAGTCCCCAAGAAACAGTTGATCTGCCAGGGGAAGCTCTGGACCATTTAC TGAGAGGCCCAGCCCCCACCACCCTGCCAACTTGGGGCGCCTCCTCTGGGCGGGTGATGCCTCCTGGGCA CAGGTGATGCCTCCTCTCGGGGGTGATGCCTCCTAGGTGGGTGGTGATGCCTCTTGGGCTGGTAGTGATG CCTCCTCTGGCACAGGTGATGCCACCTCCTGGGCGGGTGATGCCTCCTCTGGGTGCGTGATGCCTCCTGG GCTGGCGGCAATGCCTCCTCTGGGCACAGGTGATGCCACCTCCTGGGCGGGTGATGCCTCCTCTGGGTGC GTGATGCCTCCTCTGGGCACGGGTGATGCCACCTCCTGGGTGGGTGATGCCTCCTCTGGGTGGTGATACC TCCTCTAGGTGGGTGATGCCTCCTCTGGGTGGTGATACCTCCTCTAGGCGGGTGATGCCTCCTCTAGGCA CAGGTGATACTTCCTGGGCAGGTGATGCCACCTCCGGGTGGGTGATGCCTCTTCAAAGGAAATTGACTCT TCAAAATCGGACCCGCCTTTGGGCTCTCTGTTTGCCCCAGCTCCCTCTTCCCGGCCTCAGGCTGGGGCTG GGGAAGAGAAGGTGGAACTCATGTTTTGGCGTGGGGTGTGGGGTAATTATTGAGTCTGGTTTCTGTCCTG GCATCTGCAAACTCTGACCTCAAAATCCCGTGGCCCTTCTGGTCTGCCAGCCTCAGATGTAAAATGGGCA CTGAGGGGGCCGGGAAGTCGTGCGGAACCGCTCCCTCCTGCCTGCCTGTGAGTGCCCATCAGCCGTGGGG AACTGTTCTGCTGTGGCCGATGCCCTTCAACTTGAGTCCATCCCTGATGAGAATAATGAGGAGGTGTTTG GTGTCTGGAAAAAGAGTTCCCTCCGCCCCCCAGGAGCTACAGATGAAGAAATGGCTCCCCAGCCAGTCTG CGCGCCCTCATTCCAACTGCAGAAGGTCCCATTCCCTTGACAACCCCAGCCCGGCTCCTGCCTGTGCCGA CTGCCCAGCCTGTGGGCAGCAGGCCCCCTCCCTCCCCGGCCCCCACCCTCCCCAAACTGAAGCCAATTAA GCAGGTCTGTGAGCAGTTTAATGGACAAAGCCGATTGTGTCTTTGTCAGACACTAATGAATGCGCACTAC TTTTTTTTTTTTTTTTTTTTTTGCTTTTTGGGGCCCCCTTCTCCCTCTGCAGAAGCCGCACGGACGCTTG ATGCCCTAAATCTTGTTTCCTTTCATTCAGAGACCGACAGCTGGGATCCAGGGGAAGTGCAGCAGCTATT GTTGGGGGAGGCGGATTAATGCCGTGTGATTAATTATGCGTGGCTTCCCAGAATGTATAACCCCCTTCCC CGCCACTGCGCTCCCGGCTCGGACTTTGCCTCTCACCCATTCGGGGCTCTGGGAGAAGCTTCTTGCTCCT GCAGAGGACTTTGGGAGGGTGGGAGGAACACCGTGCTGGGAAAATTGGGGGCCTGTTGCTTCTTCTCAGT GGCACCAGGGAGTAGGCACAGCCTGGCCCACAGGGGTCTGGGACTGAGGTCTCCCTGGGCCAGAGCGCTG TGCTTTGGGGTACAGATTGCTGCAGCTCCCTGGTGTCTGGGTTAAAACCCTGCCACAGGGCCGCAAAACA CTGGTGTCATGGGCCCACTTTCCCATTCCCCAAACCTGGGATCCCGGTGAGCTGTTTCCAGCCCAAGGCA GGCCGCCGACCATGGCTTTGGTGCCTGGCCTTGTCCCCTTTGCTGGGGCCTGGCGCCCCCTCCTTCTTGG CGGGAAGCCTGCTTCAGTTTGGCCTGACAGGCAGCCGAGCTCAGCCCACAGAGACCCCATTGTGCACACC CCACAAGTCCAACGAGAAGATGGGACGGAAGCGCGTCCTCAGGCTCCTGCTTCTGGGCCGCAGAGTTGGA GGCCAGGGCCACAGCCGAGCCCGGCTTGTGGAGGCACAGGTCAGGGCTCACACAGCAGTCTGGGGGACAT TGCAGCCGCTTCGGAGAAGGCCCCGGGCTCCCTCCCTGGGCTTGAGCCCCACCCAACATACACCCCTCAG GTGCCTCTGCCTTCCCGTTCCTGCCCATCCTTCTCAGAAGGCCCAGGAGGTCTGTCCAGGAGTTAGCCAG GGCACCTGCAGGAGGCCTGGCTCCCCCAGCAAGGGGAGAAACCCACACTGTTTCTCGAAAGAGTCTGGGG TGCAGGCTCTTGGAGCCCTGCCAGCCTGAGTGGGAATCCTGGCCCCGTGGTATCCAGCTGTGACCCCGGA AAGAGCTTTGGCTTTTGGTGCCATTTGCTGCCTCCGCTGTAGAAGGGGCATGGTCATGATGGGCGTCACA GTGCCTGGCTCACTAGTACTGGGTGAATCATTTCTTTCCATCCCAAAGAGAAGGAACCTTCACCGGAAGC TGCCAATCAGGTGGTTGCAGGGCCCGGGATTGGAAAAAGTGGTTTTGTTGGTGCAAAATGCCTTCCCAGG AGGTCAGAGTGTCGCCGTGGCCTGGTCAGCCAGTGGCCAGGTAGAAAGCACCTGGCAGCACATGCTGGTG GGCGGAGGATGGTTGGTCTCTGGGCAGCTGCTGTGCGAGGTGTGGCCGTGGTGGCTGTGGTCGGAGATGG TGGCCTTCTGAGCAGGCCCAGGGGGTCACTGTGGCCCTTGGCTCTTCTCTAGCCCCCTCATCAGCTCCGT CAGTGTGAGCAAGGGGTACTGAAGAGGGCTCCACCTTTTTTCTCTTTGTTTTGAGGAGAGCTGGGAAGAG CTGCAGGGACCCTATCTGTCTGGGTGAGACTACGTCCTTGGTCTGAAACGCTCTCCCAGGGCTGCCTGCG TCTGGGCTGGGCGTTGAGGCAGGGGGCAGCTAAGATGTTGGCTGCTGACGGCAGAGTCAGAATGGCACGG GGCGTCTTCCAGGAGCTGGGAGAAATGGGGGTAGGCTGTCACACCCAGCACCTCCAGGAGGATGTCCAGC TGCCTGCTGGGTGGTGCGCTTTAGCTTTGGACAACCTCGTGTCTGAGGCCTGGCCTGGCCACTAGCTCTG TGACCTTGGGTCATCAGGTCATGCAAGCCTCAGTTTCCCCAGCATGTCAGCCGGGCTGATACACGCTGGA TCTCTTGGTGGTGTGTGAGGATTGCATGAGAACCGTGTGGAGAGGGCACCTGGTCAGCGCTCCTTTCTTC CCCGCCTTCTCCCCGTTGGCTGACAGTGCTGGTTTCCAGAGCCTCCTTCCTGAATGTTTAATTGATTGAC GAGTGAATTCAGAGAATCCTAAAGGTGCTGCCTGGTGGGCTGGGCCTGGCACTGCCTGGGGAGGGACTTG CCGGCTCTGGGGAAGTCCATCTCCCAGGATGGCTCCAGCTCCGGGGAAGTCCATCTCCCAGGGTGGCTCC AGTTCACAGACACGTTTGAGCGCCTGCTGTGTGCTGCGTTCTGCTCCAGGCCAGGCCCCCGGTGGGGACA GGGCAGACATGGCCCCTGCTCCTGTGGAGTTCACTTCCCAGCAAGGCGTGAGAGAGGCACCTAGCTCACA TGTGGGACATGTTGGGGGTGTGCCGGCCCGGTGGTGGCCTGGCATAGCTCCCGGCAGCCCCGTAAAGCTG TCTGGATCAGGCACCGATAAGTGAGAAGAAGAGACCCAGAGAAGTCGCCATCAGCCCCAGGGTCACACAG CAGTGGCAGAATTCCTACTAGCCCTGCCCCTCTCCTTCTCCCAAGCGAATGTCCCTAAACACAGCCCCAG CCAGCCTGAGCTGCCCCGTCATTTCCCGACTACAAGCGGACTGGGGGCGTGGCTTCCCCTTAAAAGAAGA GGAAGGAGGCTCAGGCGGGAAGTGACTTGGCCCTGCAGCCGGCCTGGGAGGCTGGGGAGGGACGGGGTAG CTCCTGTCACCCGGTCTGGCTCTTTCCATTGAGTCACCTGCCTCGTCTTGGGCGTGGCCAGGGGAGGAAC AGGTTGATTCTCCTCCTCATGCTGAGCTGAGCGGAAAGGCCTGTGACAGGACCTCCTGTTTATGCAGAAC CTGGTCTTCAAGGGCGCCAGGGTTAGAAAAACATGTTTAAAAACATGCAGCATCCGAGGTGGGCAGATCA CCTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGCGAAACCCCCGTCTCTACTAAAAATACAAAA ATTACCCAGGCGCAGTGGCGTGTGCCTGTAATCCCAGCTACTTGGGAAGCTGAGGCAGGAGGATCCTTTG AACCCAGGAGACGGAGGCTGCAGTGAGCTGAGATCGTGCCACTGCACTCCAGCCTGGGTGACAAAGTGAG ACTCTGTCTCAAAAAAACAAAAAACAACAAAAAAAACCCCACACAGTGTCAAATAGAAAGTCTCACCTAC TCAGACTGGGGAGACATCAGGAACAGGAAGGCCTGGGGCGGAGACTGGGGTGGGAGCCTGGAGTGCTCTG AAGGAAGCTGGCTCCTTGGGGCAGGCCCTGCCTCTGAACAGCAGCCAACATGTTTTCCATTGAAAAGAAT AATAATAGAAAAAGAGAGAGGGAGAAAGAAAACAGCAACCCTGGCAGGAAGAGGGTAGGGCAGGGCAGAC AGTGCACCAGGGGAAGTGCTTCCACAGGGCAGAGCTGGGTGCGGGGACCCCCAGATGCGGGCGGCAAACT GGAGACCCCACAGGAGCCGGGACTGGCTTCATTCCTCATTCCCTGCACCTGTGATGGGCAGCAGCGGCCA CCGGTGCCCACTGGGCAGTTCCAGGCCGGGCCGAGGGACTGCACCCTTTTGCTGTGGGGAGGGGACCTTT CCTGTTTCATGTCTCGTCTATAAATAGTGAAAGGATGTGGCTTTGCAGAATCGATTGGGCGTCTAGCTTG CCTTCCTCAATAATGCAGCGATGACAGCTCCACACTCAGGACGCCGCTGTTACCCAGCCTCGTAAAAGCC CTGGCAGACGGCCGCCCACCCTCCAGGTGTGCCAGTGCAGTTTTCATCCCCAGCGCACAGGTGGGAAAGC TGTGGCTGCGAGGGCGTGGGGATCTGAGGCAGGCTGGCGTCAGCTTTCACCTTCATGTGCAGGCATATCC AGAACTTTCCGGATCTTTCCCCGGGCTGAGGAGGAAATACCAGCAGCTTTAACGAGCGGCTGGCTTTGGG GCATCACACCTGTGGGCCGGGCTGCGTTTGACGGCCTCGAGTTTCCCAGGCAGCGCTGGCGCTTTCTCCT GTGGGGCCCGGAGCTCCGAGGGGCTGTGAAGCAGGGCTGGCTCTGATTTGCTGTGCTCCCCACACTGTCC CCTCCCTGGGCCTCAGTTTCCCCATCTGTATGTGATTCCCCTTCCAACTACAGCCAGCGGGACCCTGGGG CGGGCTGAAGGCGTGGTGGTGGCTGTGGGCCCTGCGGCGAGGCCTGCGCTGGGCTCGGTGGTCGCCCCAG CTGGGGAAGGGGCAGTGGCTGCAGGGGTGGGAGGGTGGAGGGAAGCCCTTTTCCAAAGTTGCCTGGTTGG GTTCTCCTTGTGGCCCTGCCCCACCCCACCCTGCTCCCTGGGAGCAAAGGGAGCTAAGGACTGGTTTGGG GATGGATATGTATATGGAGGGATTCTGGGTGATGACTTATTCATATTACAAAATTTGCCTTTTTTTGTTT GTTTTTTGAGATGGAGTCTTGCTTTGTCACCCAGACTGGATTAGAGTGACGCAGTCTTGGCTCACTGTAA CCTCTGCCTCCCAGATTCACGCGATGCTCCTGAGTAGCTGGGACTACAGGCACATACCACCACTCCCAGC TAATTTTTGTATTCTTAGTAGGGGCAGGGTTTCACCATATTGGTCAGGCTGGTCTCAAACTCCTAACCTC AGGTGATCCACCTGCCTTGGCCTCTCAAAGTGCTGGGATTACAGGCGTGAGCCACTGTGCATGGCCACTT TTTTGTTTTTTGAGATGGGGTCTCACCCTGTCACACAGGCTGGAGTGAAGTGGTGGGATCACGGCTGACT GCAGCCTCAAACTCCTGGGCTCAAGCGATCCTCCTGCCTCCGCCTCCAGAGTAGCTGGGACCACAGGTGT GCACCACCATGCCTAGCTAATTTTAAATTTTTTTGCAGAAGCGGGGTCTTGCTATGTTGTCCAGGCTGAA AATGTGACTTTTGAACTAAAGCATGCTGTTGCTTGACATCTAGTCCATTCACAAGTTCATTCAACCACTA TCTAGTTCCGGGACTTTCTCACTGCACAAAACAGAAACTGTACCCAAATACTGTCACTCTGCCCTGACTG CCCCAGCCCCTGGCAACCACTAACCCGCTTTCTGCCTCTGAATTCGCCTCTTCTGGACGTTGCCTATGAA TGGAATTGTGCCATAGGTGGTCTTTTGCCCCTGGCTTCTTTCACTGAGCGTGATGTGTTTAAGGTTCATC CATGTCACGCGTGGACTAGAACTGCATTCTTCTGAGGACTACATTTTAGCCTCCAGAAGCATCAGGGACT GGCCAGAGGTGGACCCCAGCATCCCAGCTCCCAGACAGTCCAGAGGAGGCAGGTGTTGGGAGGGCGTCCG GGGTGGCTTCCTGGAAGAGATGGCGCTCACTCTGGGCCGGTGCAGCCACCCGACAGCCACAGAGCCCCCT AGAGGGAGTCCTGGCATATTCCCAGGTGAACCTGTAGGATGGACTGGCGTGCCCGCGGCCCCTGTCCTGC TCAGGACTCCGAGACAGGCTCACAACCTGTCCCTGGGCCTCACTCATGCCAGCCGCCAAGCTGTTCAGCA TCCCTTAGCCCCCAGGAGGCACACAGTGGGGCCGCGGTCACTGAGCGTCCACACGCCTGGTGCTGTAAGA ATGCAAAGTAGAGGGTCTTTATTGAGCATCTACTACATGCTGAACCCTGGGGTATGGGTGGGCACGGCAG ATGCAGGCCCCCCTGGGCAGGGGAGGAGCATGCCCCTTAAGAACCAGGCCACAGGATGGACGGGCTTGGC CACAAGCTAGGGGTAGTCACTGCAGCCTTCATGGCCTCCTGTGTGCAAAGTCAGTGCTGTGGGACCCCAT CTGGGTGCACCTGCTGTGGCTTTCAAGTGAGGCCCACCACGGAGCAGCTTCCACGCTGGCTGGGACAGGG TCAGCGGCAGGGAGCTCCAGACCAAAGGAGCGGCGGTGGCTGGGGCAGCGGGGGGCAGTGAGGCTTTGGA CACATCCATGGGGCGGGCAGGCATCTCAGCCCCCACCCGCCCAGTCTGCCTGCTCCGGGGCCTTCCCTTC CCTGGACAGAGCTCTGTGTGATTGGCTCCAGGCTGCTTCTCCCCCTGGACCCTCAGGGTCAGCTTAGAGT GACTGGCTATGCCCTGGCCTAGATCCAGGCCCGTGTGACAGGAGAGAGCTAGGAACCTGGCCCCTCACTC TGAGACACAGATGGTGTCCTCTCCAAGTTGCCCTTGGGACGGGGAAGCGCCATGTCCCCTGCAGGGCACC AGGCCAGCCAGTGGCCCTTGACAGCGAGGCCCTGTCTGCAGGCAGCTGGGGGACTTCTCCCTGTCGGGAG GATGCGTGCGTGTTAGCATCGGGGTGCCTGGTTGCCCCAGGGGTGGTGCAGGGCGGTTATAGGCGGTCCT AGCATTTTGGGGTTGCTTTCAGTGTATCTCCGAGACCTGTGGAATTCTGGGAGGAGAAACTCCCCAGCAG TGTCCTCAGTGCGCCCCCCTACCCTGTACCCGTTGCTCCTGGGAGGGATCCTGAGTGCTCCCCCCCACCC ACCATGCACCCATTGCCCCAGGAGGGATCCTGAGTGCTCCCCTCTCCACCCACCCTGCACTCATTGCCCC GGGAGGGATCCTGAGTGCTCCCCCCTCCACCCACTCCCACCCTGCACCCATTGCCCCTGGGAGGGATCCT GAGTGATCCCCCCTCCACCCACCCTGCACCCATTGCCCCTGGGAGGGATCCTGAGTGCTCCCCTCTCCAC CCACCCTGCACTCATTGCCCCGGGAGGGATCCTGAGTGCTCCCCCCTCCACCCACTCCCACCCTGCACCC ATTGCCCCTGGGAGGGATCCTGAGTGCTCCCCCCGACCCACCCTGCACCCATTGCCCCAGGAGGGATCCT GAGTGCTCCCCTCTCCACCCACCCTGCACCCATTGCCCCTGGGAGGGATCCTGAGTGCTCCCCCCTCCAC CCACCATGCACCCATTGCCCCGGGAGGGATCCTGAGTGCTCCCCCCTCCACCCACTCCCACCCTGCACCC ATTGCCCCTGGGAGGGATCCTGAGTGCTCCCCGCCTACCCTGCACCCATTGCCCCTGGGAGGGAGACTTC TGTAGAGGCCTCACCTCTGAACCCCCCACTCACAGGCTCAGGGGCCCAGGGCTGGGGGCGTCCTGCCGTC TACACTCCAGATTGAGCCCGCACGGTTAAACAGGGCCCTCTCCGCACGCCCTGCCTAATGCAAAGCGGTG GCTTCGGGTGGGTCCCCAAGGGGCCTTGTGAACCCTGGGGGCCTGGCCCCTCCCACCTGGCTGCACCCGC TGGGCGGGAGATCCCATCCTCCGAGTCCTCAGCCCCTCAGCCTCAGCTGCAGCCCAGACACCAGGGCTCT GTGGGGCGGGGGTGGGGCAGCGGTTCCCTCAGGTCTGTGGGGCTGCCCTGCTGTGGTTCCTGCAATTTCC TGGAAGGAGGTCTGGGGCCTGGTGTCCAGTGGGGCCTGTGGGGACGGACTCGGGGGCTCTGTGGGGAGGG ACTGGGGGCTCTGTGGGGACGGACTTGGGGGCTCTGTGGGGAGGGACTGGGGGGCTCTGTGGGGAGGGAC TGGGGGCTCTGTGGGGAGGGACTCGGGGGCTCTGTGAGGAGGGACTGGGGGGCTCTGTGGGGAGGGACTG GGGGCTCTGTGGGGAGGGACTGGGGGCTCTGTGAGAGGGAACTGGGGGGCTCTGATGTGCTGGGCGTGCA CAGGGGAGGCTTTGCCTCTGACATCCACACCTGCAGTTCCCAGGCACACACAGCGGCCCCATCGGGGTCC TCGCAATCACAGTCTGTGAGTGGCCACTACCAAGGGCGTCTCCGGATCAGGCCAGGCCCAGATGCTGCCC GGACCCAACCCCCACAGCGCCTGCCGCCACAGTAGGGACCAATGGCCACAGAACACTCACCCGGCCTCAC TTGCACGGGGCTGTTCAGTCTGGTGGGCACCAGGTGGGCGCTGTTCTCGCCCAGTGGGAGGCCTGCCAGC TCCTTGGTTGCTAGTTGAGATTTTTCCCCAAGAAATAGTCGTGTTGTTCCTTCTGCTCCGCCTGGCACTG AGGTTGGTGACACGCCCCGACCTTGCTCTAATTGGCAGATGAGAATTTGTCATCAGATGTCGACCCTGTC TACGCAGTCCCCTGGCCTCGGAGTCCATTGTGCATCTCTGAAGGGCTTGAATTGGTTGTTTAAAGCTGGG TAAATGCCCCCTTGACATTCTGTTGACACTGTCAATTTGCTGAACAAACTCTTCCACAGGTAGCACAGGA GGCCAGTCTCGCCCCAGCCTGAGCCAAGGCCCAGGGAGGCAGGTCCTGTGTGGAGTCAGCCTTTTTGTGA GTGCAGCGGCCCTGCAGGATGCACCGGGTTTGAGAAGTGGACTCCCCCGTCTCCCGCCACATCCCAAAAG CCCTCAGCCATGAGGGCAGGACGAAGCCGACGGTCGCCCTCGTGCCGAGATGACAACCGGGCACAGAGGC GGTGGCTCCCAGCTTCCTGCCCTCTTCCCCGTAGTGGGGTTACCCAGCGTGACTCATGGCCCGAGCCACA GGCACCCGCCCAGGGAGCCACGGCGGGGAGACCTGGCTTTATTAGAGATGCGTTCGTGCCTCATCAAGTC CAAAGGAGGAAACTGGCGCGTCCCTCACTTTCCCTGAAACAGGCTCCCCCACAGCCCAAGCGGTCAGGTT