Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| RALB | 5899 | V-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein)  | 2 | -  |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 21715253    | 2011 | Cell line : - Source : Gene Ontology database Sample Type : - No. of Sample : - Stage : - | Soft agar colony size and formation frequency,Immunoblotting. | Unknown | - | - |
| 18006783    | 2007 | Cell line : - Source : - Sample Type : - No. of Sample : - Stage : - | Cluster and pathway analyses were done using GeneSpring software and Gene Ontology database. | Up-regulation | - | Clusters of expression showed different expression in the transformed cells that revert to normal after treatment; they included Ras/Erk/Ral-B, Jagged2/Notch, calcineurin, lysyl-oxidase. Cluster and pathway analyses were done using GeneSpring software and Gene Ontology database. |
| 22790202    | 2012 | Cell line : - Source : ATCC Sample Type : - No. of Sample : - Stage : - | real time RT-PCR and western blotting, immunohistochemistry | Up-regulation | - | - |
Gene Details

| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | This gene encodes a GTP-binding protein that belongs to the small GTPase superfamily and Ras family of proteins. GTP-binding proteins mediate the transmembrane signaling initiated by the occupancy of certain cell surface receptors. [provided by RefSeq, Jul 2008]   | Chromosome | 2 |
| Location | 2q14.2 |
| Start | 120240070   |
| End | 120294711   |
| Strand | +   |
| Gene Sequence |    Download   Select all |
| Length | 54642   |
| OMIM ID | 179551    |
| HGNC ID | HGNC:9840    |
| Unigene ID | Hs.469820     |
| Ensembl ID | ENSG00000144118    |
| PharmGKB ID | -    |
mRNA Information
| mRNA ID | XM_005263724.1 |
|---|---|
| Exon | join(1..56,38549..38709,45805..46013,49511..49688, 53072..54642)   | mRNA Sequence |    Download   Select all |
| Length | 2275   |
CDS Information
| Location | join(38..56,38546..38709,45805..46013,49511..49688, 53072..53191) |
|---|---|
| CDS Sequence |    Download   Select all |
| CCDS ID | - |    
Protein Information
| Protein ID | NP_002872.1 |
|---|---|
| Protein Name | V-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein) |
| Molecular Wt. (Da) | 23277 |
| Protein Sequence |    Download   Select all |
| Length | 206   |
| Uniprot ID | P21291 |    
| Ensembl Protein ID | ENSP00000345079   |    
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
| EC | 3.6.5.2 |    
|---|---|
| Name | small monomeric GTPase |
| Class | Hydrolases; Acting on acid anhydrides; Acting on GTP to facilitate cellular and subcellular movement |
| Sysname | GTP phosphohydrolase (cell-regulating)   |
| Substrate | GTP [CPD:C00044]; H2O   |
| Product | GDP [CPD:C00035]; phosphate   |
| Reaction (IUBMB) | ![]() |
PPi Information
(Click to view network : Source STRING)      View   
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 801 |    CALM1 |    241 |    NP_008819.1 |    in vitro;in vivo;yeast 2-hybrid |    12034722    |
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Pancreatic cancer |    hsa05212 |    
| Pathways in cancer |    hsa05200 |    
| Phospholipase D signaling pathway |    hsa04072 |    
| Rap1 signaling pathway |    hsa04015 |    
| Ras signaling pathway |    hsa04014 |    
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd04139 | 15-178  | RalA_RalB |
| cl21455 | 15-178  | P-loop_NTPase superfamily |
| smart00173 | 15-177  | RAS |
| smart00010 | 15-177  | small_GTPase |
| cd00876 | 16-176  | Ras |
| cd04138 | 15-177  | H_N_K_Ras_like |
| cd04145 | 15-177  | M_R_Ras_like |
| cd04177 | 15-177  | RSR1 |
| cd04144 | 16-180  | Ras2 |
| cd04175 | 15-176  | Rap1 |
| cd04136 | 15-176  | Rap_like |
| cd04176 | 15-176  | Rap2 |
| cd04141 | 15-181  | Rit_Rin_Ric |
| cd00154 | 16-172  | Rab |
| smart00175 | 16-176  | RAB |
| cd04137 | 16-176  | RheB |
