CoReCG

Evidence Information

Pubmed ID	Year	Sample Information	Techniques	Mechanism	Fold Change	Remark
20811717	2010	Cell line : - Source : - Sample Type : - No. of Sample : - Stage : -	-	Up-regulation	-	Overexpression of Pak1 increased colorectal cancer cell motility and invasion.
22733437	2013	Cell line : - Source : - Sample Type : CRC tumor No. of Sample : 183 Stage : TNM Stage I,II,III,IV	Immunohistochemistry	Up-regulation	-	-

Gene Details

NC_000008.10 (141668481..142011412, complement)
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Gene Type	protein coding
Gene Family	Serine/threonine phosphatases / Protein phosphatase 1, regulatory subunits
Description	This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene, but the full-length natures of only four of them have been determined. [provided by RefSeq, Oct 2015]
Chromosome	8
Location	8q24.3
Start	141668481
End	142011412
Strand	-
Gene Sequence	Download   Select all
Length	342932
OMIM ID	600758
HGNC ID	HGNC:9611
Unigene ID	Hs.395482
Ensembl ID	ENSG00000169398
PharmGKB ID	PA33955

mRNA Information

mRNA ID	?NM_001199649.1
Exon	join(1..189,75565..75653,110545..110771,121677..121843, 136915..137002,154636..154715,154992..155054, 170788..170842,182294..182434,182960..183037, 197664..197771,200738..200855,207930..207960, 211788..211840,237024..237080,240052..240149, 248998..249082,254454..254554,256547..256662, 257984..258084,262207..262296,265859..266063, 283605..283716,295109..295195,298607..298744, 300292..300423,314620..314682,325815..325854, 326910..327016,332890..333045,336317..336397, 341636..342932)
mRNA Sequence	Download   Select all
Length	4561

CDS Information

   

Location	311..3469
CDS Sequence	Download   Select all
CCDS ID	CCDS56557.1

Protein Information

      

Protein ID	NP_001186578.1
Protein Name	protein tyrosine kinase 2
Molecular Wt. (Da)	0
Protein Sequence	Download   Select all
Length	1052
Uniprot ID	Q92945
Ensembl Protein ID	ENSP00000381216

Post-translational Modification Information (Source : HPRD)

Residue	Type	site
K	Sumoylation	153
S	Phosphorylation	744
S	Phosphorylation	862
S	Phosphorylation	865
S	Phosphorylation	932
K	Sumoylation	131
S	Phosphorylation	722
S	Phosphorylation	840
S	Phosphorylation	843
S	Phosphorylation	910
Y	Phosphorylation	429
Y	Phosphorylation	598
Y	Phosphorylation	599
Y	Phosphorylation	883
Y	Phosphorylation	947
Y	Phosphorylation	407
Y	Phosphorylation	576
Y	Phosphorylation	577
Y	Phosphorylation	861
Y	Phosphorylation	925
Y	Dephosphorylation	419
Y	Dephosphorylation	397
Y	Phosphorylation	397
Y	Phosphorylation	861
Y	Phosphorylation	419
Y	Phosphorylation	947
Y	Phosphorylation	397
Y	Phosphorylation	925
Y	Dephosphorylation	419
Y	Dephosphorylation	397
D	Proteolytic Cleavage	726
D	Proteolytic Cleavage	704
Y	Phosphorylation	598
Y	Phosphorylation	599
Y	Phosphorylation	576
Y	Phosphorylation	577
Y	Phosphorylation	397
Y	Phosphorylation	598
Y	Phosphorylation	599
Y	Phosphorylation	576
Y	Phosphorylation	577
Y	Phosphorylation	429
Y	Phosphorylation	407
Y	Phosphorylation	577
S	Phosphorylation	51;-
S	Phosphorylation	29;-
S	Phosphorylation	850;-
S	Phosphorylation	872;-
S	Phosphorylation	390;-
S	Phosphorylation	412;-
Y	Phosphorylation	1016;-
Y	Phosphorylation	1038;-
T	Phosphorylation	936;-
T	Phosphorylation	914;-
S	Phosphorylation	914
S	Phosphorylation	892
T	Phosphorylation	35
T	Phosphorylation	13
S	Phosphorylation	909
S	Phosphorylation	887
S	Phosphorylation	590
S	Phosphorylation	568
T	Phosphorylation	408
T	Phosphorylation	386
Y	Phosphorylation	592
Y	Phosphorylation	570
S	Phosphorylation	727
S	Phosphorylation	705
S	Phosphorylation	738
S	Phosphorylation	716
T	Phosphorylation	46
T	Phosphorylation	24
S	Phosphorylation	38
S	Phosphorylation	16

Enzyme Information

No matching records could be found.