AAGGTGCATTTGCAGACAGATGCCCTAGTAGGAGGCTGGAGCTTTTGGCCCAGAATTTTCCCTGCTGTAG GCCCATGGTCACCGAGCCTGCCCGGGGGCTGAGGCCCTGAGGAGGTGCCATTGCCCCACCCAAGCCTCAG ACAAGTGTCCTGCCCTCGACCCTGCGGGAGGCAGCAGCTCAGGCCCTGACCCTGGCCAGAGAGGGCAGCT CTCTGAGGCTGCTGTGGCCGTGGCAGGCAGGGGCTGGGCTTGCCGGGCCGTCGAGTGGGCACAGAGACTA TCTGGGAAGGAGGTGGGCGGTGAGAGCTGACTCCCCGCAGCCGGGGGACAGATGAGCCCCGTGCCGCACA GCAGGGCCGCGTGGTGGGGCCCCCCAAGTTCCGCTCGGTTTCAGCTGTTGACGAGCGGAAACACACAGTT ACTGGAAATGAGAGGTTTGGGGGAGCCGCCAGGGGTTGAACATGTGTGGTTTCCCTGACGGCTTTTCAGT AAGAGATGCTTGAGCTCAGGCTGGGCACTGGCTGGTGCGCGGAGGGGGCTGGGCCAGAGTCCCCCCCTTG GGCCTCCACTCTCCATCCTTATAGAGGGACCTGGGTTGGTCCCAGCTCCCGGGGTGCAGCCCCTGGGTGG CCCCTCCTACTTCCCCTTCAGTGGTCAGAAGGAGGCTGGCCTCATTCCTGTCTGACGGAGAGCCAGGTGG GGAGGCCGGGCGGGGCTGAGTGTCCAGGGTCCACATGGTGGCGGGGCTCAGGCCGTGGCGAGGTCCTGTC CTGGGCCTCCAGGGTCTGGCCCAGCACAGAGCTCTGCAGCTCTCTGGTGGACGGGCCTGGCTGGGCTGTC GGCAGCCCTGGGGCCAGGTGGGCAGTGGGAATGGAGGTGGAGGCAGGTGGGTGGCTGCAGGTGACTGGAA GGCTTGGCTCCAGCCTGCAGGGGCTGCAGTCCAGGCCGGCCACCCCCACGAGACCTTCCCCCTTCCAGGT GTGGGGTGGCACTGGGTCAACAACACAGGCCACGGACTTCTTTCCCCCACGTGGGCCGTGCGACCCCGGG CCGCCACCACCTCTCTGAGCTCCCCTCCTCCTTAGGAGATGGGAAGCGGCTGGGGCCATGAAGTGTCCCC CAGGGCTCCTGACAGCCCCAGCTGCCGTCCTCGTGGCTGGGCGACTGCCGCGAATTGTTGCGCCTTCTTT TGAGTTGGCTACGGAGTCATGGCGGCTGTGGGAGGTGTAGCTGGGTCTCGGGCGGCACGCCCGGCTCCCC CGGGGATGTGTCATCTGTGTCATCCACCCTGGAGCCCCTTCCTGGTGCTGTGGGGGCCCCTCCAGGAAGG TCTCTCCCAGAGGCCAGCCACAGGCTCTGGGGAGACTGTGTGGGATTTGCATGCAGTTGTGTGCTATTTG ATCGAGGTCATGTGTGGGATTTGGGCGAGGTCCTGCGGGATTGGGTGAGGTAGTGCGAGATCTTTGGGCG AGGCCGCGAGGCACTGGGCGAGGCTGGGCATTATTCAGTGCCTTGGAGGGGCAGAAGTTTTAGGACCTGC CAAGTCCAGCCCAAGAATCCCCAACTTTCCCCACAGGGAAAGGTACCCCAGACAGTCCCCAGCCTGTGCC AGCTGTCTTGGGACACCCTGGTGTCCCCCAGGTTGTGGCACTGCAGGCCCCTCCCCCAGGTGCCCCTCCT TATGGGCCCCTCCCAGGGCTGCAGGCACCTGCCTGGATCCCACTTCCCAAGTGTGGGGTAATCCCAGGCG CCCGGTGATCACGCTGGGCCCGGGCAGAGTGAGGCTCTGAGGGGGTGCCAGGGGCACAGTGGGCCAGTAT GTGAGCCGGGCTGGGCGCTGGGACTGGGCCGGCAGGCGAGCGGTGTTCCGAGAGGAGGATTCCTGGGCTC GGAGGCCCCTCTGTGCCTCGTGTGGTCAGAGAGCAGGGAGCCGGCGGGTGTGATGGGGATGAGGTGACCT CTGGGGCCACCACTGAAGCCGCCGTCCATCTGCGGCCGAATCGGGAGGCACACAGAGGTGTCCTGGTGGT TTCCCGGGACAGGCGGGAGGAGGCGCAGGAGGGCGGCGTCTGCCCCCGGGATGCCAGGAGTGCTCCTCCG GCAGCGTGGGCTTCGGCTTCGTCCCTCTTTCACCAGTGCCGACGCCCCGCGGGTGCTGTGGGTGAAGGGG CATCGGTGCCCTCCTGCTGGGCGGGAGGAAGGAAGGGGAGCGGGAGGCTGGGTCTCTCTCGCCCAGGGCT CTGCCCCCACCACCCTAGGGTTTTGTGTTTCGGTGGAGCTGTAAGAATGCTTTGTCTGCTCCAGACTTCC CGGTCCTGGGAGATCAGGTGGTCAGGCAAAACATCCAGACCGTCTGGGTGGGGCTGGGGGTGCGGGGGAC ACGCGCCTTCCTCCTCTTTCCCAGGGAGCTTCTGCCACTCCTGTGCCACCCTGGGGAGCTGCCTTGCCCT GCCCCGCTCTGGTCCCCATCAGCAGGTGTGGTTCTGAGCTGCCTTCAGATCCGGGTGGTGTGCTGGGCAT AGCTGCCCCGTTTTCTCACCTGTGAAATGGGCCCATTACACGCCCCCAGGGCGGTTGTGGGGGTCCCATG AGACAGAGCTTGGAAAGCCCGAGTGTAGGTCAGGCCAGGAGGGTTGTGGGCTCAGTTTCTTCACTGCTGG GCTGGTGTGTGCCGGACAGATGTCTCGGGATCCCTTCCCTCCCTGCAGCATTCTTAACAAGGACGCTGGA CATGGAGTCAGCACCTCCGGGCGACTGCCCTGCTGGCTGTGGGGCTCACTCCAGAGGAGAACAGGAGCCC CTCCGGGGAGCCCCTTCCTGCCACCCCCAGCGACAGGATCTGTTCAGGAGCAGTGGTGGGAGGTTGCCAG AAGCATGTCTGGCGCTGGCCCGGAGCGCAGCCTGTGATGCCCGACTTCATTCATGGAGTGTGGTTTGAGC CCTCCAGCAGCGCTGCTGTGGGCCTGTCCATTGCCTTCCCTGCCTCTGAGCCATCGTGGGGTGCAGGGCT GGGCTGGGTCTTCTTGGGAGCAGAGCCCCGGCGTGTCATGACCATCTTGGCCTCTCCAACTCAAGAGGTT TGTCCACATGGGTCCCTAGGGGCCGTTGGGGTGACCCAGGGCAGGAGACACATGCCTGCTTTTGGGGGAT CCGCGTGGGAAATTCCCGCAGTGGAGCAGCAGGTGGGGCTCCAGCAGGCGTTTTTCACACTCCAAACAGC CTGCGGGGGCACTTTGGTGACACCTAGTTCCTGGGGTCTCAGAGCCTGCTGGGCTGTGTCTTGGCATTTT GGGGAGGGGCTGGCCACATGCCCCCAGAGTGGCCACCCCAGCTCCGCCATCTCCACGGGCCTTCTGTCGG TCAGATGCAGACAGCCGTTCCCATGTCGGGTGAGGGCATTGTTTTCCCGGCTGCGGGAAAGGTAGCTTCC CGGGAGGACAGGTTCTGTCCCCATCCCGCCTCCCACACAAAGGGTTTCCCCGGAGCCAGAGGAGGAAACC TGGCCTTCCTGCACTTCCTCCTTCGCACATTTTAAACCATCCGAGGATGCAACTGGGGGAAAAGATTTGC AGACAAAAGAGCTGGGGGTGCCGGCAACAGCTGTTTGGGCCGGAAAGCCTGGCCCCGGCTCAGACCCCGG CTGGGTCCCTGCGCTGTGGCGGGCCGGCCGCGACCCCCGCCCCACCCAACTCCGCCCCCTGCTGCCCGCT GTCTCCGGAGCGGCGGCTGTTTGGGGCTGGCTCCTTTTCTGGGCCCCCACCTCCCTGAAGCCCCCACTGC CCCTTTCCTCCTTCCTGGGGCCCTGGGAGCCAGGGCAGGGCCCCCGTGCAGCTTTCAGCAGCTCCAGCCC AACGGCTGCAGGCGCTGGGGAAGACCACAGCTCAGGTGGGACCGCAGGTGGTGGCTGGAGGCAGCCATCC CACATCGCAGCCCCCAATCTCGTGGTTTTGTGCTCCAACGGTGAACAGGCCTGGTGGTGCTGGGCTGTCG TGGGCCCCTTGGCCCCCTCGGTGCCTGCATCCCTCTCTCCTGTCCAAGATGGGGAAGGAAGCCGGGAGCA GAAAGGGAAGAAAGACCCAGCGGCTGCAGGGCGCCTTTCAGGGCCTCCTAGCCACCGCAGAGGCTCCAGC CAGCTGTTTGAACAGGGGTTGGGACACAGGGTCCTGGCAGGTTTGAGGAGCCCGGGGCCTTCCTTGCTAT AGCTCTTTGTTCTGGGGGATTTGGGGAGGCCAGGGAAGGGGCTGTGAGCAACGAGGTTCCAGCATCTTCC CAAGCCTCCTCCATCCCCCAGGGCTGGGCTGCTTGGCCGTTCCAGTGGGAGAGGACCCGAGGTGGGACCC CGAGCCCCCTGCCCAGCTCATTTCTTAGCAGCCGGTGCCTCCTGGAAGGTGGGTGGTGCCCACTGGGATT GGGGAAACTTGGTCTAGCCTCTACCCAAGGGAGGGGCTGAGGTCCCAGGACTCCCCCTGCCCCAGAAGCC TTGGTCCGGGCTAGAGCTGGGCTCGTTGGCCTCATGGAAGCCTGCCTTGGGAAGCATCCCCACCCAGGTC TGGCCTTGTCTCCCCGTCTCCAGTAGGGGGTCACAGTGTCCCCCCAGCCAGTCCACATATGGCCCCATTT GCTTGGGCAGGCCGATGGGTGGGCCTGTCTGTGTGGCCCAGGTCACCTGGTGGGGCCCACTGTCAGTGGC GTAGGTAGAAGGTGGTCAGCCTTGCTGGGTCTTAGCAGAGCACGGCAGGATCTGGGTCTGGGGAGGGCGT GGGGGTGCCCCTGCCATCACAGGAGCAGGCAGAGTGGGAGCCCTAGACTCCCCTCTGGGCAGAAAGCCCC TTGAGGCTGGGGGCAGGTCCTGCTGGTGAGGGAGGGGTCCCAGGGGCAGGGGCACCCTCAGGCTGGCCGC CTAGCGATTGGCTCCTGCAGGACGTGGCCACGGGCTCCCTGGGAGCAGCAGCTGTTGGGGGTGTCTGGGG AGAAGACCCCCATTTATTGCCCTGTGAGGGACCACACTGCTGCCAGGGGACCCTTGGGCTTCTGTGGCAG GACAGTGGGCCGGGATTGGCAGTGAGGCCCAAGGAGGGCAGGTGGGGCTGGACCTGTGGCTCTGCTGGGG AGCAGGTGGGATGTGTTAAGATGCTGATTTCAGCCGGGCAGCTCCTCCCCTTCCCTTCCCAGGGAGCCGG GGTGTGCAGGGCCGTTCCTTCCCCTCTGGGAAGTGCAGCTCCTGTGCACCGGAGAGGCCCCCGCACTGTC CCTGCCCGTCCCACCAACTGTCCCTGCCCGTCCCTCCACTGTCCCTGCCCATCCCCCTCACTGTCCCTGC CCATTCCCCGCACTGTCCCTGCTCATCCCCAACACTGTCCCTGCCCATCCCCCCCTCACCGTCCCTGCCC ATCCCCCCCGCACTGTCCCTGCCCATCCCCCCCCACTGTCCCTGCCCATCCTTGCCTTGGGAGGTGCTGT CACCTGGTGGAGCCATGGGAAGCACCTCTCCCACCCAGGGTCTCTGGTTCCTGTGGCGGGTGCAGAGCCA GCCACATCACTGACACCCCAGCTGGGTTGGGTCCAGCTGACCCCACACCCCCACCCCTCTGCTCGGCCTC TGCCTGTGCCCCCATCCCTGGCCCTGCATGACCATAAACTCCTTGAGGGCAGGAAGTGAGTGAGTCCTAC CCGCACTGAGTCCCTCTCACCCCTCCTTCTCATTTTGGGGCGGAGGGAACTGTCTTCTGTCCCCTGGGGG TGGCAGATGGCCGCTTAGCTTAGAAAGGAAAACAGCACAATTTAGAATTCGTCCTGGGTGAAAGGTCTCG GCAGCATCTGCCTCCTGCTGCTTTCTGGAGTCGCATTTCCATGGAGCGGCCCTGGCAGGGAGGGTGGGAG TGGCACAGTGGAAATACTGAGGCGGGAACAAAGTGGTGGCGGTAGAGGTGGCGGGAGCGGCACAGCAGGC GCCGGGGCCACTTGGCACCCTCCCCCCGCAGCCCTCCTGGAGTCCCCGCCCGCCGCTCACCTGCGGGGGG CCCAGATAGGACAGGTTACCCCAGCGCCGCCAGGCCACTGAGCGTGGGGGATGGGACAGGCAGGTGCCGG GTGACCCTAAGAGGGACGCACGGAAGGGGAGTCCACGGGGGCACACCTGGCGTGGGTTGGGTCTCCTCCG TGGGAGCCCGAGAGCTGGGTGGCTTGGTGGACAGGGCAGCTCTCTCGTCCAGTCGGGGGAGACTGGCGTT CCCTATCTCAAGCCTCACTTTTTAGCCCCAGAGGGGTCTCCCCACCGCCCCTGATAGGAGGAGATGCGGG GACGGTGGAAGGTGGGGTGCGGGTCACTCATGGAAGCCCTGAGGATCCCCGTGGGCGCGGCAGCTGTTGG GTGCCACCTCACTCGGCCAAGCCCTGGCGCCCACCTCGCGGCCCACACCCACCTGGCCGCCGGGACAGCA TTGAAGACAGAGTGGCCCGGGTACCGGGGGTGTGGCCAGCGCCAAAGCTGTGAAGGATTTGCTCACAGGC TGGTGGTCCTGGCCATGGCCATGCTGCAGGCCTGAGGTCCCTCCCACCTTCTCAGGGACGTCTGGGTGCT GTGCGGAGGGCAGGTGTTCGCCGTCTGTAGGGTGCTCCAGCTCTGTGGCCATGTGGGAGAGAGGTACAGA CTGGGGCGGGCACAGGCTGGAGGCTGCCCACAGCAGCAGCGGGAGACTGGGCCCAAAGCTGCCCCCCACA CACAGACCCCCACACCTGGCTCAAAACTTTCTCCAGGCTCGGCCCGGTTCCCCCCAGCTAGCGCGTCTCA CGGAACCTCCAAGCCGTGGCTGTGGGGCCGTGGCAGGGGCCTTCCCTGTGGTGTCCGATGCCCAGGCTGG GAGTGGGGGCGGACAATGGGCCCTCTCAGCCTGCATTCCCCCACGGGAGCCTCCTCAGGCCTCCGGCTGG GGCTCCTGCCCCACCCGCTGGGAGCAGCTGCCGCCACGTCTGACACCTGCTCCCAGCCGCCCTTTGTCCG AGCACCGACGCCTGATTTATGGGGCGTGTTTTCCTCTTGCTGGCCCGGCGTGATACAGCCTCGTTAACTG GGATGCGTCCGGTTGGGCAGATTCTCCCACAGTCCTCCACGTTGGGGTCCGCGCTCAGGGTGGGGAGTGG GGCCCGGTGTCCGGGCAGAGTGTCGTGGTCCATTCAGGGACAGCCAATGTCCTGTGACCTCAGGGCACTT GGTGGGAGACTGCTCTAGGGGCTCGGACCTCCAGCGTCTCCCCTCTGGGGTCCCCTAAAGCTGTGGGATG GGCCTCCCCTGCCCCTCCTCCCCGTCTTGCCCAGCAGGTGAGCTTTTCCCGCTCCTTGGAGCCTCGAGGG GCCGGGAGGCAGGGGACCAGCTTGCATGGGCCAGGCTGAGGAGCCTCCAGCCCCGGCTTTGATGACCGAG CGCCCTCTGTCCTGTACCCACCCCCTGCCGACTTCAGCGGCTGGGAAAGCAAAAAGGGCCTTTTCTCCAA GCGGGAGCTGTGGCCAACTCCCGCCTGACAATGGGGCATTTATGTGGAGGGAGGGCGCCCCTCCTGTGGC CACAGCCCAGCCCAGCCCAGCCTGTGCACTCCACGGGTTCCCAGCGGCCGCTCCACCTCGGGGACCGGCC AGCCTGTAACTGGATCTGCATGCAGTGGGAACCACGTCTGCCCTCCCAACAGGTGCCCGCAGAGGCAGGT CTGTCGCTGCAGCCCCGGAGTGACCGGCCACATGGGATGGAGGAGGGGGAGCCTCATTCCGGGGCTGTGC CCGTCGCTCACTGGGCTGGCAGGAGCCGTAGCAAGGCCTGAGTGAATTCCCCAGAGCCCCTTTGGAAGGG GTGACATGTGTTTTCTTTAAGCCAGTTGGTTTGGGACTTTTGGCTTCTGGCAACAGATGGTCGGCCAGAG TGGCCCTTTTGCGTTCTCTCTACCCAAGCCGTGGTCACGGGTAAAAGCCTTCGGGGAAGACAGATGCCTC CCGGGCCTTTGGGACAGGGGCGTGGCTGGCTGCTGAGAAACGCACAGGAACCCCCACCCCCAGCCTCCAC AAGCCCCTCGGGGTAAGGCCCCCCCAGGCCACTGCCACACATAGCACAGGTTTGATTGGAGACACTGGGG TGGGAATAAGCGGGAGAGGAGGCGAGGACTTGGGGGGCCGGTGGGGGTCCTGTGGGAAGCCGGCAGCTTC AGGGCCGGTCCTGGGGCAGGCGGCCGCCGCAGCCCCGCACCCAGGTGGGCTCCGGAAGGCGGGACGGTTC CCTCTGTACATCCCATCTGGAGGAGGCCATGCCCACCCAGGGCCTGAGCCGTGAGGCTGCTGCCTTCCCG GGCCGCTGGGGCCGCTGAGGCTGGTGGCATGTTCTGCTTCAGAGGCTTCACCACTGGGAAGAGCGGCGCC CGGCGGGTCCCAGACCTTTTCCCGGAGCGCAAGGCCAGGAGGTGACTGGGGCCGGAGATTTATGACCACA GCAGGTGGCTGGGGGGGGCAGGCTCTGCGCCTGTTGCCGCAGGGAACAGGTGAGACCAGGCCTGGGTGGA GATGCAGGACCCCTCCCCTGGCTCCCCTTGTTCTCTCTGAGCCCAGACTGTGTGTCCGGGGTGAGGGGCA GCCTTTCACCCACCTTGACGGGGTTGCAGAGACCTGGCAGAGGGACCTCCTCCTGGCACCTTGGTTTCCC CGGCTGTAATGTGGGTGCTTCTGCTCCTGGCTGATGTGCCTGGATGTGAGTTATGAAGACTCAATGCCGA AAGGGAAACGTGTCTGGGGGCTGAGCGTGGGCAGGGAACGGGCCAGCCTTCATCCCCAGTGCGATCTTGA CATGAGATGTCCCATCCCCATTGCAGTCTCAGCCTGAGGTGTCCCATCAGAAAGGCTTCCTGGCCGGGCG CGGTGGCTTACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCAGATCACGAGGTCAAGAGATCA AGACCAGCCTGGCCAACATGGTGAAACCCTGTCTCTACTAAAAATACAAAAATTAGCTGGGCATGGTGTC AGGTGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCGCTTGAACCTGGGAGGCAGAGGTT GCAGTGAGCCTAGATCGCGCCCCTGCACTCCAGCCTGGGCAACAGAGCAAGACTCAAAAAAAAAAAAAAA AAAAAAAGAAAAGAAAAAGAAAGGCTTCCACGTAGGAAGGGGCTGATCCACACTTTCCGTGGCTGCCATC ATGTTGACACCTGAAGGTTGGAAAAACCACGGCCTTTGTTACTGCCCAAGCAATGCCTGTTCGCTTTAGC AAAGCTGGGAAGAAAAGCAGATAGGCCTGCAGACCCGGAGGCTCTACGGAGCTAATGCACCCGGCTCCTC TCCATGGCTCTCCGCGGGTGTAGACCCAGACCCCTGCCCGGGCTGTGGAGTCCAAGCTGGGTTCTGCTGG AACATCCTAGTCTCTAGCTTGTTCCCCAAGTTAGCAGTCATTTGTCTTCTTCTTTCTTTCTTTTTTTGAG TCTTGCTCTGTCACCCAGGCTGGAGTGCAGTGGCGTGATCTCGGCTCACTGCAACCTCTGCCTCCTGGGT TCAAGTGATTCTCCTGCTTCAGCCTCATTCAGTGGCATTCAGTACATTCCCAAAGTTGTGCAATCGCGGC ATGTGTCTGGTTCCAGAACATTTTATCAGCCCTAAGGGAACCCCGCTAAGCAGCCGTTGTGCCCGTGCCC GGGGTGTGGGGGGAGGCGGCTGTGCCCATGACAGGTTCCCGGTGCTGAGTGGCGGGGGCGCTGGGGAAGC AGGTGGGAACTAACTGCCCTGGCACATCTGCCAACAGCTGTGGCGGGGCCTTCGTGGGCCCGCGATGCCA