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Pathway Name: p53 signaling pathway

Pathway Information (Click on respective Gene ID or Gene Symbol for more information)


Pathway ID Gene ID Gene Symbol Gene Name
hsa04115 1017 CDK2 Cyclin-dependent kinase 2
hsa04115 1019 CDK4 cyclin-dependent kinase 4
hsa04115 1021 CDK6 Cyclin-dependent kinase 6
hsa04115 1026 CDKN1A Cyclin-dependent kinase inhibitor 1A (p21, Cip1)
hsa04115 1029 CDKN2A cyclin-dependent kinase inhibitor 2A
hsa04115 1111 CHEK1 checkpoint kinase 1
hsa04115 11200 CHEK2 checkpoint kinase 2
hsa04115 1643 DDB2 damage-specific DNA binding protein 2, 48kDa
hsa04115 1647 GADD45A growth arrest and DNA-damage-inducible, alpha
hsa04115 317 APAF1 Apoptotic peptidase activating factor 1
hsa04115 3479 IGF1 Insulin-like growth factor 1 (somatomedin C)
hsa04115 3486 IGFBP3 insulin-like growth factor binding protein 3
hsa04115 355 FAS Fas (TNF receptor superfamily, member 6)
hsa04115 3732 CD82 CD82 molecule
hsa04115 4193 MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
hsa04115 4194 MDM4 MDM4, p53 regulator
hsa04115 4616 GADD45B growth arrest and DNA-damage-inducible, beta
hsa04115 472 ATM Ataxia telangiectasia mutated
hsa04115 50484 RRM2B Ribonucleotide reductase M2 B (TP53 inducible)
hsa04115 5054 SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
hsa04115 5268 SERPINB5 Serpin peptidase inhibitor, clade B (ovalbumin), member 5
hsa04115 545 ATR ATR serine/threonine kinase
hsa04115 5728 PTEN Phosphatase and tensin homolog (mutated in multiple advanced cancers 1)
hsa04115 575 BAI1 brain-specific angiogenesis inhibitor 1
hsa04115 581 BAX BCL2-associated X protein
hsa04115 595 CCND1 Cyclin D1
hsa04115 6241 RRM2 Ribonucleotide reductase M2 polypeptide
hsa04115 7057 THBS1 thrombospondin 1
hsa04115 7157 TP53 tumor protein p53
hsa04115 7161 TP73 tumor protein p73
hsa04115 7249 TSC2 tuberous sclerosis 2
hsa04115 836 CASP3 caspase 3, apoptosis-related cysteine peptidase
hsa04115 841 CASP8 caspase 8, apoptosis-related cysteine peptidase
hsa04115 842 CASP9 caspase 9, apoptosis-related cysteine peptidase
hsa04115 8493 PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D
hsa04115 891 CCNB1 cyclin B1
hsa04115 894 CCND2 cyclin D2
hsa04115 896 CCND3 cyclin D3
hsa04115 898 CCNE1 cyclin E1
hsa04115 900 CCNG1 cyclin G1
hsa04115 901 CCNG2 cyclin G2
hsa04115 9133 CCNB2 cyclin B2
hsa04115 9134 CCNE2 cyclin E2
hsa04115 983 CDK1 cyclin-dependent kinase 1