PPi Information

(Click to view network : Source STRING)      View   

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        

Interactant Gene ID (Source: HPRD)	Gene Symbol	HPRD ID	Ref Seq ID	Technique	References
87	ACTN1	20	NP_001123476.1	in vivo	11369769
660	BMX	2111	NP_975010.1	in vitro;in vivo	11331870
1445	CSK	496	NP_004374.1	in vitro;in vivo	7529872
1630	DCC	391	NP_005206.2	in vitro;in vivo	15494733
1956	EGFR	579	NP_005219.2	in vitro;in vivo	10806474
1969	EPHA2	1494	NP_004422.2	in vivo	10655584
2064	ERBB2	1281	NP_004439.2	in vivo	11807823
2065	ERBB3	1820	NP_001973.2	in vivo	11807823
2268	FGR	1288	NP_005239.1	in vivo	12387730
2321	FLT1	1297	NP_002010.2	in vivo	12023386
2534	FYN	655	NP_002028.1	in vitro	11278857
2885	GRB2	150	NP_002077.1	in vitro;in vivo	7997267
3667	IRS1	943	NP_005535.1	yeast 2-hybrid	9822703
3685	ITGAV	1903	NP_002201.1	in vitro	11927607
3688	ITGB1	628	NP_391987.1	in vitro	8649427
3689	ITGB2	2506	NP_000202.2	in vitro	8649427
3690	ITGB3	1428	NP_000203.2	in vitro;in vivo	8649427
3717	JAK2	993	NP_004963.1	in vivo	955   313   110   925   297
4067	LYN	1301	NP_002341.1	in vivo	11389892
4756	NEO1	3549	NP_002490.2	in vitro	15494733
5159	PDGFRB	1423	NP_002600.1	in vitro;in vivo	10806474
5295	PIK3R1	1381	NP_852664.1	in vivo	7   537   275   864   942   710   000   000
5335	PLCG1	1398	NP_002651.2	in vitro;in vivo	866   085   310   430   888
5781	PTPN11	1470	NP_002825.3	in vitro;in vivo	106   555   847   589   239   000   000   000   000   000
5829	PXN	3937	BAA18998.1	in vitro;in vivo	9   658   172   113   374   900   000   000
6093	ROCK1	3414	NP_005397.1	in vitro	15247219
6401	SELE	566	NP_000441.2	in vitro	8609175
6464	SHC1	2780	NP_001123512.1	in vitro;in vivo	11980671
6772	STAT1	2777	NP_009330.1	in vitro;in vivo	11278462
6850	SYK	2514	NP_003168.2	in vivo	93   422   359   169   439
7094	TLN1	1726	NP_006280.3	in vitro;in vivo	7622520
7157	TP53	1859	NP_000537.3	in vitro;in vivo	15855171
7204	TRIO	3537	NP_009049.2	in vitro;in vivo	12551902
7249	TSC2	1850	NP_000539.2	in vivo	17043358
7414	VCL	1900	NP_054706.1	in vivo	10545505
7430	EZR	475	NP_003370.2	in vitro;in vivo	11468295
8737	RIPK1	4583	NP_003795.2	in vitro;in vivo	15121855
8835	SOCS2	5490	NP_003868.1	yeast 2-hybrid	16189514
9140	ATG12	8496	NP_004698.2	yeast 2-hybrid	16189514
9564	BCAR1	4248	NP_055382.2	in vitro;in vivo;yeast 2-hybrid	1   151   461   774   798   640   000   000   000   000   000   000   000

Pathway Information

                                                                                    

Pathway Name	Pathway ID
Amoebiasis	hsa05146
Axon guidance	hsa04360
Bacterial invasion of epithelial cells	hsa05100
Chemokine signaling pathway	hsa04062
ErbB signaling pathway	hsa04012
Focal adhesion	hsa04510
Leukocyte transendothelial migration	hsa04670
Pathways in cancer	hsa05200
PI3K-Akt signaling pathway	hsa04151
Proteoglycans in cancer	hsa05205
Regulation of actin cytoskeleton	hsa04810
Small cell lung cancer	hsa05222
Transcriptional misregulation in cancer	hsa05202
VEGF signaling pathway	hsa04370

Structure Information

No matching records could be found.