GGACCCCAACCCGTGCCTCAGCACCCCCTGCAAGAACGCCGGGACATGCCACGTGGTGGACCGCAGAGGC GTGGCAGACTATGCCTGCAGCTGTGCCCTGGGCTTCTCTGGGCCCCTCTGCCTGACACCCCTGGACAATG CCTGCCTCACCAACCCCTGCCGCAACGGGGGCACCTGCGACCTGCTCACGCTGACGGAGTACAAGTGCCG CTGCCCGCCCGGCTGGTCAGGTGAGGGAGGACCCACAGCCTGAGGGGTGGGCAGACCCAGGCCCGCCGCC AGCTGCCCAGGCAACTTGAGGTACTTGGCGGGATCCAGGCCCGGGTCTCTGACCCGGAAGTAATTGGGAG CCCCTGCCCCAGGGTCCCTGCCCCCCTCCCAGACCTGGAATCGCCTCGTTTTCAGCTGCTTGCTCTGGCC CAACTCTTGCTGTCCCCGCTTCTGCGAGACAAGGGGAGCCTCTGTGTCCAGGCCGCCCCTGCCCCCTTCC TCCTGCCGTGCACTGGCCCTCACCTGTTAGGGTGAAGGGTGTCTGGAGGTGTCAGCTCTGGGAAGAGACG GCCCAGGCTCAGGCCTCTTGGGAGCTGTGGTCCTTCATCTGCCAAAGGCGACCGGTCTCACGGCAGGTCC TGAGGATCAAATGTGATAGCACCTAAGGTGGAGCCCAGGCTGGCACCTCCAGGTGGCCTGAAGGGAGGGA AGGCCCGGCCTCGGGGAGCAGTGAGGCCAGCACGACCCTCTTGTCCCCTTGTCTCCAGGGAAATCGTGCC AGCAGGCTGACCCGTGCGCCTCCAACCCCTGCGCCAACGGTGGCCAGTGCCTGCCCTTCGAGGCCTCCTA CATCTGCCACTGCCCACCCAGCTTCCATGGCCCCACCTGCCGGCAGGATGTCAACGAGTGTGGCCAGAAG CCCGGGCTTTGCCGCCACGGAGGCACCTGCCACAACGAGGTCGGCTCCTACCGCTGCGTCTGCCGCGCCA CCCACACTGGCCCCAACTGCGAGCGGCCCTACGTGCCCTGCAGCCCCTCGCCCTGCCAGAACGGGGGCAC CTGCCGCCCCACGGGCGACGTCACCCACGAGTGTGCCTGCCTGCCAGGTAGTGCTGCCCGCTGGCCGGGG TGCACGAGCCCCTCCCCGGCTGCCAGGCCCAGGGGGTGGGAACGGGGCGCCTGGTGTAGGGGCAGCCCTG GGAGGGCCCATGGCGGGGAGTTGGGAAGGCGGGATGGCGAGTTCCCCAGACTGCGTGTGGTGTCGGGGGG ACGCGTCTGGAGCGGGGTGTGCGCTGGGAGGAGGCTTGCACAGGGTCCAGGTGCCAGCCCGTGTCTCTGG AGTTTCCCGGAACTCACATTCGAGCTGTAGGACGCCCTGCCTCCCCCCAGTGCAGGCACCCTGACTTGCG CAACCCCCAGGGTTTCCCCTGCAGTGGGGCTGGGGCCGGAGAGGGCGTGGGAGCTGCGGGGGCACCATCA CTTCCCAAGCCATGGCCCTTCCTGCCATCCTGCTGGTCTCCTGCGGGTGTGGGTGACAGGTAGGCGCAGC CGCCTGCCCGTGTCCCCAGTGCTCCCCGATCCCCGTGTTGTACGTAGGAGCCTCTCTGCTGTAGTTCTTG TTTGAGTAAATTTTGCAGCAGCTCTAAAAATAAGGAAGAGTTTTGAAAACCTCCAGTCTCGGCCGCGCGT GGTGGCTCACGCCTGTACTCCCAGCACTTTGGGAGGCCGAGGTGGGCAGATCACAAGGTCAGGAGATGGA GACCATCCTGGCTAACACGGCGAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCCAGGCATGGTGGC ACGCGCCTGTAGTCCCAGCTACTCAGGAGGCTGAGGGAGGAGAATCACTTGAACCCGGGAGGCGGAGGTT GCAGTGAGCCGAGATCCCGCCACTGCACTCCAGCCTGGGCGACAGAGCGAGACTCCGTCTCAAAAAAAAA AAAAAAAAAGTGAAGAGAAAAAAGAAAACCTCCAATCTCAGCTGCACAGAATGGCTGTTAGGTGGGAATG GGGAGAGGGCATTCAGGCAGGGGTGGGGCTGGAGGGTGCACAGGGTCCTGGCTGACCCACGGGTGGCCCA AGGGCTGCCCCACCCCCTTGGAAGCCCCAAGCTGGCCTGGCCCCTGCAAAGGGGAAGCTCCCTGGCTGCC CAGTCAGCTGAGCCCAGCCACCTCTGCGTGCAGACACCAGACGTGTGCGTTTCCTGCAAGTCACTGGGCG AGCGTGGGGTGGGGACAGACACTCCCTGGCCAGCTTGGATCTCTGCAGGGTGGGGCGCAGAGCCCTTCTG CTGGTGGGGGCTCAGATGCCTTCCTAGCAGCACGGGACCCTACCTCCAGTCACACGGATTGAGGGGCCAA GCTCTTGGGGGGCCGTGGTTCAGGCTAGGGCAGGTGGGGTGTGTGCGGCCTTGTCCAAGGCCACCTGTGT GCAGAGCTGATGCCCACCCGCCTTGGGCAGGGTGGGTGAGGACCTCCTGGTGAGGCCCAGCGGCAGAGAT GCCAGGGGTGCTGGGCCGGCTCAGAGCCACTGCCCGTGCAGGGGCAGCTCAGGGCCCTGGGGAGTGGGCA GGGAGGGAAGGGGAGGGGCTGGTGGGGTTCACTCACTTGAGTGTGGGTAGATCTCAGAGGCTGGGGTGCT GGGGGCTGGGTCACCCGTCCGGTGAGGGGTGTGCTCACTGCCTGCTGTGGAGTCTGGCCGTTTCAGGGTG AGATGACCATCCGGGGGCCTCCCCAAATGACTCAGGCCTGCCAGACCCCAGCTTCAGACTGTCCCCGGCG GCCCCTGCACCCAGGCCCCCTGAAGGGCCCTCAGCCACCTCTGGGTGGTCAGGAGCCCAGGAGACAGCTG TGTGTGGAGTCACGGGGAACCGAGATGGGGGCGGCCCTGAGCTCTGCAGGCCCGGGAACTGGCTGGGATT TGGGGTCGCACAGCCTGCCTGGCACGTCAGCACTGTCTCCTCGTGGGGTCGCTGGCCGAGGCTACGTCGC AGAGGGTCCAGCTGGGGTCCACGGGGCTCTCGCTGGCTTCCCGCCCTCTCCCCCACTGTGTGCCTCAGCC AGTGCTTTGCAGGGCAGCCCTGGGGTCGCAGGCCCAGCCAGGGGCCCCATCTGCCTCGGAGCCGGGGTGC AGGGCCCCACACATGAGTGGGACCGGGACTCAGGCTCCAGGCTCTGAATTTTTTTTTTTTTTTTGAGACA GGTCTCTGTCACTCAGGCTGGAGTACAGTGACGTGCCCTCAGCTCACTGCAGCCTTGACCTCCCAGGCTA AAGCGATCCTTCTGCCTCAGCCCCTCAAGTAGCTTGGGACCACAGGCCGGCGCCACCACGCTTTGCTACT TCTTGTATTTTTTTTTGTAGAGACGGGGTTTCGCCATGTTGTCCAGGCTGGTCTTGAACTCCTGGGCGCA AGCGATCCACCCACTTCAGCCTCCCAAAGTGCCGGGATTCCAGGCGTGAGCCACCGCGCCAGGGCTGGGG TCTGGTTTTGGGTGCTCCCCAAGCTGATTTGCATTTTGGATTTTGGTTGTCTCTGGCTGCCTGCTTTTGC TCCGGTCCAGCAGACAGACAGAACGGACGGGGTGGTGGCGGTGGGGCAATGTCTCAGAGGGAGGGGCCGA GCAGGTGGGAGCTCCAAGGGCAACGGGGGTTCAAAGGCATCTCGGGAGGGCGGCAATTAGTAACCGGCTG CAGGTTTGGCTGTTGCCGAACGCGCCTTTCTGGGTTGATCATTGAACCAGCGGGAGTTGAGTGGATTAAT AGCTAACTGGCTGCCTTGGAGGCCTGGGTGGGGCCATACCTCGGGGGAGGGGGCCCTGGCAGCCTGTGGA GGAGGAGGGGGAGGAGGAGGTGGGCACCAGAGCTCTGCCCCAGGGAGGATGGGCCATCTGAATCTCTGCA GCTTCCCTGGGGCTGCGAGGGGCCCACCCTGCCCCAGCCAGCAGCCTGCTGGCCCCATGTCCCCCTGCTG CTCAGAGCCCAGGCCCCAGTGTCAGCCCCTGAAGATGGGGTGTGCGGCCCCCCTGTGGAGACATTGTAGG GAGCTCTGAGCATGCAGGCGGCACCCAGGTGCAGGAGCTGCCGGAACCTCTTAAAAGAGACCCAAGGGTT TTTGTGACAGAATCTTCTGGAACCCTGTGTTCCTGAGTCCCTGTTTAGCCAGTCCTGTCCAAAATGATTC TTTCAAGCAGGGCGTGTCCCTCTGGGCACTGGAGTGAGGCAGGGGACGGGCACAGACCCCGGGGGCCCCA GGGCAGGGCCGTGGAGGCCAGGCTCTTGTGTCCAGAGCAGTGTGTCGGGGGTCCAGGCAGGAGCCGGACT GGACCTCAGGGAAGAGGCTGACCCGGCCCCTCTTGCGGCAGGCTTCACCGGCCAGAACTGTGAGGAAAAT ATCGACGATTGTCCAGGAAACAACTGCAAGAACGGGGGTGCCTGTGTGGACGGCGTGAACACCTACAACT GCCGCTGCCCGCCAGAGTGGACAGGCGCGTATACGGGTCGCCGCAGGGCGGGGTAGCCGGGGCGGGGCTG CTACCCACTTACTAAACTGCACTCACAGGCATAGCGGGGAGCAGCCGAGACCCTGTCCCAGGCCAGGCAG ACTAGGGTTGGCCGAGAAGGACAACATGATGGGGGCCCCACTTCCCGTGGCCAGGGTCTGGTGCCCCTCA CCTCGGGGGTCAGCACAGACAGGGCCCTGGTTGGTCTGTGTGGGCCGTTTGCAACCTGGCTCCAGGCAGC CCCTGTGCCCAGTGGGGTGTCCTGGCATTGAGGGCCTTCAGCACCCCACTCAGGCCACGCTTCCTGGGCC AGTCACAGGGATGCCTGGATGAACAGACAGGCCCTGTGTTCGGGAATTACCCTCTGGTGGGGTGACGGGC AAAGGTGCACCCCGACGCAGCAGTGTCCACAGAGCACAAAGAGGAGGCAAGACTCCATGGTGCTGGGCCT GCAGAGGAAGGAGTGATTTAGGCTGGCGGTGGGTGGAGGAGTCAGCCCAGGAAGGCTTCCTGGAGGGGGC GGCATTGCCACCCTGCGTCTTAGGGGACAGGGAGCTCAGGGAGTGGCAGCTGCCCGGGGCCGACAGCTCC TGTTCCCTGCAGGTCAGTACTGTACCGAGGATGTGGACGAGTGCCAGCTGATGCCAAATGCCTGCCAGAA CGGCGGGACCTGCCACAACACCCACGGTGGCTACAACTGCGTGTGTGTCAACGGCTGGACTGGTGAGGAC TGCAGCGAGAACATTGATGACTGTGCCAGCGCCGCCTGCTTCCACGGCGCCACCTGCCATGACCGTGTGG CCTCCTTCTACTGCGAGTGTCCCCATGGCCGCACAGGTGAGTGCCTTGAGGCCCAGGTGGGCGCAGGGGG CTCACATGGGCCAGGCCTGAGCTGTGTGACCTCACCCAGGGACTGTGGCCCTCCTGCACCCAGGATAACC TGAAAGGGCCTTTCTGGTCAGGGAGGCCGGTGGTCGCTGTGAGTCCCCCGGAACGTCCCAAGTGTCACGG GATGCCCGACGGGGTCACGGCGGGCAGCTCCTCCTGGGGTGTCAGTGGGGTTGGACCCCAGCCGTGGGTG GTGTGCCATGCCTGGCCCAGGGGCCGTGCCCACTGACCGCCGCTGCCTGCCCAGGTCTGCTGTGCCACCT CAACGACGCATGCATCAGCAACCCCTGTAACGAGGGCTCCAACTGCGACACCAACCCTGTCAATGGCAAG GCCATCTGCACCTGCCCCTCGGGGTACACGGGCCCGGCCTGCAGCCAGGACGTGGATGAGTGCTCGCTGG GTAGGTGCCAGCACAGGGGGTGCGGCCAGGTGGGGGTGGCAGCCTGGCCCCAGAACCGATGAGAAGTCGA TTCTGGCTTCAGGGGGTGCCCAGTTAGATGGGGGATGGGACCCTGCCAGTCCGATGGGGGTGGTGTGCAG TGAGGTGTTGCAGGGGCCAGGGTGCCTGGAGCAGCCTCTCACCCGTGTGCCCTCGCCAGGTGCCAACCCC TGCGAGCATGCGGGCAAGTGCATCAACACGCTGGGCTCCTTCGAGTGCCAGTGTCTGCAGGGCTACACGG GCCCCCGATGCGAGATCGACGTCAACGAGTGCGTCTCGAACCCGTGCCAGAACGACGCCACCTGCCTGGA CCAGATTGGGGAGTTCCAGTGCATCTGCATGCCCGGTGCGTCGGCCGGGGCCAGGGCGGGAAACCGAGTC GAGGCTGGGCAGCCTTGGAGGGGCAGCCCCGGGAACATCTGTGGGTTGCTTCCGCTTTCCCCAGCCTCCA TGCCTTCTGGGCCCACAGCCTGCACAGGGCATGGGGAAACTGAGGCCAGGCCACAGGGCCAGCAGAGCAC GGGGGCAGTGCTAGGCAGATGAGGGTGCCGGGCCAGGGGCCACGGGCTGCAGGGGAGCGGGTGCGCAGGG GGCCCGTGGTGGCTGGGACACTGGGCTGGAGGCAGGGTTCGTTTCTGTCCCAAGTCCACAGCTGTGCCCA GTGGGGCACTGGGGCCGCGCGTGCCCCCCTCACTGTTGCCCCACCCCACAGGCTACGAGGGTGTGCACTG CGAGGTCAACACAGACGAGTGTGCCAGCAGCCCCTGCCTGCACAATGGCCGCTGCCTGGACAAGATCAAT GAGTTCCAGTGCGAGTGCCCCACGGGTGAGGGCCACCCCCGCCCCCTGCCCCCGGGTCGTCTGCACCCTG GCCTCCTGAGGGGTGCCTGGGCGTGGGTTGTGTCCCCTGCCCCCGGGCCATCTGCACCCCGGCCTCCTGA GGGGTGAGGGCCGCCCCCACCCCCTGCCCTCGGGCCGTCCGCACCCCGGCCTCCTGAGGGGTGAGGGCCG TGGGTTGTGTCCCCTGCTCCTGGGCCGTCTGCACCCCGGCCTCCTGAGGGGGGCCTGGCCGTGGATTGTG TCCCCTGCCCCTGGGCCGTCTGCACCCCGGCCTCCTGAGGGGTGCCTGGCCGTAGGTTGTGTCCCCTGCC CCTGGGCCGTCTGCACCCCGGCCTTCTGAGGGGGGCCTGGCCATTGGTTGTGTTCAGATTCCCAGGAGAG CGAGGGTTTTGCCTCATGAGTGGATGGGAGTGTTTTCAGACTTCCCCGAAGGAAGGGCAGGGCCCAGTGG GGAGTGGGAGCTTGCCCAGGGGTCGCGGTGGAGCCCAGGGCCAGGAGATCCTCCTTGATCTGGGTGCAGC CCCTTCTGCCTGGAGAGAAGGGTATACCAGGAGCTGCAGTGCCCAGACAGGGAGGAGGCTCCAGCCTGGC TTTCTGAGGGCTCGATGCTGGGAGGGAGGCCAGCCTGCCCTGTCCTGCCATGTCCCCTGCCCAACGGCAC GCCAGCGACAAGGGTATGCAGAGAACCACGTGGGGCAGGTTGGCCTGCAATGGAGATGATGGCTGCCCGG GGCGGACTTGGAGGAACTCTCAGGGGCCTGGGTGAAAGGTGTTTCCATCTGTCCCAGAGCTGGGGGCCGG GGCGCAGAGCCCAGGGAGGCGTTGCCAGCCCAAGCCTAGGCTCCCAAGACATAGATTACCCGTCCCAGAC ACTGGAGCGAGGGGAGCCCCATTCTCAGCCCGGCTCCACTGTAGCCATAGCAACCCAGTCGGTTTGGGAA AAAGGCCCCTTCTGTGGGAGCGAGGGCGTGTGGTGCTGGGGGAGGGGCTTTGATCCGGGGAGCGGGCAGC GGGAGGCAGGGAGAGCTGGAGCTGGCTGAGCTCAGGCTGAGTGTGCCCTGGGGAGCCCAGCCAGGCGCTC ACTGCTGGGGTCTGGCCAGGGGTCCCTGAAGGGCCATAGTGCTGTTGCACATGACTCCCTCCCCTCCCCT CCCCGGCCCCAGGCTTCACTGGGCATCTGTGCCAGTACGATGTGGACGAGTGTGCCAGCACCCCCTGCAA GAATGGTGCCAAGTGCCTGGACGGACCCAACACTTACACCTGTGTGTGCACGGAAGGTGCGGGCTGGCGC CCACCAGCGGGGAGGGACTGGGGACGGGACAGGGCACTCAGGGCAGTGAAACTGACAAGGTCATGGACAC CTTGGTCTGGGCCACCTGGTCCAGAGGCCGAGAGCACAGCTCAGCCCCAATCCTGAGTAGGTGGGAATGC CACGCTCGGAGCCCTCCTCAGGTTGGCACAGGTGACCCCAGGTCTGGTCATGGGTGTCCCGGGGGCCGCC AGTCCTAAGTCTTCCTGTGCCCGCCCCTCCCACGGTCCAGGGTACACGGGGACGCACTGCGAGGTGGACA TCGATGAGTGCGACCCCGACCCCTGCCACTACGGCTCCTGCAAGGACGGCGTCGCCACCTTCACCTGCCT CTGCCGCCCAGGCTACACGGGCCACCACTGCGAGACCAACATCAACGAGTGCTCCAGCCAGCCCTGCCGC CACGGGGGCACCTGCCAGGACCGCGACAACGCCTACCTCTGCTTCTGCCTGAAGGGGACCACAGGTGGCC GGCCAGGCGGGTGGCCGGCGGGGGGCCAGTGGGCAGGGCGGGCCTGAGGACTGACCGACACGTGCCACCC CTTCAGGACCCAACTGCGAGATCAACCTGGATGACTGTGCCAGCAGCCCCTGCGACTCGGGCACCTGTCT GGACAAGATCGATGGCTACGAGTGTGCCTGTGAGCCGGGCTACACAGGTGAGCGGCCCTGCACGTGGGGG CTGACTGCACTGTGCTCAGAGGTCAAGGTCAGCCACTCTGCCCTGGGGCTGCTGAGGGGTTGGGTGAGGG CTTTGGTGCTGCCCACCTGGGCAGACCGTGGTCTGCAGCAGAGATTGCAGCGGGACCAGGGCTATAACTG GCAGCACGATGGGTCCCCCCGACCCCTCTTGTCTCCGGTCAGAGCTGTCCCAGGCCGTGTTGGCAGAGTG GCCCAGCAGGCCAAGAGGGAGCAGCCAGCCCTGAGGCCAGGCTTAAGTACCTTCTGCCTCTGTGGCTCAC CAGCACCTTTGAGCAGGTCCCTCTGCCTCTCTGGGCCTCAGATTCTCATCAGTCAGGGCTGCAGTAGCCC CTGCCCCTGGGGCCCCTGGGAGGATGACTTGAGTGGGCACTGGTGCCCGGGGAGGCTGGCACATGGCACA TTGTGATCCAAGATGGTTTCTGACACCTGGAAGGATGTGGCCAGAAGGGTGATCGCCCCGGCTCAACAGA CAGGGAAATCGAGGTTGACGTGGGTGGGACCCCCTGGGCGCTGGGCCTCGGAGTCTGACCCGCCCTGCCC TTAGGGAGCATGTGTAACATCAACATCGATGAGTGTGCGGGCAACCCCTGCCACAACGGGGGCACCTGCG AGGACGGCATCAATGGCTTCACCTGCCGCTGCCCCGAGGGCTACCACGACCCCACCTGCCTGTCTGAGGT CAATGAGTGCAACAGCAACCCCTGCGTCCACGGGGCCTGCCGGGACAGCCTCAACGGGTATGCGGCGGGG CCGATCATGGGGACACATCAGTCCTAAACCCTGGGAGCTCTGCTGCCAGGAGGGTGGCACCTGCACAGAG CTTGAGATGGGCCAGAAACGGGCCTCGGACGGGGCTGGGTGGCAGGGAGCTCCCCTCGGGGACGCACATG CCTCTGGGTCCTCAGTCAGACTACAGTCCACACCCAGCAGCTGTGTGCTGCGTGTCCTTGTGGGCTGCAT GGTGTGCTCAGGACACAGGCCCACAGTGACCCTGGAACACGTTTCCATGGTAACAGCCGCAAGTGTTTCT GATGCCCATGATGTGCCTGGCAGCACTCTGCCTGGATGGGACCATTTAAATCAGCAGGGACCCCATTGCC CTCATTTGGCGCAGAGAAGGCACGTGCTTTGTTCGGGGCCACACAGCGGGCAAGTGGTGGGGGGCTTTTC GCAGCACCCTACTGCCCTGCACTTGGCATGGTCCCCTCGCTAATGAACCAAACCCCTGCCGCAGTCTTGG GTATGGGAAGCGCTGCGGCCCCCACTTTTTTCTTTATTTTGAGACAGAGCCTTGCTCTGTTGTCCAGGCT GGAGTGCAATGGCATGATCTCAGCTCACTGCAACCTCCACCCCTCAGGTTCAAGTGATTCCCCTGCCTCA GCCTCCCGAGTAGCTGAGATTACAGGCATGTGCCACCACACCTGGCTAATTTTTGTATTTTTAGTATATA TGGGGTGGGGGAGTTTCGCCATGTTGGCCAGGCTGATCTTGAACTCCTGGCCTCAAGTGACTCAGCCACC CCCGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACAGCGCCCAGCCTGCCCCCACTAAAGGACTCT GCGAGTCTGAGTGGATGGGCACCTCCGCCAGCCCATAGGGCATTGCAGACCCGGGAGTGCCCAGGCCCCG GCCGTGCTGCTCGGGCCTCCCTCGACCTGCAGTGTGGTCCCCCTTGCAGGTACAAGTGCGACTGTGACCC TGGGTGGAGTGGGACCAACTGTGACATCAACAACAATGAGTGTGAATCCAACCCTTGTGTCAACGGCGGC ACCTGCAAAGACATGACCAGTGGCTACGTGTGCACCTGCCGGGAGGGCTTCAGCGGTGAGTGGGCTGCGC GTTTCTCAGTGCAGAGGGCCGCCCTCGAGTCTGGGGAGCTGGAGACACAGGATCGGGACCCAGGTCCAGC CAGCACCATGCATGGTGTCTCCCTCCCGTGGCAAAGCCTTAGCTCCAGGCCTCTGGCTCTTGGAGATGAG GAGGGGCCTGGGGTGGGGAGCAGGCCCAGGGCTGCTGTTGTGGGGCCCTGCCAAGGTGCCTGGGAGTGCT GGACATGCCGAGTGCTGTCCCCTTCCCTCCAGGTCCCAACTGCCAGACCAACATCAACGAGTGTGCGTCC AACCCATGTCTGAACCAGGGCACGTGTATTGACGACGTTGCCGGGTACAAGTGCAACTGCCTGCTGCCCT ACACAGGTGAGGGGTGGGTGGGGCCTGTGCTGGAGGGGGCGGGGCCTATGTGGGAGGGGCGGGACCTGTG CTGGAGAGGGCGGAGCCTGTGCTGGAGAGGGTGGGGCCAGGGGTGGGGGCGGCCTGGGAAGCCGTGACTG GAGGGTAAAGTGGTGGCTTTCTTGGGGCGGGGCCTTCCAGAAGGTTCTGCGCCTCACTGAGTGCCTTAGG CCCCTGCAGTATGTGGGCCTTCTCCCGGGGGTGGGGTTGGCAGATTAGCAAAGATACAGGATGCCTGGGA GAAAATTTTCATGCAAGCATGTGTTTTACCTGGCAAGCCTGCCGCAAGACACAGGTAAGATGCAGGTGAA TCCTTAGCAGGGCCGGGCCTGGGTCACTGGGCTCCGTGCTCCCGGCGCCCACCCTGCTGGGGTCTCTGGG GGCCGGGCTTCCCCACCCCCGCCAGCCGGACCTGAGGGATTCCTTTGATGGCGGGCTCTCTTTGTGTGAG CGGAACAAGGAGCCCTCTGTTTGGGCTGAGCGGGGAGGGGGATGTTCCCCCAACTGTCCAGCCCCTGCTA TGAACCCAGCCAAGGGGATCACAGGAAATGATCTCCTCTAGAAAAGACAAAGAAGAGTCCACAAGCACCG GGGTCCTGGCGCTCCCCAGGAGCGGGCAGAGGGTGCTGCCACGGGGCCTGGTCAGGGAGGGCCTGCCTGG GCCAGGCAGCCGGGCTGGAGGTCCCACGCCTGCGGTTCCCATGACATCCAGCAGCCTGTGGCCAGAACGC TGTTTTCTTTGACCGAAGTTAAGGACCTGGGTTTTCTCTCCTGTGTCAGTCAGTGAGGACCCTCCCTCCA CGGCTGGGCGCCCCTGTCCCTTTCAGACACGTCGATCGGGCCGGCAGGAGGAGCGGCGGTGCTGACCCGC TTCCTATCTGCCCGCTTCCTGCTTCCTTTCGCACAATTGTCGGAAACTCTGGCGCAGTTCCTGCCTGCCC GGGTCACCGTGGAAACCAATAGGAAGAGAGGCCCTGGAAAGTCGCCCCAGCAGGCCAGGGAGATAATGGG GGACAGGGAAGATAACGCAGTCCCCACGGCTATAAACAGGAAGCTCGGCCATGGGCTTGTGCAGAAAAAG GCCCTCGGCTGTGCACGTGGTTCCCACATAGCCTTTGCCAGACACCCTGCGTGGCCCTGGAGGTCTCCAG GCCGTGCCCCGTGCCCCGACACGCAGGATGTGCTGGGGGCCTGGGCCTGTCCCCTCCATCGCAGCCCTTG TTTGTTGGCCTCCCGTGATGGGCGTTTGCTGCCTGTGACACGGAGCCCCAGGATTAGTTTCAGGCCTCGG TCTCAGGCCAGGGCCTTTCCTCGTCACCCAGAGATGAGGGGGCTTGCGTCCGGGGTGGGCCCAGGTCCCT GCAGTGTCGTGGAGCCCACCCGACTGAGGCCGCCTCTCCTGGTGCAGTCCTTGTTCCTGGGCACGCCTGG TGGGGTGAGGCCTAGGCTGTGCCCCGCTGCCAACCGGGAATGAGGGGTGGCTTCTGAGCGTGACATTTGT GCAGCTTGTCTTCAGCGTCCCCCCATCTGTGCTCCACTCCTCCCTGGGTCAGGGTCCTGGCACAGCCGGG AGCGCTCAGGGGTCTCGGTGCACATTTGCCTCCCGGCGGGACCAGCAGACGGCACTCTGATGGCGGAAAG ACCAGCAGGCGGTGGCCGATTTGGGAGATCCCTCTGGGTGAGGCTCCCGGGGTCACGTGTGTCTCCTTCC CGCAGGTGCCACGTGTGAGGTGGTGCTGGCCCCGTGTGCCCCCAGCCCCTGCAGAAACGGCGGGGAGTGC AGGCAATCCGAGGACTATGAGAGCTTCTCCTGTGTCTGCCCCACGGGCTGGCAAGGTGAGGCTGGCCAGG GCCCGGTGAGGGCTGGGATGGGAGGTCAGGATGTCTGCGGGACACAGGCAGCTCCCAGGCAGGCTAGATG AGTCTTTGAAGAGGAGCTGGTGGGTGCTGAGGAGGCCCTGGTCGGAGAAGTTCTGGAATCAGGAATTGAC CTGGGAGCACCGTTCCCAACTCCAGTTCCTGTGACCTTCTTAGGCCAAAATTAGGGGAGAGGGGATGGTC CTGGGGTCACGGAAGCCTACTCCTGGGTCGGGAGAGGCACTGTAGGTGGGTGGGCCAGCCTGGGAAGGGC CTGGAGGGCCAGGGGCCGCTGGTGACCAACCGGCCTCCTCCTGCCCCGCAGGGCAGACCTGTGAGGTCGA CATCAACGAGTGCGTTCTGAGCCCGTGCCGGCACGGCGCATCCTGCCAGAACACCCACGGCGGCTACCGC TGCCACTGCCAGGCCGGCTACAGTGGGCGCAACTGCGAGACCGACATCGACGACTGCCGGCCCAGTGAGT AGCCCCGCGGCTCTGGCCTCCTCCAGGAAGCTCTCAGGCCTCAGTTCCCCCGGGCAGGGTTGGTGCGCAT GGTGCTGGCCATAAGCACCCAGGGAGGCCGGAGTGTGGCCGGGGAGGGTTGGGTCAGGTGTGGGGGATGT GCTGAGGGATGGCCAGGGTGGTTCAGGAGGGCCCCAGAGCCGGCTTGCTCCTCCCTGCACTTCGCGGAAG AGTCACGAGAGCCCCTCCCACGGCTCTTCACTGAGCCGAGGATGGCTCGGGCCCGGCCTGCACTCCCGCC TGGCTCATCGGGCCCCGCTGCAGGCCAGGGCTCTCAGGCCTCCCAGCCCTGCTTCACAGAGGTTGAGGTT GGCAGAAGCCGGGGGTCTTGCTGGCATCACCTGGCAGGCAGAGGCAAGAACTGTCTCTCCTCCCCTGCTC GGTCTGTGAAGCCTGCAAAGCTGCCCCCTGCCCTGGAGCTTGAGGACAGGAGCAGGTGGGGAGAGAGACC CCAAGCACAGGAGACGGGTGTGACGCAGCCTGTGGGTGCTGGGGCTCCCCACCAGACACCTTTGTCACAG GGCTGCTTGCCGCAGCCTCGGCAACGAAAGGCTGGGCTGTCCCCAGCCATGCAGCCTTCCCGGCCCCCTC CCGCAGGTGTGGGTTTGTGCCTGCCCCTCACACTCACCCTTCCGTCCTCTCCCAGACCCGTGTCACAACG GGGGCTCCTGCACAGACGGCATCAACACGGCCTTCTGCGACTGCCTGCCCGGCTTCCGGGGCACTTTCTG TGAGGAGGACATCAACGAGTGTGCCAGTGACCCCTGCCGCAACGGGGCCAACTGCACGGACTGCGTGGAC AGCTACACGTGCACCTGCCCCGCAGGCTTCAGCGGGATCCACTGTGAGAACAACACGCCTGACTGCACAG AGAGGTGTGCGGGGCTCGAGTGAGGCCGTGGAAGGGAACGGGCGGTGCGGGCCACACGCAGTAGCTGGCA GCCTGGCACACCATGCAGGCGTCCGCCTAGGCCGGCTGGGCACTTAGCGCTGGCTGCATTGAGTCCAGAC ATTGTTCATTGTACCGACCTGTCCCTCCTGAGAGGGCCATTGTGACCTCCTCCTGTGTCCCGCACCAGGA GCGCCGGTAGTCTGTCCTGAAGAACTGGTGCGCTTCCTTCTATTAGACAACGAGAACTCTGTCCGTTCTT GTTTCCTTTTTGCCGTGTTTGCCAGGAAGCTCATTTGGTAAACGTCAGTCTCGTCCCTGGTTTCTGACGT AATTACCTCCCGTGTTACCAGGACGGTTTCTGGTTTCTCCCTCATTTACTTTAACCACCCTATGCCCACG CGTTTGGTAAAACCACTCTCGACCTGACTTATAAAGAAAGCAGGGGAGGGAGGTGTGACGTGGTGTGAGA GCCGGGCCCCGGGTTCCCACTGGCCTCCCTGGGTCAGCCAGGCTGCCCTGGGCCTGTCCTGGCCATCAGG CCCCTAGGGTTGAGCAGAAGGGGAGGTGCTGGCGAGGCAGAATCTGCTGGAGCGGGGACCCACCAATGCC CTCCACTCAGCCCCCGCCTGCCCACCCCCTTGCAGCTCCTGCTTCAACGGTGGCACCTGCGTGGACGGCA TCAACTCGTTCACCTGCCTGTGTCCACCCGGCTTCACGGGCAGCTACTGCCAGCACGATGTCAATGAGTG CGACTCACAGCCCTGCCTGCATGGCGGCACCTGTCAGGACGGCTGCGGCTCCTACAGGTGCACCTGCCCC CAGGGCTACACTGGCCCCAACTGCCAGGTGAGTGCGCCGGCCACAGAGGTGCCCGAAGGAGGGGCCCTGG GTGGGTGCCTACCTGCGGGAGGTGGGAACGGTCACCCCAGGTCCCACTGTGTCGGCTCGGGGTCACCCCC ACACCCCCGGGCAGAGGGTTTCTGGGGATCTGAGCAGCCGGTGAAGGAACCTGATGCGGAAGCAGCAGGC ACCTTCGTTTCAATCCCAGGTTTCTGGAGCCGGGGCAGGAGCTCAGGAATTGGGGAATTGAGGAAAAGTG TTCCTTCTAGCAAAGGCCGAGGGTGGTCTGGACCTGCTGAGGGCCCTGAGGGAGACCCAGCCCAGGCTGT TCCTGGTGTGGGGGTGGTGGGGAGTCCAGGGGCGGCAGTTTCCACTTCTGTAGAATGGGTTGCAGCCTGG GTTGGAGTAGGCCCCTTGGCAGATGTGCGTTCTGAGCTACCGGGGAAATGGCCGGGGCGCGGGCACCCAG CTGACCCCAATCTGTCCCCAGAACCTTGTGCACTGGTGTGACTCCTCGCCCTGCAAGAACGGCGGCAAAT GCTGGCAGACCCACACCCAGTACCGCTGCGAGTGCCCCAGCGGCTGGACCGGCCTTTACTGCGACGTGCC CAGCGTGTCCTGTGAGGTGGCTGCGCAGCGACAAGGTAACCTGCTGTGCCCACCCAGCTCGGGTCCCAGC CCATCAAGGTCCTCTGTGGGCCTGGGCCTCACCTGTCTACCACCCCATCCCCCGCAGGTGTTGACGTTGC CCGCCTGTGCCAGCATGGAGGGCTCTGTGTGGACGCGGGCAACACGCACCACTGCCGCTGCCAGGCGGGC TACACAGGCAGCTACTGTGAGGACCTGGTGGACGAGTGCTCACCCAGCCCCTGCCAGAACGGGGCCACCT GCACGGACTACCTGGGCGGCTACTCCTGCAAGGTGGGGGTCCCTCCTAGGGTAAGGGTTGTGGCCGGCAC GAGTGTTGCCACACACCAGGCCCTGGCTGGGAGCTGGCCCAGTGGAGAAAACTGAACCTGATAGGCCCAT GCACTGTTCAGTCTCATTAGGGGAGGGCTGGGGTAATCAGGGTAGACTGCCTGGAAGAGGTGGCCTGTGG AAAGCCTGAAGGAGGGTACCTATACTGAGAAGTGGGATGGGGTTTTCCCTTCCCCTAGATTGTGTCTGGG CTTGGCCAACACCTACCCTGAGGCCCTCACCTCTATCCTATGGGACGGGGTCCACCCACCCCCAACAGGC AGTGACTCCGGTCACCGAGGCCCCGCCAGGGTCTGTTGGGCTGGGTCTCTCTCCAGGTCTGACAGGAGCG AGGGGCCCGTGGCTTCGCTGGACCTGAGGGCAGCTCATGTGGCCCTGTCAGCCCTCACAGTGGGGTGTGG GAGCACTGCATCCTGGCGCCGGCTGAGCCGAAGGGCCCCTCGTTCTGTCGCCTGCACAGTGCGTGGCCGG CTACCACGGGGTGAACTGCTCTGAGGAGATCGACGAGTGCCTCTCCCACCCCTGCCAGAACGGGGGCACC TGCCTCGACCTCCCCAACACCTACAAGTGCTCCTGCCCACGGGGCACTCAGGGTAAGGGCCGCTGCACGG AGGGCTGGTGTTGGCCATCCATGGCCAGGGCAGGGGCAGGGCAGGCACCCCGGGACCGGCCAGAGGCATC CAGGAACCAGCCAGAAACTCCCATTTTCCTGTGTGAGGCCAAGGCCGACTCACAGCTGCCCAGGGAAAGG GCCCAGAGCGGGGGTCCCAGTGGGAAGGGCGTCTCCACGGCACCCTTGACACCTGCCTCTCCCGAGTGTC CGTGCAGCCCCAGACCTGAGCGCTCGTCTTCCGGGACGGACACGCGGCACGGCAGGGCCGGGGTGTGGCG GGCTTGGGCCACTGACGAAACCTGGCCCCGCAGGTGTGCACTGTGAGATCAACGTGGACGACTGCAATCC CCCCGTTGACCCCGTGTCCCGGAGCCCCAAGTGCTTTAACAACGGCACCTGCGTGGACCAGGTGGGCGGC TACAGCTGCACCTGCCCGCCGGGCTTCGTGGGTGAGCGCTGTGAGGGGGATGTCAACGAGTGCCTGTCCA ATCCCTGCGACGCCCGTGGCACCCAGAACTGCGTGCAGCGCGTCAATGACTTCCACTGCGAGTGCCGTGC TGGTCACACCGGTGGGTGCCGCGCCCAGGCGGGTGGGGCGTGTGGGGCAGCAGGGTGAGCCTCTCACTGC CCTGCTCTTACCCCTAGGGCGCCGCTGCGAGTCCGTCATCAATGGCTGCAAAGGCAAGCCCTGCAAGAAT GGGGGCACCTGCGCCGTGGCCTCCAACACCGCCCGCGGGTTCATCTGCAAGTGCCCTGCGGTAGGTGCAG GGGTGCAGGGAGGCAGGGGCCCGCCAGGGGAGACACCTGGAGAGGTCCACGTGGGGGCCTCGGGGCGCAG ACCGGGCAGTGATCCTCCCGGCCTTCATCCTCCTCCTCACCCTGATGTCTTTTTTTTTTTTTTAGTTTCA ATAAATGATTTTAGAGACATTTTAGATTTATAGAAAAATGGAGCAGGAAGTAGACTCCCTGGGGTGGCTG TCCCCTGCACGCAGTTCCCCTGGTTAGCAGCTTGCATCAATTTCACTCTGGATTTCAGTGATACATTGTT ACCAACAGCAGCCCTTCCTGTACCTGGGGCTTGCCCTTGGCTTTGTGGTTGTGGGTTTGGGCTGAGGTAT GACATGCCTGCCCACCCTCGCAGGATCACGGCAGAGAGTCCCTGCCCTAAAGTCCTCAGCACTCCACCAG TTTACCCCTTCCTCCATCTCCCGACCCCCTGGCACCCCCGATCTTTCTCTGTTGGTAGAATGTGTGTAAA GGGTTTTGCTGCTGGGGGCAAGGTTGCAGGCCGCCTCCCAGGTTAGAGGAGAGCGGTGGCACTGCTGGCC GAGGGCTGGGTGTGAGGTGGCGGGGGGGCGGGGGGTGGCCCACCCCGACACCGTCCTGTCTTCCCTCTCG GGCAGGGCTTCGAGGGCGCCACGTGTGAGAATGACGCTCGTACCTGCGGCAGCCTGCGCTGCCTCAACGG CGGCACATGCATCTCCGGCCCGCGCAGCCCCACCTGCCTGTGCCTGGGCCCCTTCACGGGCCCCGAATGC CAGTTCCCGGCCAGCAGCCCCTGCCTGGGCGGCAACCCCTGCTACAACCAGGGGACCTGTGAGCCCACAT CCGAGAGCCCCTTCTACCGTTGCCTGTGCCCCGCCAAATTCAACGGGCTCTTGTGCCACATCCTGGACTA CAGCTTCGGGGGTGGGGCCGGGCGCGACATCCCCCCGCCGCTGATCGAGGAGGCGTGCGAGCTGCCCGAG TGCCAGGAGGACGCGGGCAACAAGGTCTGCAGCCTGCAGTGCAACAACCACGCGTGCGGCTGGGACGGCG GTGACTGCTCCCTCAACTTCAATGACCCCTGGAAGAACTGCACGCAGTCTCTGCAGTGCTGGAAGTACTT CAGTGACGGCCACTGTGACAGCCAGTGCAACTCAGCCGGCTGCCTCTTCGACGGCTTTGACTGCCAGCGT GCGGAAGGCCAGTGCAAGTAAGGCTGCGGGGCTCATGGGGCTGAGGGAGGACCTGAACTTGGATGTGGCC TGGCTTGGGCCCGGAGGCCAGCATGCAGTTCTAAGGCTCTGCTCAGGGGGTGCAGGGACGTCCCCCGCGG CTGGCCAGTGGGCTGGAGGCACCGGACGGCGGGTGCGAGGCCCCCCGAGGAAGGCGGCCTGAGCGTGTCC CGCCCCCCACAGCCCCCTGTACGACCAGTACTGCAAGGACCACTTCAGCGACGGGCACTGCGACCAGGGC TGCAACAGCGCGGAGTGCGAGTGGGACGGGCTGGACTGTGCGGAGCATGTACCCGAGAGGCTGGCGGCCG GCACGCTGGTGGTGGTGGTGCTGATGCCGCCGGAGCAGCTGCGCAACAGCTCCTTCCACTTCCTGCGGGA GCTCAGCCGCGTGCTGCACACCAACGTGGTCTTCAAGCGTGACGCACACGGCCAGCAGATGATCTTCCCC TACTACGGCCGCGAGGAGGAGCTGCGCAAGCACCCCATCAAGCGTGCCGCCGAGGGCTGGGCCGCACCTG ACGCCCTGCTGGGCCAGGTGAAGGCCTCGCTGCTCCCTGGTGGCAGCGAGGGTGGGCGGCGGCGGAGGGA GCTGGACCCCATGGACGTCCGCGGGTGAGTGAGACCCGGCGCCCACGGTCAATCCCCGCAACTCTCCTGG GCCCTCCCCGACGGCCTCCCTGCCCCTCACGGCCGGCGCCATGGCAAGCAGTACTCTCCCCACTTTATGG TAAAAGAGACGGAGGTTCCGAGAGGACCTGGGACTTCAGGGCCTGCGCAGGCAAGGAGTAGAGGCAGCAT TCCAGCTCAGGGCCCTGACCCCACAGCCACACCCTTTTCCTGGGCCACTGCCTTCCCCTGGACAGGCGGC ACTCCTGTGCCCAGTAGGTGATTTTGAGATTGAGCTGTGCCTTAGGCACTGGATACTACACTGATTAAAA CTCAGCCCTCTGCCAGGCGAGGAGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCTGAGGCAGGCGGA GCCCTTGAGCCCAGGAGTTCGAGACCAGTCTGGGCAACATAGGGAGACCTTGTCTCTGTTTTTTTTAAAA