CoReCG

Search results:

General Information

Gene_Symbol	Gene_ID	Gene_Name	Chromosome	Alias
SPARCL1	8404	SPARC-like 1 (hevin)	4	MAST9

Evidence
Gene
mRNA
CDS
Protein
PTM
Enzyme
PPi
Pathway
Structural
Domain
Ontology
SNP
Drug
External Links

Evidence Information

Pubmed ID	Year	Sample Information	Techniques	Mechanism	Fold Change	Remark
21887554	2011	Cell line : - Source : Departments of Pathology from Linkping University Hospital, Linkping, and Vrinnevi Hospital, Norrkping, Sweden Sample Type : - No. of Sample : normal colorectal mucosa and primary and lymph node metastatic tumors from 164 patients with primary colorectal adenocarcinomas Stage : TNM Stage I-IV	Immunohistochemistry	Up-regulation	-	Expression of SPARCL1 protein might be a valuable biomarker for early diagnosis in colorectal cancers and further predicting patients' prognosis. SPARCL1 was negative in the distant normal colorectal mucosa, weakly expressed in the adjacent normal mucosa, strongly expressed in primary colorectal adenocarcinomas and slightly expressed in their lymph node metastases.

Gene Details

Chromosome 4 - NC_000004.12 (87473330..87529503, complement)
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Gene Type	protein coding
Gene Family	EF-hand domain containing
Description	-
Chromosome	4
Location	4q22-q25
Start	87473330
End	87529503
Strand	-
Gene Sequence	>gi\|568815594:c87529503-87473330 Homo sapiens chromosome 4, GRCh38.p2 Primary Assembly AAAAATGCATAAAGAGCCAAGTGCTTATATTCTGGCCAAGTTATGAGGCTCTGAGAACAAGAGCTTGAGG GGAAGACTGTTAACCCCATCCACGCCACCAGAATTAGCTCTTTCCCTTTTGGTTTGCAAGCACTGCCTGT AAAGCCCTCGCATGAGAGGCCAGCCTGCTAGGGAAATCCAGGAATCTGCAACAAAAACGATGACAGTCTG AAATACTCTCTGGTGCCAACCTCCAAATTCTCGTCTGTCACTTCAGACCCCCACTAGTTGACAGAGCAGC AGAATTTCAACTCCAGTAGACTTGAATATGCCTCTGGGCAAAGAAGCAGAGCTAACGAGGAAAGGGATTT AAAGAGTTTTTCTTGGGTGTTTGTCAAACTTTTATTCCCTGTCTGTGTGCAGAGGGGATTCAACTTCAAT TTTTCTGCAGTGGCTCTGGGTCCAGCCCCTTACTTAAAGGTAAGTTGTAATAAATTTACGGCATTATCTA ATTGCATTTGTTAAGCTGATTTGCGTGATCTGATAAAGCTGTCAAATATTTTTGCCTAAATAATACAAAG CCATTTATTTACCAAAAAAAGTTTTGTGTGATTTACAGAAAAGATACTTCATAGAGAATTTTACCATTTG TATTCATGTTTTCTTGTTTCCTGCGAAATTAAATAGCAAGTACTAATAAATGATGGTGATTTTAGTGAAG ACCAAGAATAGAAATGTGGAACTGTTGATCGCCTCAGTAGCATTCAGATCTTAGTGAAGCCTGAATCCTG AAATGTGTTTTGTAGAAGTACTTTATTACATATATGAAATAAACTATAAAGAAGGTAGTTTTTAAAAAAA ATTTCAAATCAAATAATTTGTATGTTTTCCATGTTTAAATTATCTAAAGTTATTCAATCTCCTGAGCCTA ACAGCAATGTAGAAACGGAACTTTTTGCTTTTCCAAAAGGTAGGAAAATTTCTCCTTTTATACTATATTC TTGTTTGATTATTTTTAAGTTATTGCGATTATTTTCCCTTTCTTGGTTCCCTTTTACAGCTTTATAACTA ATTATTTTTTGCCTCCTACTATCATTTGTTAAGATGCTCACACATAGACCTAAAATTTCTCTAATTCTTG ATAATGTCTTATTTACAAAAGCAAAAATGGGAGAAGAGAATTAAAGAGCTAAAGAGATTATGGTAACTCA TATTATAATGTACTACCATTTCTGGCTCTCTTTTCTAAAATAAAGCAATAATGTAGGTTGTGCTTATTCA TCCTTCCCAGGTATTAAAGGTCACTCTGCAAGAGAAAAAAAGAAAAGAAAGGAAAAGAAAAGAAAAAAAA ACATGCTTTTAACTGCAGATCAATACTGTTGAAACAGTACACCAAGAGGTACTGCAGAAAGAGTATCTCT TTTGCACTGCCTTTAATCTGCAAAGAGGTTAAATATGTCACCTTGGCATTGTATCTGAGCTCTCCTCTGG CCCAGGGCCTAAGCACATTGAATAGAAATGTTCACTCAGTCCAAGTCAGCAGAAATCTTTTTTTTTTTTA TTCTCCCCTTTCTCGTAGACACCAGCTTTTTTCAGTTCACAGCTTACTCAGTCAAACCTGATGGTTGTGA CTATTGTTAACTATGATTTTTTTTTTATTCAAAACACCCTCTTTGGAAAGATTTAAGTTAATATTTCTGT TCATTTAATAAGATCTAGCAAAGCAGAGCAGTTTATTTCATCTACTTATCGTCCAATCAACTAGTGCCAC TTTCCACATTTTGGAGAAGAATATTCACATGTTATTTATGAACCTTGCCTTTTTCTTTCAGAGAATTTTT CACACAGCCATTGAGCAATTAGAGTGCTGGCATTTCCTTCCTAGGTCTTTTGAGATTTAATCCCCAGTAG CTCCTCATGGCACAGATTCACATATCAACTAAGTAAAAATAATAGTGATGACAGAAATAAAATGAATAGT GATGCATCTGGACAACTTGAAAACATTATTTATTTCATTTCCTCTTGACTGTTCTTTTTACTCAGTTGAC TTAAACACTGCTATTTTACTTAAGTTTAGCACCATATCCAGAACTGGTTGGGAACATTTTTCTACCGAGA AGGGCATAAACAACTTGTTAGAAGATCTGAAGTGCACATAGTCCTCACTTATCCCTCTAGAATGATCTTC AGTGGAGAAGGAGACCCCCATAAATAAATCCAGTAGAACTTCCCAGTAGGCCTGGCTTCCTGAGAGATGT CCAACCAGGCCAGGGTCTGTTTCTTACGGGGCTCACAGGGCATCTTCTGCCAAAGGCTGAGTTAGCGATG ATAGCATTACCTAGGGCTAGCCTGGCTTTTGTCTTAGTCATCAAAAGATGGATAGAACTTTGAAAAACAG AGTGCATGGTCTTGATGATTGTTCCAAAGGTGGGGAGGCAATCTAATAAAGTGAATAAGGCCATGACCTG TGGTTTATATCTGACCATATGGACCCTGTTTATATAAGACCGTGGTTTATATCCAAGCTTTACCACAAAA TAGCTCTGTGACTTTGGGCAAACAACTTCATCTCTTTGTGCCTCAGTCTCTTCATTCATGGAAATGGGAT TATAAAATCAGTAGCTACCTCAGAGATTTGTTGTAAGAATTAAGTGAAGAAAAGAGCCATGTTTGGTACA TTAAAGCAATCAATCAATCGTAGATAATATGAAAGTACTGGACTAACTATATGTCCCTATTGAAACTCCG TAGAACGGGAACTGACTCTAGATATTTTCTCAGGGTTTCTTCCTTGTACTTATACGTTTTGCTCTATAAT AAAATATGAATGCCAGGTGTATGCCTCTGAGGCAGCACAGCAGAGTGGACAGAGCATGGGCTTCAGAGTC CAATGCATCTGGGCTAGAATCCTGACTCTGCTTCTTACAATCAGTGTAAGCTTTGGCAGTTACTTCCCAC CTGCATGACTCAGTTTACTCATCTGTTTAGCAAAATGGGGATAATAATACACACAAATGAGGTCGTTGTA GGAATGAAATGTGATGTTTATTAAATGCCAAGTATAGCACCTGGCAGAGAAGTAAACACATAGGAAAGTT GACTGGTTGCTCATAAGGAATCTCGTATATCAGTGAGGCCTCTGTTACATACTTGCAATGATTTCTCTGG TAGTAACAATGGAGATCAAGAAGGAAATATTCTTTGAATTGCCTTTTTTATCCAAAGAAATGTAAAAGTA AATCGGACACTACTATTTTCCCCTGGTGGGGGGCCTCAACACGAGGTATTTATTACTATGAGACTTCACT GCTGCATCAGTTAGTAGCTTCTTAATGGCCAAGTCAAAGGAAACCAAAGAAAGTGTTCTATGCCAGCTTG CCATTACACAGAGTGAGAAGAAATGCTGCTTTGCTGTCAATTCTGTTTTATTGGCCCACTTGGACAAGAG GGAAAGCCCCCAACATTTCTTCTTTCTTATCTCTTCTAAAGGCAAGAATAGGGCTTTTGACTTGCTCCAG GGGATATTTTTTCCTCTCTAACTGAAATTCAAGTGAAAGAGTCTTTTTTTTGTTTTTTTGTCTTTGTTTG GTGTTTTTGTAAACCTCTCCCCTATGTTCCTAGCATTGAAATGTAAGCTGCTTTTTCTGGCTGCATGTAG CAGGAGCAGGCTGTCGTCATAGCAATGAAAGGGTGTAGAGAGACTCCTGCTTCATGACCTGCTCTGGGAA ATAACTCTTAGTCTGCTTTAAAATCCTTCTTTAGAAATGAAGTCTCCAGTCCTGGCTTGTTTCCTTCCTA TTACACAACCAACTTATGTACACCCATTGCAGTAGCTAAATGTTTCCTTTAAAGATTTAGTGAATAGGTA TTTTAAAAATCAACAAGAGAGCTGCTAAAACAGTGGCTAGTTTACTGTGGCATACAGGGGAAAAACAACT GGGAAGGCAAAGAAAGAGAAATAGAAATGGCCTCACATGATACACATACTGCAGCAAACCCTGCAATAAA TCCATTTTTCAAGTTCCCACTGCTTCCTCCCATCTTCACGATGTGCTATGGTGTAGTGGTTATAGAGGGG AATTCTGGGGCAGACTGCCTGGACTTGAATCCTGGCACTCATACCTTCTAGTTGTTTTAATCTAATCCAT TCTGTGCCTCTGTCTTCTCATCTGTGAAATAGATATAATAACAGTCATAAAATTGTCATGGGAATTGAAT GAGATTGAGCATGTAAGGCATTTATTACAGTATCTAACCCATGGTAAAGGTTGGCTGCTAAGCTCAGGAG CCTCAGTTTCCCCCACTTGTGAAATGTGGATAACAGCTAATTCATAAGATCATTGTATTTTTTTTTTTTT TGAGACAGAGTCTTGCTCTATTGCCCAGGCTAGAGTGCAGTGACATGACCTCAGCTCACTGCAACCTCCA CCACCTGAGTTCAAGTGATTCTTGTGCCTCAGCCTCCTGAGTAGCTGGGACTACAGGCATGTACTACCAT GCCTGGCTGATTTTTGTTGTTTTAGTAGAGATGGGGTTTTGTCATGTTGGCCAGGCTGGTCTCAAACTCC AGGCCTCAAGTGATCTGCTTGCCTCAGGCTCCCAAGGTGCTGGGATTACAGGTGTGAGCCACCATGCCAA GATGATCATTGTATGATTAACTAAAATAATGAATGTACATGCTCAATAAGTAGTAGTTATTACAATTCTT TTTCATGGTTTTGTTATTGAAACAGCAAGGTTCCAGTCTAGGTCCTGCTGCTCACTTCGTAGAAAGCCAA TCACTGAGACAACAAGTATTGCCAATGAAGAAGGCTTTAATCAGGTGCTGCAGCTGAGGAGATGGGAGCA CAGTCTCAAATCCATCTCACTAACTGACTTAAACTAGGGGTTTACATAGCAAGGGAAAAATGTAACAATG TGTAAGAAAATAAGAACTAGGTAGGGGTAAGGAAACAATCATGGTGAATAAGCGGTCAGGCATCTGCTGC AGTGATCTGGTGAGTTTCCATTCTTTTATACTTTTTTAGAAGCCTGAAGGTCCTGTCCTGAGGAAGGAAC TTAGATAAAACAAATATAAGTTTCACACTTTAAGACCAGGAGGGTCAACTTCTATGTTTTTCAAAAAGAT CTGTCTGTGGGACTATTGGGTAAGTTTCAGTTTGATCTAACTCTGACATGAATGGCCTTTTTGAACTTAG AATTCCCAGTGAGTCAAATATAATGAATAGAGGCCTCAGAATTATCATTGCATAAATGTGAACCATTTGA TTTCTACAGGGGGAAAAAAAAGAATTGTGACTTTTTACATTTATAAAGACTCATCTCATCTTGATTAACA CCAGGGTAAAAAGTATTAAAACATCTTATCTTTCATTAACTTTTTATTACGTTTCTGTTTCAGTTCCTCC AGTGTTTTCTAGGTCATGCAATTATGAAAATAAGTTAGCATTTTTATCTTACATCTCAAACAACTAATGT ATTCAGTGTTCTATCCCATGCAAAATTCCAGAAATGCAGCAAGGAGCAAAACTAGAGAGGGGCTGAGCTC TTGTGGTGCTTACTATGTAGTTATGAAAATGGTCATTAATCAAACCATCACAATAATGAAAACTGCATAG GACCAAACATAAGGTGCCCCCAAATACAATGCCATCTTCATCTTTCTAGTGAGAACATCCTCAACCAAAG TGTTTGGCCAAACAGCATGTACAAATGGGTAATATATTGTAATGTACACTTGGGATATTTAATCTATGGT TCACATACATATTTAATATGTTACTTTAATTTAAATATTTTATACTTATTAACATGACTTTTTCCTTTCT CACATTTCATGAAACAATTTTGTTAAAACTCTTCATACGCATCTTTAACACCAATGTGTATGTTCACTGG ATCCACGCTGTAATTATCTAATACAGAGCACATCATCAATCCTTCTGCAAGTTGCTAAACATCTGCTGAT GCTGCAAATTTAATCCCCAGGCATTAGTCCTCACTCGTGGTCATGTTCTCCACACTTTCATTACTGACTA GATTGTTTTTCCAGTGCTTTTTAAAGGGCGTATTTAAAAACCACTTGAAACTGTAAGTGTGGCTTTCTAA AACTATGTGATTCCAACTTGCAATAATGAAGTCATACCTCAGGAATAATGACTAAACCTGCTTTAAATAT CTTTATCTATTTTTTCATCCATTTTGTCAAGGTGACCTTCCTAAGAATAAAAATAAGCATTGCTTGAGAT TTTTTTTTTTTTTGAGACAGAGTCTCATTCTGTCACCCAGGCTGGAGTGCAGTGGTGTGACCTTGGGTCC CTGCAACCTCTACCTCCTGGGCTGGAGCAATTCTTCTGCCTCAGCCTCCTGAGTGGCTAGGATTACAGGT GTGCACCACCACGCCTGGCTAATTTTTTGTACTTTTAGTAGAGACAGGGTTTTGCCATGTTGGCTAGGCT GGTCTTGAACTCCTGACCTCAGGTGATCACCCACCTCGGCCTCCCAGAGTGCTGGGATTACAGGCATGAG CCACTGTGCCCAGCTCTTGAGATGATTTCTAATTGTTTTTTTGAATAGTACTTTGCTGCTCAAAATGAAG AAACTTTGGAAGCACTTGAATATAAGTCAAATCCCTCTTTTTTACGGCAGGATTTGGTGGCGTGAGAAAA AACACATTTTATTTGAACACATGCCATATATAATGATACACTGAAATAAGTGTTATGAAGGCAAAACACC TTTGTTCCAAGAGAGTATATAAGGATCCTGACCTCCACTCAGGATCAATAATGGCTTTCCTTGATCTGAA GTCTGAATAGAGGTTAACTCTGTGTGTGTGCGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTG TGTTTGGTGGTGGTGGCTGGGAGGAGCGGGTGCTGGAGAGAGAATTCTGACAGCGTGAACACTTGTGCAA AGACCCTGGAGCAAGAGGGATCGTGGCCTATTTGAGGCACTGAGAGGCAGCCAGCTCCCGAGAGCAAGGG CAGAGCAGTGGAAGATGTAAATCTCCATAATACTCCCTTCCCTGAGCACTAAATGTATGTGCCCTTTGCT TGATTCAGGTTTAATGTATACTTTTAACGTCTGGATGGATTTCTGGTTAGTCTCAAAGCCCCAACAGGCA TGACCATGTCTATCCCTAGCTCAGACTCTTATGGTGGTAGGTTCAATTAGGAAGGATGATGGGCAGTTGA AGGTCAGATGCCCAGAAAAGTCTTAAGTCATTGACTCTGAGTATATCATATACACTCACAGGGCTGGGAC ACCTTGATGTCAGATGGTGACTCAGCAGAGAACTCAAAATAGAAGAACGTCTTTTTCACCCTTCAGATGA CTTTAGGGCCAAACCATAGAGCTCTCCCCAGAGACTCATTAATACTTTAAAAGCTCTAAAGCATCAGTGT TAACACTGGATCAGGTAACAGCACGTATATGTTAGCCAAAATATGACTAAGAGATTTGCTCTCTGATAAC AAGGCCTTTGACTATTATGTAAAAACAAGGTGAACAGGAACGTTCTGAGTCTGTTTATAAAGTACCTATA ATAATTGTTTTGTTTACTACATTTCCCAGAAAGGAAATTTTTCCATAGTTGTAATAATTGCTAAAAATAG CAGTCTACAGGCTTCCTCTGATATAAACAAATTCAACAGAAGATACCTGGCCTTATTTGGATGCATGGAT GTACATACTCCAGGAAATGATAGGCCAAGAGTAATAAGAAAAAGAAAGTAACAAGACAAACCTCTCCTTT TTCTAGTACACATGGTATGTCTTTCTTAGTTCATTAAACTTTAGACAAAGTGATAAACAGATCAAGTTGT CATCATCTGCCTTGAAACCCAAAAATATTGAAACAAGTTCCCTAGGCCCAGAAGGGAAGGAAGAGGACTT GTAAATTTTGCTGAGGCTGCCACAGAAGGAGCTAACCACTGGAGGGTTCAGACTGGAGGGTTCAGAAACC AGGGGAATGCTAGGCAACACAAGGAAAATTCAATTAGAAAGACTTGAAGCAATAACTACCAGCACTAAAA TTTCCAGGGAGTCACTGATGTGGCCAATATGAAAGAGGAATCCTGTTCCTCCTTTCAGAGGTATGGATGA CTGCGTTTACAGTCTGGTTCAGTGTTCAGACAGCTTATTAATGCTTAAGAGAAAAGGAAAGAGAAGGAAG ATAGAAAGAAGAAGTACAGCAAGGCAAGAAGTGCCCAGGGGAGCAGGTGTGCTAAGTTGATTTAAGTGGC ATGGCAATATACAGAACTTCAAAAATAAAATTTATCTTTTAAAATTTAAATGTAAATTAATGTTCTAAAA AACTATAGGAACTGAAAATAAATCAAATACAAATATCTACTTCGACCTAATCTTACTGTAATTTAAGTTT CTAGGAAATATCATAGAAACTGAAGTGGAACCAATTACAGAAAAAGAATGCAAAATAAACCATAGTACCG AAAATAAAAACATATTCTGGTCGTTTGTGTAGGTTCCCTAATAAATCTAGACGGAGAATGATGTTTTTGT GTTTTAGTGTATGCCAAACTTTAGACACCCTCCTCTTTTCTAGGAGATACAAATTTCAGGAGCGATATTT AGCTATTACACACATAGCTTTTCATCAGAGATGGGGGTAGCTGACACACACATGGCCCATTCTGCCCATA CCTTTCAGGTCAATCTCTGATGGCTTGGCTGGGCTGTTTCCAGCTAGCAGAAAGGATATTCAGGCCCCTT TTCCTTGCTTTTCCAGGGACAGAGCTTGTAGAGTGCTGAGAAATCCAATTACAACTTCCTTTCATGGTGA AATCCAATTACAACCTCTCCCATGGTGAAAGCCAATCTTTTTGATACAAAAGGAAACTAAACAAAAGGGC TTCAGGCAGGGGATATGCTTGTGCTCTGCCTTCTCACTTTGACAATTATGCAGGAAGGTTGCAATGACCT TGGCTTGCCTTGCTTAGGAACAAAAGTCATAATCTTCTACCCCCTACTCCCACAAAAAGGAAAAACGTTT TCATATCTGATTCCAGGAGTTTGGGGAGTTTCCTCAAGGATCCATTAGTCAGGCAAAGCAAATTTTGAGC CAACACTTGCTCCCTCCCACACACTTTTTTTTCCGGCAAGATGACTTTTCTTATTGAACTTGGAATGCCA TGTTAAATGATAAATAAATTAGTGAATTATTTAGGCCAATATCCTCCCATAATCTGTTCCCAACAACTTT TTTTTTTTTTTTTTTTTGAGACAGTGTCTGGCTCTGTCACCCAGGCTAGAGTACAGTGTGCAGTGGTGCA ATCTCGGCTCACTGCAACCTCCGCCTACCCAGCTCAAGTGATTCTCCTGCCTCAGCCTCCTGAGTAGCTG GGACTACAGGCACCTGTCACCACGCCTGGCTAGTTTTTGTATTTTTAGTAGAGATGAGGTTTCACCATGT TGGCTGGGCTGGTCTTGAACTTCTGGCCTCAAGTGATCCACCCACCTCGGCCTCCCAAAGTGCTGGGATT ACAGGTGTGAGCCACCGTGCCTGGCCTGTTTCTGCTACCTTTGTGATATCCAATGCTGTGTGTCACCCTT TCAGCCAACCTGTTTGCTTGAGGTTAGTGAGACTGTAGTACTGCTTGGAGAGGGGTCATCCTAAATTCCT AAAACCTGGTTGAGATAAACGGAAACAGTTCTCAAAACAGTAATTTATGAAAATAGATATTTTATGAGTA CTTGACACAAGTCTATAATTGCTGAGATATTTAAAAATAAAATTACTAACCACATTCTATTCAAATCTCT GTCACTTCTGTATAATCACTGTACTCCACTGAATGTGTGTAAAATATGTATTTGCAGCTTATAGGGAAAA AAATTTGCAAATTTTCAGAAGAATCATGCAGTCAACTAATAGGTTCTTAGTTGAAGATTAGTGGAGTGGG GAGTGGTAAATGGTTATCTTTTTCAAAACTTAGGACAAACTTTACACTAGGTTCAAATAAAAGTGCTATG GCTACAGAGTTAATGAACCCACCATTCAAAGTGGCCCTAAATAGCTCTGAAAGCAAAGCATTTTTACATT ATTTGATTCAACTTGAGTTATCTAATTGCCTATATAATATGATAGGGACCCAGGCCGGACACAATGGCTC ATGCCTGTAATCCCAGCACTTTGGGAGGCTGAGTCAGGTGGATCACTTGAGGTCAGGAGTTCAAGACCAG CCTGACCAACATGGTGAAAACCCGTCTCTACTAAAAAATATAAAAATTAGCCGGGCGTGGTTGTGTGCAC CTGTAGTCTCAGCTACTCAGGAGGTTGAGGCAGAAGAATTGCTTGAACCCGGGAGGCGGAGGTTGCAGTG AGTAGAGATCAGCCACTGTACTCCAGCCTGGGCAACAGAGCAAGACTCCATCTCAGAAAAAAAAAAAAAG ATAGGGACTTGATAGGAAGGTACCCTGAGATATACAAAAATCAGAAGAATTGACCTTTATGATAGGTAAA TAAAACATGTAAATGGTTTCATGACGTGTTTGGTCAGATGTTCATGCTGTCTTAGCTCATTGAAATCATT TTTAACTTTCAAGCCATTAGTTCAGTGGATCCTCCCAACCTTTTACTGGGGACCAAACAATTTTGAGCTA ATTCTCTCTAAATCAAGGGAGTATTCTATTAGAATTCAGAAGAAACAAAGCACAAATTCTTAACCCTAAG TGTCTTCTTTTTCTCTCTTTTTCTTCCCTGTTGCCCAACTCCAGCTAATGGGTTTTAAGGACTTTATAAT GAGAAGCAGGTTAATGTCTTACTAGAAAAACTTTTCAATAATTTCCTAAAATATGGGGAGAAGAAAATAG TGGAAGATGTTGTTATAAAATAGAAAAATGCTTGGTTGAAACCTTGGTACTCGTATTGATCTTGTACTCA TTAGCTTTTTGGATAGGCATAGGCGGGGAAGAGAAGTATCAGCATCATCTCACTGATAAAAACAGCTGAT GTCTTCTTACAGTCTGAAAATGAAGCCATTGATTTCAAAAGCAAATGTTTTATTATACTTTGAAAAACAC TCTGGATTGGATCATTCAAGGTTATGATAGCCTGAGATAACTGCAGCCTCAAACTCCCGGGCTCAAGCAA TCCTCCTGCCTCAGCCTCCTCAGTAGCTGGGACTACAGGCACGAGCCATTAAGCCTGGCTTGAGGGGAAA AGTCTTTTCCCATGGTGGGAGGAGAAGAATTAACAGCTGTGGACCAGCTGTGGGCAAGCTGTGTCTTTTC CTTGCTTGAAGGCATCTTCTTAACATTTTCTCTCTGAAGGCATAAATAAGCTTCCAGGTTTTCACCCTAT TTTCAAAGAACTTTTCAAACTCTAGCCTTAAAATCCATTAGGGTTTATTACATCTGCTTCTTTCAGAAAA GGTAGATAATAAGTAACTTTGCACCACTGAGGTAAGCAAGCAATTGTTTCCCATATTAAATGTGTTGGCC CTCACCAAGGTACATGAGAAGCTTGGACCACGATCTGAATCCTAAAGGGACTTCTGCTGGGACTGAATGC TTGCATTAGCGGTTCACACAAGAACTAAATGCTCATCAAAGTACACCATTATTCCCCAGAAGGTCCCAAC ACCATGAGAATGAGGCTACTTGGAACTGTTCTTTGGTATTATTTGTTGTTTTTCTTAATCCTAGAAGAGA ACTACCCCCCAATAAATAATTCTTGGTCCATTCACAGAGCTGAAAGCACTTGAAATTCCTCTCCCAACTA GCAGAATTTAACAACTGACTTACTCTGTTAGCAAAAGAGAGGCAATTTCCACTGAATCCAAAGGAGTTTT ATATTATACTGGTAGAGTTTAACTAATAAGGGAAATTCAAATAAGAGCAGTCAGAGGATAAAGCCAAGAA CTAGGCATTCAGGGGAAAGAAATTACAGGGGTAGTAGAGAAACAAATAAATTAAGGGGTAGGGAGAAGAG TTAAAGGCAGAAAAAGCAGAGGATTAATCTATCTGATAATTACAGGGGCTAGGCTTTAAAAGGTGTATTG TCTTACTATTAACAACATGAAGCCAATCATTCAGATATTATTAAGTTACTGCAACGTCACAAACGCCAGG ACTTTAGGTGAGCCATCCTAAGAGCAGATTCAGGGTTTGTGAAGCCAAGAGTTTATACATATGTTTGGAA CCTTCTTTTTTAAAAATATAAAAGTCAAAATCAAGTCTAGAACTTTGTATGGAGGCTGCACAAGTGAGGG GCCTTGAAACTCAAGCTTCCTAGTTTTATGGCACGTCTATCCTGGCCATATTCAAATGTCTATACCCCAA ATACAACAAAAAGTTCAGAAAAATAAATAAATGTAAATATGAGAAAATCCTGTGTTCTCTTTCTCTGAGA AAGAGAAAATAGTAGCACAGATACCATAGTAGGACTTGAGCAAAGAAAAATAAATATGGCCAAAATAATG TCTCCCACTATAACACAGGACAGGGTGTGGTGGACCCTTTCTGAAGGATTGGCAAATGTCTGAGAAAAAG AACAGGCAACTGTCTCCCTGGATGGATCCATCCCATCTGGAGCTCTGGAATGAGACACAGTGAGATTAGT GAGTGGTATGATAAGACGAGAAACTCTGAAAGGCATGATTAAGAGATGGTGAAAGGTGGCTATTGCACAA GCTTGGGTAAGATAAGCCTGGGGGATCCTCTAAATATAATTAAAGTAATCCCTCAATTACACATTATAGA AAAGGAGGAATGGACTAGTTTCGCCTGAGCAAGAAAGAAACAGACCTTTAAGAATGTGTCTGAAAAGCTG TGCCTCCGGGTGCCCTTTGGCTTCCATGCTCCTCACTGCTGACCAGGCACAGTGGCAAAGAGGGATGGTC AGGAAGCACTCACTGAATGGTAGTTCTGTGAAATGGAGGTGAGGGTCACAGATGGGAGTGCATGGATGGT ACACAGGTGAAGTGCTTAGCATAGAACCTGGCATATAGTAAAATCTCAGGAATGTATATGCCATTGAATG AGCTACTATTAAATGGTCTAAGACAAAAATGTACTTTTTCAATAAAATAATACTTTGATGACCATAAGTG ATTCTACTACTGAGTACATTTGAGTGCTATTCCACACAAAAATATTTAATGTTTACAGCCAATTATATAT GGCTTCTTACAAACTCAGTGACTCAAAGCAACTGTTTCATAATGTCTCGAGATCTGGTGGGTCAGAAATT TGGGCAGGCCTCTCAGAGGTACTCAGCTAGGAGATGAGCTGATCTGGAGTGGCACAGGATCTCTCCACTC ACGTGTCCTGCGCATTTGCAAGGACAGATGCAAAGCTGGGATTGGTAGAACTGTTGAAGTGTCTTCTGTG ACATGACAGACTCAGAAAATGGCTCAAGGCTCCCAAAATGAGTTTTCCAGGAGATTAGGTAAAAGTTCCA AGGTTTCTTATGACCTAGCCTCAGAAGTCCCAGAACATCATTTCTATCTCAATCAATTGGCCAAGTAAGT CACTAAACCCAGTCCAGATTCAAGGGAAGGAGAATTAGACTCCACCTCTCAACAGGAGAAATAGCAAAGA ATTTATAGCAATCTCTACCATAATATTTATACCTATTAAATAAGAAATGTAAGAAATTGTCTCAAGGCAG TTACTCATGTGAGTTAGAATAGAGTTGACATTTGTGGGTGTTTGGCTCTTAATGGGAGACCTATTTCTGC CATGACAAATGATTCCTCTGGAGATTTGTTTTAATGGTACATGGGTCAGCCAATAGAAAAACTCTAGGCA TTTGAAATTCAAATGCTGGATGTTCTCTATAAAATGCTGTCTAGCTATCATCTTTTAAAATTCCAGCTGA GGTTCTCCTGAAAGTTTGGTAATGAGACACCCTGTTCCTAACAGAAGGAAAGGGCTCTCCTTCCAGTTAC CTATCATCCCTCATCTTTAACCTCTCTAAATCCATAAAAAGAAACAGTGGGATGAAGAAAAGAAAGAAAT AACCTAAGGACTCTAGTAAAGGGATGAATTAAAGTGTCTGAATTATTCATTATTGGGGTTATTAAGCCAT TTTCTGCCTTATGCATGTTTCAAAGATATGATAACATCTTTCATTTCATTTTTACAGTTGGTGAAATTAC CAAATAACTATAGGATCACATTTGAATCTCAAAACAACTCCAGAAGATAGATAAGAAAATGTAATATTAC CTTTCCTGTTTTGTAGATGAAGAAACCAGTGACTTGATCAAAGTCTCTTAGCTGGTAAAAGGCAGTTCAA GTCTGGAACTTAGATCTTCCAGTTCCGTACCAACTGTCCTTTAAACTATGCAGCTGCCTTTGAATAAGCT CACGCATTTGAGCAAAATAATATTGATTTAGTTTCACATCAATACTGCATATTTAAGTCTTTGAGAATAA TAATTCTGTGAATTCCAAAATTTGTCTCATTTTTGCATTTTTCATCTGGAGTTTTATTTTCTATTTCTGC AAAAATAATCTGTATTTTGTAGTCAGTGCACACCAAACTCGAATGTCTCAAAATAAATGACTTTTTACTC ATCCAAGAATAAATGGTATTCATCATACTTAGCAAGGACATCATGGTTTTGATTTTTCAAAGTACTTTGC AAGCATCAGCTAATTAAGCCTCCCTGAGTCTTCAGTATGACAGTTGTTTTCAAAATATCTCTCATTTCCC AGGAAAGTTCTCCATTCTGTCTTATTTATACAATCAGCACATTTGCTCAGTTCTTAAAATAAGAAGCTAA AGGCCATGAAATTATTTTTGATCAATATGTGGCAAATACAATTAGCTCAGTGAGACAAAAATGCCCAGTG ACTAGTCTAAAGGACAACGTGGAACACAATGGAAGAACACAAGGCGTTTTAAAGTCTAGATACTGGATTG TCCCACAAGGTCCTTCAAAAATAAAACACAGGCATCTTCTTTATAATTGAAACTTGAAGGGGTTTCCTGC TTGGATCATTCTAAATGACATGACCATACTCTGCGTTTAAATTTTGTTTTCAATTACAGGATGGAAAAAA ACTCTTAAAAAATAGTTCCATCTTTGGACTCAGTAAAAATCAGGGACCATTCAGTAAATGTTGGCTCTCA AAAAGCCTGCACAAGTGGCCATCTGAGGTTATATGACAATCCCTAGACTTGTTCTATGCCTTAAAATATC TTCCATACAGCTACGCCAGGATTCTCAGCATTCGATAGCTCTTTTTGGGTTAAGAACAATGTGAACATAC CTCTTACCTGAGAATAGAAATACATTAATTCAGGAATAATCTTTTTTCTTTTTTTTGAGATGGAGTCTCA CTCTATTGCTGGAGTGCAGTGGCTCAATCTTGGCTCACTGCAACCTCCACCTCCTGGGTTCAAGAAATTC TCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGCTCATGCCACCACGCCCAGCTAGTTTTTGTGTTT TCAGTAGAGACGGGGTTTCACCATGTTGGACAGGCTGGTCTCGAACTCCTGACCTCAAGTGATCTGCCTG CCTCAGCCTCCCAAAGTGGTGGGATTACAGGCATGAGCCACAATGCCCAGCCCTAATTCAGGAATATTCC TATTTCCTCGGTATGGTTTAGATGCATGCAAAAAACAAAGATTTAAAAGTATAGAATATAGGATAGGTGA GTTTGTGTTTAATGAGTGAACTAAAAGTAAATATGTTCTGGAACTAGCTCCTGGGAAGCTTGAAATCCCC TAGGGGAGGAAGATACGGAAAAGGGGAGGAGAAACACTAAGGTTCTTTTCCCTTATATCACACTTAATAC AAGACATATGTAGTTAATACAAGATATAAATGACTCTAATGATATTACTGATGACAGGCAGCAGGCAGAA CAATGAAAATAATAATCATTTGCATGTGTAAGGTACTTCAGAGTTTGCAAAGAGCTTCCTCACCTCACCT TGCAAGGAGCTACCTTTGACATCGGAAGGAACTGGTATTCCCATCCTATATATGAAGTTTGGAGAGAGAA AGTAATTTGTTCAAGGTAGTATTTAGTACTTGGCAAAGCCAGGGCCCAAAGCCAGAACTTCTGGCTTCTA GTCTGTAGCCTGTTCACTAGTCTGTTTGGGGAGAATATTGGATACTGAGTCCAAAGCTCAGCGTTTCTAA TTCTTGCCCACCTCTTAAGCCTTGTACATTTGGCCAAATAATTTAGACTCTTCAAATTTCTGTTTCTTTA CATTTAAAAATTCTGTCCCTCCTTTCTTCATTGAATCAAATGAGACAGTATATAAGAAAACACTTTATAA ACTGTGAAATGCTAAATAAATACAAGGAATGTATAACTAAATCCATCTTAATAAGTTAATATTCCTTGGA ACCCTGCCTCAAGACATCCTTACAGTTAAACTTTCCTCCCTTTTGTGTTAAAGAATAAAGAGTTCCTCCT TCTCTTTGGAGTTAAACCTTTCACATGTGCTTTAATAGTAGACCAGTAAATATGTATCCAGGATTTACCA AGATGGTATTGTCTCACTTAATCTTCATACTATTTTATAGACAATGAGCTGAAGCCCCCAAAAGCTACAC AATTTGCTTATTTACGCAAATTAAGTATTACAGCCTATGACATCCTGTTTCAGAACTTATGCCTTTAATT GTTATGAAATATTGTCTTGCTAATGGTTTTGGCAACTGGTCTGTTTTGCCTTATTTTGGTTTTCGGTTGC TGTAAAACAGTATGCTCTCACATTAAATGGCTTAAAATCACATCCCTGTATTTGCTCATAATTCTCCAAT CTGGATTGGGCTCCACTGCATGATTCTTCTGCTGATTTTGTCTGGAGTTAATTCATCTGGCTTCAGTGAG CTAGGAACACATCTGGGGCTGAATCATCCAGGAGGGTCTGTTATCCTGCAAGGTTCCAGCCACATGGTCT CTCATCATTCAATAGTCTGGGTCAAGCTTTTGTACAGCATGGCTGATAGCTTCCACCAAGAGGAAAAACT CCAATGTGCAAAGGTTTACCAAGTTTCTGCTGGCATCATGCTTGCTAATGTCACATTGGTCAAAGCAAAT CACAAGGTTAAGGCCCACATCATAGGGAAATGAAGCCCAGAAGTTGTGGTTTACTGGGGGTCATCATTGT TTACCATTATCTCCTCTCTTACCCTTTATCTTCAATTTTTCCTTATTTACCTGTCTTTTCCCTTCAGCAC AGAAGGGAAATCTGGGGCCGGGCATGGTGGCTCATGCCTGTAATCCCAGTACTTCCAGGGGGCTGAGGCA GGTGGATCACCTGAGGTCAGGAGTTTGAGACCAGCCTGACCAACATGGTGAAACCCCCATCTCTACTAAA AATACAAAAAAATTAGCTGGGTTTGGTGGCGCATGCCTATAATCCCAGCTACTCAGGAGGCTGAGGCACG AGAATTGCTTGAACCCTGGAGGTGGAGGTTGCAGTGAGCCTAGATCACGCCACTGCACTCCAGCCTGGAA AACAGAGTGAGACTCTGTCTCAAAAAAAAAAAAAAAGAGAAAGAAAGAGGAAAGGAAAGGAAAGGAATCT GAATGATCACATTCAAATACAAATATAAATTTCCTGTAACTGCATATTCCCTTTAAGCTACCACGTTACT CTCCTTTGCACAGCCAATCATTTTTAGAGTGGTCTACACTCACTGCCCTCACTTCATCACTGCCTGTTCA TTCTCCAATCACTGCAGGCTGGCATCCACCGACACCACAGCAACAAAACTGCTCTCCCTGAGATCCTCAA TAACCTCTGCACTTCCAGAGGCAATGGATAATTTCCTGACCTTGTTTGCTTTGAACTCTCTGTGACATTT AACACTTCCCTTTTCTCATGTGACTCTTCTTTCTCTCACTGTTTGTATCTTTAGCTCTTCCCATCCTCTG ATGGTGCCTAATGATCTTCACTCCCCAGGGTTCTGGCTCCAGCTCTCTGCTCAACTGGTTGAATAACTGC TCATGCTACAGCATGCAAGCTACATCTGTAACCCCAAACTCCATGCTTACCTCCAGACCTATCTACCCAA GTATCTACTAGATATCTCTACTCAAATTCAACAAGCCCAAAACTAATCCACCGTCTGTCTTCTAAAACCA AACCTTCCTCCTATAATCCTTCACCTTGGTAATTAATACCACCATTTACTAAGTTGTTCATATGAGAAAT GTGACTCAAGACTTTTCCTTCTCATATTCCTACAATATCTAATTCGTCATTAAGTTTTATCTGTTCTTTT TTTAATTATTTCTTAGAACTATCCAGTTGTGTTTTGGTAAATGAGCAACCCATTCTCTGAGAGAGGGAGA GGTGGGTGACACTTGATGGTTTTCATGGTGTGACTGATCCTCCCACCACAACTGATTTTGATGCAGGATA TTTTCTTGACCCCTTCACGGAACTCGCGGCAGGGGTGCCTTGTTTACTCAGCCCGCCCTGCTCAATCCCT TGCAGGAGGGAGTGCGCAAGCGAATGACTGCAGGAACCTGAGCGAGCGAAGGCAGGAACTGGCCACTTTG GCACCAGCAGGAGCAAACTCCATGTGGGCCCCTCACCAGCGTCCAGGTGTGGGCACCAGCCACGCCAAGC CCCAGAGGGCGTGTAACCATACTCTTAGCTCCACCGTCCGCAGACAGCAGTGTGTTATCAGCTCAGTGAG CCCTTTGCCTCATCACGTAGGGCAACTGCCTTCCGCCAGCAAGGGCAAAGGGCCAGTGCGACCGCCTTTT TGGATACCTGCACGTAGTGTGTCCGAGTTCTTGTCCAGTGCCCAAGAGGAATGAGGTCACACAGATGAAT TGAAGGATGGCGAATGTGGAGAATTTTTTTTTTCAGTGACGAAAGCGGCTCTCAGTGGAGAGGTGAGCTG GAAAGGGAATGGGAAGGGAAGATCCCTCTCCTCTGAAGTCAAGCCACCTCTCTCCTATGTCCAGGCGCTT CTTCTCGACATCAGGCTGCTTCTTCCCTCTGCTGGCTGAGTTCTGGGGTCTTTATGGGCACAGGATGGGG ACGGGGCAGGCCGTAGGTAGTTTTGGAAAAGGCAATATTCAATTGGTAAAAAGACAGTATTCAGAAATAA CCAATCGGGAGAGAATGGAAGTTCTCACTTTGGGCTGTGGGTTTCAGGCTTTTCGGCTTGAAGGTGGGAT TTTGCCAGCGACCCGCCCCTGTATGCCTACAGTTTCTCTGCCTCCTGTTGCTATCAATTTTAAGCTACCA ACATGACGCCACTGAACAGAATCGGGAAGAGACATGCGGAACACATATTATATAGTATTTCCACCAACAG ATATAATAGATGTAAATAACCTCAAAAGAGTAGATAATAGTAAAATAATTATGAAGTGATGAGTTTCTAC TATTTTCTTTGCTTTTAACATAATTAAATTATACATGTATGTAATTTAATTTTTAATTGATGACTTTAAC AACCAACTCAAAAAAGTCTTGAAATGTAACAAACAGCTCTCACAAACCAGTACAGGTTGGATCTATCCCT CTTTTCTCCACTCCTAAGACCACAGCCCAAATGTAAGGCTCTGACCACCTCACCTTGATGTTACAATTGT CTCTCACAGGTCATGCTACTGGTCTGTCCTCCACACAGCTGTCACACATACAAATCTGGTTATATCATCA CCCCTGTCCACACATGTGTGCACACACACAGACATACACACATGCGTGCACACACAGACACTTACAATAA TTCTTTGGGTCCCTATAGCTCTATGGCTGGAATTTTTAATTCCTTGTTTAATGCACTATGACTTTTACAA TATGGCTATCTGCTTACTTTTGAGCCTTATCTACCCCAGCCCACTTCCCCTATTGACAGCCTAGAGACCC AAATATTAACATCCTAGAGACTCGATGCTTCTGCAACTTCACCCATGCTGCTGCCTGCCACCCTCTAGAG TACATCTAGCTGTGTGAGAACATCCTTCATACAGCTAACTACTGTTTATTAGTTTTCAAACCTCAGATCA AGAATTACCTTCTCTGGAGGTCATCTCTATACAGTAGTTAAGAACACTGTAGTTAAGAACACAGACAGAC CTGATATCAAACAGAAGTGTTAAATATCTGCTGTGCCACTTCCTAGCTGTGTAACCCTGAACAAGTTACT TAATCTTTATGCCCGAGTTTCCTTACTAGTGAAATGATTACAATAATGTGCTTACCTGATAGAACTGTTC AGAAGGTTTAAAGAATATGTGTGTGCAAAGCTCTTAGAATAGTGCCTAGAACTTAAGTACTTTGGATGTA GTAAAGTTAGCTATTATCAACTACCTAATTTAAAAATGCCTCCTATCTCTCTTTCCATTGCATTATGTAC ATAATCATCACATTACACTATATGATTTTATATAAATATATTATATATTTATAGATACATTATTAGTATA TACATATATAGATACGTGTATATAATACATATATAGATACATGTATATAAGTATATAGATTATATATGTA CACATATAGTATACATTTAGCCCTCAACCTGTGGGATCTGACACTATCTCCAGGTGCACATACATAGTAT ATACACATATGTATACTATATATATATATATATACTTATATACATGTATCTATATATGTATATATTTATC TATATACGTATCTACATTACATACATATATGTATCTATACACACACACACACACACACACACACACACAC ATATGTTTCATCCACGGTTCCTGTCTCATAATTCCCATAGACCTTTTTATAATGTTATAATGTTGGTGCA TTTTAGGCCTCATAAGCGGACCTCAGAATAACAGGATTTCTCTCTCTCTAATCTTCTATTTTTTTACCTG CTACTTTTTCTCCCCAAGGCAGGACTCTAATCTTCCTCTGCCTTTACCTACCTTGTGTGATTGTAGGTCA TAAGACCCCCATTTCAGAAGGGGTTCTGCCCCATATTCTGGAGGAAGGAATGTTGCATGGAGAGGCCAAG AAGAGGCCCAGCACAGTGATCCATGTCTGTAATCTCAGCACTTTTGGAGGCCAAGATGGGACAATCGTTT GAGCCCAGGAGTTCAAGACCATCCTGGGCAACATAGGAAGATCCTGTCTCTACAGAAAAAAAAAAAATTA ATTACCCAAGTGTGGTGGCAATCACCTGTAACCTCAACTACTTGGGAGGTTGAGGTGGGAGCATGCTTGG GCCCAGGAGGTCAAAATCACGCCACTGCACTCCAGCCTCACAGTCAGAGTGAGACCCACCTCAAAGGAAA AAAAAAAGAGGCCAAAAAGAATCTGAACAGATGGGCCTTACCGGGTTTCCCCACTCAGCCTTTGAGTACT AAAGCATACCCTTTTTGTCTAAACACATTTCTATGTGGTTGTCAATGGTGCCTATCCTTTCATGAAGTCT CCATAAAAGGCCCAAGGGGACGAGGTTTGAAGAAATTACAAGATAACTGAACCTATGGAGGTTCCTAGAG GGTGTGTTCCGGGGAGGGCTTGGCAGCTCTGTGCCCCTTCCCCCATACCTCACCCTTTGCATCTCTTCAC TTGTATCTTTTTGTAATATCCTTTATTATAAACCAGTAAATCTAAGTAGGTGTTTCCCTGAGTTCTGTGA TGCACTCTAGCAAATTAATCGAACCCCAAGAGGGAGTCATGGAAGCCCAACTTGAAACCAGTCAGCCAGA AGTTCTGGAGGCCTGATCTTGTGACTGGTATCTGGGAAAGGGAAGATGTCTTGTGAGACTGAGCCCTCAA CCTATGGGATCTGACGCTATCTCCAGGTACACAGTGTCAGAATTCATTTGGAGGACACTCAGCTGGTGCC TGCTGCAGAGTTGATTGCTTGCATGTTGATGACAAAAAATCTCCCACATTTGGTCACAGAAGTCTTCTGT GTTGATTGTAGCGTGGTGTGAGACCACAGGAAAAGCAGTTAGAGATTTTCCACACCCAGAAACTCTTAAG AGAGAAACTATGTGTCCTTGTGCTTAGGCAGTGTCTAGTAAGTACTCAATGAATGAATTTAAAAAAAATG GATTAGTGATGCAAGTTCTGGCCAACTGGACATTCTTTCCTTTTGATTCATTCAGCTACATTTAGATTTA GGGAAATGAAGGGAACTTGTGAGATCATGTGAGATCATGCGGACAGATTAAAAGGGAAATATTTTCTCAA ATTTAATTAGTTATGCATGTTGCTGCAACAAACAAAAAGAAATGAGCCTTATGATGCAAAACACGTTTGA TAATTCTTACTCCCCTTTTAAGTTGTACCATTTGTAAGAAAATAGGGTAGCATTCCATGTGCCTAATTCC ACTGTTATGTGTGATGAATGTCGGAAATACTCCTGGCATTAAAAGGAGCCTAAATGTGTGGCCAGAATGG ACTTTAATGTTCCACTGGACAATTTTTCTGACCTCACAGCAAAACTTAAATTACATTATTTTCTGAGAAT CTAAGTTGTTTATTCAAGAATCACAACTTAACTTATCAGGAAGATGAGAGAAAAAAGAATTAAAATTTAT TGAGCATCTCCTAGGTATCAGGCATTTTTACCAGTACCATTTCTTCTAACTCTCACAAAACTGAATTAGA TGTTTTATTAGTCAAGGTTCTCCAGAGAAACAGAACAAATAGGAGATAGGTAGGTAGGTAGGTAGGTAGA TAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATGATAGATAGATAGAGATATAGATAATGAG GACTTAGTTTACATTAATGGAGCCAGTCCCAAGATCTGCAGTCAGCAAATTGGAAAGCCAAGAGAGCCAA TTGTATAGTTCCCGTTCAAGTCTGAAGACCTGAGAACCAATGATGTTGAGTTCTAGTCCAAGTCTGAAGG CCTAAGAATTGGAGGGCTGATGGTGTTAAGTCCCAATCCAACAGCAGAATATCAATGTCCCAACTCAAAC AGATAGGCAGAGAGAGAGAGGGAATTCTCCCTTCCCCTGCCTTTTTGTTCTATTCAGGTCCCCAGTGGAT TGAATTATGCCCACTCACATTGGGTAGAGCAATCTGCTTTATTCTGTCTACCAATTCAAATGTTAATTTC TTCAGAACACACCCTCAGAGACACACCCAGGAATAATGTCTAAGTAGATATCTGGGCATCCCATGGTCTA GTCAAGTTGACATATAAAATTAACCATCACAGATGTTATCCCCATTTTTAGATGGGGAATCTGAGGCTTA GAGGGCTAAGTAACTTGCCAAAGATCATATAGATGGCAAATGTTGCTCCAGAGTTCAAATGCATGTCTCT CTAATCTGAAAGCACCAGTCTGCTTCCGCTAAACCAATGGTTCTCAATCAGGGCGATTTTGCCCCCCATG GAACATTTGGCAATGTCTGGAGACATTTTTGTTTGTCCCTAGCTGGTGGGGGATGGGGGCTCGCTACTGA CATCTAATGGGCAGAGGACAGGAATGCTGCTAAGCATCCTACAAGGCACAGGACAGCCCCCCACAACAAA GAATCATCAAGCCAAAATGTTAACAGTGCCAAGATAAAGAAACCCTTCACTAAACCATACTATTTTGTAT TTCTATAGTTTTCAAAACCAGTAGAATAGTAATAACATACTGATCTAAAATATAAGGCTAGGCACAGTGG CTCATCCCTGTAATCCCAGTACTTTAGGAGGCTGAGGTAGGAGGAATGCTTGAAGCCAGAAGTTTGAGAC CAGCCTGGGCAACATGGAAAGACCCCATCTCTACAAAAAAAAAAAAAAACAATTAGCTGAGCATAATAGT TTGCACCTATATCCCCAGCTACTTGAGAGTCTGAGGCAGGAGGATCACCTGAGCCCAGGAACTGGAGGCT GCAGTGAGCTATGATTGCAATTACACTCCAGCCTGAGCAACAGAGCAAGACCCTGTCTCAAAAATAAAAA TAAATAAATAAAATAAAATATAAGTGACTATAGTTCCATAACTCTAATAAATATTTGTGGAATAAATGAA TAAATAAGTAAACATTGAATTTAAAATGTAGAGGAAAGAAACTGCGTTTTTCAATGATTCTTTACAATTA GCATTCACTAGGAGGATAGAATGTTTTAAATTATCATCGCTAATAGAGTCCACATATTTACTTTAAGCAT GAATTACCATATATAAAATATTTTATTTTAATACAATAAAAATCATGGAATATATTTTAGTGGGTTTAGT AGTTTAAGGGGAAAAGATAGCAGCAATTTAGGATTCATACAATTAATGGAATTATTTTCAATTTTAGAAT CCTAAAATATTAGGGTTAGAGGATCATCTAGGTCTCACTCTTCATTGTTCATCACTTGAGAAAACTGTAT CTAAGAAAGGGCAAGTGACTTTCCCAAGGTCTCCTGGCAGTCAGGGACACTGCTAGAGCCAGAATCCAGC TCTCCTGACAGTTTAATGCTTTTCTTGTTTTAAGGTGTTTTTCAATGTATTAGAGTTTTGGGGCAGCGGG GGGAGGTTGCTCCATGTTTTTACTTAAATACATTTTTCTTTCATGGAAAATTGAATTCCTATGCTTTTTG CCTTGTTTAGGCCATAAGATGTTTTATTGAAAGAAACTTTCAATATCAAGTAATCCAACCAACCTTCTAA GATAAGCCTTTTCCTTCAACACAAAGAAGTGCATTTTGCCAAGTACGTACCATCTTACTCCTTAAAATGT TTGGAACTTTTTGTTTAAAAACTCAAACTCAAAGTGAAATCTCAATTTGTCACAATGGTGGTTTTTTTGT TTGTTTTGGGATTTTTTTAGTTTTTGTCCCCCTTCCTTACACCTTTGTGTAAGAGGTAAAATGGAGAATT TGCAAAATAACTAGAAAAAAGCTGGAGTGGGAGCCAGGAAATCTAGCTTCAATCCCAGCTCCCCTTCTAC AGAGCTCAGTGATCTCCAGCATGTCACACTGTAGGCTTTCTAGGCCTGTTCTTCATCTGCCACATCCTGG GGTTGTTGTAAAGATCAAATAAGGTAATATCCCATTTGTAAATTTATTTGGTAAACCCAAAGCACTATGG CAATAGAAATGTCAAGTATATTTTATATGCCATTACCCGTTCTAAATAAAGTAAACACCCATTCCATTGT TAATATTCTAAATTTCTCCTTGTTATATGTAGTCATTTTCAGAAGGATCACTTAGAAGAATTATACTTGA GTCTCCAAGTACATGTCCTTTTCATTAAAACTGGGAATTGATTAGTCCAGACTAGTAAGGTTATAAATGA TTTAAGTTTCTCCCCACACCCCTGATTCAACCCTCCCACCCCCACCCCACCACACACACACACACACACA CACACACACACACACACACACACACACAATACCAAATCACTTTCTATGTGCAGCTTTACTCTCTATTCTT CCAACTGACTGTTCCCTGGTCCAGGTGGCCCACCCTGGACCACCTGGATTTGAATAGTGAGATAGGTAAA AATGTGTTCTTGTTCCCAATATGATGAGGAAGTCTATGCTATAGCCCTGTTTTCTTCAATAAAAACTTCA TTTGCTGCTAGTTTGAGAGGCCGAGGCAGGTGGACCAGTTGAGGCCAGGAGTTCGAGACCAGCCTGGGCA ACATGGCGAAACCCCTGTCTCTACTAAAAATACAAAAATTAGCCAGGCATGGTGGCACATGTCTGTTATT CCAGCTACTTGGGAGGCTGAGGCATGAGAATCACTTGAGCCTAGGAGGCAGAGGTTATAGTGAACCAAGA TTGCGCCATTGCACTCCAGCCTGGGCAACAGAGCAAGACTCTGTATTAAAAAAAAAAAAAGGAAAAAAAA AAACTTCATTTGCTGAGTTAGAACCAAAGACCCACAAAGACCCACAGGAATTCCTATGTGTCACACTAAA AATGATGATGATAATGACAGAGGAAAATATGAAGAAAATATGAAATGGAAGTCATCTGTTGTGAAATGGA GATGAAACATATACATATGTTGCCACTCCCTGCTAAAATTCCAGAATAATGATAGGAAAAGAATAGTAAT AATATAGACTCACAGTGACTGAGATAAAAGAAGAGGAGACAAAGAAGACAAGTGTCAACACATCTTTAGA AGATGGAAGACTGACTTAGAACAGGGAAAGCTTAAACCTAAGAGTCTGCAGAGAAGGATGCCATAGACAA AGAAGGAAGCCATTCACACTGAAGAACCCATGCAAGTTTCCAGAATTGGAGGCACCAGGTGATTTGGAAG GCAGGGTGAGGATAGAGGCTGAAATCTGGAGTATTGGTTGAAAGCCTATCAGATTAACTCTTAGATTCAA GATCCTTCCTCCTGCCTGCACAGCCAGGGGACTTCCATGTTTCAACACAAACAGGAAAAAGCTTATTCTC TGGCTCTGCACTCAGAATAAACACAATGTCAGGTGGGAGGTGGAGCCATACAGAAACCTAGGGACTAAGT GAAAAATCAGTGTGTGCACTGAGAGAACTCCAGTCTCTTCACTGATTTCACAGAATGCTAGCAACCAGGT TTATATTTGCTTCTCAAGGTAAGAGGTATGAATTTCTCCTCTAGAGAAAAGAAAATCTCCCTGTAATATC TGTCAATGACATTTGGGGTGCCCCATCAAGACTGTCAGGTTACTGCTCCTTGGAAGCCCTCCAATGCTCC ATGGAACTATTCTTTGGAAGCCCTCCAAGCCCTGTCCATAAAGTTCTAATTGGCTTTCTAGTGACTCACT GCAAAGTATTAATGGACAGCCAAATACATCAGACATTAGAGAAAAGCTTTCAACAGGAAAAACAAAGATC AAAACAAACTAACTGGGGAAAAAAGGAACAAGAAGGAAACAGAAACTGCAGGGTGCAGAGGAAATTTTCA AAATATTTGATTAATATCCTCAAGGAGACAAGAACATATGTCACACTAATAAAGAACAGGACAATATTAA AAAGAAGCCTTCGGGAAATAAAAAATTAACAGTATATAAGCATATTCTCACTCATATGGAAGCGAAAAAG TTGATCTCATAGAAGTAAGAAGTAGAACAGAGGATACTTGAGGCTGGGAAGGGTGAGGAGAAGAAAGGAA TAGGGAGCTATTTGTTAAAGGACGTAAAACTATAGCTAATAGGAAGAATAAGTTCTAGTGCTCTATACCA CTGTAGGATATTATATATTTCAAATAGCTAGAAAGAAGACACTGTTCCCAATACAAAGAAATAATAACTG TTTGAGGTGATGGATATGCAAATTATCCTTATCTGATCACTATACATTATATGTAGTGAAGCATCACTAT GTACCCCATGAATATGTATAATTGTTATTTGTCAATTTAAAAATAAAATTAAAAAAGAAAATGAAGTATA AAGGTATAATTTTTTTTAATCAATAAAACAGGCCAGGCACAGTGGCTCATCCCTGTAATCCTAGCACTTT AGGGGGCTGAGGCAGGCAGATCACTTTGAGCTCAGGAGTTTGATACCAGCCTGGGTATCATGGCGAAACC CTATCTCCAGGAAAAAAAAAAAAATCAATAGGAGAGATGTAAGGTAAAAGTGAGAAAGTTTCCCAGAATG ATAGACACACTGTTGAAGAGAAGAGCAAAAATGATTAGCAAATCGGAGAATCAACCCCAGAATTCTGATA TTTAACTAATATAAATTCTAGAAAGAAAAGACAAAAAATAGAAGGGCAAAAATCATTAAGGAACTAACAC ATAAAATGCTCCCCAGAACTGAAATATATAAATTTCCAAATTCAAAGGGCCTAATGAGTTCCTAAACTAA ATGTAAAAGTATCCAAACTAAGGCAGAGATGGTAATATTTCAGAAGACTAGGGCCAAATGTAAAAACATA AAAGCATCCATAAAGAAGAAAAAAATACTATGTTCATAAAAACATTGGGGAAAAACTCACATCAGAGTTC TTACTAGCAACACTGGAAATTATAAGAAAATAGACCAATGTTTTAAAAAAAATTCTGAGAAAAAAATACT CCAATCTAGAATTCTATATCTATTCAAACTATGTATCAAGTAAAGGGTAAAATACAGATATTTTTCTAAT ATGCAATACCTTAAAAATTCTGTCTCCTGTGTGTGGTTTCTCAAGAAACTTATGGAGTATGTGCTTCATC AAAATGAGGGAGAAAACTAAGAAAGAAAAATATATGGGACTTAGGAAGCAAGAAATCAAACAGAAGAAAA AAGACAAAGGGGATTACCAGGGCGTGGTGACCCCAGGTATGGACCCCAGGAGAAAAGCTGCCCAGCAGCC GGAGATACACCAGTCCAAAGGAAGCAAGAACTCCGAGGCTCTGGGAGTGCCACTTCCAAGGGGCGAAATG GACACGAGGGATTTCCTTACGGGGTTGTTGATGTAGCTCTGTTGTTGTTATTGTTGTTACCATATTAAGA GGAAATTTTAAATTTTGTTGGAAAATTCAGGAAGAATAAGTGATGGGTGCACAAAAAAGTACGTAAAAAG CTTTAAAAGGAAGGCAATTTTTAAATCAAAACCAAAGCAAAATATCGTTCAAGAAAATAAATGTCAGTGT GGTTCAACACATGAAATGACTACTTGGTTCAGCTGTGAAGAATATTTACATTGTCATGAATGTTAAATAA AAATTTAAACAAGAATTATGATAAAATTATTTTAGGAAGAGAAAGGAGGAAGAGAAGTGTGTGCGTGCGC GCGTATGTGCGTGCGCGCGTACGTGTGTGTGAAGTGATAGTTGTTGCAATATTAAATCCCTAGAGTAATA TTTAATATATTTTAAAATATCCATTTAAGCACATTGTTTAGAAATATTGGAATAAGTAGCAGAAGAAACT GCTCAGTTTCTTTATAAACCTCAAAGTCTTACTTAAAACTCTGTGAATGTGTTTATGTTTGCAAAAAATA ATTTAAAGGAGTCATCTAGTATTTCTGGGCGATCCATAAAACCTCTATTAAATACTAAAAGCTGCAGCCC TAATCCCAGTTACAGGTCAGACTACCAGACTTAGGGATATCCTGCAAAAAAATGTAGGCTGCCCACTACT TTCAAGAACCACAATAATATAACTGGTGTGTGGGAAAAGCCTTAGACCCAGAGTTCATCTGGAGACAACT TACTTAACCTCTCTGAGCCTCACTTGTCTCGTTTCTAAACTTAAAGAGTTCGTTCGGAACTAACTAAACT CAAATGAAAGGCAAATACCAAAAGTGAGACAGATCAAGCACAAACGCCAGCATCCCTTACAGAGGACAGT CTCAACTCAGATGCAGCCAACTGCTGTCATGAAGACCTGTTGTTGCTAAGAGGTCAGATGGTTCAAGAGA AACTGGAAATTTGGATTTTGACATGAAACCTCTGGAATTTAAAATACTAGTTTAAAATGCACAGTGCCTA CCAAACCAAACCTATCTGCAGGCCACCCCTAACTCACAGATTGCCAGTAAAGACCTCTAAATCAGATGAA CATTAATACCCTCTAGGTCTATTACTCTGTGGCAGTGCAGTGCTGCATGACTAAAAATCTTCACTGAATG AATGTGTTTCTTTACCACTAAACAGGCAGCGTGTTTTTACTCAACCTTGACATATGACTTTTTTTTTTCA TTATGAATACTCATGAATCTTAAGACCTGAGATCTGCACAGAGTCTTTACTCGAAGAAGTACTGTCATAA ACAGAGATAGGTTCTGCCGAACATGGCCGGACCGAAAAATCAGGGAGCAATTTTCACAGGTACACAATCG AGTAAGAACTGCCATCAATCTGTCTTTTCAGACATATTAATCCACAAAGATAGAAATCACTTTTATATGC CAAGGACAATATCAAGCTCAGTATTTGCTAAGACTATCTTTCAGTTTTTCATGAGGAAACTTTTCCCTGC CACTGATAATTATCTTCTTGGTTCACAGATCTGGAAAGCATGAAGACTGGGCTTTTTTTCCTATGTCTCT TGGGAACTGCAGCTGCAATCCCGGTAAATTTCCTTTCTTCTGTTATTACATCTCTTTCTCCTGACATTTA ATGCAGAAATCCTCCATTTAAAAGAAAATGTTCTTATATAATGGTTTGAAATTCTCTTTTTATTTTAATT ATATTCTTTATTGCCCAAGTAACAAACAAATAACTGGAAAACTCAAGATAAGGTACTTAAAAAAAAATTT TAGAACTATCAGGTTCTACAGGACACAATAAATATGCAGCAGAAAGTTTGGGCTATCAGTTTATTAGCCA TAGAATCAGCCCAAATACACAAGAGACAGGAAGAAATAAATTCTCCCAGGGAAGCTCATCACATTGTTAT TATAAACCCAAGATTTTAGGCCAGGTGCGGTGGCTCACGCCTGTAATCCCAGCACTTCGGGAGGCTGAGA TGGGCGGATCACCTGAGGTCAGGAGCTCAAGACCAGCCTGGCCAACATGGCAAAACCCCGTCTCTACTAA AAAATACAAAAATTAGCCGGGCATGGTGGCGGGCACCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAAG GAGAATCAATTGAACCCAGGAGGCAGAGATTGCAGTGAGCTGAGATCACTCCACTGCACTCCAGCCTGGG CAACAGAGTGAGACTCCGTCTGAAAAAAAAAAAATACTTAGGGTGCATATCCACGGTCTCCAGCAGCATT TTCTTCAAGATCAAATAGATGCTGGCTGAGAAATTTTGAGAGTCTATAATGAAAACAGAAACCAATGGTT TAGGCAGGAAACGATATGGTAATCATAAATCAGCTCCTAATTCACCCTTGGGAGGCTGTCCAAGCAAGTA TGCTGAAAGTAGGCAGGGCTAGAATATTCTCTTCTTCATGGTCAGATATATTGGCCCCATTTGCACAGCA ATAAAGCAGCTGTACACAAATCAGATCATTTGAAACCGTGTCAGTGGCCTCAAAACAAACTGAAAGTTAA AAAACAAATGAAACCATAGCATGAATGACCACTGGAGATGTTCTGCAAATGATTCATGTAATCCTTCATT AAACCAAAGGATTCGTGCCATATTTTTTTTCTTTTTCACCAAATGGAGGAATCAGCCTCCTTTAAAGAGA CAAAACAATTTCTCAATCGTCCCTTTCCTCCCTTCTTCTCTAGGTCTAAAATTCTGTCCTTGCTTTTTGG ATAAGTTGTTAGCTAGCTTCTGGTTGACAAATGTGTCAGCAAAAACAAACTCCATGGCACCCAGACCAAG CTGTTCTTGGAAGACAGAGTTTATACCCACCATCAGGAATCATGCTTAAGTAGTATGGAGCTACTCTAGC TGAAATTATACATTACACCCTGAAATCACAAAAGCGGGACAAGTTAATGTTCAACACTGAAAGGAGTTCC CACAAAACCGTTGTTTTCTCCTGAAAATGTGCTTTGTCCTTGTGGCTGTTGCTGTTATGTAAATAAACAT TAAAAAGTGTCTTTGGGCCACGCACAGTGGCTCCTACCTATAATCCCAGCACTTTGGGAGGTCAAGGCCA GAGGATCGCTTGAGCCCAAGAGTTCAAGACCGGCCTGGGTAACATAGTGAGGCCACGTCTCTACAAAAAA ATAAATAAAAAATTAGCCAGCTGCCATGGCATGTGCCTGTAGTCCCAGCTACTTGGGAGGCACAGGAGGG AGGATCCCTTAAGCCAGGGTAGTTGAGGCTGCAGTGAGCCAAGATCGCACACAGCACTCCAGCCTGGGTG ACAGAGCAAGACTGCCTCAAAAAACAAAAAAAGTGTTTGAACCAAATGTTTGAATGACACACTTGCATTT AGACACATTCCAGATGTTTCCTTTCTGGGACAATTTGATATCATGTAAACCTAGCCAAACTGCTAGAAAG CTAAGTATCTTCTCATAGAAATGACCTATTAAAAATTTGTATAATTTTCCCTGCCTGCCTGAATTCTCCA GATGAAAATGGATTCTGTGTAGTTGGGAGATTCCAAATAGATTTCCAGAGTTAAATAAATAGAAATATGC CCATAGTGATAAAACATAATTTCAATTGCAGAATATTTCTGAAAGTAAAAGAGCTGCCATTTTTTGTGTG CATTTCTTCCTGCTTGGGCAGTAGGCGGATGGAGGGGGAGAGAGAGTGACCAGTTCTCCACTAATAAGCC TAAAATCTCCCCCATCCATTGCCTTCTATGATGCCCCCTGCTGGCAGCTTACCAAAGTGGCCACCATTCT TTCTCCTTTTCCCCCTTCTTTAAGGCTTCTTTATAAACTTTTTCAAATTCATTACCCATCTTAGGTGAAA AGGAGATAAGAAGCAAAGGAGCAAACCAAACCTAATATGAATCCTGTACTTTGGCCAGAAGCCGTGGCTC ACATCTGTAATCCCAGCACTTTGGGAGGCCAAGGTGGGCAGATCACTTGAGGCCAGGAGTTTGAGACCAG CCTGGCCAACATGGTGAAATCCTGTCTCTACTAGAAAAATAAATAAATACAAAAATTAGCAGGGCATGGT GGCAGGCACCTGCAATCCCAGCTACTCAGGAGGCTGAGGCATGAGAATTGCTTGAACCCAGCAGGTGGAG GTTACAGTGAGCCAAGATCACCACTGTATTTCAGCCTGGGCAACAGAGTGAGACTCTGTCTCAAAAAAAA GTTTAAAAATAAAAAATAAATCCTGTACTCCATGACTATTACACAGTCAGCACTACAGGACCTGCTAATG GAATAAAAATAAGTTAATCCAAATAGAATCTCAGTTTCATACTTACACCTGGATAGGCCATCTGAGTGTC CAGAGTATCTCTCTAATAAAGATCCATGGTGAATATCTGCCTCAGATACTGGGCAGTTTATATTATTGAC ACAGTGTGACATTAGTACTAGAAATAGTAATTTTCAGTTGGGCAACTCCTTAAAATTTATAACATATTTT TTATACATAATCTTATTTTGATATTTCTGCTCACTTGATATTTCTTGCCACCTTGAGAGATGGCAGGGTA GAAATTAATGACCTTGGCCGGTCATGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCAAGACAG GAAGATTGCTTGAGTTCAGAAGTTCGAGGCCAGACTGGGCAACATGGTGAAACTCCATCTCTACAAAAAA TACAAAAATTACCCAGGCATGGTGGTGCCTATAGTCCCAGTTACTGGGGAGGCTGAAGTGGAAGGGTGGC TTGAGCCTGGGAGGCAGAGGTTGCAGTGAGCCGAGACTTCATCACTGAACTCCACCCTGGGCAAGAGGCT GGAGTTAATTAATTAAAAATTAATATAATGAATTAATTTTATTAATGTTTTTTAATTAATAAAAAATATT AACGACCTGTCAAACCACAGATAGAAAGTAAATAGCAGAGGCAAGACTTGAATGGAGGCCTCTTACCTCC AAGTTCAGTTGTTCAACTTCCCCATCATGCATCACTGCCCAGCTCTTTATCCAAGTCTCCAATCTTGCTA GAAATAGGACCATCCCTCTAATAGAAATTAATACTCCAGACATGCCCTTTTCTACTTAGGCTTAGTGCCC TGTCTCACACAGTCTGAATTAATTCTAATTTTTTTTGTTTTTGAGATGGAGTTTCACTCTTGTTGACCAG GCTGGAGTGCAATGGCACAATCTCAGCTCACTGCAACCTCCGCCTCCAGGGTTCAAGTGATTCTCCTGCC TCAGCCTCCCGAGTAGCTGCGATTACAGGCACCCACCACCACACCCAGCTAATTTTTTGTATTTTTAGTA GAGACGGGGTTTCACCATGTTGTCCAGGCTAGTCTTGAACTCCTGCCCTTGACCTCAGGTGATCCACCCA CCTCGGCATCCCAAAGACCTGGGATTACAGGCGTGAGCCACCATGCCCAGCCCCATTAAGATTTCCTGAC CAACGTTAAGGCCAATGGCGTTAAGAAATCAAATAAATATTGATAAAAAGTTTATAAATTTTTCTGCTAA TTATCGGTGGGTACTTAAATTAGGCAAATGTACAATACTATATCCTATGGTTAATTTTATTTGACTTCAA CTTTCTGCTAAACAACACTTTCCAAAATTGTAAAGTACAAATGCTTTGCAAAAGTTTAAAAAACACAGAA AATAATTTCAAAACTCAAAGTTACCATTATTTAAATGCATTTTGTTTTATTTTCACCCAGTCTCTGCATA AATAACTTTTTCTTAAACACAATTGAGATTCTGCTTCCACTTAACATTCTGTTCTAGGCATCTGCTTATA TCCTCAAAAACTCTAGAGAATATTTTTAAATTGTTGGTATAAATGAAGTATATTGCTACTAATAATGATG ACAACAAGAGTAACTAGCAAATTTGTAAATTAGCATCCAGACATGAATAACAAAAACCAGTTTTTAATTT TTTCAGACAAATGCAAGATTATTATCTGATCATTCCAAACCAACTGCTGAAACGGTAGCACCTGACAACA CTGCAATCCCCAGTTTAAGGGCTGAAGCTGAAGAAAATGAAAAAGAAACAGCAGTATCCACAGAAGACGA TTCCCACCATAAGGTAAAAGTAACATCATTTATATTAATACAATTTTTTAATTCTCCAAAGGTCTTAGTT TCAAAGCATGGTAAAAGAGATTATGTTATTTATGTCTCAGTTTAATTTTTTTAAAACATGATGATCACCT CAACTGCCTCCAATCACTAGAAGAATGATGAGGATTAATGAGTTTTACTACTTGGGCTGAGCTGCTGTAT ACTTGTTTCATTTTATAAAATCCAAATTCAGTTTAAACCTGTGGCTACAGAGTGTGAGGAATATTATAAA CATGTTTACATGATAGTGTGTGAAGAAAAAGAATAATGAATATTAAATGTTACCTTAGGCATAAATATGG TTACATTATCATTTGTTTGAAGAATGAACTTTTTTTTCTTTTAAGGCTGAAAAATCATCAGTACTAAAGT CAAAAGAGGAAAGCCATGAACAGTCAGCAGAACAGGGCAAGAGTTCTAGCCAAGAGCTGGGATTGAAGGA TCAAGAGGACAGTGATGGTCACTTAAGTGTGAATTTGGAGTATGCACCAACTGAAGGTACATTGGACATA AAAGAAGATATGAGTGAGCCTCAGGAGAAAAAACTCTCAGAGAACACTGATTTTTTGGCTCCTGGTGTTA GTTCCTTCACAGATTCTAACCAACAAGAAAGTATCACAAAGAGAGAGGAAAACCAAGAACAACCTAGAAA TTATTCACATCATCAGTTGAACAGGAGCAGTAAACATAGCCAAGGCCTAAGGGATCAAGGAAACCAAGAG CAGGATCCAAATATTTCCAATGGAGAAGAGGAAGAAGAAAAAGAGCCAGGTGAAGTTGGTACCCACAATG ATAACCAAGAAAGAAAGACAGAATTGCCCAGGGAGCATGCTAACAGCAAGCAGGAGGAAGACAATACCCA ATCTGATGATATTTTGGAAGAGTCTGATCAACCAACTCAAGTAAGCAAGATGCAGGAGGATGAATTTGAT CAGGGTAACCAAGAACAAGAAGATAACTCCAATGCAGAAATGGAAGAGGAAAATGCATCGAACGTCAATA AGCACATTCAAGAAACTGAATGGCAGAGTCAAGAGGGTAAAACTGGCCTAGAAGCTATCAGCAACCACAA AGAGACAGAAGAAAAGACTGTTTCTGAGGCTCTGCTCATGGAACCTACTGATGATGGTAATACCACGCCC AGAAATCATGGAGTTGATGATGATGGCGATGATGATGGCGATGATGGCGGCACTGATGGCCCCAGGCACA GTGCAAGTGATGACTACTTCATCCCAAGCCAGGCCTTTCTGGAGGCCGAGAGAGCTCAATCCATTGCCTA TCACCTCAAAATTGAGGAGCAAAGAGAAAAAGTACATGAAAATGAAAATATAGGTACCACTGAGCCTGGA GAGCACCAAGAGGTAAAATTATTTTAAATGGTCCTTGTCCAATAAAGCCAGCATTATCAATAAACAGTCA TGACCTTTCTCTGTGCTCTCACAGTGTCCTGTATGGATGTCTACTAGTACATTACTAAAATATATTACAG TTATTTCTTTTTAGGTCTATCTCTATCATTAGGCTGAGAATGCCTGTTTTATTTGAGTTCCCGTAGATGC AGATCTTGGATTTGAGTGTTGTTTATTTAAGAAGCACAGGGAACAAAGAGGAGTGCAGAAGTAACACAAG AAGGAAAGGAAGCTAATAAAAGGAACATCATTCAAGCCATGTAAAGACATTTTCTCAGAAGTATTCCATT TGGCGACTGAAGGAGCTAGGGTACTTCTTTTGGCTGAGGATTGCTAGAGGGGTATTAATTTCCCAGCATT TCCAGCCTGTCCCTTGAGTGAGCCAGGTCAATTTCCATGATTTTTCAGGCACGGAAATGCAGATATTGGC CATTGAAAGTCCCTGGAACTAGCTGGAATGATAAATTATGACAGATCTGAAGGATAGGAGATACTGGCAA CTGCTGCTCTAATGCCTTGAAAGCAGATGCCATATTGTTTTCGAGTTGAATCACCAGTGTCCAACAAAAT GTCTCTGACATAACAAAAGAGCCAACAATGTTTGTTGAATTAGTTATAAAGATTAAGGTCCTACTTTATT AAGCAAACACATACCAAAATGATAATCTGGAAACTACAGCAGGATCGGGGCAGGGAGGAAGCATATTTGG AGCTTTCATTCAAAATCCTGGCAGCCACAAAGTCCTGTGCCAGCAGGACTTGGCACAGATTTTGGTACAC AAGGTCAATGGTAACCTCAGTTACTGAGAACTCTGCTGCCACTCTAACGTAGGAGTTTTCTTATACCTTA AAAGCCTGGTATGAAAGCTTTACCAACAAATTCAGAGAGATTTCCAATGTAACTCTGGCTTAACTACAAA ATCACAAGATAATACTACATTTCTAGTGTTTTCTCAAATCCAAAGAGGAGACTCCAAGTCTTATTGAGTA ATCCCCAGAGATAACGCACTAAATCTCACTGATAAAGATAGAAATGGGTCCTGTTCTCCAAGGGTTACTG TCTACCTCCACAGTTGTGACTGATTTCCCTTTCTTTTTTCTTTTTTTTTTTTTTTTGAGACGGAGTCTCA CTCCTTCACCCAGGTTGGAGTGCAGTGGCGCAATCTCGGCTCACTGCAACCTCTGCCTCCCAGGTTCAAG CAATTCTCCTGTCTCAGCCACTCAAGTAGGTGGGACTATAGGCGCCTGCCACCATGCCCAGCTAATTTTT GTATTTTTAGTAGAGACAGGGTTTCACCTTGTTGGTCAGGCTGGTCTCGAATTCCTGACCTCAGGTGATC CACCCACCTCAGCCTCCCAAAGTGCTGGGATTACAGGCTCCATTTCTTCTTTTTTTTCTGTTTTGTTTTG TTTTTAGAGATGGAGTCTTGCTCTGTCTCCTAGGCTGGAGTGTAGTGATGCAATCACAGCTTACTGCAAC CTCAACCTCCTGGGCTCTAGCAGTCCTCCCACCTTAGCTTCCTGAGTAACCGGGACCACAGGCATGCACC ATCATGCCCAGCTAATTTTTTTTTTTTTGGGGGGGGGGGTGGGTAGAGATGGAGTTTCCCTATGTTGCCC AGGTTGGTCTTAAACTCCTGGGCTCAAGTGATCCTCCCACCTTGGCCTCCCAAAGTGCTGGGATTACACA TGTGAGCCACCACACCCAGCCTGGTTTCCCTTTCTGAGATTTGAAATGATTTGAGCATGAAAAATACTCG TGAAAGTATGCACAGTGGAAATATAAATTAAGTAATGGCTCTCCTCTTAGTAGATTTTAACTTTTGCTCT TGTTATTCTAAAGGCCAAGAAAGCAGAGAACTCATCAAATGAGGAGGAAACGTCAAGTGAAGGCAACATG AGGGTGCATGCTGTGGGTGAGTATGCATGAAGCAAGCTGTTTGTGACTATATCAAGGAAGAAATGGAATC TGCCACTTTGGGCTTGTCCCTCCATCCTTTGTGAATGCTGCACAGAATTTTTTCTCTCCCCAGTCCTCCC CAAGGAAATGCTCCCATAAATTGTTGACATTTTCTTGTGCATACTTGATATACAACAATGGGTAAATGTG TTTGCAAACTGGAAGCCCTGTTGAGATATTAGTGAAAGGGCTAGAGTTCTTCCTTAAATCCTTTTGCTTC TGAAAAGACTTAATTCTATCTTATTTATTCTCAAATCTGTAACTTGCTGATGAATTTATATCCCATACTT GATAAAGGACCTTATTCCTCCCCCTATCACAAACATTTTGAATTTCAGCCTTATTTCACTTCTGACCAGC TTGCACAACGTTGCACTAAGGACTTCAGACTATGACCATCTCAGGCATAGAAGAGCTGTCTGTTCTTTGC ACATCTCCAATCCAAACTGCTGCAAGAGGAAATCTAGATTATCATGTAAAATAATCAGTAAAATTATCAT GTAAAATAGAAGGTTCCATCTGACATTAACACATCAATTAAAGAGGATTCCAATGTCTTCCCACTTCCAA ATTTGCAAATTTCAAGGACTTCAAAATTTCCCCTTCATTAGTGAAAATGAAACTAGTTGAGTGAATTTGT ATTTACATACTCAATTTAACTTTGTCCATGCTTCCTGCCCAATCTTTTCTGTTAGATTCTTGCATGAGCT TCCAGTGTAAAAGAGGCCACATCTGTAAGGCAGACCAACAGGGAAAACCTCACTGTGTCTGCCAGGATCC AGTGACTTGTCCTCCAACAAAACCCCTTGATCAAGTAAGTATTCTGCAAAATAGTCTTTAAGTGGCTCCA AAAGGTTAGTGACTGAAATAAAAATATTTGCCATTGAAATTTTTGCTTAAAAAAGGTAGATACCTAGGTT ATCATTTGGTTATTTGGGATATTTGGAACATCTGCAGTTTTCATTCTACTGAGCTTATCTAGAGCTAAAT TGTCATCACCGTTGGTACAGTTTAGTTGATTTTTTTGATGCCAAATGGAACAATTACGATTTTAATAGTC TCACCTACCTGACCACATCTTTGGCACAGCGCTGTTATCAGCATATGAGCTTTAAGGAGCAGAGTGTCTT CCAGTGAGCATTTGGCTCTATCAGCTTTTTCTTCTACTTATCTTCCATAGGTTTGTGGCACTGACAATCA GACCTATGCTAGTTCCTGTCATCTATTCGCTACTAAATGCAGACTGGAGGGGACCAAAAAGGGGCATCAA CTCCAGCTGGATTATTTTGGAGCCTGCAAATGTAAGATTATGTCCCTCCTGTCAACCATCATCTCTGAGA GGGCTTGGGGTGAATCTGGACATGCCTGAATTATCTATATGCAAACAGGGAAAAGCTGATGTAGTTCTGA ACACAAAAATTATCAACTGGAGAAACTTAAAAAATAAGAACTCTCAGGCCTTAACCGTAGGAGATTCTGA TTTAACTGAACTAGGTTGGAATCCTGACATTGTTTTTTTTATTTGTTTTTGAAGTAACCTAGACAATTCT AATGTGCAGCCAGGGCTCAGAACCACTATGATAATGCTATCCACTTAATCACAGAGTTGAATCACTGGAA TTTTGCTACATTATTTGCCCTCTTCCCAATTTAAGTTAAGCCTTTGCCAAGAAGTCTCTGACAACACATT TTTCCAGAAGTGTTTTAAGGCTGTCTTCCTTCCCCAGGATATTCTCAATTGTGTTTGGCTCCCCTTACCA CTAAGTGATTCTCCACATTAGCAGTGCTCACTAATGTTTCCGGGTCTCCTCCCCTTCCAGACACAGGAGA GGATGAAACATGTCAGCCTCCTGGACGTTAGGTATGACCATATATCTTGCTTTGTCCAGGGAAATGTGAA AAAAGTCATCTATGTGAGTTCTGGGCAGAAGCATTCAAGAGCTGGGGTATGGTTCTCCATCCTCTGCTCC TTTGCCACCACAAACTCTCTTTGAGATAGTGGCCTCAAAAAATGGCAACGTCATTGGTGGCTGGCAAGAT GGCCAAATAAGGACCACTCTGGTTTGCAGCTCCCAGTGAGATCAACGCAGAAAGAGGGTGATTTCTGCAT TTCCAGCTGAGGTACCCAGCTCATTGGGACTGGTTAGACAGTGGGTGCAGCTCACAGAGGGGGAGCCAAA GTAGGGTGGGGTGTTGCCTCACCCAGTAACTGCAAGGGATCGGGAAACTCTCTCCCCTAGCGAAGGGAAG CTGTGAGGGACTGTGCTGCGAAAGACAGTGCATTCTGGCCCAGATACTACGCTTTTCCCACAGTCTTCGC AATCCACAGACCAGGAGATTCCTTCGGGTGCCTACACCACCAGGACCCTGGGTTTCAAGCACAAAACTGG GCCACCATTTGGGCAGACACCGAGCTAGCTACAGGAGTTTTTTTCCATATCCCAGTGGCACCTGGAATGC CAGCAAGACAGAACTGTTCACTTCCCTGGAAATGTGGCTGAAGCCAGTGAGCCAAATGGTCTAGCTCAGT GGATCCCACCCCCACAGAGCCCAGCAAGCTAAGATCCACTGGCTTGAAATTCTTGCTGCCAGCACAGCAG TCTGAAGTTGACCTGGGATGCTTGAGTTTGGTGGGGGGGAGGGGCATCCACCATTACTGAGGCTTGAGTT GGCGGTTTTCCCTTCACAGTGTAAACAAAGCTGCTAGGAAGTTCGGACTGGGTGGAGCCCACGGCAGCAC CAGAAAGCCACTGTAGCTAGACTGCCTCTCTAGATTCTTCCTCTCTGGGAAAGGCATCTCTGAAAGTAAG GCAGCAGCCCCAGTCAGGGGTTTATAGATAAAGCTCCCATCTCCTTGGGACAGAGCACCTGGGGGAAGGG GCGGCTGTGGGCAGAGCAGACTTAAATGTTCCTGCCTGCCAGCTCTGAAGAGAGCAGCAGATCTCCCAGC ACAGCACTCAAGCTCTGCTAAGGAACAGACTGCCTCCTCAAGTGGGTCCCTGACCCCCATGCCTCCTGAC TGGGAGAAACCTCCCAGCAGGGGTCGACAGACATCTCATACAGGAGAGCTCTGGCTGGCATCTAGCAGGT ACCCCTCTGGGACGAAGCTTCCAGAGGAAGGAACAGGCAGCAATGTTTGCTGTTCTGAAGCCTCTGCTGG TGACACCCAGGCAAACAAGGTCTAGAATGGACCTTGAGTGAACTCCAGCAGACCTGCAGCAGAGGGGCCT CTTAGAAGGAAAACTAATGAACAGAAAGGAATAGCATCAACATCAACAAAAAAGATATCCACACAAAAAC CCCATCCAAAGGCCACTAACATCAAAGACCAAAGGCAGAAAATCCATGAAGATGAGGAAAAACCAACACA AAAAGCCTGAAAATTCCAAAAATGGGAATGCCTCTTCTCCTCCAAAGGATCACAACTCCTTGCCAGCAAG GGAACAAAAGTGGATGGAGAATGAGTTTGAGGAAGTGACAGAAGTAGGCTTCAGAACATGGGTAATAACA AACTCTTCTGAGTTAAAGGAACATGTTATAACCCAATACAAGGAAGCTAAGAACCTTGAAAAAAGGTTAG AGGAATTGCTAACCAGAATAACCAGTTTAGAGAAGAACATAAATGACCTGATGGAGCTGAAAAACACAGC ACGAGAACTTCGTGAAGCATACACAAGTATCAATATCCAAATCGATTAAGTGGAAGAAAGGATATCAGAG ATTGAAGATCAACTTAATGAAATAAAGCATGAAGACAAGATTAGAGAAAAAAGAATGAAAAGGAATAAAC AAAGCCTCCAAGAAATGTGAGACTCTGTGAAAAGACCAAACCTACATCTGATTGGTGTACCTGGAAGTAA TGAGGAGAATGGAACCAAGTTGGAAAACACTCTTCAGGATATTATCCAGGAGAACTTCCTCAACCTAGCA AGACAGACCAACACTGAAATTCAGCAAATACGGAGAACACCACAAAGATAATCCTCACGAAGAGCAACTC CAAGACACATAATTGTCAGATTCACCAAGGTTGAAATGAAGGAAAAAATGTTAAGGGCAGCCAGACAGAA AGGTCGGAATACCCACAAAGGGAAGCCCATCAGACTAACAGTGGGACTCTCTGCAGAAACCCTACAAGCA AGAAAAGAGTGGGGGCCAATATTCAACATGCTTAAAGAAAAGAATTTTCAAACTAGAATTTCATAACCAG TCAAACTAAGCTTCATAAGTGAAGGAGAAATAAAATATTTTACAGATAAGCAAATGCTGAGAGATTTTTT CACCACCAGGCCTGCTTTACAAGAGCTTCTGAAGGAAGCACTAAATGTGGAAAGGAAAAACCAGTACCAG TCACTGCAAAAACATACCAAATTGTAAAGACCATCGACACTATGAAGAAACTGCATCAACTAATAGGCAA AATAACCAGCTAGCATCATAATGACAGGATCAAATTCACACATAACAATATTAATTTTAAATGTAAACGG GCTAAATGCCCCAATTAAAAGACACAGACTGGCAAATTGGATAAAAAGTCAAGACCCATCAGCATACTGT ATTCAGGAGACCCAGCTCACATGCAAAAACATACATAGGCTCAAAATAAAGGGATGGAGGACTATTTACC AAGAATTGGAAAGCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAGCAGGAATTGCAATA CTAGCCTCAGATAAAACAGGCTTTAAACCAACAAAGATCAAAAAACACAAAGAAGGGCATCACATAATGG TAAAGAGATAAATGCAACAAGAAGAGCTAACTATCCTAAACATATATGCACCCAATATAGGAGCACCCAG ATATATAAAGCAAGTTCTTAGAGACCTACAAAGAGACTTAGACTCCCACACAATAATAGTGGGAGACTTT AAAACCCCACTGTCAAAATTAGACAGATCAACAAGACAGAAATTAACAAGTATATTCAGGACTTGAACTC AGCTCTGGACCAAGCAGACCTAATAGACATCTACAGAACTCTCCACCCCAAATTGACAGAATATACATTC TTCTCAGCACCACATTGTACTTATTCTAAAATTCACCAAATAATTGAAAGTAAAAACTCCTCAGCAGATG TGAAAGAATGGAAATCATAACAGTCTCTCAGACCACACTGCAATCAAATTAGAACTCAGGATTAAGAAAC TCACTCAAAACTGCACAAATACATGGAAACTGAACAACCTGCTCCTGAATGACTACTGGGTAAATAACGA AATTAAGGCAGAAATAAGGAAGTTCTTTGAAACCAATGAGAATGAAGACAAAATGGGCCAGAATCTCTGG GACACAGCTAAAACACTGTTTAGAGGGAAATATATACCACCAAATGCCCATAAGAGAAAGCAGGAAAGAT CTAAAATTGACACCCTAGCACCACAATTAAAAGAACTAGAGAAGCAAGAGCAAACACATTCAAAAGCTAG CAGAAGACAAGAAATAACTAAGATCAGAGCATAACTGAAGGAGATAGAGACACGAAAAACCCTTCAAAAA ATCAATGAACCTAGGAGCTGGTTTTTTTAAAAGATTAACAAAATAGATAGACAGCTAGCCAGACTAATAG AGAAGGAAAGAGAGAAGAATCAAATAGATACAATAAAAAATGATAAAGGGGATATCACCACTGATCCCAC AGAAATACAAACTACCATCAGAGAATACTATAAACACCTCTATACAAATAAACTAGAAAATCTAGAAGAA ATAGATAAATTCCTGGACACATATACCCTCCCAAGACTAAATCAGGAAGAAGTTGAATCCCTGAATAGAC CAATAACAAGTTCTGAAATTGAGGCAGTAATTAATAGCCTACCAACCAAAAAAAGCTGGGGACCAGACAG ATTCACAGCTGAATTCTACCAGAGGTACAAAGAGGAGCTGGTACTATTCCTTCAGAAAGTATTCCAAACA ATAGAAAAAGAGGGACTCCTCCCTAGCTCATTTTATGAGGCCAGCATCATCCTGATACCAAAACCTGAAG GATATACAAAAAAAAAAAAAAATTCAGGCCAATATCACTGATGAACATGGATGCGAAAATCCTCAATAAA ATACTGGCAAACCAAATCCAGGAGCACATCAAAAAGCTTATCTACCACAATCAAGTCACCTTCATCCCTG GGATGCAAGGATGGTTCAACATACGCAAATCAATGCGTGTAAGCCATCACATAAACAGAACTAATGACAA AAACCACATGATTATCTCAATAGATGCAGAAAAGGTCTTCAACAAAATTCAGTATCCCTTCATGCTAAAA ACTCTCAATAAACTAGGTATTGATGGAACATATCTCAAAATAATAACAGCTATTTATGACAAACCCATAG CAAATATCATACTGAATGGGCAGAAGCTGGAAACATTCCCTTTGAAAACCAGCACAAGACAAGGATGCCC TCTCTCACCACTCCTATTCAACATAGTATTGGAAGTTCTGGCCAGGGCAGTCAGGCAAGAGAAAGAAATA AAGCGTATTCAAATAGGAAGACAGGAAGTCAAATTGTCCCTGTTTGCAGATGACATGATTGCATATTTAG AAAACCCCATCATCTCAGTCCAAAATCTCCTTAAGCTGATAAGCAACTTCAGCAAAGTCTCAGGATACAA AATCAATGTACGAAAATCACAAGCATTCCTATATACCAATAACAGACAAGCAGAGAGCCAAATCATAAGT GAATGCCCATTTGCAATTGCTACAAAGAGAATAAAATACCTAGGAATACAACTTACAATGGATGTGAAGG ACCTCTTCAAGGAGAACTACAAACCATTGCTGAAGGAAATAAGAGAGGACACAAACAAATGCTCATGGAT AGGAAGAATCAATATCGTGAAAATGGTTGTACTGCCCAAAGTAATTTATAGATTCAATCCTATCCCCATC AAGCTACCACTGACTTTCTTCACAGAATTAGAAAAAAACTACTTTAAAGTTGGGAACCAAAAAAGAGCCC ATATATCCAAGACAATCCTAAGCAAAAACAACAAAGCTGGAGGCATCACGCTAACTAACTTCAAACTATA CTACAAGGCTACAGTAACTAAAACAGCATTGTACTGGTATCAAAACAGATATATAGACCAATGGAACAGA GCAGATGGCTCAGAAATAATGCCACACATATACAGCCATCTGATATTTGACAAACCTGACAAAAATAAGC AATGGGGAAAGGATTCCTTATTTAATAAATGGTGCTGGGAAAACTGGCTAGCCATATGCAGAAAACTGAA ACTGGATCCCTTCCTTACACTTCATACAAAAATTAACTCAAGATGGATTAAAGACTTAAACATAAGACCT AAAACCATAAAAACCCTAGAAGAAAACTTAGGCAATACCATTCAGGACATAGGCATGGGCAAAGGCTTCA TGACTAAAACACCAAAAGCAATGGCAACAAAAGCCAAAATTGATTAATGGGATCTAATTAAACTAAAGAG CTTCTGCACAGCAAAAGAAACTATCATCAGAGTAAACAGGCAACCTACAGAATGGGAGAAAATTTTTGCA ATCTGTCAATCTAACTAAGGGCTTATACCCAGAATCTACAAGGAACAGATACAAATTTACAAGAAAAAAA CAACCCCATCAAAAAGTGGGTGAAGGATATGAACAGACACTTCTCAAAAAGAAGACATTTATGCAGCCAA AAAACATATGAAAAAAAGCTCATAATCACTCGTCATTAGAGAAATGCAAATCAAAACCACAATGAGATAC CATCTCTCACCAGTTAGAATGGCGATCATTAAAAAGTCAGGAAACAACAGATACTGGAGAGGATGTGAAG AAATAGGAACGCTTTCATATTGTTGGTGGGAGTAAATTAGTTCAATCATTGTGGAAGACAGTGTGGCAAT TCCTCAAGGATCTAGAACTACAAATACCATTTGATACAGCAATCCCATTACTGGGTATATACCCAAAGGG TTACAAATCATTCTACTATAAAGATGCATTCACACATATGTTTATTACAGCACTGTTCACAATAGTAAAG ACTTGGAACCAACCAAAATGCCCATCAGTGATAGACTGGATAAAGAAAATATGACACATATACACCATGG AATACTATGCAGCCATAAAAAAGGATAAGTTCATGTCCTTTGCAGAGACATGGATGAAGCTGGAAACCAT CATTCTCAGCAAACTAACACAGGAACAGAAAACCAAACACTGCATGTTCTCACTCATAAGTGGGAGTTGA ACAGTGAAAACACATGGACACAGGGAGGGGAACATCATATACCAGGGCCTGTCAGGGGCTGGGGGACTAG GAGAGGGATAGCATTAGGAGAAATACCTAATGTAGATGATGGGTTGATGGGTGCAGCAAACCACTATGGC ATGTGTATACCTATGTAACAAACCTGCACATTCTGCACATGTATCTCAGAACTTAAAGTATAATTAAAAA AAAAAAAAAACGGCAGTGATCCTGAGCTCTGGGGAGACTGCAATGAGCAGAGCCCTCCTGCCAACTTGTA TTGGACTTGTAGCAGGATTGCAAAATTGACTTCTGTTTCTTTAAGCCACTGAGATTTAGCATTATTTCTT ACTGTAGTATCAGCTAATAGCTACCTTTTTCTCTATTCAATAGCACTTGTGCCCTCCACCTACAAATTTC AACTCTGATTCTACAGCAGTGATTCTGGGGCCTAGCTGCACATCCAAATAGATCTTGGAGCTTTAAAAAC ATCCTGATGCCCAGACTTCACGCCAGACCAATCACATCAGAATTTACTTGATTGGAAGCTGGCATTTGGT ATGTTTTTTAAAACCCCAGGCAATTTTGTTGTGCTGCTGCCAGGGCTGAGGACCACTGTCATAATAATGG GGACCTGAGAAAGCTCTGTCAGTTGCCAGAAGTCGTTAAGCTTCCTATTATGAGGACTTGCCATAGGACA CAAATAAGCCCAAAGATTACAGTACATTTTCTGCTTGTAACAGCTATTCCTACTTGTACGGACTTTGAAG TGATTCAGTTTCCTCTACGGATGAGAGACTGGCTCAAGAATATCCTCATGCAGCTTTATGAAGCCAACTC TGAACACGCTGGTTATCTAAATGAGAAGCAGAGAAATAAAGTAAGTTATCCACAGGTTAGCTTCTTCAAT GTCTGTCTACAGGGCATGAGGAAGAAAGACGTGGTGGGGGGGCTACCTACCTCTGCATACTGGCAAAAGC CCACTATGCTTCCCCATGCCCGGTTAGCCCATGTGGCTTAACAGAATAATAGATGTCACCATTCACGCCA CAAGGTTTCAGACACCACCAAACCGCCCCATTCTTCCCAATGGTCAGTGGCCTGAATTAGGGCTCTTCAA TTCCTACCTAGAGCAAGCTCTGGTTGAGCAAAGTTAATATAAATTTAGCATTGATCTAGTCAGTCCAAAC ATCTTATTTAAATCTAAGCATTTGTTTTGTTCTCATAGGCCAGACATAGATGTATGATATAAAGTAAATC CATTACTCAAAATATCAGTAATATATTAAGATTAAAAAGCACAGAACATTGATTCCAAAAGCTTCCAGAG AAAATTCATTCACCAGATAGTTATTGAGTGTATCCTGGGTGCCAGAAATTGACCTAAATACTGGAGATAC AGCAACGAAAAGAAAATCTCTGCCTTCATGAGTTTACATTCTGGGTGAAGAGACAGACTCTAAACAAATA AGTATATATGTGTGTGTGTATGTAATGTTTGTATATGCATATATTTGTACATACATATATATGCATATAT GCAATTATATATAGTAAAATGAGCATTTATGTAAATATAACCAAATCAGCAAATATATGTATAAGTATGT CAGTTGGGATTAAACATGGTGTGAAGACAAATAAAACAAGAAGGAGGGTGTGCATTAACTGTGTCAGATG CTGTTTATAGGTTATGAGTTGAAGACTGAGAATTGGCCAGGGATTTAGCATGTCAAAGTCATAGCTGACC TTGATAGGAACTGTTCCTGGGGTGGGAGCATGTTTCAGGAGGGAAGCTCCAGTGGACAGAGTTCAACAGA GACTAGGAGGAATGGATGCAGCAAGTATAGACAATCCTTTCAAGGAGTTTTGCTATGAAGAGATAAAGAG AAATGGGGTGGCAGCTGGAGTGGAAAGTGAGTACAAGAGTCCCACCTAGCAGTGGGAGATGGTAGAGGAT GTTTGCACGCTTCTGGAAATAACCCAGTCAAGAAGGAAATGTTAGTGGGGAGCAGAGAATGCGCACAACT GCCAGAGGGCGTTCTTCGATACATGTCCCACCCAGAGGAGAGGGATTGGACTTAGGTTAGGAGCACAGGA AGGTCGCAGGGAGCAAAGTTGTGGTTCTGGGAGCAGGTGGAGGTCCTGTTTGCTTCCAATTACTCAGTGA AATAAGAGGCAACATCACAAGCTGAGAGTTTCACAGGCACTGCTCAAGAATAATTTCTAGCCCCCGTCTT GAATACCTTGTCACAGAGAGCCTTGAGGGTATTAGCTATGAAACAGGGAAATTTCAATGGGGCTGGCCAA GCAATAACACACCAGGGTGAAAGCAAGACTGAGTGGGCACTGGATGGATGACCTAGAAGACTAAGAGTGG ACTCTGTCATCGGGGGAAGGAGCAGCACTTTTCACTAACTAATCACCTTAGTCAATTCAGCCCTTTTCAT TAAAACCTCATAGTTTAAAAAAAAAAAAAAAAAGCAGCGAACATTACTTGGTTAAAAGAAAGAGGCAAAA CATACTTAAAATATTTAAAAGTTTAAAAAAGAATTTAAATTTCTTCTAAAAACCAGAGGTTTCTTACATC AGGTGCTATTCTGTGTAGACATGAGAAAGGCCTGTAGTATTGATTGGAAGGAATTTCATTTAGTTGCACA TGATGTCCTGAGCTTGTTTTCCCCTATCGTGTTACTGTCACTCTTCAAGTAAAGTTTATAGCAAGTGACA AGTCCATTACATTTGTCTGATTCTCTGACAGTCTTCTGCCTTCCTAATCCCAGGTCAAGAAAATTTACCT GGATGAAAAGAGGCTTTTGGCTGGGGACCATCCCATTGATCTTCTCTTAAGGGACTTTAAGAAAAACTAC CACATGTATGTGTATCCTGTGCACTGGCAGTTTAGTGAACTTGACCAACACCCTATGGATAGGTAAGAAC TCTTTACCTTTCCATTTCTAGATTTATCTCTCTGATAAAATATCTACATATCTATGCAAAAGGAAAATCT AAACAGATTTAGGACATTTCCCAGTTCCATTTTAGAATACTGAAATGCCTGGTTAGGAGTCTAAACACAA AGCTGCTGTGTATGATGTACTCTAGAACTTAAGGTATAATAATAATAATAAAAAAGTCTGAAACTTGATA GAGCTTATGTTGATAAAGTTTATGTTTTATAATTTTATCTTTTAATTCCATTTCTCAATGAACTTTTTGA AGTCCCCTTATCACAATTATCAAAGCTATGTAATATTCATTAAAAAAAAAAAGCTGCTGTGAAGATAGCA GAATATGGCTACACCACAGCTCCCAAGTTTACATGTTAAGGTCCAGCTTCCCACAGATACTCCTCCAACT TTCTCATTCTTGATCGTAAATTCCCAAGATTGGCCCAATGTGGGTCAAGTGACTACATCTAAAACAATCA GGTATGGCCAGTAGATGAGAACCAGGTTGTACCAACATGACTGCTGGGTACACCCCTATAGATTTAGGGT GGGGGAAGGACAGTTCCTGTGAAGACAGAAAACTTGTGAATCAACATCCCAAAAGCTGTCAACCTTACCC ACAAATACTTTATTTCGTTGGCAGTTTTTATCTGTATTCTATTTATATCACATATACAGCAACCTTATGG GAGAAAAATGTCCTTGGTGAGCCTGAGAGTTAAATCTTCATGCACAAGCTACTCAATTAATAGGATGCCA TGTATTTCATTGCAGAGTCTTGACACATTCTGAACTTGCTCCTCTGCGAGCATCTCTGGTGCCCATGGAA CACTGCATAACCCGTTTCTTTGAGGAGTGTGACCCCAACAAGGATAAGCACATCACCCTGAAGGAGTGGG GCCACTGCTTTGGAATTAAAGAAGGTAAATTCATCACCAGCCAAAGAAGAGGGATGTCTTCTTCCTCAGA CAAGCCCTAAGCCCTGCATGCTTCATAGAGAGGTCCTGCCACATGTTCGAATTGGAAGCTAGAAAAAAAA AGGTGGCAGCTTCCCAGATAGGACTCCCTTGGTGCACATGCTGTCATTGCGAAGTCACTTCTTACTACCT TTATGGCACTGTTTTCAAAGGGTAGCAAGGGTGAACATGCATTGAGGTCTCAACAGTCAGCTAAGCCTAG AAAGACGTGTGAATCCAGAATTGGGCCAAATCTCAGCAGGCTTTGTGTCCTTCCTTATTTCATATCCTAC CTTAACCTGGGCCTTGGGCCAAACTTTTCAAAATTACACATAAAGAATAAAAAAGCAAGCCCATTTCTGA CAATGGGAGATGTCAGAACATCTCAGAATCCATTACCAACACACTAAAGACTGGATTTTACATCACAATT AGTGCTGGGATAATCCTTTAACCCAAAACTCACCCATGGCTTCACCCTCAATGAATGGGAGCTGTGGGAG GGTAGATCAGAGTATTCTTTCTTTACTCCTGCAGTGGAGGAAATTAAATTTAGATGCTTGTTTTGCTGGG TTATGTCTTAATATGTTTCCTTTTCTTTCCTTAAGTTAGGCTTGAATTTTATGAGCAAGTATGTTTTCAA TAATTAAGATATGAAAGGCTGGGCACGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAAGCCGAGGTG GGTGGATCACGTGAGGTCAGGAGTTAGAGACTAGCCTGGCCAACATGGTGAAACCCCGCCTCTACCAAAA ATACAAAAATTAGGCGGGCTTGGTGGCACACGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGA ATTGCTTGAACCCGGGAGGCAGAGTTTGCAGTAAGCCAAGATCCCAACACTGCACTCCAGCCTGGGTGAT AGAGTGAGACTCGGTCTCAAAAAAAAAAAAAAAATGAAAGATGTTCAAACAATGAGCATTCAAATCTACT CGCAATTCTCACCACACACACACACACAAAAATGATAGTATGTGAGGTAATGCATTCGTTAATCAGATCA ATTTAACCATTCCACAAGGTATATATATTTTAAAAGGTCATGTTTTACATGATAAATACATACCATTTTT ATTTGTCAATTAAAATAAATAAATAAGAAAAATACCACTCACAGAACATAAATTAACAGTGAACATCAAA TCTCTGAAACAGAGATTTCATTCATGTTTACAATATACCCTTGGGATAAACATGCAGCTAAGCCGTTAAA GAAAGTCAGTTCATCAAATGTCAGAAGTTCCCAAAAAGAAATAACTTGTGCATACTTCATTTTTAAAATA TCCCCCATGCATATGTAGAATGCCTTGAAATTAGAGAGGAAGAGGTGAAAGTATGAGGATTTACTTATTA ATAAATAGGTAAGCAGAGAGGGTCAGTCCTTTTCCTTGCAATATCATTCTGTGAAATAAACATTCTGTGA AAGGATGTATATTTTTGTAAGTACCTAGTTCTGTGTATTAGTTGTCTATGCTGCATAGTGAATCACCCCA CAACTTAACAGGTTAAATTCTTTCTCACGGTTTCCAAGGGTCAGGAATCTCACAGTAACTAACCTGGATG GCTCTGGATTAGGATCTCTCATTAGGTTGTGGTCAAGGGGTCATGCAGTGCGGCAGTTATCTGATGGCTT GACTGCAGCTAAGGGTCTACTTCTAAGCCCACTCCCATGGCTCTTTGCAGGAGCCTTCAGTATCCCATCG TGTAGGCCTCTGGTCTACAGGGCTGCCCACAGCATGGTATCTGGATTCCTCCAGAGCGAGTGACCAGGCA GAAAGAGAGAAAAAGCCAAGACTGAGGCCCCAATGTCTTTTATAACCTAACCTCAGAAGTTATATATCAT GATTTCTGCCTCATTCTATTGGTCACACTGACCAATCCTGCTACAGCAGGAGGAGGAGAAGGAGACCACA GGGGGTTGGATGTCAATTGTCTTTCTAACATCTATGATACAAGCAGAGTACTTATAAAAATTCAAATATA TCCTTCTGTCCTGCCCTGCCCACCATTATCTAGAGGGGAAAACTCAGCTGGGATAGGATGTATTTATGGA TGCCTGTTTATATGACATGTGATTTTAAAGGACTGATAAAAAGGCAAATTTAAACAGAGGCCATTTTACT TAAGAAAACCAGTTGCATCTCATTCTTCCTTTTGCAAAGCTTCTGGCAGCTCTTCAGTGTGTAAGCTCAC CCAGGCTCCGCTGGGCGGTTGTCTGGGAGGAGCAGGAAGGGCTTAAAATCCAGTCATTTACAAAGCTGCT AATGATCTTGTTTGTGCACTGTGGTTTGGCCATCATTGCCTTATTTTGAAGAAAGGAAAAAATTATCACA TAATAAACCAATAAAGCAGATATTAAATATTCAGTCAGAACACGTAAACAACTTACTGCTTTGGAATGTA GCTAAAGAAAAACAAATTTATTTGTAAGTATACCCTTCTTTCCTTCAAGGCTGAGAAATCTACAGGAGAA GATAAAGTTTAGCCAATGTTTTCCTGAATTTTAACTGCCTGTGATAGACGTGCTCATATATTCCTCACAT AGCTGTTATTAACTAGCTGTGTGAATTAGGGCATGTTGCTTAGCCTCAGTGAGTCTCATTTTCCTTATCT GTAAAAATGGGGTTCAGGTAACAGGTGCAGGAATCCTCATTTATTTTGTGCCCATGCATACCATGCATTG ACACATACCCATGCTAATCGTCAGAAAACCCTCCAAGTGAGACTAACAGGGTAAACAACTCAGATGACGC AAGTTCCCCTAAGCCATTTAAAGACATTATCCTAAGAGTACTGGGGGGCCACCAAAGTGTTTCAAACAAG CCAGTGATTTCCCTGGGTTTGTATTTAAGATGGATTCTCCTGGTTACATTGTGGTGGGGCCAAAGAATTG TTGAGAGAATACTGTGGTAAACCCAGGCAAGAGCTGATGAGAACTTGAACTAGGGGAGTGACCAAAGGGG AAAAAAAGAGAGAAGTAAACATATTCAAGATATATTTTAAGATATAAGCATACTCAAATATATAGCATGT GGAAATAAGACAATATTTGATAGGAAATATGTGGGAGCCGAGAGCAGACAGGTGAGAGACTGAAAAGAGA AGTGCAATGCCTAGGTCCCTGGCTCAGAGCAGGCAGGGTAAATAGAGGTAAATAGAGGCATCTTCCACTG AGAAAACACAAGAACAGAAGTGGATTTGGAGTAAATGACAAATTCCATTTTAGATACGTTGAATTGTAAA GTATTAGGTTGCCTCCTAAGTGTTAGTTTCATGCAAAAGTAATTATGGTTTGGCCATTATCTCTACCACT CCATCAAAACTACCATTATCCCTACCATGCCCACCACTGATGGGCACCTACATTGATTTTATATCTTTGC TATTGTGAATAGTGCTGCAACGAGCATATGAGTGCATGTGTCTTTTTAGTAAAATGATTTTTTTATAAAT ATACCCAGTATGGGATTGCTGGGTTGAATAGTAGATCTGTTTTAAGTTCTTTGAGAAATCTTCAAACTGC TTTCCACAGTGGCTCAACTAATTTACATTACCAGTGTCTAAGCATTCTTTTTCTCTGCAGCTTCACCAGC ATGTTGTTTTTAGACTTTTTAATTACAGCCATTCTGACTGGTGTGAAATGGCATCTTATTGTGAGATGGT TTTGATTTAAATTTTCCTGATGATTAGTAACGTGGAACTTTATATATATTTGTTGGCCGCTTATATATCA AGACAGGGTTTTGGAACTGAAATGCATATTTGAGGATTATAAGCATACAGAGAATAATTGACACCAGGGA AGGGAATTAATTCTCCCAAGGAAAACGCATTGAGTTACATGAAAAGGGGTCTAGGATTGAACACTGCACT GAGAAACAACAACATCTAGATGATGGATAGGGGAGGAAGAAAGAATTCAGTAAGGAGAATGAAGTTTCTC CTGAAATGAAGGAAGAAAACCAGGATAGTGCCATGCAAAGGAGGTGTTTCAAAGAGGAGGAAGAGATTAA CAGTGCCAAATGCGACTGAGATGTCAAAGAAGTTGAAAGAAATAAGGATATCCTGGGTAGCCTTGGTTAG AGTAGTTCTGGTGGAATGGTAGACATGGAAGTCACATTCTATGGGTTGAGAAGAAAAGGGAGATTAGAAA GGGTAAGGAGTGGATGTTTGAGTGCAGGAAAGACCTAGAAAAGCTACAGAGCATTTTCTAAAAAAGGGGA GCATTTTTTAGAATAAAAGAGATTTGAGCACTCCTTTCATTTACTCATTCATTTGCTCAAGAAATCTTTA CAGGCCAGGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCAGGCGGATCACGAGT TCAAGAGATCGAGACCATCTTGGCTAACACGGTGAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCC GGGCGTGGTGGCGGGCGCCTGTAGTCCCAGCCACTCGGGAGGCTGAGGCAGGAGAATGGCGTGAACCCGG GAGGCGGAGCTTGCAGTGAGCCGAGACTGCGCCACTTCAGTCTGGCCTGGGTGAAAGAGCGAGACTCCGT CTCAAAAAAAAAAAAAAAAAGAGAGAGAGAGAAATCTTTACAGATGGTCTACATAAATGCAGGCACTGTT CTAGAGGCTAAATATGAAACATATTTAAATGCTAATGGAAGGGTCTAGTAAAAAAGGAAAGGTGGAAGAA GGATGTAAGAAAAAAAGAGGAAAGTAAAAGGAGAATCTTGTGAAGGTCAGAAGAGATCTTGAGCATAGGT AGAGGAATTAGCCTTAACGTCAAGAAAAAGGACAATCTCTTATCTGAGCAACAGAAAGAAGACAAAGGCT ATGGGTGCAAATATAAGTAAACGTATAACTAATGAAGCTATTATCTCCATTTTACATATGAAGCCAGTAC TCAAAAAAAAAAAATCAAAGTCCATAATCTTTCCCATTCTCTGGGCTAGATAAAGATTATTAGCAGGAAA ATTACCTAGTGCCCACACAGAGTAGTATAATAGTTTGTTAGGGTGGGCCATGTTGGTAAGGAGTGATCTT ATATTTGCTAGAGGATGCTGTCTTCTTCCACAGGTATGGCGACAATTTCTTTCACAAGCTACTCAATTAA AAACTGGAATAACCTAGCACTACACTTCTATTTATTTCCATTATTTTTCAGCTCACCTTCTAGATTAGTA TACTGGGCACTTCTTGGCTGGACCTCCCGTTAACCTGCTCTTCCTCTATCAGTGGTTCTCAACCCTGCAG CCAAATTACCTGCAGAGTTTTCTAAACGTCTACATGCCATTAGTCCACCCCTAGGGATTCTGATTCTAGA GTCCAGAGGTGAGGCCTAAAAATACATATTTGTAAAAGTTCATGAGTGATGTTGCTGTCCTACCAAAGTT GAGGATCACCATTATACTGCCTTATTAGATGGTTTCTCTAATCCCCCAACTCTAATATTGTTTGTGCTAC TACTCTGGCTACTTTCTAAAAGTGTCATTTTGCTTCTTGTTTTTTTATAGAGGACATAGATGAAAATCTC TTGTTTTGAACGAAGATTTTAAAGAACTCAACTTTCCAGCATCCTCCTCTGTTCTAACCACTTCAGAAAT ATATGCAGCTGTGATACTTGTAGATTTATATTTAGCAAAATGTTAGCATGTATGACAAGACAATGAGAGT AATTGCTTGACAACAACCTATGCACCAGGTATTTAACATTAACTTTGGAAACAAAAATGTACAATTAAGT AAAGTCAACATATGCAAAATACTGTACATTGTGAACAGAAGTTTAATTCATAGTAATTTCACTCTCTGCA TTGACTTATGAGATAATTAATGATTAAACTATTAATGATAAAAATAATGCATTTGTATTGTTCATAATAT CATGTGCACTTCAAGAAAATGGAATGCTACTCTTTTGTGGTTTACGTGTATTATTTTCAATATCTTAATA CCCTAATAAAGAGTCCATAAAAATCCAAATGCTT Download Select all
Length	56174
OMIM ID	606041
HGNC ID	HGNC:11220
Unigene ID	Hs.62886
Ensembl ID	ENSG00000152583
PharmGKB ID	-