Domain Information

ID	Location	Description
cd05056	415-684	PTKc_FAK
cl21453	415-684	PKc_like superfamily
cd13190	254-364	FERM_C_FAK1
cl17171	254-364	PH-like superfamily
cd14473	143-248	FERM_B-lobe
cl09511	143-248	FERM_B-lobe superfamily
cd00192	426-676	PTKc
cd05060	428-681	PTKc_Syk_like
cd05040	428-677	PTKc_Ack_like
cd05033	422-677	PTKc_EphR
cd05032	415-677	PTKc_InsR_like
cd05068	415-676	PTKc_Frk_like
cd05041	428-676	PTKc_Fes_like
cd05034	426-676	PTKc_Src_like
pfam03623	914-1052	Focal_AT
cl04185	914-1052	Focal_AT superfamily
cd05039	415-679	PTKc_Csk_like
cd05044	428-676	PTKc_c-ros
cd05057	421-680	PTKc_EGFR_like
cd05085	425-678	PTKc_Fer
cd05084	425-676	PTKc_Fes
cd05048	416-678	PTKc_Ror
cd05116	428-676	PTKc_Syk
cd05052	415-679	PTKc_Abl
cd05038	428-680	PTKc_Jak_rpt2
cd05065	422-680	PTKc_EphR_B
cd05066	417-680	PTKc_EphR_A
cd05115	428-693	PTKc_Zap-70
cd05036	416-681	PTKc_ALK_LTK
cd05148	415-679	PTKc_Srm_Brk
cd05059	424-676	PTKc_Tec_like
cd05053	409-680	PTKc_FGFR
cd05063	416-680	PTKc_EphR_A2
cd05067	414-676	PTKc_Lck_Blk
cd05099	409-680	PTKc_FGFR4
cd05061	415-672	PTKc_InsR
cd05072	415-689	PTKc_Lyn
cd05050	416-672	PTKc_Musk
cd13999	428-672	STKc_MAP3K-like
cd05064	416-680	PTKc_EphR_A10
cd05108	426-695	PTKc_EGFR
cd05075	421-682	PTKc_Axl
cd05109	426-679	PTKc_HER2
cd05074	413-680	PTKc_Tyro3
cd05035	424-680	PTKc_TAM
cd05058	426-682	PTKc_Met_Ron
cd05049	416-676	PTKc_Trk
cd05083	420-678	PTKc_Chk
cd05110	413-695	PTKc_HER4
cd14204	414-681	PTKc_Mer
cd05051	416-672	PTKc_DDR
cd05090	423-676	PTKc_Ror1
cd05091	416-678	PTKc_Ror2
cd05082	415-679	PTKc_Csk
cd14203	428-676	PTKc_Src_Fyn_like
cd05055	405-672	PTKc_PDGFR
cd05062	415-672	PTKc_IGF-1R
cd05112	428-677	PTKc_Itk
cd05073	415-676	PTKc_Hck
cd05092	417-676	PTKc_TrkA
cd05045	421-680	PTKc_RET
cd05101	407-680	PTKc_FGFR2
cd05098	409-687	PTKc_FGFR1
cd05071	415-688	PTKc_Src
cd00180	428-676	PKc
cd05100	409-680	PTKc_FGFR3
cd05111	425-677	PTK_HER3
cd05070	415-688	PTKc_Fyn
cd05054	415-677	PTKc_VEGFR
cd05069	415-688	PTKc_Yes
cd05046	428-677	PTK_CCK4
cd05113	417-680	PTKc_Btk_Bmx
cd05043	417-677	PTK_Ryk
cd05114	426-681	PTKc_Tec_Rlk
cd05080	418-681	PTKc_Tyk2_rpt2
cd14205	428-679	PTKc_Jak2_rpt2
cd05093	417-679	PTKc_TrkB
cd05102	415-682	PTKc_VEGFR3
cd05097	416-678	PTKc_DDR_like
cd14207	415-679	PTKc_VEGFR1
cd05079	426-680	PTKc_Jak1_rpt2
cd05094	417-676	PTKc_TrkC
cd05096	416-677	PTKc_DDR1
cd05081	428-676	PTKc_Jak3_rpt2
cd05095	416-676	PTKc_DDR2
cd05103	415-681	PTKc_VEGFR2
cd05047	428-681	PTKc_Tie
cd05089	420-685	PTKc_Tie1
cd06606	421-672	STKc_MAPKKK
cd05106	384-683	PTKc_CSF-1R
cd14014	421-678	STKc_PknB_like
cd05105	405-680	PTKc_PDGFR_alpha
cd14058	428-681	STKc_TAK1
cd14003	423-674	STKc_AMPK-like
cd05088	417-684	PTKc_Tie2
cd14061	428-679	STKc_MLK
cd14145	416-679	STKc_MLK1
cd06627	424-672	STKc_Cdc7_like
cd05122	423-673	PKc_STE
cd05104	405-672	PTKc_Kit
cd05107	405-680	PTKc_PDGFR_beta
cd14059	428-676	STKc_MAP3K12_13
cd14007	423-674	STKc_Aurora
cd08215	414-667	STKc_Nek
cd14206	428-677	PTKc_Aatyk3
cd14060	429-679	STKc_MLTK
cd14147	420-679	STKc_MLK3
cd05037	422-669	PTK_Jak_rpt1
cd14148	428-679	STKc_MLK2
cd14146	428-679	STKc_MLK4
cd05117	423-667	STKc_CAMK
cd14008	428-673	STKc_LKB1_CaMKK
cd13978	428-676	STKc_RIP
cd05042	428-677	PTKc_Aatyk
cd14009	428-672	STKc_ATG1_ULK_like
cd05087	428-677	PTKc_Aatyk1
cd08224	414-667	STKc_Nek6_7
cd06623	422-672	PKc_MAPKK_plant_like
cd06632	425-672	STKc_MEKK1_plant
cd06612	423-672	STKc_MST1_2
cd06609	420-672	STKc_MST3_like
cd14065	428-676	PKc_LIMK_like
cd06626	421-672	STKc_MEKK4
cd14221	428-680	STKc_LIMK1
cd07829	420-667	STKc_CDK_like
cd14062	428-676	STKc_Raf
cd13979	420-667	STKc_Mos
cd14663	421-674	STKc_SnRK3
cd13992	451-679	PK_GC
cd14002	420-672	STKc_STK36
cd14151	414-682	STKc_B-Raf
cd08217	475-672	STKc_Nek2
cd14080	424-681	STKc_TSSK-like
cd05086	428-667	PTKc_Aatyk2
cd14150	428-681	STKc_A-Raf
cd08529	414-672	STKc_FA2-like
cd14025	428-681	STKc_RIP4_like
cd06610	414-672	STKc_OSR1_SPAK
cd14222	428-679	STKc_LIMK2
cd14063	422-673	PK_KSR
cd08225	421-672	STKc_Nek5
cd08228	428-667	STKc_Nek6
cd14099	420-672	STKc_PLK
cd05118	428-667	STKc_CMGC
cd14154	428-679	STKc_LIMK
cd14027	466-671	STKc_RIP1
cd14064	428-678	PKc_TNNI3K
cd14121	427-671	STKc_ULK3
cd14095	423-639	STKc_DCKL
cd14010	451-672	STKc_ULK4
cd06611	428-672	STKc_SLK_like
cd05581	414-667	STKc_PDK1
cd08219	426-675	STKc_Nek3
cd14137	421-667	STKc_GSK3
cd07830	423-667	STKc_MAK_like
cd06628	425-672	STKc_Byr2_like
cd07833	428-672	STKc_CDKL
cd14149	411-679	STKc_C-Raf
cd05123	475-674	STKc_AGC
cd13996	418-667	STKc_EIF2AK
cd14006	428-639	STKc_MLCK-like
cd05077	468-669	PTK_Jak1_rpt1
cd08229	428-670	STKc_Nek7
cd14079	424-623	STKc_AMPK_alpha
cd14072	421-682	STKc_MARK
cd14116	420-667	STKc_Aurora-A
cd05580	422-666	STKc_PKA_like
cd06614	428-672	STKc_PAK
cd14155	460-682	PKc_TESK
cd14161	419-666	STKc_NUAK2
cd14096	420-639	STKc_RCK1-like
cd06640	428-672	STKc_MST4
cd14119	428-673	STKc_LKB1
cd08223	423-667	STKc_Nek4
cd14048	423-672	STKc_EIF2AK3_PERK
cd14070	424-667	STKc_HUNK
cd06625	424-672	STKc_MEKK3_like
cd14202	415-648	STKc_ULK1
cd06642	428-672	STKc_STK25
cd14066	428-672	STKc_IRAK
cd14012	463-672	PK_eIF2AK_GCN2_rpt1
cd06616	422-674	PKc_MKK4
cd14152	421-682	STKc_KSR1
cd06917	421-672	STKc_NAK1_like
cd06641	428-672	STKc_MST3
cd14097	425-639	STKc_STK33
cd06613	414-672	STKc_MAP4K3_like
cd14073	421-666	STKc_NUAK
cd14000	468-677	STKc_LRRK
cd13998	427-679	STKc_TGFbR-like
cd08528	428-678	STKc_Nek10
cd06605	428-672	PKc_MAPKK
cd14084	426-672	STKc_Chk2
cd07841	421-667	STKc_CDK7
cd14208	422-669	PTK_Jak3_rpt1
cd08222	469-672	STKc_Nek11
cd06644	428-672	STKc_STK10
cd05582	426-666	STKc_RSK_N
cd05076	468-669	PTK_Tyk2_rpt1
cd14069	424-674	STKc_Chk1
cd06608	420-674	STKc_myosinIII_N_like
cd05078	431-669	PTK_Jak2_rpt1
cd06643	428-658	STKc_SLK
cd14056	427-667	STKc_TGFbR_I
cd07832	414-666	STKc_CCRK
cd06630	425-672	STKc_MEKK1
cd14071	423-666	STKc_SIK
cd07831	428-667	STKc_MOK
cd06618	475-672	PKc_MKK7
cd06621	422-667	PKc_Pek1_like
cd05579	451-674	STKc_MAST_like
cd06624	414-672	STKc_ASK
cd14187	419-672	STKc_PLK1
cd06620	463-672	PKc_Byr1_like
cd14075	428-673	STKc_NIM1
cd13987	428-624	STKc_SBK1
cd14201	414-655	STKc_ULK2
cd14183	420-625	STKc_DCKL1
cd14185	423-666	STKc_DCKL3
cd08530	461-675	STKc_CNK2-like
cd14105	423-625	STKc_DAPK
cd14074	423-673	STKc_SNRK
cd14156	465-681	PKc_LIMK_like_unk
cd05578	462-666	STKc_Yank1
cd14196	423-635	STKc_DAPK2
cd13997	428-672	PKc_Wee1_like
cd05572	428-666	STKc_cGK
cd14162	422-642	STKc_TSSK4-like
cd08220	465-675	STKc_Nek8
cd06631	425-672	STKc_YSK4
cd14081	423-666	STKc_BRSK1_2
cd07834	421-667	STKc_MAPK
cd14184	420-644	STKc_DCKL2
cd06648	418-672	STKc_PAK_II
cd13991	419-682	STKc_NIK
cd08218	428-667	STKc_Nek1
cd14054	428-617	STKc_BMPR2_AMHR2
cd14164	424-667	STKc_TSSK6-like
cd14068	428-667	STKc_LRRK2
cd13989	428-623	STKc_IKK
cd13993	421-672	STKc_Pat1_like
cd14045	439-679	PK_GC_unk
cd06607	426-672	STKc_TAO
cd06617	423-672	PKc_MKK3_6
cd14047	428-676	STKc_EIF2AK2_PKR
cd14103	428-631	STKc_MLCK
cd14199	466-675	STKc_CaMKK2
cd14120	428-671	STKc_ULK1_2-like
cd14117	423-666	STKc_Aurora-B_like
cd14189	425-624	STKc_PLK3
cd06638	423-672	STKc_myosinIIIA_N
cd07840	415-625	STKc_CDK9_like
cd14076	424-673	STKc_Kin4
cd14190	428-625	STKc_MLCK2
cd06633	428-615	STKc_TAO3
cd14086	428-701	STKc_CaMKII
cd14026	426-680	STKc_RIP2
cd14188	425-672	STKc_PLK2