AAGTATTAAAAGAAGTAAAAAACAAAACACTCAGCTCTCCAGGGGTTCCCACAGGGCTGAACAGCCCCAC CCCAGACAAGAATGCCGCTTGGTCATGGCGTCTGCCTGGCTTGGGCTGGAGAGGAGGCAGGTGGAGGTCC TGGGAGGGGGCATTGCTGGGCCTTGCAGTTGGAGGAGGAGCTGGTGGGGGTGGGGGGTCCCACGGTGGGA GAACACAGGCAGGAGCAGCTTGAGTGCAGGGGGCACCCCACAAGGCTCCCGCCCATGCCTACTCGATCTG GGGCAGCTGGACCCAGGAGCCAGGTTGGTTGTGCCCTTCGTGTGCCTGACCCTGGTGGGTTTGCCTGTCA GTTCTGCTGGCTTGGAGCAATCCTGGAGGTCAGAAGCATCATCTCACAGGCTGGATGGGATCCTGCTCAC GGGAACCCAGTCCTGGGGAGCAGAGCTCACCCCCAGCCAGCCTCACCACACAGCCCACCACCGCTGCACC CACCCCCACCTCACGCCTGTGCTTCCTGCAGGGCCTGGGGATGGCTCCTGGGGGAGGACTGGGCTCCTGG CACATACTCTGTCCTGAGATGAGGAAACGTGTCTGTGGCACCAGCAGGAGCCAGAGAGGGTGTCAGGGCG GGCCAGGGAGAGCGCGTTGGTGGGTATCTGGGATGAGCCGTGATCAGCACTGGCCGGAGTCGGGGGGCTG GCACCAGTCCCCTGCAGGGTAGCTGCTGTCAGACCTGGCTTCCCACCACCCCAGGCTGCCTCACCATGTC CTGACTGTGGCGTCATGGGCCTCAGTGTCCTGCGGCAGCATCCCTGGCCGGTGGGCGGGGGAGGAGGAAG CCTCGGGTCCCAGCCCCTCTCTGATTGTCCGCCCAGCTCCATCGTCTACCTGGAGATTGACAACCGGCAG TGTGTGCAGGCCTCCTCGCAGTGCTTCCAGAGTGCCACCGACGTGGCCGCATTCCTGGGAGCGCTCGCCT CGCTGGGCAGCCTCAACATCCCCTACAAGATCGAGGCCGTGCAGAGTAAGTGTGGCCCCATCCCGGGAAC AGGCTCTGCCTGCAGGGGGTGCCATCCCCCCGTGCCCCAGACACGCTGGCTGTTTGTGCCAGTTGCTACC CACGGGTGTGAGCGTTGCCGTCCGAGTTGGGGTAGGGCTTTTCTGGAATTTTCTGAATGGCACTCCGCCC CCACCTGCGGCGGTCACAGCTGCCGGTGGAGCCACCTGGGAACGAGTCCAGCCACGGGAAAGTGGGTGCC TGCTTCTCTCCCCACCCTTTCCTCCTGAATTTTCTTTGTTGGGTATTATTTCAAAATCATTACGGCTTTT TTTAAAGAAAAAAAAAGAGAGAGAGAGAAGAATTGATCGGTGTCATGTGAAGTGTTGAAGTTTGTATCTT GAAAATCCCTCTAAATCCTTTGTCTTAACAGCTCAGTGCGAGTGCAGCGATTTGAAGTTGACTAATCCTC CTTCCTTAAAGGAGAAAAAAGTAAAAGCCGTCTCCAGATAGAGTCGGCTGGTGCAGGAGAGAATTTAGCG ATAGTTTGCAATTCTGATTAATCGCGTAGAAAATGACCTTATTTTGGAGGGCGGGATGGAGGAGAGTGGG TGAGGAGGCGCCCGGACGCGGAGCCAGTCCGCCGCCCCCCGGCCACCAGCCTGCTGCGTAGCCGCTGCCT GATGTCCGGGCACCTGCCCCTGGCCCCCGTGCCCGCAGGTGAGACCGTGGAGCCGCCCCCGCCGGCGCAG CTGCACTTCATGTACGTGGCGGCGGCCGCCTTTGTGCTTCTGTTCTTCGTGGGCTGCGGGGTGCTGCTGT CCCGCAAGCGCCGGCGGCAGCATGGCCAGCTCTGGTTCCCTGAGGGCTTCAAAGTGTCTGAGGCCAGCAA GAAGAAGCGGCGGGAGCCCCTCGGCGAGGACTCCGTGGGCCTCAAGTGAGCGGACGCCGCCCCTGCTTCT GGGTCCCCGGTGGGAGGTGGGACCTGGCCGAGCATCCTCACCGGGAGTCTGCCCCTCCCGACCCAGGGCC CACCTCCCACGCCAGGCCCGGGCCAGGGGTCTCTGGGGGCTTCCTAGGGAGCTCGCTCAGCCTCACTTCT CGACCCCTCACCCCCCAGGCCCCTGAAGAACGCTTCAGACGGTGCCCTCATGGACGACAACCAGAATGAG TGGGGGGACGAGGACCTGGAGACCAAGAAGTTCCGGGTGAGTCGCGAGGCTCCCGGGCTCCTGGGCTCCC GGGCACCTGCTGCCGGGCTGCCCTGACAGGCTCTGCTCACTCCCTCTATGTAGTTCGAGGAGCCCGTGGT TCTGCCTGACCTGGACGACCAGACAGACCACCGGCAGTGGACTCAGCAGCACCTGGATGCCGCTGACCTG CGCATGTCTGCCATGGCCCCCACACCGCCCCAGGGTGAGGTTGACGCCGACTGCATGGACGTCAATGTCC GCGGGCCTGGTAAGGGTGCCAGCAGCCAGGGCTTCCCTAGCCCCGTGGCCCACCTGCCTCTCTCCCCTAA GCCCCGAGGCTGGGGTACAGTTGATACTCTGGAAACTTAGAATTGGGGGTGAGAGCTTTCATCCTTGGGG TGTTTCCCATTCAGAGTAGACGTGGGGGGGTCCTGGAGTCCTCCTGTTCTTCCACCAACCCCTTCCTGGG GTGATACCGCAGGGCCACTCTGTCCCTGTAAATTACTCTTTTCTGAAACCTTCTTGAGACATGGAAAGCG TTGATTTTCTTTTTCTTTTTTTTTTTCTTTTTTTTTTGTTTTTGAGATGGAGTCTCGCTCCGTCACCCAG GCTGGAGTGCAGTGGCACGATCTCGGCTCCCTGCAACCTCCACCTCTCGGGTTCAAGCAATTCTCCTGCC TCAGCCTCCCCAGTAGCTGGGACTACAGGCGCCTGCCACCACACCTGGCTAATTTTTGTATTTTTAGCAG CGATGGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACTCCTGACCTCAGGTGATCCGCCCACCTCGGC CTCCCCCAGTGCTAGGATGACAGCGTGAGCCTCCGCATCCTGCTGAAGCATTAATTTTCTAACTGCATGC TTCTGGGGTCCTCTTTTTCCTGGGTGGATTTTGGGTGCCAGGTCTTGGGCAGGTCAGGAAGCAGTTGCCC GCCAGGAGTTTAAGCTGGATTCGGCTCTGTCCACTGAGCAGCCCAGGCGGACTTCAGCTGCCCCTTGGTG GCTGTGTGCACGGGGCCACCAAGTGCTGGGTGGTGCATCCACACCGTGGCCCCTTGAGCTTGGGGCTGCT GCCCCCCTCCCCCTGGGCTGCAGCTGGGGACCGGCCCTCCAGACTGAGCACCCGTCTCTGCCTCTGCAGA TGGCTTCACCCCGCTCATGATCGCCTCCTGCAGCGGGGGCGGCCTGGAGACGGGCAACAGCGAGGAAGAG GAGGACGCGCCGGCCGTCATCTCCGACTTCATCTACCAGGGCGCCAGCCTGCACAACCAGACAGACCGCA CGGGCGAGACCGCCTTGCACCTGGCCGCCCGCTACTCACGCTCTGATGCCGCCAAGCGCCTGCTGGAGGC CAGCGCAGATGCCAACATCCAGGACAACATGGGCCGCACCCCGCTGCATGCGGCTGTGTCTGCCGACGCA CAAGGTGTCTTCCAGGTAGGCAGTGGCTGCCTGTGTGCCCACCTGCCCTCCTCAGGGCCGCCTGGTGGTC TGGGGCAGTGGCCAGGCTTACGTGGCCCTGGGAGCCTGACCCCGAGCACAGCTGAGTCCGGGACAACTGG TGCCTCCACCTGGGACCTTCGCAGTCAGCGAGGTGCGAGGGGGAGGGCGTCGGGCCCATCTGTGTTCTCC AGGGAAGTCAGGCAGAGGCGGGTCTGGCAGGAGGCCTGGGGGATCTGCTGAGTGAGGCAGCACCTCCCCA CCCCCAGCAAAACAGGCTCCATCAGGGTTGTGGGCCTTGCTCAAGGTCCAGGTTCCACTGCTGCAGCCCC TCGCAGCCCCGCCCCTCCCTCAACCTTGGCTGCCGGCGTAGCCTGTGGCAGTGAGAAGCAGGGTTTAGAG GCTGCCGCTCGGTGCCTGCAGACCTAGGGCTCAGCTTGCCGGTGAGCTCGTGGCAAGAATGGATTTAGGG ATTTGGATGCCTGGGTCTCCAGGGAGTGTCCCTGGCAGGGGCTGCCTTTGCAGTCACCCCTGCTGCGAGT CCCCAGGCTCCAGGCGGCCCTGGAGCAAGCAGGTTCAGATGGGCACAGCCCGGGGAGTTACCACAGAGCT TCTCATTTCCTGATTTCTTAGCTCAGGTGACACATTGTCATCTCGCAGAAATAAATGTAGGTGAGCAGAA AGAGCGTGGAAGGGAGCCCCGTGCGGGTTTGGTGTGTGCCTCTCTCAGCTGCCTTCTTTGCACAGATGTG GAAGTTCCCAGGTGCTTTGCAGGAATCAGGCCAAGTTGCCTTTTGCACCCGCCAGTGAGCAGGGGCCATT CCTCCTGCCAGATGCCAAGACCCGGCTGCATTACAAGGGCTGCCCACCCCCTCTCTGGGCAGAGCCGGAC ACTAGCTCGGCGGTTCTGAGACGGCTGTAGGGCCGTGAGCCCGGCTTCCTGAGTGCCAGCTGTAACCGCC GTTGGGGGCAGGGACTTGACCTCTCTGTTTTGTAGGTGGTCATGGCAGCTAGGACCACAGTGAGGATTAA ATGAGGCCACACGTGGTCACGATGGATCCCACTGTCACCAAGGGGCCTGTCTGTGGGCAGCACAGCCCCT GCCCCCATCCGGGCCCCTCCTCAGGGGCAGCCCCATGGCGTTTCGTCTTGCCCGGCCGTGCCGATCTCAG GAGGGTCTCGTCTGTGTCCGGAAGACAGTGGGGCTTCCCGTCCAGGCGTTCGTTCTGGGCAGGAGGCATC GGTGTACGTCTGCCCAGCACCCGCCTGAGCCTCTCCCTGTTGCCCAGATCCTGATCCGGAACCGAGCCAC AGACCTGGATGCCCGCATGCATGATGGCACGACGCCACTGATCCTGGCTGCCCGCCTGGCCGTGGAGGGC ATGCTGGAGGACCTCATCAACTCACACGCCGACGTCAACGCCGTAGATGACCTGGGTGAGCCCACGGGGG CACGGCTGCTCTGTCGTGGGGCGGGACCGCCACAGGGACGGGTGGGACTGGGTTGCCTCCAGCTGGTCTC CAACCTACCCCATCTGCTTCTTTCACGCAGGCAAGTCCGCCCTGCACTGGGCCGCCGCCGTGAACAATGT GGATGCCGCAGTTGTGCTCCTGAAGAACGGGGCTAACAAAGATATGCAGAACAACAGGGTGAGCGCGAGG CTGGGATGCCAGGGGAGACGTGAGGGCTGAATCCACAGAGAAGTGAGGGCCAAACCCACGGGGCGCAGGG ACACAAGGGCCTGACCCACAGGGTCTCGAGGGTCGCTGGGCCCGCATGTGGGCCCCACCCGCATGATGCG GGCACCTCGTTAGTGCTCCTGCCTTCCTTCAGCCCCCGTTTATGGAGCCCTTCCAAGTGCAGGTCCAGCT GTCAGGACACGGCGGCTCGCCCCTCAGACCCAGCCCTACCCTCCTGGGCGGCAGTCATGGCGGGGCACAC AGCCTGGCGTGGGGAACGCTGCTGCTGCCACTGCTGTGTCACCGTCACCTGGACCTCACCTTCTGTCCCC AGCTGTCACCAGGCGGGGGTGGGGATGGGAATGTGGTGACGCAGGTGGTGCAGATTGAGCCAGAACACGC GTGGCGGCAGCTCCCTGCGGGGCGGGGCCTCTTGGTGTGTTCACCAAGGCCAAGGACCTCAAGGCTCAGA GGAAGAAGTCTCAGGACTATATCCAAGGGGAGCCACCCCCAGCCCTCATCCTGGCCCTGCAGCTCCTGGC CCTGCAGCTGCTGTTGGTTTCCCCTGGGTGCTCAGGGCACAGGTGCAGACACCCCCACCTCCCTGCCGCC AGAACCCCCACCCCCGCCCCCAACTCCTGCTGCCCCCTTGGCATGTCAGGCTCAGGCGTCTCTCCCTCCT GGGTGAGGGCACACAGCGGGCCTGGGCACCGGGGCATGTTGGCCCAGGCGCTCCCCAGTCCGTGGCAGCA TGGCCCCACAGAGACTGGGCCCCAGAGGGCATCAAGGCCTGGGAAGCCCCTTCCCACTCCCACACAGCAG CCTCACCCAGACCTGTGACGTGTCCACCGCACAGAGGAGACCCCAGGAAGGAGCTTGGTGGCCACCAGGG TGGCTTGATGGCCGTCCAGATGACGAGCTCCCTCCCTGGTGCCCTCGCCGGTGCCTCTGAACCGCTCCAG GAATTTCCTTTTGTGCCTTATTGGGGGCAGGGAAGAGGGCCTGCAGTTGGTTAGATTTTCAGTGGGGTCT GTGACCCCCCCATAGAGGTGGAGCCCCGCTGATCTAGGGTAGAGGACTGCACAGATCCCCTCTCTGGGTG GGTTTCAGAAGATGTATCAAAGCCTTAACATTTAACAAGAGTCAGGCTAGGTGGTTGCAGGACGCTGGGG TGGGGTCCTGAGGAGCAGCCTGCCTGCCCCCACCCCGCGGAGGAGGTTGTACTGCTGCTTCCTCTGGTGA TGGAACCTTGGGGAGGGTCCCCACGCCTGGCCTGGCCCCCCTCACCGGCCCCCGCCCTCATCCCCCAGGA GGAGACACCCCTGTTTCTGGCCGCCCGGGAGGGCAGCTACGAGACCGCCAAGGTGCTGCTGGACCACTTT GCCAACCGGGACATCACGGATCATATGGACCGCCTGCCGCGCGACATCGCACAGGAGCGCATGCATCACG ACATCGTGAGGCTGCTGGACGAGTACAACCTGGTGCGCAGCCCGCAGCTGCACGGAGCCCCGCTGGGGGG CACGCCCACCCTGTCGCCCCCGCTCTGCTCGCCCAACGGCTACCTGGGCAGCCTCAAGCCCGGCGTGCAG GGCAAGAAGGTCCGCAAGCCCAGCAGCAAAGGCCTGGCCTGTGGAAGCAAGGAGGCCAAGGACCTCAAGG CACGGAGGAAGAAGTCCCAGGACGGCAAGGGCTGCCTGCTGGACAGCTCCGGCATGCTCTCGCCCGTGGA CTCCCTGGAGTCACCCCATGGCTACCTGTCAGACGTGGCCTCGCCGCCACTGCTGCCCTCCCCGTTCCAG CAGTCTCCGTCCGTGCCCCTCAACCACCTGCCTGGGATGCCCGACACCCACCTGGGCATCGGGCACCTGA ACGTGGCGGCCAAGCCCGAGATGGCGGCGCTGGGTGGGGGCGGCCGGCTGGCCTTTGAGACTGGCCCACC TCGTCTCTCCCACCTGCCTGTGGCCTCTGGCACCAGCACCGTCCTGGGCTCCAGCAGCGGAGGGGCCCTG AATTTCACTGTGGGCGGGTCCACCAGTTTGAATGGTCAATGCGAGTGGCTGTCCCGGCTGCAGAGCGGCA TGGTGCCGAACCAATACAACCCTCTGCGGGGGAGTGTGGCACCAGGCCCCCTGAGCACACAGGCCCCCTC CCTGCAGCATGGCATGGTAGGCCCGCTGCACAGTAGCCTTGCTGCCAGCGCCCTGTCCCAGATGATGAGC TACCAGGGCCTGCCCAGCACCCGGCTGGCCACCCAGCCTCACCTGGTGCAGACCCAGCAGGTGCAGCCAC AAAACTTACAGATGCAGCAGCAGAACCTGCAGCCAGCAAACATCCAGCAGCAGCAAAGCCTGCAGCCGCC ACCACCACCACCACAGCCGCACCTTGGCGTGAGCTCAGCAGCCAGCGGCCACCTGGGCCGGAGCTTCCTG AGTGGAGAGCCGAGCCAGGCAGACGTGCAGCCACTGGGCCCCAGCAGCCTGGCGGTGCACACTATTCTGC CCCAGGAGAGCCCCGCCCTGCCCACGTCGCTGCCATCCTCGCTGGTCCCACCCGTGACCGCAGCCCAGTT CCTGACGCCCCCCTCGCAGCACAGCTACTCCTCGCCTGTGGACAACACCCCCAGCCACCAGCTACAGGTG CCTGAGCACCCCTTCCTCACCCCGTCCCCTGAGTCCCCTGACCAGTGGTCCAGCTCGTCCCCGCATTCCA ACGTCTCCGACTGGTCCGAGGGCGTCTCCAGCCCTCCCACCAGCATGCAGTCCCAGATCGCCCGCATTCC GGAGGCCTTCAAGTAAACGGCGCGCCCCACGAGACCCCGGCTTCCTTTCCCAAGCCTTCGGGCGTCTGTG TGCGCTCTGTGGATGCCAGGGCCGACCAGAGGAGCCTTTTTAAAACACATGTTTTTATACAAAATAAGAA CGAGGATTTTAATTTTTTTTAGTATTTATTTATGTACTTTTATTTTACACAGAAACACTGCCTTTTTATT TATATGTACTGTTTTATCTGGCCCCAGGTAGAAACTTTTATCTATTCTGAGAAAACAAGCAAGTTCTGAG AGCCAGGGTTTTCCTACGTAGGATGAAAAGATTCTTCTGTGTTTATAAAATATAAACAAAGATTCATGAT TTATAAATGCCATTTATTTATTGATTCCTTTTTTCAAAATCCAAAAAGAAATGATGTTGGAGAAGGGAAG TTGAACGAGCATAGTCCAAAAAGCTCCTGGGGCGTCCAGGCCGCGCCCTTTCCCCGACGCCCACCCAACC CCAAGCCAGCCCGGCCGCTCCACCAGCATCACCTGCCTGTTAGGAGAAGCTGCATCCAGAGGCAAACGGA GGCAAAGCTGGCTCACCTTCCGCACGCGGATTAATTTGCATCTGAAATAGGAAACAAGTGAAAGCATATG GGTTAGATGTTGCCATGTGTTTTAGATGGTTTCTTGCAAGCATGCTTGTGAAAATGTGTTCTCGGAGTGT GTATGCCAAGAGTGCACCCATGGTACCAATCATGAATCTTTGTTTCAGGTTCAGTATTATGTAGTTGTTC GTTGGTTATACAAGTTCTTGGTCCCTCCAGAACCACCCCGGCCCCCTGCCCGTTCTTGAAATGTAGGCAT CATGCATGTCAAACATGAGATGTGTGGACTGTGGCACTTGCCTGGGTCACACACGGAGGCATCCTACCCT TTTCTGGGGAAAGACACTGCCTGGGCTGACCCCGGTGGCGGCCCCAGCACCTCAGCCTGCACAGTGTCCC CCAGGTTCCGAAGAAGATGCTCCAGCAACACAGCCTGGGCCCCAGCTCGCGGGACCCGACCCCCCGTGGG CTCCCGTGTTTTGTAGGAGACTTGCCAGAGCCGGGCACATTGAGCTGTGCAACGCCGTGGGCTGCGTCCT TTGGTCCTGTCCCCGCAGCCCTGGCAGGGGGCATGCGGTCGGGCAGGGGCTGGAGGGAGGCGGGGGCTGC CCTTGGGCCACCCCTCCTAGTTTGGGAGGAGCAGATTTTTGCAATACCAAGTATAGCCTATGGCAGAAAA AATGTCTGTAAATATGTTTTTAAAGGTGGATTTTGTTTAAAAAATCTTAATGAATGAGTCTGTTGTGTGT CATGCCAGTGAGGGACGTCAGACTTGGCTCAGCTCGGGGAGCCTTAGCCGCCCATGCACTGGGGACGCTC CGCTGCCGTGCCGCCTGCACTCCTCAGGGCAGCCTCCCCCGGCTCTACGGGGGCCGCGTGGTGCCATCCC CAGGGGGCATGACCAGATGCGTCCCAAGATGTTGATTTTTACTGTGTTTTATAAAATAGAGTGTAGTTTA CAGAAAAAGACTTTAAAAGTGATCTACATGAGGAACTGTAGATGATGTATTTTTTTCATCTTTTTTGTTA ACTGATTTGCAATAAAAATGATACTGATGGTGA Download Select all
Length	51343
OMIM ID	190198
HGNC ID	HGNC:7881
Unigene ID	Hs.495473
Ensembl ID	ENSG00000148400
PharmGKB ID	-