mRNA Information

mRNA ID	NM_004684.5
Exon	join(1..459,29919..29983,34377..34523,34906..35922, 37814..37886,38626..38744,39111..39231,46944..47080, 48984..49132,49926..50074,55701..56174)
mRNA Sequence	>8404 AAAAATGCATAAAGAGCCAAGTGCTTATATTCTGGCCAAGTTATGAGGCTCTGAGAACAAGAGC TTGAGGGGAAGACTGTTAACCCCATCCACGCCACCAGAATTAGCTCTTTCCCTTTTGGTTTGCA AGCACTGCCTGTAAAGCCCTCGCATGAGAGGCCAGCCTGCTAGGGAAATCCAGGAATCTGCAAC AAAAACGATGACAGTCTGAAATACTCTCTGGTGCCAACCTCCAAATTCTCGTCTGTCACTTCAG ACCCCCACTAGTTGACAGAGCAGCAGAATTTCAACTCCAGTAGACTTGAATATGCCTCTGGGCA AAGAAGCAGAGCTAACGAGGAAAGGGATTTAAAGAGTTTTTCTTGGGTGTTTGTCAAACTTTTA TTCCCTGTCTGTGTGCAGAGGGGATTCAACTTCAATTTTTCTGCAGTGGCTCTGGGTCCAGCCC CTTACTTAAAGGCCATAAGATGTTTTATTGAAAGAAACTTTCAATATCAAGTAATCCAACCAAC CTTCTAAGATAAGCCTTTTCCTTCAACACAAAGAAGTGCATTTTGCCAAATCTGGAAAGCATGA AGACTGGGCTTTTTTTCCTATGTCTCTTGGGAACTGCAGCTGCAATCCCGACAAATGCAAGATT ATTATCTGATCATTCCAAACCAACTGCTGAAACGGTAGCACCTGACAACACTGCAATCCCCAGT TTAAGGGCTGAAGCTGAAGAAAATGAAAAAGAAACAGCAGTATCCACAGAAGACGATTCCCACC ATAAGGCTGAAAAATCATCAGTACTAAAGTCAAAAGAGGAAAGCCATGAACAGTCAGCAGAACA GGGCAAGAGTTCTAGCCAAGAGCTGGGATTGAAGGATCAAGAGGACAGTGATGGTCACTTAAGT GTGAATTTGGAGTATGCACCAACTGAAGGTACATTGGACATAAAAGAAGATATGAGTGAGCCTC AGGAGAAAAAACTCTCAGAGAACACTGATTTTTTGGCTCCTGGTGTTAGTTCCTTCACAGATTC TAACCAACAAGAAAGTATCACAAAGAGAGAGGAAAACCAAGAACAACCTAGAAATTATTCACAT CATCAGTTGAACAGGAGCAGTAAACATAGCCAAGGCCTAAGGGATCAAGGAAACCAAGAGCAGG ATCCAAATATTTCCAATGGAGAAGAGGAAGAAGAAAAAGAGCCAGGTGAAGTTGGTACCCACAA TGATAACCAAGAAAGAAAGACAGAATTGCCCAGGGAGCATGCTAACAGCAAGCAGGAGGAAGAC AATACCCAATCTGATGATATTTTGGAAGAGTCTGATCAACCAACTCAAGTAAGCAAGATGCAGG AGGATGAATTTGATCAGGGTAACCAAGAACAAGAAGATAACTCCAATGCAGAAATGGAAGAGGA AAATGCATCGAACGTCAATAAGCACATTCAAGAAACTGAATGGCAGAGTCAAGAGGGTAAAACT GGCCTAGAAGCTATCAGCAACCACAAAGAGACAGAAGAAAAGACTGTTTCTGAGGCTCTGCTCA TGGAACCTACTGATGATGGTAATACCACGCCCAGAAATCATGGAGTTGATGATGATGGCGATGA TGATGGCGATGATGGCGGCACTGATGGCCCCAGGCACAGTGCAAGTGATGACTACTTCATCCCA AGCCAGGCCTTTCTGGAGGCCGAGAGAGCTCAATCCATTGCCTATCACCTCAAAATTGAGGAGC AAAGAGAAAAAGTACATGAAAATGAAAATATAGGTACCACTGAGCCTGGAGAGCACCAAGAGGC CAAGAAAGCAGAGAACTCATCAAATGAGGAGGAAACGTCAAGTGAAGGCAACATGAGGGTGCAT GCTGTGGATTCTTGCATGAGCTTCCAGTGTAAAAGAGGCCACATCTGTAAGGCAGACCAACAGG GAAAACCTCACTGTGTCTGCCAGGATCCAGTGACTTGTCCTCCAACAAAACCCCTTGATCAAGT TTGTGGCACTGACAATCAGACCTATGCTAGTTCCTGTCATCTATTCGCTACTAAATGCAGACTG GAGGGGACCAAAAAGGGGCATCAACTCCAGCTGGATTATTTTGGAGCCTGCAAATCTATTCCTA CTTGTACGGACTTTGAAGTGATTCAGTTTCCTCTACGGATGAGAGACTGGCTCAAGAATATCCT CATGCAGCTTTATGAAGCCAACTCTGAACACGCTGGTTATCTAAATGAGAAGCAGAGAAATAAA GTCAAGAAAATTTACCTGGATGAAAAGAGGCTTTTGGCTGGGGACCATCCCATTGATCTTCTCT TAAGGGACTTTAAGAAAAACTACCACATGTATGTGTATCCTGTGCACTGGCAGTTTAGTGAACT TGACCAACACCCTATGGATAGAGTCTTGACACATTCTGAACTTGCTCCTCTGCGAGCATCTCTG GTGCCCATGGAACACTGCATAACCCGTTTCTTTGAGGAGTGTGACCCCAACAAGGATAAGCACA TCACCCTGAAGGAGTGGGGCCACTGCTTTGGAATTAAAGAAGAGGACATAGATGAAAATCTCTT GTTTTGAACGAAGATTTTAAAGAACTCAACTTTCCAGCATCCTCCTCTGTTCTAACCACTTCAG AAATATATGCAGCTGTGATACTTGTAGATTTATATTTAGCAAAATGTTAGCATGTATGACAAGA CAATGAGAGTAATTGCTTGACAACAACCTATGCACCAGGTATTTAACATTAACTTTGGAAACAA AAATGTACAATTAAGTAAAGTCAACATATGCAAAATACTGTACATTGTGAACAGAAGTTTAATT CATAGTAATTTCACTCTCTGCATTGACTTATGAGATAATTAATGATTAAACTATTAATGATAAA AATAATGCATTTGTATTGTTCATAATATCATGTGCACTTCAAGAAAATGGAATGCTACTCTTTT GTGGTTTACGTGTATTATTTTCAATATCTTAATACCCTAATAAAGAGTCCATAAAAATCCAAAT GCTT Download Select all
Length	3012

CDS Information

Location	join(29930..29983,34377..34523,34906..35922,37814..37886, 38626..38744,39111..39231,46944..47080,48984..49132, 49926..50074,55701..55729)
CDS Sequence	>lcl\|NM_001128310.2_cds_NP_001121782.1_1 [gene=SPARCL1] [protein=SPARC-like protein 1 isoform 1 precursor] [protein_id=NP_001121782.1] [location=573..2567] ATGAAGACTGGGCTTTTTTTCCTATGTCTCTTGGGAACTGCAGCTGCAATCCCGACAAATGCAAGATTAT TATCTGATCATTCCAAACCAACTGCTGAAACGGTAGCACCTGACAACACTGCAATCCCCAGTTTAAGGGC TGAAGCTGAAGAAAATGAAAAAGAAACAGCAGTATCCACAGAAGACGATTCCCACCATAAGGCTGAAAAA TCATCAGTACTAAAGTCAAAAGAGGAAAGCCATGAACAGTCAGCAGAACAGGGCAAGAGTTCTAGCCAAG AGCTGGGATTGAAGGATCAAGAGGACAGTGATGGTCACTTAAGTGTGAATTTGGAGTATGCACCAACTGA AGGTACATTGGACATAAAAGAAGATATGAGTGAGCCTCAGGAGAAAAAACTCTCAGAGAACACTGATTTT TTGGCTCCTGGTGTTAGTTCCTTCACAGATTCTAACCAACAAGAAAGTATCACAAAGAGAGAGGAAAACC AAGAACAACCTAGAAATTATTCACATCATCAGTTGAACAGGAGCAGTAAACATAGCCAAGGCCTAAGGGA TCAAGGAAACCAAGAGCAGGATCCAAATATTTCCAATGGAGAAGAGGAAGAAGAAAAAGAGCCAGGTGAA GTTGGTACCCACAATGATAACCAAGAAAGAAAGACAGAATTGCCCAGGGAGCATGCTAACAGCAAGCAGG AGGAAGACAATACCCAATCTGATGATATTTTGGAAGAGTCTGATCAACCAACTCAAGTAAGCAAGATGCA GGAGGATGAATTTGATCAGGGTAACCAAGAACAAGAAGATAACTCCAATGCAGAAATGGAAGAGGAAAAT GCATCGAACGTCAATAAGCACATTCAAGAAACTGAATGGCAGAGTCAAGAGGGTAAAACTGGCCTAGAAG CTATCAGCAACCACAAAGAGACAGAAGAAAAGACTGTTTCTGAGGCTCTGCTCATGGAACCTACTGATGA TGGTAATACCACGCCCAGAAATCATGGAGTTGATGATGATGGCGATGATGATGGCGATGATGGCGGCACT GATGGCCCCAGGCACAGTGCAAGTGATGACTACTTCATCCCAAGCCAGGCCTTTCTGGAGGCCGAGAGAG CTCAATCCATTGCCTATCACCTCAAAATTGAGGAGCAAAGAGAAAAAGTACATGAAAATGAAAATATAGG TACCACTGAGCCTGGAGAGCACCAAGAGGCCAAGAAAGCAGAGAACTCATCAAATGAGGAGGAAACGTCA AGTGAAGGCAACATGAGGGTGCATGCTGTGGATTCTTGCATGAGCTTCCAGTGTAAAAGAGGCCACATCT GTAAGGCAGACCAACAGGGAAAACCTCACTGTGTCTGCCAGGATCCAGTGACTTGTCCTCCAACAAAACC CCTTGATCAAGTTTGTGGCACTGACAATCAGACCTATGCTAGTTCCTGTCATCTATTCGCTACTAAATGC AGACTGGAGGGGACCAAAAAGGGGCATCAACTCCAGCTGGATTATTTTGGAGCCTGCAAATCTATTCCTA CTTGTACGGACTTTGAAGTGATTCAGTTTCCTCTACGGATGAGAGACTGGCTCAAGAATATCCTCATGCA GCTTTATGAAGCCAACTCTGAACACGCTGGTTATCTAAATGAGAAGCAGAGAAATAAAGTCAAGAAAATT TACCTGGATGAAAAGAGGCTTTTGGCTGGGGACCATCCCATTGATCTTCTCTTAAGGGACTTTAAGAAAA ACTACCACATGTATGTGTATCCTGTGCACTGGCAGTTTAGTGAACTTGACCAACACCCTATGGATAGAGT CTTGACACATTCTGAACTTGCTCCTCTGCGAGCATCTCTGGTGCCCATGGAACACTGCATAACCCGTTTC TTTGAGGAGTGTGACCCCAACAAGGATAAGCACATCACCCTGAAGGAGTGGGGCCACTGCTTTGGAATTA AAGAAGAGGACATAGATGAAAATCTCTTGTTTTGA Download Select all
CCDS ID	CCDS3622.1

Protein Information

Protein ID	NP_001121782.1
Protein Name	SPARC-like 1 (hevin)
Molecular Wt. (Da)	73569
Protein Sequence	>8404 MKTGLFFLCLLGTAAAIPTNARLLSDHSKPTAETVAPDNTAIPSLRAEAEENEKETAVSTEDDS HHKAEKSSVLKSKEESHEQSAEQGKSSSQELGLKDQEDSDGHLSVNLEYAPTEGTLDIKEDMSE PQEKKLSENTDFLAPGVSSFTDSNQQESITKREENQEQPRNYSHHQLNRSSKHSQGLRDQGNQE QDPNISNGEEEEEKEPGEVGTHNDNQERKTELPREHANSKQEEDNTQSDDILEESDQPTQVSKM QEDEFDQGNQEQEDNSNAEMEEENASNVNKHIQETEWQSQEGKTGLEAISNHKETEEKTVSEAL LMEPTDDGNTTPRNHGVDDDGDDDGDDGGTDGPRHSASDDYFIPSQAFLEAERAQSIAYHLKIE EQREKVHENENIGTTEPGEHQEAKKAENSSNEEETSSEGNMRVHAVDSCMSFQCKRGHICKADQ QGKPHCVCQDPVTCPPTKPLDQVCGTDNQTYASSCHLFATKCRLEGTKKGHQLQLDYFGACKSI PTCTDFEVIQFPLRMRDWLKNILMQLYEANSEHAGYLNEKQRNKVKKIYLDEKRLLAGDHPIDL LLRDFKKNYHMYVYPVHWQFSELDQHPMDRVLTHSELAPLRASLVPMEHCITRFFEECDPNKDK HITLKEWGHCFGIKEEDIDENLLF Download Select all
Length	664
Uniprot ID	P40933
Ensembl Protein ID	ENSP00000296545

Post-translational Modification Information (Source : HPRD)

Residue	Type	site
S	Phosphorylation	295
S	Phosphorylation	84
S	Phosphorylation	91
S	Phosphorylation	92
S	Phosphorylation	198
S	Phosphorylation	272

Enzyme Information

No matching records could be found.

PPi Information

(Click to view network : Source STRING) View

Interactant Gene ID (Source: HPRD)	Gene Symbol	HPRD ID	Ref Seq ID	Technique	References
5621	PRNP	1453	NP_000302.1	in vivo	15146195

Pathway Information

No matching records could be found.

Structure Information

No matching records could be found.

Domain Information

ID	Location	Description
cd00252	514-662	SPARC_EC
cl22905	514-662	SPARC_EC superfamily
pfam10591	513-650	SPARC_Ca_bdg
cd01328	433-512	FSL_SPARC
cl00097	433-512	KAZAL_FS superfamily
pfam00050	456-509	Kazal_1
smart00280	455-509	KAZAL
pfam07648	465-509	Kazal_2
cd00104	462-509	KAZAL_FS
pfam09289	433-454	FOLN
cl23022	433-454	FOLN superfamily
smart00274	432-455	FOLN
cl23052	432-455	FOLN superfamily
cd01327	462-485	KAZAL_PSTI
pfam07423	232-299	DUF1510
cl22487	232-299	DUF1510 superfamily
COG5271	23-400	MDN1
PRK08581	1-297	PRK08581

Ontology Information

HPRD ID	4396
Molecular Class	Secreted polypeptide
Molecular Function	Cytokine activity (GO:0005125)
Biological Process	Immune response (GO:0006955)

SNP Information

View SNP Geneview Report

Drug Information

No matching records could be found.

External Links

ArrayExpress GO
ICGC GO
Cancer3D GO
COSMIC GO
NCG GO
TSGene GO
Tumor Gene Family of Databases GO
CCDB GO
G2SBC GO
Osteosarcoma Database GO
RCDB GO

ArrayExpress	GO
ICGC	GO
Cancer3D	GO
COSMIC	GO
NCG	GO
TSGene	GO
Tumor Gene Family of Databases	GO
CCDB	GO
G2SBC	GO
Osteosarcoma Database	GO
RCDB	GO

CoReCG

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General Information

Evidence Information

Gene Details

mRNA Information

CDS Information

Protein Information

Post-translational Modification Information (Source : HPRD)

Enzyme Information

PPi Information

Pathway Information

Structure Information

Domain Information

Ontology Information

SNP Information

Drug Information

External Links

Important Information