cd07852	451-671	STKc_MAPK15-like
cd06629	425-673	STKc_Bck1_like
cd14191	428-635	STKc_MLCK1
cd14094	420-671	STKc_CASK
cd14052	428-626	PTKc_Wee1_fungi
cd06639	428-672	STKc_myosinIIIB_N
cd14067	428-667	STKc_LRRK1
cd14042	475-676	PK_GC-A_B
cd14153	421-679	PK_KSR2
cd05611	428-666	STKc_Rim15_like
cd06647	428-672	STKc_PAK_I
cd13990	428-672	STKc_TLK
cd14053	431-671	STKc_ACVR2
cd14165	424-672	STKc_TSSK1_2-like
cd14192	428-637	STKc_MLCK3
cd14077	423-666	STKc_Kin1_2
cd14195	423-635	STKc_DAPK3
cd14194	420-635	STKc_DAPK1
cd08221	426-672	STKc_Nek9
cd14038	428-623	STKc_IKK_beta
cd14158	419-679	STKc_IRAK4
cd07857	421-666	STKc_MPK1
cd05574	469-666	STKc_phototropin_like
cd14098	423-674	STKc_Rad53_Cds1
cd06645	419-615	STKc_MAP4K3
cd14078	420-623	STKc_MELK
cd14193	415-635	STKc_MLCK4
cd13983	465-672	STKc_WNK
cd06634	426-615	STKc_TAO2
cd05570	479-666	STKc_PKC
cd06622	428-672	PKc_PBS2_like
cd14050	428-672	PKc_Myt1
cd14083	419-623	STKc_CaMKI
cd14186	420-624	STKc_PLK4
cd14055	428-673	STKc_TGFbR2_like
cd06656	428-672	STKc_PAK3
cd13982	450-667	STKc_IRE1
cd14043	433-679	PK_GC-2D
cd14091	414-668	STKc_RSK_C
cd13994	428-668	STKc_HAL4_like
cd14200	466-673	STKc_CaMKK1
cd07859	421-700	STKc_TDY_MAPK
cd14144	426-679	STKc_BMPR1
cd14106	463-625	STKc_DRAK
cd14142	420-680	STKc_ACVR1_ALK1
cd14082	428-646	STKc_PKD
cd06654	428-623	STKc_PAK1
cd07862	428-648	STKc_CDK6
cd07860	428-635	STKc_CDK2_3
cd06653	424-672	STKc_MEKK3_like_u1
cd14664	428-637	STK_BAK1_like
cd05583	465-666	STKc_MSK_N
cd14109	465-638	PK_Unc-89_rpt1
cd14118	466-673	STKc_CAMKK
cd07843	428-635	STKc_CDC2L1
cd05612	423-666	STKc_PRKX_like
cd07846	428-672	STKc_CDKL2_3
cd13975	479-681	PKc_Dusty
cd07863	428-635	STKc_CDK4
cd06655	428-672	STKc_PAK2
cd14039	428-666	STKc_IKK_alpha
cd14089	473-672	STKc_MAPKAPK
cd06635	426-615	STKc_TAO1
cd14093	462-666	STKc_PhKG
cd14057	428-669	PK_ILK
cd14131	420-672	PKc_Mps1
cd14132	420-635	STKc_CK2_alpha
cd06646	413-615	STKc_MAP4K5
cd07836	428-635	STKc_Pho85
cd14114	415-630	STKc_Twitchin_like
cd14004	414-672	STKc_PASK
cd06652	424-616	STKc_MEKK2
cd07866	407-625	STKc_BUR1
cd14665	421-673	STKc_SnRK2-3
cd05595	426-666	STKc_PKB_beta
cd06636	423-660	STKc_MAP4K4_6_N
cd05584	480-666	STKc_p70S6K
cd14209	466-679	STKc_PKA
cd13985	426-672	STKc_GAK_like
cd08216	423-624	PK_STRAD
cd06637	423-623	STKc_TNIK
cd07854	451-616	STKc_MAPK4_6
cd14033	428-615	STKc_WNK4
cd06659	465-623	STKc_PAK6
cd14198	423-630	STKc_DRAK2
cd05614	423-666	STKc_MSK2_N
