Search results:


General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
PLS1 5357 Plastin 1 (I isoform)  3- 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
20089989   2010Cell line : -

Source : VU University Medical Center, Amsterdam, The Netherlands.

Sample Type : CRC tumor and normal tissue

No. of Sample : -

Stage : -

Biochemical isolation to nano-LC-MS/MS analysisUnknown--


Gene Details



Chromosome: 3; NC_000003.11 (142315229..142432506)

View Larger Image
   
Gene Type protein coding
Gene Family EF-hand domain containing
Description Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. The protein encoded by this gene is a third distinct plastin isoform, which is specifically expressed at high levels in the small intestine. Alternatively spliced transcript variants varying in the 5' UTR, but encoding the same protein, have been found for this gene. A pseudogene of this gene is found on chromosome 11.[provided by RefSeq, Feb 2010]  
Chromosome 3
Location 3q23
Start 142596387  
End 142713664  
Strand +  
Gene Sequence

   Download   Select all

Length 117278  
OMIM ID 602734   
HGNC ID HGNC:9090   
Unigene ID Hs.203637    
Ensembl ID ENSG00000120756   
PharmGKB ID PA33417   

mRNA Information


mRNA ID NM_001145319.1
Exon join(1..123,67816..67921,73004..73167,74607..74736, 79771..79903,81646..81727,87620..87785,87867..88009, 89898..89990,93232..93427,98083..98161,101567..101681, 107482..107615,108077..108200,115115..115239, 115486..117278)  
mRNA Sequence

   Download   Select all

Length 3720  



CDS Information


   
Location join(67852..67921,73004..73167,74607..74736,79771..79903, 81646..81727,87620..87785,87867..88009,89898..89990, 93232..93427,98083..98161,101567..101681,107482..107615, 108077..108200,115115..115239,115486..115621)
CDS Sequence

   Download   Select all

CCDS ID CCDS3125.1



Protein Information


      
Protein IDNP_001138791.1
Protein NamePlastin 1 (I isoform)
Molecular Wt. (Da)70123
Protein Sequence

   Download   Select all

Length 629  
Uniprot IDO14493
Ensembl Protein ID ENSP00000342445  



Post-translational Modification Information (Source : HPRD)


No matching records could be found.

Enzyme Information


No matching records could be found.

PPi Information


(Click to view network : Source STRING)      View   

No matching records from HPRD source could be found.

Pathway Information


No matching records could be found.

Structure Information


No matching records could be found.

Domain Information




ID Location Description
cd00014123-238  CH
cl00030123-238  CH superfamily
cd00014267-376  CH
cl00030267-376  CH superfamily
cd0005115-81  EFh
cl0830215-81  EFh superfamily
pfam00307269-376  CH
smart00033127-234  CH
pfam00307127-237  CH
smart00033399-502  CH
cl00030399-502  CH superfamily
smart00033270-372  CH
pfam00307398-503  CH
pfam00307519-624  CH
cl00030519-624  CH superfamily
smart00033520-621  CH
cd0005217-80  EH
cd00014519-625  CH
cd0021335-83  S-100
pfam1383314-83  EF-hand_8
cd00014397-503  CH
smart0005456-83  EFh
cl2334756-83  EFh superfamily
cd0503127-80  S-100A10_like
pfam0003656-83  EF-hand_1
cl2348956-83  EF-hand_1 superfamily
cd0502531-83  S-100A1
smart0005415-42  EFh
pfam1340515-42  EF-hand_6
cl2363415-42  EF-hand_6 superfamily
pfam0003615-42  EF-hand_1
pfam1320256-80  EF-hand_5
cl2363256-80  EF-hand_5 superfamily
cd0005156-95  EFh
COG506913-621  SAC6
pfam1349922-80  EF-hand_7
COG5126Apr-88  FRQ1
COG5126Mar-90  FRQ1
COG5069388-595  SAC6
PTZ0018414-80  PTZ00184
PTZ00183Mar-93  PTZ00183
smart00027Aug-80  EH
PTZ00183Oct-80  PTZ00183
PTZ00184Aug-87  PTZ00184


Ontology Information


   
HPRD ID7520
Molecular ClassCytoskeletal protein
Molecular FunctionTransporter activity (GO:0005215)
Biological ProcessTransport (GO:0006810)  



SNP Information


View SNP Geneview Report   

Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO