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Pathway Name: Natural killer cell mediated cytotoxicity

Pathway Information (Click on respective Gene ID or Gene Symbol for more information)


Pathway ID Gene ID Gene Symbol Gene Name
hsa04650 100507436 MICA MHC class I polypeptide-related sequence A
hsa04650 10451 VAV3 vav 3 guanine nucleotide exchange factor
hsa04650 1437 CSF2 colony stimulating factor 2 (granulocyte-macrophage)
hsa04650 154064 RAET1L Retinoic acid early transcript 1L
hsa04650 23533 PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
hsa04650 2885 GRB2 Growth factor receptor-bound protein 2
hsa04650 3002 GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
hsa04650 3105 HLA-A major histocompatibility complex, class I, A
hsa04650 3107 HLA-C major histocompatibility complex, class I, C
hsa04650 3133 HLA-E major histocompatibility complex, class I, E
hsa04650 3135 HLA-G HLA-G histocompatibility antigen, class I, G
hsa04650 3265 HRAS Harvey rat sarcoma viral oncogene homolog
hsa04650 3383 ICAM1 Intercellular adhesion molecule 1 (CD54), human rhinovirus receptor
hsa04650 3439 IFNA1 Interferon, alpha 1
hsa04650 3454 IFNAR1 interferon (alpha, beta and omega) receptor 1
hsa04650 3458 IFNG Interferon, gamma
hsa04650 355 FAS Fas (TNF receptor superfamily, member 6)
hsa04650 356 FASLG Fas ligand (TNF superfamily, member 6)
hsa04650 3689 ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
hsa04650 369 ARAF A-Raf proto-oncogene, serine/threonine kinase
hsa04650 3810 KIR2DS5 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 5
hsa04650 3845 KRAS V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
hsa04650 3932 LCK LCK proto-oncogene, Src family tyrosine kinase
hsa04650 4773 NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
hsa04650 4893 NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
hsa04650 5058 PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
hsa04650 5290 PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
hsa04650 5291 PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
hsa04650 5293 PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
hsa04650 5294 PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
hsa04650 5295 PIK3R1 Phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha)
hsa04650 5296 PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
hsa04650 5530 PPP3CA Protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform
hsa04650 5578 PRKCA Protein kinase C, alpha
hsa04650 5594 MAPK1 mitogen-activated protein kinase 1
hsa04650 5595 MAPK3 mitogen-activated protein kinase 3
hsa04650 5604 MAP2K1 mitogen-activated protein kinase kinase 1
hsa04650 5781 PTPN11 protein tyrosine phosphatase, non-receptor type 11
hsa04650 5879 RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
hsa04650 5894 RAF1 V-raf-1 murine leukemia viral oncogene homolog 1
hsa04650 6464 SHC1 SHC (Src homology 2 domain containing) transforming protein 1
hsa04650 6654 SOS1 son of sevenless homolog 1 (Drosophila)
hsa04650 673 BRAF B-Raf proto-oncogene, serine/threonine kinase
hsa04650 6850 SYK spleen tyrosine kinase
hsa04650 7124 TNF Tumor necrosis factor (TNF superfamily, member 2)
hsa04650 7409 VAV1 vav 1 guanine nucleotide exchange factor
hsa04650 7535 ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
hsa04650 836 CASP3 caspase 3, apoptosis-related cysteine peptidase
hsa04650 8503 PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)