cd14167	419-623	STKc_CaMKI_alpha
cd07861	428-666	STKc_CDK1_euk
cd07838	428-667	STKc_CDK4_6_like
cd05604	426-666	STKc_SGK3
cd07842	427-667	STKc_CDK8_like
cd14159	428-616	STKc_IRAK1
cd05602	426-676	STKc_SGK1
cd05620	426-666	STKc_nPKC_delta
cd07870	428-628	STKc_PFTAIRE2
cd05585	428-666	STKc_YPK1_like
cd07845	424-623	STKc_CDK10
cd05613	423-666	STKc_MSK1_N
cd06619	428-667	PKc_MKK5
cd07835	420-666	STKc_CDK1_CdkB_like
cd14104	423-639	STKc_Titin
cd05619	424-666	STKc_nPKC_theta
cd14113	465-623	STKc_Trio_C
cd13988	428-662	STKc_TBK1
cd05630	426-666	STKc_GRK6
cd14166	419-639	STKc_CaMKI_gamma
cd05610	410-674	STKc_MASTL
cd14011	528-667	PK_SCY1_like
cd05624	413-644	STKc_MRCK_beta
cd06658	428-623	STKc_PAK5
cd14044	451-679	PK_GC-C
cd05616	491-666	STKc_cPKC_beta
cd06657	465-672	STKc_PAK4
cd14110	465-638	STKc_obscurin_rpt2
cd00836	256-351	FERM_C-lobe
cd07839	428-635	STKc_CDK5
cd14092	480-639	STKc_MSK_C
cd05573	420-674	STKc_ROCK_NDR_like
cd07858	427-666	STKc_TEY_MAPK
cd14177	432-639	STKc_RSK4_C
cd14087	428-624	STKc_PSKH1
cd07864	428-648	STKc_CDK12
cd05577	428-675	STKc_GRK
cd14005	423-681	STKc_PIM
cd14133	428-668	PKc_DYRK_like
cd14179	456-624	STKc_MSK1_C
cd06651	425-616	STKc_MEKK3
cd14219	420-683	STKc_BMPR1b
cd14169	423-623	STKc_CaMKI_beta
cd07876	420-630	STKc_JNK2
cd05623	413-644	STKc_MRCK_alpha
cd07873	428-615	STKc_PCTAIRE1
cd14041	420-666	STKc_TLK2
cd07877	428-656	STKc_p38alpha
cd05593	426-666	STKc_PKB_gamma
cd14030	392-615	STKc_WNK1
cd14088	420-623	STKc_CaMK_like
cd06615	463-674	PKc_MEK
cd14143	428-615	STKc_TGFbR1_ACVR1b_ACVR1c
cd07865	428-619	STKc_CDK9
cd14016	421-575	STKc_CK1
cd14178	473-639	STKc_RSK3_C
cd13995	428-672	STKc_MAP3K8
cd07855	420-616	STKc_ERK5
cd07869	428-635	STKc_PFTAIRE1
cd14220	426-679	STKc_BMPR1a
cd05598	498-623	STKc_LATS
cd14049	419-667	STKc_EIF2AK1_HRI
cd05592	480-666	STKc_nPKC_theta_like
cd05607	426-627	STKc_GRK7
cd14170	481-623	STKc_MAPKAPK2
cd05590	426-666	STKc_nPKC_eta
cd07853	422-616	STKc_NLK
cd14111	469-667	STKc_SPEG_rpt2
cd07878	420-635	STKc_p38beta
cd14085	452-623	STKc_CaMKIV
cd07850	470-620	STKc_JNK
cd05615	428-635	STKc_cPKC_alpha
cd14175	428-639	STKc_RSK1_C
cd14040	420-666	STKc_TLK1
cd05571	469-666	STKc_PKB
cd06650	463-657	PKc_MEK1
cd14031	408-615	STKc_WNK3
cd07871	422-615	STKc_PCTAIRE3
cd14172	481-623	STKc_MAPKAPK3
cd07847	420-672	STKc_CDKL1_4
cd05631	524-639	STKc_GRK4
cd05603	426-623	STKc_SGK2
cd07849	420-616	STKc_ERK1_2_like
cd14046	415-568	STKc_EIF2AK4_GCN2_rpt2