mRNA Information

mRNA ID	NM_017617.3
Exon	join(1..61,1685..1763,21808..22070,22599..22937, 26222..26344,26963..27196,27495..27650,27850..28035, 28402..28515,29693..29806,30071..30304,30387..30497, 31085..31277,32250..32395,32653..32766,34516..34635, 34982..35134,35826..36054,36716..36917,37402..37555, 37648..37832,38350..38482,38814..39071,39148..39260, 39906..40477,40683..41114,42457..42605,43299..43515, 43699..43786,43874..44039,44940..45235,46528..46675, 46791..46888,48229..51343)
mRNA Sequence	>4851 ATGCCGCCGCTCCTGGCGCCCCTGCTCTGCCTGGCGCTGCTGCCCGCGCTCGCCGCACGAGGCC CGCGATGCTCCCAGCCCGGTGAGACCTGCCTGAATGGCGGGAAGTGTGAAGCGGCCAATGGCAC GGAGGCCTGCGTCTGTGGCGGGGCCTTCGTGGGCCCGCGATGCCAGGACCCCAACCCGTGCCTC AGCACCCCCTGCAAGAACGCCGGGACATGCCACGTGGTGGACCGCAGAGGCGTGGCAGACTATG CCTGCAGCTGTGCCCTGGGCTTCTCTGGGCCCCTCTGCCTGACACCCCTGGACAATGCCTGCCT CACCAACCCCTGCCGCAACGGGGGCACCTGCGACCTGCTCACGCTGACGGAGTACAAGTGCCGC TGCCCGCCCGGCTGGTCAGGGAAATCGTGCCAGCAGGCTGACCCGTGCGCCTCCAACCCCTGCG CCAACGGTGGCCAGTGCCTGCCCTTCGAGGCCTCCTACATCTGCCACTGCCCACCCAGCTTCCA TGGCCCCACCTGCCGGCAGGATGTCAACGAGTGTGGCCAGAAGCCCGGGCTTTGCCGCCACGGA GGCACCTGCCACAACGAGGTCGGCTCCTACCGCTGCGTCTGCCGCGCCACCCACACTGGCCCCA ACTGCGAGCGGCCCTACGTGCCCTGCAGCCCCTCGCCCTGCCAGAACGGGGGCACCTGCCGCCC CACGGGCGACGTCACCCACGAGTGTGCCTGCCTGCCAGGCTTCACCGGCCAGAACTGTGAGGAA AATATCGACGATTGTCCAGGAAACAACTGCAAGAACGGGGGTGCCTGTGTGGACGGCGTGAACA CCTACAACTGCCGCTGCCCGCCAGAGTGGACAGGTCAGTACTGTACCGAGGATGTGGACGAGTG CCAGCTGATGCCAAATGCCTGCCAGAACGGCGGGACCTGCCACAACACCCACGGTGGCTACAAC TGCGTGTGTGTCAACGGCTGGACTGGTGAGGACTGCAGCGAGAACATTGATGACTGTGCCAGCG CCGCCTGCTTCCACGGCGCCACCTGCCATGACCGTGTGGCCTCCTTCTACTGCGAGTGTCCCCA TGGCCGCACAGGTCTGCTGTGCCACCTCAACGACGCATGCATCAGCAACCCCTGTAACGAGGGC TCCAACTGCGACACCAACCCTGTCAATGGCAAGGCCATCTGCACCTGCCCCTCGGGGTACACGG GCCCGGCCTGCAGCCAGGACGTGGATGAGTGCTCGCTGGGTGCCAACCCCTGCGAGCATGCGGG CAAGTGCATCAACACGCTGGGCTCCTTCGAGTGCCAGTGTCTGCAGGGCTACACGGGCCCCCGA TGCGAGATCGACGTCAACGAGTGCGTCTCGAACCCGTGCCAGAACGACGCCACCTGCCTGGACC AGATTGGGGAGTTCCAGTGCATCTGCATGCCCGGCTACGAGGGTGTGCACTGCGAGGTCAACAC AGACGAGTGTGCCAGCAGCCCCTGCCTGCACAATGGCCGCTGCCTGGACAAGATCAATGAGTTC CAGTGCGAGTGCCCCACGGGCTTCACTGGGCATCTGTGCCAGTACGATGTGGACGAGTGTGCCA GCACCCCCTGCAAGAATGGTGCCAAGTGCCTGGACGGACCCAACACTTACACCTGTGTGTGCAC GGAAGGGTACACGGGGACGCACTGCGAGGTGGACATCGATGAGTGCGACCCCGACCCCTGCCAC TACGGCTCCTGCAAGGACGGCGTCGCCACCTTCACCTGCCTCTGCCGCCCAGGCTACACGGGCC ACCACTGCGAGACCAACATCAACGAGTGCTCCAGCCAGCCCTGCCGCCACGGGGGCACCTGCCA GGACCGCGACAACGCCTACCTCTGCTTCTGCCTGAAGGGGACCACAGGACCCAACTGCGAGATC AACCTGGATGACTGTGCCAGCAGCCCCTGCGACTCGGGCACCTGTCTGGACAAGATCGATGGCT ACGAGTGTGCCTGTGAGCCGGGCTACACAGGGAGCATGTGTAACATCAACATCGATGAGTGTGC GGGCAACCCCTGCCACAACGGGGGCACCTGCGAGGACGGCATCAATGGCTTCACCTGCCGCTGC CCCGAGGGCTACCACGACCCCACCTGCCTGTCTGAGGTCAATGAGTGCAACAGCAACCCCTGCG TCCACGGGGCCTGCCGGGACAGCCTCAACGGGTACAAGTGCGACTGTGACCCTGGGTGGAGTGG GACCAACTGTGACATCAACAACAATGAGTGTGAATCCAACCCTTGTGTCAACGGCGGCACCTGC AAAGACATGACCAGTGGCTACGTGTGCACCTGCCGGGAGGGCTTCAGCGGTCCCAACTGCCAGA CCAACATCAACGAGTGTGCGTCCAACCCATGTCTGAACCAGGGCACGTGTATTGACGACGTTGC CGGGTACAAGTGCAACTGCCTGCTGCCCTACACAGGTGCCACGTGTGAGGTGGTGCTGGCCCCG TGTGCCCCCAGCCCCTGCAGAAACGGCGGGGAGTGCAGGCAATCCGAGGACTATGAGAGCTTCT CCTGTGTCTGCCCCACGGGCTGGCAAGGGCAGACCTGTGAGGTCGACATCAACGAGTGCGTTCT GAGCCCGTGCCGGCACGGCGCATCCTGCCAGAACACCCACGGCGGCTACCGCTGCCACTGCCAG GCCGGCTACAGTGGGCGCAACTGCGAGACCGACATCGACGACTGCCGGCCCAACCCGTGTCACA ACGGGGGCTCCTGCACAGACGGCATCAACACGGCCTTCTGCGACTGCCTGCCCGGCTTCCGGGG CACTTTCTGTGAGGAGGACATCAACGAGTGTGCCAGTGACCCCTGCCGCAACGGGGCCAACTGC ACGGACTGCGTGGACAGCTACACGTGCACCTGCCCCGCAGGCTTCAGCGGGATCCACTGTGAGA ACAACACGCCTGACTGCACAGAGAGCTCCTGCTTCAACGGTGGCACCTGCGTGGACGGCATCAA CTCGTTCACCTGCCTGTGTCCACCCGGCTTCACGGGCAGCTACTGCCAGCACGATGTCAATGAG TGCGACTCACAGCCCTGCCTGCATGGCGGCACCTGTCAGGACGGCTGCGGCTCCTACAGGTGCA CCTGCCCCCAGGGCTACACTGGCCCCAACTGCCAGAACCTTGTGCACTGGTGTGACTCCTCGCC CTGCAAGAACGGCGGCAAATGCTGGCAGACCCACACCCAGTACCGCTGCGAGTGCCCCAGCGGC TGGACCGGCCTTTACTGCGACGTGCCCAGCGTGTCCTGTGAGGTGGCTGCGCAGCGACAAGGTG TTGACGTTGCCCGCCTGTGCCAGCATGGAGGGCTCTGTGTGGACGCGGGCAACACGCACCACTG CCGCTGCCAGGCGGGCTACACAGGCAGCTACTGTGAGGACCTGGTGGACGAGTGCTCACCCAGC CCCTGCCAGAACGGGGCCACCTGCACGGACTACCTGGGCGGCTACTCCTGCAAGTGCGTGGCCG GCTACCACGGGGTGAACTGCTCTGAGGAGATCGACGAGTGCCTCTCCCACCCCTGCCAGAACGG GGGCACCTGCCTCGACCTCCCCAACACCTACAAGTGCTCCTGCCCACGGGGCACTCAGGGTGTG CACTGTGAGATCAACGTGGACGACTGCAATCCCCCCGTTGACCCCGTGTCCCGGAGCCCCAAGT GCTTTAACAACGGCACCTGCGTGGACCAGGTGGGCGGCTACAGCTGCACCTGCCCGCCGGGCTT CGTGGGTGAGCGCTGTGAGGGGGATGTCAACGAGTGCCTGTCCAATCCCTGCGACGCCCGTGGC ACCCAGAACTGCGTGCAGCGCGTCAATGACTTCCACTGCGAGTGCCGTGCTGGTCACACCGGGC GCCGCTGCGAGTCCGTCATCAATGGCTGCAAAGGCAAGCCCTGCAAGAATGGGGGCACCTGCGC CGTGGCCTCCAACACCGCCCGCGGGTTCATCTGCAAGTGCCCTGCGGGCTTCGAGGGCGCCACG TGTGAGAATGACGCTCGTACCTGCGGCAGCCTGCGCTGCCTCAACGGCGGCACATGCATCTCCG GCCCGCGCAGCCCCACCTGCCTGTGCCTGGGCCCCTTCACGGGCCCCGAATGCCAGTTCCCGGC CAGCAGCCCCTGCCTGGGCGGCAACCCCTGCTACAACCAGGGGACCTGTGAGCCCACATCCGAG AGCCCCTTCTACCGTTGCCTGTGCCCCGCCAAATTCAACGGGCTCTTGTGCCACATCCTGGACT ACAGCTTCGGGGGTGGGGCCGGGCGCGACATCCCCCCGCCGCTGATCGAGGAGGCGTGCGAGCT GCCCGAGTGCCAGGAGGACGCGGGCAACAAGGTCTGCAGCCTGCAGTGCAACAACCACGCGTGC GGCTGGGACGGCGGTGACTGCTCCCTCAACTTCAATGACCCCTGGAAGAACTGCACGCAGTCTC TGCAGTGCTGGAAGTACTTCAGTGACGGCCACTGTGACAGCCAGTGCAACTCAGCCGGCTGCCT CTTCGACGGCTTTGACTGCCAGCGTGCGGAAGGCCAGTGCAACCCCCTGTACGACCAGTACTGC AAGGACCACTTCAGCGACGGGCACTGCGACCAGGGCTGCAACAGCGCGGAGTGCGAGTGGGACG GGCTGGACTGTGCGGAGCATGTACCCGAGAGGCTGGCGGCCGGCACGCTGGTGGTGGTGGTGCT GATGCCGCCGGAGCAGCTGCGCAACAGCTCCTTCCACTTCCTGCGGGAGCTCAGCCGCGTGCTG CACACCAACGTGGTCTTCAAGCGTGACGCACACGGCCAGCAGATGATCTTCCCCTACTACGGCC GCGAGGAGGAGCTGCGCAAGCACCCCATCAAGCGTGCCGCCGAGGGCTGGGCCGCACCTGACGC CCTGCTGGGCCAGGTGAAGGCCTCGCTGCTCCCTGGTGGCAGCGAGGGTGGGCGGCGGCGGAGG GAGCTGGACCCCATGGACGTCCGCGGCTCCATCGTCTACCTGGAGATTGACAACCGGCAGTGTG TGCAGGCCTCCTCGCAGTGCTTCCAGAGTGCCACCGACGTGGCCGCATTCCTGGGAGCGCTCGC CTCGCTGGGCAGCCTCAACATCCCCTACAAGATCGAGGCCGTGCAGAGTGAGACCGTGGAGCCG CCCCCGCCGGCGCAGCTGCACTTCATGTACGTGGCGGCGGCCGCCTTTGTGCTTCTGTTCTTCG TGGGCTGCGGGGTGCTGCTGTCCCGCAAGCGCCGGCGGCAGCATGGCCAGCTCTGGTTCCCTGA GGGCTTCAAAGTGTCTGAGGCCAGCAAGAAGAAGCGGCGGGAGCCCCTCGGCGAGGACTCCGTG GGCCTCAAGCCCCTGAAGAACGCTTCAGACGGTGCCCTCATGGACGACAACCAGAATGAGTGGG GGGACGAGGACCTGGAGACCAAGAAGTTCCGGTTCGAGGAGCCCGTGGTTCTGCCTGACCTGGA CGACCAGACAGACCACCGGCAGTGGACTCAGCAGCACCTGGATGCCGCTGACCTGCGCATGTCT GCCATGGCCCCCACACCGCCCCAGGGTGAGGTTGACGCCGACTGCATGGACGTCAATGTCCGCG GGCCTGATGGCTTCACCCCGCTCATGATCGCCTCCTGCAGCGGGGGCGGCCTGGAGACGGGCAA CAGCGAGGAAGAGGAGGACGCGCCGGCCGTCATCTCCGACTTCATCTACCAGGGCGCCAGCCTG CACAACCAGACAGACCGCACGGGCGAGACCGCCTTGCACCTGGCCGCCCGCTACTCACGCTCTG ATGCCGCCAAGCGCCTGCTGGAGGCCAGCGCAGATGCCAACATCCAGGACAACATGGGCCGCAC CCCGCTGCATGCGGCTGTGTCTGCCGACGCACAAGGTGTCTTCCAGATCCTGATCCGGAACCGA GCCACAGACCTGGATGCCCGCATGCATGATGGCACGACGCCACTGATCCTGGCTGCCCGCCTGG CCGTGGAGGGCATGCTGGAGGACCTCATCAACTCACACGCCGACGTCAACGCCGTAGATGACCT GGGCAAGTCCGCCCTGCACTGGGCCGCCGCCGTGAACAATGTGGATGCCGCAGTTGTGCTCCTG AAGAACGGGGCTAACAAAGATATGCAGAACAACAGGGAGGAGACACCCCTGTTTCTGGCCGCCC GGGAGGGCAGCTACGAGACCGCCAAGGTGCTGCTGGACCACTTTGCCAACCGGGACATCACGGA TCATATGGACCGCCTGCCGCGCGACATCGCACAGGAGCGCATGCATCACGACATCGTGAGGCTG CTGGACGAGTACAACCTGGTGCGCAGCCCGCAGCTGCACGGAGCCCCGCTGGGGGGCACGCCCA CCCTGTCGCCCCCGCTCTGCTCGCCCAACGGCTACCTGGGCAGCCTCAAGCCCGGCGTGCAGGG CAAGAAGGTCCGCAAGCCCAGCAGCAAAGGCCTGGCCTGTGGAAGCAAGGAGGCCAAGGACCTC AAGGCACGGAGGAAGAAGTCCCAGGACGGCAAGGGCTGCCTGCTGGACAGCTCCGGCATGCTCT CGCCCGTGGACTCCCTGGAGTCACCCCATGGCTACCTGTCAGACGTGGCCTCGCCGCCACTGCT GCCCTCCCCGTTCCAGCAGTCTCCGTCCGTGCCCCTCAACCACCTGCCTGGGATGCCCGACACC CACCTGGGCATCGGGCACCTGAACGTGGCGGCCAAGCCCGAGATGGCGGCGCTGGGTGGGGGCG GCCGGCTGGCCTTTGAGACTGGCCCACCTCGTCTCTCCCACCTGCCTGTGGCCTCTGGCACCAG CACCGTCCTGGGCTCCAGCAGCGGAGGGGCCCTGAATTTCACTGTGGGCGGGTCCACCAGTTTG AATGGTCAATGCGAGTGGCTGTCCCGGCTGCAGAGCGGCATGGTGCCGAACCAATACAACCCTC TGCGGGGGAGTGTGGCACCAGGCCCCCTGAGCACACAGGCCCCCTCCCTGCAGCATGGCATGGT AGGCCCGCTGCACAGTAGCCTTGCTGCCAGCGCCCTGTCCCAGATGATGAGCTACCAGGGCCTG CCCAGCACCCGGCTGGCCACCCAGCCTCACCTGGTGCAGACCCAGCAGGTGCAGCCACAAAACT TACAGATGCAGCAGCAGAACCTGCAGCCAGCAAACATCCAGCAGCAGCAAAGCCTGCAGCCGCC ACCACCACCACCACAGCCGCACCTTGGCGTGAGCTCAGCAGCCAGCGGCCACCTGGGCCGGAGC TTCCTGAGTGGAGAGCCGAGCCAGGCAGACGTGCAGCCACTGGGCCCCAGCAGCCTGGCGGTGC ACACTATTCTGCCCCAGGAGAGCCCCGCCCTGCCCACGTCGCTGCCATCCTCGCTGGTCCCACC CGTGACCGCAGCCCAGTTCCTGACGCCCCCCTCGCAGCACAGCTACTCCTCGCCTGTGGACAAC ACCCCCAGCCACCAGCTACAGGTGCCTGAGCACCCCTTCCTCACCCCGTCCCCTGAGTCCCCTG ACCAGTGGTCCAGCTCGTCCCCGCATTCCAACGTCTCCGACTGGTCCGAGGGCGTCTCCAGCCC TCCCACCAGCATGCAGTCCCAGATCGCCCGCATTCCGGAGGCCTTCAAGTAAACGGCGCGCCCC ACGAGACCCCGGCTTCCTTTCCCAAGCCTTCGGGCGTCTGTGTGCGCTCTGTGGATGCCAGGGC CGACCAGAGGAGCCTTTTTAAAACACATGTTTTTATACAAAATAAGAACGAGGATTTTAATTTT TTTTAGTATTTATTTATGTACTTTTATTTTACACAGAAACACTGCCTTTTTATTTATATGTACT GTTTTATCTGGCCCCAGGTAGAAACTTTTATCTATTCTGAGAAAACAAGCAAGTTCTGAGAGCC AGGGTTTTCCTACGTAGGATGAAAAGATTCTTCTGTGTTTATAAAATATAAACAAAGATTCATG ATTTATAAATGCCATTTATTTATTGATTCCTTTTTTCAAAATCCAAAAAGAAATGATGTTGGAG AAGGGAAGTTGAACGAGCATAGTCCAAAAAGCTCCTGGGGCGTCCAGGCCGCGCCCTTTCCCCG ACGCCCACCCAACCCCAAGCCAGCCCGGCCGCTCCACCAGCATCACCTGCCTGTTAGGAGAAGC TGCATCCAGAGGCAAACGGAGGCAAAGCTGGCTCACCTTCCGCACGCGGATTAATTTGCATCTG AAATAGGAAACAAGTGAAAGCATATGGGTTAGATGTTGCCATGTGTTTTAGATGGTTTCTTGCA AGCATGCTTGTGAAAATGTGTTCTCGGAGTGTGTATGCCAAGAGTGCACCCATGGTACCAATCA TGAATCTTTGTTTCAGGTTCAGTATTATGTAGTTGTTCGTTGGTTATACAAGTTCTTGGTCCCT CCAGAACCACCCCGGCCCCCTGCCCGTTCTTGAAATGTAGGCATCATGCATGTCAAACATGAGA TGTGTGGACTGTGGCACTTGCCTGGGTCACACACGGAGGCATCCTACCCTTTTCTGGGGAAAGA CACTGCCTGGGCTGACCCCGGTGGCGGCCCCAGCACCTCAGCCTGCACAGTGTCCCCCAGGTTC CGAAGAAGATGCTCCAGCAACACAGCCTGGGCCCCAGCTCGCGGGACCCGACCCCCCGTGGGCT CCCGTGTTTTGTAGGAGACTTGCCAGAGCCGGGCACATTGAGCTGTGCAACGCCGTGGGCTGCG TCCTTTGGTCCTGTCCCCGCAGCCCTGGCAGGGGGCATGCGGTCGGGCAGGGGCTGGAGGGAGG CGGGGGCTGCCCTTGGGCCACCCCTCCTAGTTTGGGAGGAGCAGATTTTTGCAATACCAAGTAT AGCCTATGGCAGAAAAAATGTCTGTAAATATGTTTTTAAAGGTGGATTTTGTTTAAAAAATCTT AATGAATGAGTCTGTTGTGTGTCATGCCAGTGAGGGACGTCAGACTTGGCTCAGCTCGGGGAGC CTTAGCCGCCCATGCACTGGGGACGCTCCGCTGCCGTGCCGCCTGCACTCCTCAGGGCAGCCTC CCCCGGCTCTACGGGGGCCGCGTGGTGCCATCCCCAGGGGGCATGACCAGATGCGTCCCAAGAT GTTGATTTTTACTGTGTTTTATAAAATAGAGTGTAGTTTACAGAAAAAGACTTTAAAAGTGATC TACATGAGGAACTGTAGATGATGTATTTTTTTCATCTTTTTTGTTAACTGATTTGCAATAAAAA TGATACTGATGGTGAAAAAAAAAAAAAAA Download Select all
Length	9309