| cd04146 | 16-177  | RERG_RasL11_like |
| cd01868 | 14-176  | Rab11_like |
| cd04123 | 16-176  | Rab21 |
| cd01867 | 13-179  | Rab8_Rab10_Rab13_like |
| cd04143 | 15-172  | Rhes_like |
| cd04148 | 16-185  | RGK |
| cd01860 | 16-176  | Rab5_related |
| cd04147 | 16-177  | Ras_dva |
| cd01869 | 14-179  | Rab1_Ypt1 |
| cd01861 | 15-169  | Rab6 |
| cd01866 | 14-179  | Rab2 |
| cd04140 | 15-173  | ARHI_like |
| cd01862 | 16-174  | Rab7 |
| cd01863 | 16-176  | Rab18 |
| cd04119 | 15-176  | RJL |
| cd01864 | 14-176  | Rab19 |
| cd00157 | 16-174  | Rho |
| smart00174 | 17-169  | RHO |
| cd04113 | 16-176  | Rab4 |
| cd04111 | 16-179  | Rab39 |
| cd04120 | 16-181  | Rab12 |
| cd04122 | 16-176  | Rab14 |
| cd04116 | 8-176  | Rab9 |
| cd04110 | 14-204  | Rab35 |
| cd04127 | 14-167  | Rab27A |
| cd00882 | 20-174  | Ras_like_GTPase |
| cd01865 | 14-169  | Rab3 |
| cd04117 | 16-179  | Rab15 |
| cd04114 | 14-176  | Rab30 |
| cd04106 | 16-169  | Rab23_like |
| cd04112 | 15-179  | Rab26 |
| cd04130 | 16-169  | Wrch_1 |
| cd04109 | 16-183  | Rab28 |
| cd04142 | 16-182  | RRP22 |
| cd04115 | 16-173  | Rab33B_Rab33A |
| cd04132 | 16-169  | Rho4_like |
| cd04107 | 16-204  | Rab32_Rab38 |
| cd00877 | 16-174  | Ran |
| cd01871 | 16-176  | Rac1_like |
| cd04129 | 16-169  | Rho2 |
| cd01870 | 16-169  | RhoA_like |
| cd01874 | 16-169  | Cdc42 |
| cd04133 | 16-169  | Rop_like |
| cd04135 | 16-169  | Tc10 |
| cd01875 | 16-176  | RhoG |
| cd04118 | 16-169  | Rab24 |
| cd04101 | 16-174  | RabL4 |
| cd04121 | 14-174  | Rab40 |
| cd04124 | 16-175  | RabL2 |
| pfam08477 | 16-131  | Miro |
| cd04131 | 16-169  | Rnd |
| cd01893 | 16-170  | Miro1 |
| cd04108 | 15-170  | Rab36_Rab34 |
| cd04134 | 16-174  | Rho3 |
| cd04126 | 16-204  | Rab20 |
| cd09914 | 16-167  | RocCOR |
| cd04172 | 16-164  | Rnd3_RhoE_Rho8 |
| cd04174 | 9-161  | Rnd1_Rho6 |
| cd04173 | 16-185  | Rnd2_Rho7 |
| cd04103 | 16-176  | Centaurin_gamma |
| cd04128 | 16-172  | Spg1 |
| cd04159 | 19-168  | Arl10_like |
| COG2229 | 16-173  | Srp102 |
| cd04153 | 15-153  | Arl5_Arl8 |
| cd00878 | 16-169  | Arf_Arl |
| cd01873 | 16-174  | RhoBTB |
| cd00880 | 20-169  | Era_like |
| cd04152 | 13-142  | Arl4_Arl7 |
| cd01887 | 116-167  | IF2_eIF5B |
| cd04160 | 68-139  | Arfrp1 |
| cd01854 | 114-168  | YjeQ_EngC |
| smart00177 | 16-134  | ARF |
| cd01897 | 90-168  | NOG |
| cd01895 | 103-169  | EngA2 |
| cd01892 | 19-139  | Miro2 |
| pfam00025 | 16-134  | Arf |
| pfam07826 | 34-131  | IMP_cyclohyd |
| cl01330 | 34-131  | IMP_cyclohyd superfamily |
| cd04156 | 16-146  | ARLTS1 |
| cd04164 | 90-167  | trmE |
| pfam00071 | 16-177  | Ras |
| PTZ00369 | 15-177  | PTZ00369 |
| COG1100 | 16-186  | Gem1 |
| PLN03118 | 6-176  | PLN03118 |
| PLN03108 | 14-179  | PLN03108 |
| PLN03110 | 14-176  | PLN03110 |
| TIGR00231 | 16-169  | small_GTP |
| PTZ00132 | 16-176  | PTZ00132 |
| PLN03071 | 16-176  | PLN03071 |
| PTZ00099 | 35-169  | PTZ00099 |
| smart00176 | 20-176  | RAN |
| COG1160 | 16-182  | Der |
| COG1162 | 90-168  | RsgA |
| COG0486 | 15-167  | MnmE |
| PRK00093 | 103-182  | PRK00093 |
| TIGR03918 | 89-168  | GTP_HydF |
| PRK12298 | 122-186  | obgE |
| TIGR00450 | 15-132  | mnmE_trmE_thdF |
| COG1159 | 90-184  | Era |
| PRK05291 | 55-179  | trmE |
| PRK00098 | 114-168  | PRK00098 |
| TIGR03594 | 103-169  | GTPase_EngA |
Ontology Information
| HPRD ID | 412 |    
|---|---|
| Molecular Class | Unknown |
| Molecular Function | Extracellular matrix structural constituent (GO:0005201) |
| Biological Process | Cell growth and/or maintenance (GO:0008151)   |
Drug Information
No matching records could be found.
External Links
| ArrayExpress | GO |    
|---|---|
| ICGC | GO |    
| Cancer3D | GO |    
| COSMIC | GO |    
| NCG | GO |    
| TSGene | GO |    
| Tumor Gene Family of Databases | GO |    
| CCDB | GO |    
| G2SBC | GO |    
| Osteosarcoma Database | GO |    
| RCDB | GO |    