cd14180	471-673	STKc_MSK2_C
cd13977	421-616	STKc_PDIK1L
cd14176	400-639	STKc_RSK2_C
cd05594	423-666	STKc_PKB_alpha
cd14019	428-666	STKc_Cdc7
pfam00373	143-248	FERM_M
cd05609	479-639	STKc_MAST
cd05601	423-637	STKc_CRIK
cd07874	470-672	STKc_JNK3
cd07848	421-653	STKc_CDKL5
cd07875	470-669	STKc_JNK1
cd13986	459-672	STKc_16
cd05575	505-666	STKc_SGK
cd14107	415-639	STKc_obscurin_rpt1
cd14210	421-625	PKc_DYRK
cd14032	422-615	STKc_WNK2_like
cd13968	428-566	PKc_like
cd14090	425-625	STKc_Mnk
cd06649	416-615	PKc_MEK2
cd05589	426-642	STKc_PKN
cd05605	524-635	STKc_GRK4_like
cd14108	469-637	STKc_SPEG_rpt1
cd05587	491-729	STKc_cPKC
cd05632	524-639	STKc_GRK5
cd08226	443-667	PK_STRAD_beta
cd07851	475-635	STKc_p38
cd14001	452-616	PKc_TOPK
cd14197	529-625	STKc_DRAK1
cd14181	462-623	STKc_PhKG2
cd07856	451-671	STKc_Sty1_Hog1
cd07880	419-625	STKc_p38gamma
cd14036	421-681	STKc_GAK
cd14212	429-646	PKc_YAK1
cd05622	408-623	STKc_ROCK1
cd07872	428-615	STKc_PCTAIRE2
cd14101	529-672	STKc_PIM2
cd14163	423-672	STKc_TSSK3-like
cd07879	428-625	STKc_p38delta
cd14135	428-632	STKc_PRP4
cd14168	419-623	STKc_CaMKI_delta
cd14662	421-673	STKc_SnRK2
cd14115	428-623	STKc_Kalirin_C
cd14141	480-615	STKc_ACVR2a
cd05618	479-630	STKc_aPKC_iota
cd14017	428-656	STKc_TTBK
cd14100	423-672	STKc_PIM1
cd05617	491-674	STKc_aPKC_zeta
cd05591	480-712	STKc_nPKC_epsilon
cd14140	431-616	STKc_ACVR2b
cd05597	526-648	STKc_DMPK_like
cd14125	421-581	STKc_CK1_delta_epsilon
cd14020	442-666	STKc_KIS
cd05608	491-669	STKc_GRK1
cd08227	459-624	PK_STRAD_alpha
cd13183	270-350	FERM_C_FRMPD1_FRMPD3_FRMPD4
pfam07714	422-676	Pkinase_Tyr
smart00295	36-258	B41
smart00219	422-676	TyrKc
smart00221	422-676	STYKc
smart00220	423-674	S_TKc
pfam00069	422-673	Pkinase
COG0515	423-741	SPS1
PTZ00267	446-716	PTZ00267
PLN00034	420-672	PLN00034
PTZ00263	404-623	PTZ00263
PHA02988	400-678	PHA02988
PTZ00283	529-681	PTZ00283
PTZ00036	374-700	PTZ00036
PTZ00426	408-623	PTZ00426
PTZ00024	422-652	PTZ00024
PHA03209	469-616	PHA03209
PHA03212	454-615	PHA03212
PHA03211	470-623	PHA03211
PTZ00266	409-643	PTZ00266
PRK13184	420-681	pknD
PHA03390	475-630	pk1
PLN00009	418-569	PLN00009
TIGR03903	450-654	TOMM_kin_cyc

Ontology Information

   

HPRD ID	2164
Molecular Class	Tyrosine kinase
Molecular Function	Protein serine/threonine kinase activity (GO:0004674)
Biological Process	Cell communication (GO:0007154); Signal transduction (GO:0007165)

SNP Information

View SNP Geneview Report