CDS Information

Location	join(1..61,1685..1763,21808..22070,22599..22937, 26222..26344,26963..27196,27495..27650,27850..28035, 28402..28515,29693..29806,30071..30304,30387..30497, 31085..31277,32250..32395,32653..32766,34516..34635, 34982..35134,35826..36054,36716..36917,37402..37555, 37648..37832,38350..38482,38814..39071,39148..39260, 39906..40477,40683..41114,42457..42605,43299..43515,
CDS Sequence	>gi\|148833507:1-7668 Homo sapiens notch 1 (NOTCH1), mRNA ATGCCGCCGCTCCTGGCGCCCCTGCTCTGCCTGGCGCTGCTGCCCGCGCTCGCCGCACGAGGCCCGCGAT GCTCCCAGCCCGGTGAGACCTGCCTGAATGGCGGGAAGTGTGAAGCGGCCAATGGCACGGAGGCCTGCGT CTGTGGCGGGGCCTTCGTGGGCCCGCGATGCCAGGACCCCAACCCGTGCCTCAGCACCCCCTGCAAGAAC GCCGGGACATGCCACGTGGTGGACCGCAGAGGCGTGGCAGACTATGCCTGCAGCTGTGCCCTGGGCTTCT CTGGGCCCCTCTGCCTGACACCCCTGGACAATGCCTGCCTCACCAACCCCTGCCGCAACGGGGGCACCTG CGACCTGCTCACGCTGACGGAGTACAAGTGCCGCTGCCCGCCCGGCTGGTCAGGGAAATCGTGCCAGCAG GCTGACCCGTGCGCCTCCAACCCCTGCGCCAACGGTGGCCAGTGCCTGCCCTTCGAGGCCTCCTACATCT GCCACTGCCCACCCAGCTTCCATGGCCCCACCTGCCGGCAGGATGTCAACGAGTGTGGCCAGAAGCCCGG GCTTTGCCGCCACGGAGGCACCTGCCACAACGAGGTCGGCTCCTACCGCTGCGTCTGCCGCGCCACCCAC ACTGGCCCCAACTGCGAGCGGCCCTACGTGCCCTGCAGCCCCTCGCCCTGCCAGAACGGGGGCACCTGCC GCCCCACGGGCGACGTCACCCACGAGTGTGCCTGCCTGCCAGGCTTCACCGGCCAGAACTGTGAGGAAAA TATCGACGATTGTCCAGGAAACAACTGCAAGAACGGGGGTGCCTGTGTGGACGGCGTGAACACCTACAAC TGCCGCTGCCCGCCAGAGTGGACAGGTCAGTACTGTACCGAGGATGTGGACGAGTGCCAGCTGATGCCAA ATGCCTGCCAGAACGGCGGGACCTGCCACAACACCCACGGTGGCTACAACTGCGTGTGTGTCAACGGCTG GACTGGTGAGGACTGCAGCGAGAACATTGATGACTGTGCCAGCGCCGCCTGCTTCCACGGCGCCACCTGC CATGACCGTGTGGCCTCCTTCTACTGCGAGTGTCCCCATGGCCGCACAGGTCTGCTGTGCCACCTCAACG ACGCATGCATCAGCAACCCCTGTAACGAGGGCTCCAACTGCGACACCAACCCTGTCAATGGCAAGGCCAT CTGCACCTGCCCCTCGGGGTACACGGGCCCGGCCTGCAGCCAGGACGTGGATGAGTGCTCGCTGGGTGCC AACCCCTGCGAGCATGCGGGCAAGTGCATCAACACGCTGGGCTCCTTCGAGTGCCAGTGTCTGCAGGGCT ACACGGGCCCCCGATGCGAGATCGACGTCAACGAGTGCGTCTCGAACCCGTGCCAGAACGACGCCACCTG CCTGGACCAGATTGGGGAGTTCCAGTGCATCTGCATGCCCGGCTACGAGGGTGTGCACTGCGAGGTCAAC ACAGACGAGTGTGCCAGCAGCCCCTGCCTGCACAATGGCCGCTGCCTGGACAAGATCAATGAGTTCCAGT GCGAGTGCCCCACGGGCTTCACTGGGCATCTGTGCCAGTACGATGTGGACGAGTGTGCCAGCACCCCCTG CAAGAATGGTGCCAAGTGCCTGGACGGACCCAACACTTACACCTGTGTGTGCACGGAAGGGTACACGGGG ACGCACTGCGAGGTGGACATCGATGAGTGCGACCCCGACCCCTGCCACTACGGCTCCTGCAAGGACGGCG TCGCCACCTTCACCTGCCTCTGCCGCCCAGGCTACACGGGCCACCACTGCGAGACCAACATCAACGAGTG CTCCAGCCAGCCCTGCCGCCACGGGGGCACCTGCCAGGACCGCGACAACGCCTACCTCTGCTTCTGCCTG AAGGGGACCACAGGACCCAACTGCGAGATCAACCTGGATGACTGTGCCAGCAGCCCCTGCGACTCGGGCA CCTGTCTGGACAAGATCGATGGCTACGAGTGTGCCTGTGAGCCGGGCTACACAGGGAGCATGTGTAACAT CAACATCGATGAGTGTGCGGGCAACCCCTGCCACAACGGGGGCACCTGCGAGGACGGCATCAATGGCTTC ACCTGCCGCTGCCCCGAGGGCTACCACGACCCCACCTGCCTGTCTGAGGTCAATGAGTGCAACAGCAACC CCTGCGTCCACGGGGCCTGCCGGGACAGCCTCAACGGGTACAAGTGCGACTGTGACCCTGGGTGGAGTGG GACCAACTGTGACATCAACAACAATGAGTGTGAATCCAACCCTTGTGTCAACGGCGGCACCTGCAAAGAC ATGACCAGTGGCTACGTGTGCACCTGCCGGGAGGGCTTCAGCGGTCCCAACTGCCAGACCAACATCAACG AGTGTGCGTCCAACCCATGTCTGAACCAGGGCACGTGTATTGACGACGTTGCCGGGTACAAGTGCAACTG CCTGCTGCCCTACACAGGTGCCACGTGTGAGGTGGTGCTGGCCCCGTGTGCCCCCAGCCCCTGCAGAAAC GGCGGGGAGTGCAGGCAATCCGAGGACTATGAGAGCTTCTCCTGTGTCTGCCCCACGGGCTGGCAAGGGC AGACCTGTGAGGTCGACATCAACGAGTGCGTTCTGAGCCCGTGCCGGCACGGCGCATCCTGCCAGAACAC CCACGGCGGCTACCGCTGCCACTGCCAGGCCGGCTACAGTGGGCGCAACTGCGAGACCGACATCGACGAC TGCCGGCCCAACCCGTGTCACAACGGGGGCTCCTGCACAGACGGCATCAACACGGCCTTCTGCGACTGCC TGCCCGGCTTCCGGGGCACTTTCTGTGAGGAGGACATCAACGAGTGTGCCAGTGACCCCTGCCGCAACGG GGCCAACTGCACGGACTGCGTGGACAGCTACACGTGCACCTGCCCCGCAGGCTTCAGCGGGATCCACTGT GAGAACAACACGCCTGACTGCACAGAGAGCTCCTGCTTCAACGGTGGCACCTGCGTGGACGGCATCAACT CGTTCACCTGCCTGTGTCCACCCGGCTTCACGGGCAGCTACTGCCAGCACGATGTCAATGAGTGCGACTC ACAGCCCTGCCTGCATGGCGGCACCTGTCAGGACGGCTGCGGCTCCTACAGGTGCACCTGCCCCCAGGGC TACACTGGCCCCAACTGCCAGAACCTTGTGCACTGGTGTGACTCCTCGCCCTGCAAGAACGGCGGCAAAT GCTGGCAGACCCACACCCAGTACCGCTGCGAGTGCCCCAGCGGCTGGACCGGCCTTTACTGCGACGTGCC CAGCGTGTCCTGTGAGGTGGCTGCGCAGCGACAAGGTGTTGACGTTGCCCGCCTGTGCCAGCATGGAGGG CTCTGTGTGGACGCGGGCAACACGCACCACTGCCGCTGCCAGGCGGGCTACACAGGCAGCTACTGTGAGG ACCTGGTGGACGAGTGCTCACCCAGCCCCTGCCAGAACGGGGCCACCTGCACGGACTACCTGGGCGGCTA CTCCTGCAAGTGCGTGGCCGGCTACCACGGGGTGAACTGCTCTGAGGAGATCGACGAGTGCCTCTCCCAC CCCTGCCAGAACGGGGGCACCTGCCTCGACCTCCCCAACACCTACAAGTGCTCCTGCCCACGGGGCACTC AGGGTGTGCACTGTGAGATCAACGTGGACGACTGCAATCCCCCCGTTGACCCCGTGTCCCGGAGCCCCAA GTGCTTTAACAACGGCACCTGCGTGGACCAGGTGGGCGGCTACAGCTGCACCTGCCCGCCGGGCTTCGTG GGTGAGCGCTGTGAGGGGGATGTCAACGAGTGCCTGTCCAATCCCTGCGACGCCCGTGGCACCCAGAACT GCGTGCAGCGCGTCAATGACTTCCACTGCGAGTGCCGTGCTGGTCACACCGGGCGCCGCTGCGAGTCCGT CATCAATGGCTGCAAAGGCAAGCCCTGCAAGAATGGGGGCACCTGCGCCGTGGCCTCCAACACCGCCCGC GGGTTCATCTGCAAGTGCCCTGCGGGCTTCGAGGGCGCCACGTGTGAGAATGACGCTCGTACCTGCGGCA GCCTGCGCTGCCTCAACGGCGGCACATGCATCTCCGGCCCGCGCAGCCCCACCTGCCTGTGCCTGGGCCC CTTCACGGGCCCCGAATGCCAGTTCCCGGCCAGCAGCCCCTGCCTGGGCGGCAACCCCTGCTACAACCAG GGGACCTGTGAGCCCACATCCGAGAGCCCCTTCTACCGTTGCCTGTGCCCCGCCAAATTCAACGGGCTCT TGTGCCACATCCTGGACTACAGCTTCGGGGGTGGGGCCGGGCGCGACATCCCCCCGCCGCTGATCGAGGA GGCGTGCGAGCTGCCCGAGTGCCAGGAGGACGCGGGCAACAAGGTCTGCAGCCTGCAGTGCAACAACCAC GCGTGCGGCTGGGACGGCGGTGACTGCTCCCTCAACTTCAATGACCCCTGGAAGAACTGCACGCAGTCTC TGCAGTGCTGGAAGTACTTCAGTGACGGCCACTGTGACAGCCAGTGCAACTCAGCCGGCTGCCTCTTCGA CGGCTTTGACTGCCAGCGTGCGGAAGGCCAGTGCAACCCCCTGTACGACCAGTACTGCAAGGACCACTTC AGCGACGGGCACTGCGACCAGGGCTGCAACAGCGCGGAGTGCGAGTGGGACGGGCTGGACTGTGCGGAGC ATGTACCCGAGAGGCTGGCGGCCGGCACGCTGGTGGTGGTGGTGCTGATGCCGCCGGAGCAGCTGCGCAA CAGCTCCTTCCACTTCCTGCGGGAGCTCAGCCGCGTGCTGCACACCAACGTGGTCTTCAAGCGTGACGCA CACGGCCAGCAGATGATCTTCCCCTACTACGGCCGCGAGGAGGAGCTGCGCAAGCACCCCATCAAGCGTG CCGCCGAGGGCTGGGCCGCACCTGACGCCCTGCTGGGCCAGGTGAAGGCCTCGCTGCTCCCTGGTGGCAG CGAGGGTGGGCGGCGGCGGAGGGAGCTGGACCCCATGGACGTCCGCGGCTCCATCGTCTACCTGGAGATT GACAACCGGCAGTGTGTGCAGGCCTCCTCGCAGTGCTTCCAGAGTGCCACCGACGTGGCCGCATTCCTGG GAGCGCTCGCCTCGCTGGGCAGCCTCAACATCCCCTACAAGATCGAGGCCGTGCAGAGTGAGACCGTGGA GCCGCCCCCGCCGGCGCAGCTGCACTTCATGTACGTGGCGGCGGCCGCCTTTGTGCTTCTGTTCTTCGTG GGCTGCGGGGTGCTGCTGTCCCGCAAGCGCCGGCGGCAGCATGGCCAGCTCTGGTTCCCTGAGGGCTTCA AAGTGTCTGAGGCCAGCAAGAAGAAGCGGCGGGAGCCCCTCGGCGAGGACTCCGTGGGCCTCAAGCCCCT GAAGAACGCTTCAGACGGTGCCCTCATGGACGACAACCAGAATGAGTGGGGGGACGAGGACCTGGAGACC AAGAAGTTCCGGTTCGAGGAGCCCGTGGTTCTGCCTGACCTGGACGACCAGACAGACCACCGGCAGTGGA CTCAGCAGCACCTGGATGCCGCTGACCTGCGCATGTCTGCCATGGCCCCCACACCGCCCCAGGGTGAGGT TGACGCCGACTGCATGGACGTCAATGTCCGCGGGCCTGATGGCTTCACCCCGCTCATGATCGCCTCCTGC AGCGGGGGCGGCCTGGAGACGGGCAACAGCGAGGAAGAGGAGGACGCGCCGGCCGTCATCTCCGACTTCA TCTACCAGGGCGCCAGCCTGCACAACCAGACAGACCGCACGGGCGAGACCGCCTTGCACCTGGCCGCCCG CTACTCACGCTCTGATGCCGCCAAGCGCCTGCTGGAGGCCAGCGCAGATGCCAACATCCAGGACAACATG GGCCGCACCCCGCTGCATGCGGCTGTGTCTGCCGACGCACAAGGTGTCTTCCAGATCCTGATCCGGAACC GAGCCACAGACCTGGATGCCCGCATGCATGATGGCACGACGCCACTGATCCTGGCTGCCCGCCTGGCCGT GGAGGGCATGCTGGAGGACCTCATCAACTCACACGCCGACGTCAACGCCGTAGATGACCTGGGCAAGTCC GCCCTGCACTGGGCCGCCGCCGTGAACAATGTGGATGCCGCAGTTGTGCTCCTGAAGAACGGGGCTAACA AAGATATGCAGAACAACAGGGAGGAGACACCCCTGTTTCTGGCCGCCCGGGAGGGCAGCTACGAGACCGC CAAGGTGCTGCTGGACCACTTTGCCAACCGGGACATCACGGATCATATGGACCGCCTGCCGCGCGACATC GCACAGGAGCGCATGCATCACGACATCGTGAGGCTGCTGGACGAGTACAACCTGGTGCGCAGCCCGCAGC TGCACGGAGCCCCGCTGGGGGGCACGCCCACCCTGTCGCCCCCGCTCTGCTCGCCCAACGGCTACCTGGG CAGCCTCAAGCCCGGCGTGCAGGGCAAGAAGGTCCGCAAGCCCAGCAGCAAAGGCCTGGCCTGTGGAAGC AAGGAGGCCAAGGACCTCAAGGCACGGAGGAAGAAGTCCCAGGACGGCAAGGGCTGCCTGCTGGACAGCT CCGGCATGCTCTCGCCCGTGGACTCCCTGGAGTCACCCCATGGCTACCTGTCAGACGTGGCCTCGCCGCC ACTGCTGCCCTCCCCGTTCCAGCAGTCTCCGTCCGTGCCCCTCAACCACCTGCCTGGGATGCCCGACACC CACCTGGGCATCGGGCACCTGAACGTGGCGGCCAAGCCCGAGATGGCGGCGCTGGGTGGGGGCGGCCGGC TGGCCTTTGAGACTGGCCCACCTCGTCTCTCCCACCTGCCTGTGGCCTCTGGCACCAGCACCGTCCTGGG CTCCAGCAGCGGAGGGGCCCTGAATTTCACTGTGGGCGGGTCCACCAGTTTGAATGGTCAATGCGAGTGG CTGTCCCGGCTGCAGAGCGGCATGGTGCCGAACCAATACAACCCTCTGCGGGGGAGTGTGGCACCAGGCC CCCTGAGCACACAGGCCCCCTCCCTGCAGCATGGCATGGTAGGCCCGCTGCACAGTAGCCTTGCTGCCAG CGCCCTGTCCCAGATGATGAGCTACCAGGGCCTGCCCAGCACCCGGCTGGCCACCCAGCCTCACCTGGTG CAGACCCAGCAGGTGCAGCCACAAAACTTACAGATGCAGCAGCAGAACCTGCAGCCAGCAAACATCCAGC AGCAGCAAAGCCTGCAGCCGCCACCACCACCACCACAGCCGCACCTTGGCGTGAGCTCAGCAGCCAGCGG CCACCTGGGCCGGAGCTTCCTGAGTGGAGAGCCGAGCCAGGCAGACGTGCAGCCACTGGGCCCCAGCAGC CTGGCGGTGCACACTATTCTGCCCCAGGAGAGCCCCGCCCTGCCCACGTCGCTGCCATCCTCGCTGGTCC CACCCGTGACCGCAGCCCAGTTCCTGACGCCCCCCTCGCAGCACAGCTACTCCTCGCCTGTGGACAACAC CCCCAGCCACCAGCTACAGGTGCCTGAGCACCCCTTCCTCACCCCGTCCCCTGAGTCCCCTGACCAGTGG TCCAGCTCGTCCCCGCATTCCAACGTCTCCGACTGGTCCGAGGGCGTCTCCAGCCCTCCCACCAGCATGC AGTCCCAGATCGCCCGCATTCCGGAGGCCTTCAAGTAA Download Select all
CCDS ID	CCDS43905.1

Protein Information

Protein ID	NP_060087.3
Protein Name	Notch homolog 1, translocation-associated (Drosophila)
Molecular Wt. (Da)	270694
Protein Sequence	>4851 MPPLLAPLLCLALLPALAARGPRCSQPGETCLNGGKCEAANGTEACVCGGAFVGPRCQDPNPCL STPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCR CPPGWSGKSCQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHG GTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEE NIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYN CVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEG SNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPR CEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEF QCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCH YGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEI NLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRC PEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTC KDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAP CAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQ AGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANC TDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNE CDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSG WTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPS PCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGV HCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARG TQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGAT CENDARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSE SPFYRCLCPAKFNGLLCHILDYSFGGGAGRDIPPPLIEEACELPECQEDAGNKVCSLQCNNHAC GWDGGDCSLNFNDPWKNCTQSLQCWKYFSDGHCDSQCNSAGCLFDGFDCQRAEGQCNPLYDQYC KDHFSDGHCDQGCNSAECEWDGLDCAEHVPERLAAGTLVVVVLMPPEQLRNSSFHFLRELSRVL HTNVVFKRDAHGQQMIFPYYGREEELRKHPIKRAAEGWAAPDALLGQVKASLLPGGSEGGRRRR ELDPMDVRGSIVYLEIDNRQCVQASSQCFQSATDVAAFLGALASLGSLNIPYKIEAVQSETVEP PPPAQLHFMYVAAAAFVLLFFVGCGVLLSRKRRRQHGQLWFPEGFKVSEASKKKRREPLGEDSV GLKPLKNASDGALMDDNQNEWGDEDLETKKFRFEEPVVLPDLDDQTDHRQWTQQHLDAADLRMS AMAPTPPQGEVDADCMDVNVRGPDGFTPLMIASCSGGGLETGNSEEEEDAPAVISDFIYQGASL HNQTDRTGETALHLAARYSRSDAAKRLLEASADANIQDNMGRTPLHAAVSADAQGVFQILIRNR ATDLDARMHDGTTPLILAARLAVEGMLEDLINSHADVNAVDDLGKSALHWAAAVNNVDAAVVLL KNGANKDMQNNREETPLFLAAREGSYETAKVLLDHFANRDITDHMDRLPRDIAQERMHHDIVRL LDEYNLVRSPQLHGAPLGGTPTLSPPLCSPNGYLGSLKPGVQGKKVRKPSSKGLACGSKEAKDL KARRKKSQDGKGCLLDSSGMLSPVDSLESPHGYLSDVASPPLLPSPFQQSPSVPLNHLPGMPDT HLGIGHLNVAAKPEMAALGGGGRLAFETGPPRLSHLPVASGTSTVLGSSSGGALNFTVGGSTSL NGQCEWLSRLQSGMVPNQYNPLRGSVAPGPLSTQAPSLQHGMVGPLHSSLAASALSQMMSYQGL PSTRLATQPHLVQTQQVQPQNLQMQQQNLQPANIQQQQSLQPPPPPPQPHLGVSSAASGHLGRS FLSGEPSQADVQPLGPSSLAVHTILPQESPALPTSLPSSLVPPVTAAQFLTPPSQHSYSSPVDN TPSHQLQVPEHPFLTPSPESPDQWSSSSPHSNVSDWSEGVSSPPTSMQSQIARIPEAFK Download Select all
Length	2555
Uniprot ID	O15247
Ensembl Protein ID	ENSP00000358460

Post-translational Modification Information (Source : HPRD)

Residue	Type	site
A	Proteolytic Cleavage	1720
G	Proteolytic Cleavage	1753
R	Proteolytic Cleavage	1664
A	Proteolytic Cleavage	1720
T	Phosphorylation	1861

Enzyme Information

No matching records could be found.

PPi Information

(Click to view network : Source STRING) View

Interactant Gene ID (Source: HPRD)	Gene Symbol	HPRD ID	Ref Seq ID	Technique	References
331	XIAP	2094	NP_001158.2	in vitro;in vivo	17318174
867	CBL	1320	NP_005179.2	in vivo	11777909
2033	EP300	4078	NP_001420.2	in vitro;in vivo	11604511
2647	BLOC1S1	3263	NP_001478.1	in vivo	10747963
3516	RBPJ	920	NP_005340.2	in vitro;in vivo;yeast 2-hybrid	874 939 491 110 401 000 000 000 000 000
3932	LCK	1080	NP_005347.3	in vivo	14583609
4208	MEF2C	2809	NP_002388.2	in vivo	10082551
4790	NFKB1	1238	NP_003989.2	in vitro;in vivo	86 423 131 141 866 200 000 000
4856	NOV	1291	NP_002505.1	in vivo	12050162
5664	PSEN2	2860	NP_000438.2	in vivo	11518718
5949	RBP3	1581	NP_002891.1	in vivo	11511084
5970	RELA	1241	NP_068810.3	in vivo	8642313
8328	GFI1B	5088	NP_004179.3	yeast 2-hybrid	16713569
9253	NUMBL	4931	NP_004747.1	in vitro;yeast 2-hybrid	9169836
23509	POFUT1	6319	NP_056167.1	in vivo	12697902
51176	LEF1	1075	NP_057353.1	in vitro;in vivo	11604490

Pathway Information

Pathway Name	Pathway ID
Dorso-ventral axis formation	hsa04320
MicroRNAs in cancer	hsa05206
Notch signaling pathway	hsa04330
Prion diseases	hsa05020
Thyroid hormone signaling pathway	hsa04919

Structure Information

PDB ID	1PB5
Resolution	-
Method	solution NMR
Chains	A
Molecule	Neurogenic locus notch homolog protein 1
Model	View

Domain Information

ID	Location	Description
cd00204	1922-2034	ANK
cl02529	1922-2034	ANK superfamily
cd00204	1989-2113	ANK
cl02529	1989-2113	ANK superfamily
cd00054	869-905	EGF_CA
cl21504	869-905	EGF_CA superfamily
cd00054	412-450	EGF_CA
cl21504	412-450	EGF_CA superfamily
cd00054	678-713	EGF_CA
cl21504	678-713	EGF_CA superfamily
cd00054	1021-1057	EGF_CA
cl21504	1021-1057	EGF_CA superfamily
cd00054	528-564	EGF_CA
cl21504	528-564	EGF_CA superfamily
cd00054	1184-1219	EGF_CA
cl21504	1184-1219	EGF_CA superfamily
cd00054	295-332	EGF_CA
cl21504	295-332	EGF_CA superfamily
cd00054	452-488	EGF_CA
cl21504	452-488	EGF_CA superfamily
cd00054	945-981	EGF_CA
cl21504	945-981	EGF_CA superfamily
cd00054	1146-1180	EGF_CA
cl21504	1146-1180	EGF_CA superfamily
cd00054	178-216	EGF_CA
cl21504	178-216	EGF_CA superfamily
cd00054	791-827	EGF_CA
cl21504	791-827	EGF_CA superfamily
cd00054	907-943	EGF_CA
cl21504	907-943	EGF_CA superfamily
cd00054	1238-1265	EGF_CA
cl21504	1238-1265	EGF_CA superfamily
cd00054	755-789	EGF_CA
cl21504	755-789	EGF_CA superfamily
cd00054	988-1019	EGF_CA
cl21504	988-1019	EGF_CA superfamily
cd00054	490-526	EGF_CA
cl21504	490-526	EGF_CA superfamily
cd00054	566-601	EGF_CA
cl21504	566-601	EGF_CA superfamily
cd00054	257-293	EGF_CA
cl21504	257-293	EGF_CA superfamily
cd00054	603-639	EGF_CA
cl21504	603-639	EGF_CA superfamily
cd00054	1267-1305	EGF_CA
cl21504	1267-1305	EGF_CA superfamily
cd00054	717-750	EGF_CA
cl21504	717-750	EGF_CA superfamily
cd00054	142-175	EGF_CA
cl21504	142-175	EGF_CA superfamily
cd00054	335-370	EGF_CA
cl21504	335-370	EGF_CA superfamily
cd00054	1064-1094	EGF_CA
cl21504	1064-1094	EGF_CA superfamily
cd00054	223-255	EGF_CA
cl21504	223-255	EGF_CA superfamily
pfam11936	2480-2541	DUF3454
cl13387	2480-2541	DUF3454 superfamily
pfam06816	1566-1621	NOD
cl08449	1566-1621	NOD superfamily
pfam07684	1670-1731	NODP
cl06639	1670-1731	NODP superfamily
cd00204	1875-2015	ANK
cd00204	1873-1981	ANK
cd00204	2022-2117	ANK
pfam00066	1485-1522	Notch
cl02419	1485-1522	Notch superfamily
pfam00066	1525-1561	Notch
cl02419	1525-1561	Notch superfamily
smart00004	1485-1521	NL
smart00004	1521-1561	NL
smart00179	869-905	EGF_CA
smart00004	1442-1479	NL
cl02419	1442-1479	Notch superfamily
smart00179	412-450	EGF_CA
smart00179	678-710	EGF_CA
smart00179	1183-1219	EGF_CA
smart00179	945-981	EGF_CA
smart00179	1021-1057	EGF_CA
smart00179	295-332	EGF_CA
smart00179	452-488	EGF_CA
smart00179	528-564	EGF_CA
smart00179	178-216	EGF_CA
pfam00023	1928-1959	Ank
pfam00066	1452-1480	Notch
pfam07645	412-444	EGF_CA
smart00179	1146-1180	EGF_CA
smart00179	791-827	EGF_CA
pfam07645	295-327	EGF_CA
smart00179	907-943	EGF_CA
smart00179	603-639	EGF_CA
smart00179	755-789	EGF_CA
smart00179	490-526	EGF_CA
smart00179	1238-1265	EGF_CA
smart00179	992-1019	EGF_CA
pfam00023	2062-2092	Ank
cd00053	1026-1055	EGF
smart00179	566-601	EGF_CA
pfam13606	1928-1956	Ank_3
smart00179	257-293	EGF_CA
smart00179	335-364	EGF_CA
cd00053	681-712	EGF
cd00053	298-330	EGF
pfam00008	1029-1055	EGF
smart00179	716-751	EGF_CA
pfam07645	178-208	EGF_CA
pfam00023	1994-2026	Ank
cd00053	1233-1263	EGF
cd00053	415-448	EGF
pfam00008	685-712	EGF
pfam12796	1932-2025	Ank_2
pfam13637	2063-2113	Ank_4
COG0666	1931-2121	ANKYR
COG0666	1920-2092	ANKYR
COG0666	1918-2093	ANKYR
PHA02878	1917-2089	PHA02878
PHA03095	1873-2081	PHA03095
pfam12796	1930-1991	Ank_2
PHA03095	1873-2033	PHA03095
PHA03095	1914-2086	PHA03095
PHA02875	1922-2113	PHA02875
COG0666	1873-1982	ANKYR
PHA03095	1945-2086	PHA03095
PHA02876	1922-2116	PHA02876
pfam13857	1917-1968	Ank_5
PHA03100	1873-2026	PHA03100
PHA03100	1932-2113	PHA03100
PLN03192	1924-2062	PLN03192
pfam12796	1874-1958	Ank_2
pfam13637	1930-1981	Ank_4
PHA02874	1922-2110	PHA02874
pfam12796	2047-2113	Ank_2
PHA02876	1910-2114	PHA02876
pfam13857	1947-2002	Ank_5
PHA02874	1942-2086	PHA02874
PHA03100	1914-2095	PHA03100
pfam06247	427-561	Plasmod_Pvs28
PHA02874	1970-2115	PHA02874
PTZ00322	1922-1990	PTZ00322
PHA02878	1909-2116	PHA02878
PTZ00322	2047-2116	PTZ00322
PHA02946	1879-2033	PHA02946
pfam06247	1241-1397	Plasmod_Pvs28
PHA02874	1930-2113	PHA02874
PHA02917	1922-1970	PHA02917
PLN03192	1979-2113	PLN03192
PHA02743	1913-2030	PHA02743
PTZ00322	1933-2004	PTZ00322

Ontology Information

HPRD ID	3101
Molecular Class	Cell surface receptor
Molecular Function	Receptor activity (GO:0004872)
Biological Process	Cell communication (GO:0007154); Signal transduction (GO:0007165)

SNP Information

View SNP Geneview Report

Drug Information

No matching records could be found.

External Links

ArrayExpress GO
ICGC GO
Cancer3D GO
COSMIC GO
NCG GO
TSGene GO
Tumor Gene Family of Databases GO
CCDB GO
G2SBC GO
Osteosarcoma Database GO
RCDB GO

ArrayExpress	GO
ICGC	GO
Cancer3D	GO
COSMIC	GO
NCG	GO
TSGene	GO
Tumor Gene Family of Databases	GO
CCDB	GO
G2SBC	GO
Osteosarcoma Database	GO
RCDB	GO