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Pathway Name: HIF-1 signaling pathway

Pathway Information (Click on respective Gene ID or Gene Symbol for more information)


Pathway ID Gene ID Gene Symbol Gene Name
hsa04066 10000 AKT3 v-akt murine thymoma viral oncogene homolog 3
hsa04066 1026 CDKN1A Cyclin-dependent kinase inhibitor 1A (p21, Cip1)
hsa04066 1027 CDKN1B Cyclin-dependent kinase inhibitor 1B (p27, Kip1)
hsa04066 112399 EGLN3 Egl nine homolog 3 (C. elegans)
hsa04066 1950 EGF epidermal growth factor
hsa04066 1956 EGFR Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
hsa04066 1978 EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
hsa04066 2023 ENO1 enolase 1, (alpha)
hsa04066 2033 EP300 E1A binding protein p300
hsa04066 2056 EPO erythropoietin
hsa04066 2064 ERBB2 V-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
hsa04066 207 AKT1 v-akt murine thymoma viral oncogene homolog 1
hsa04066 208 AKT2 V-akt murine thymoma viral oncogene homolog 2
hsa04066 226 ALDOA Aldolase A, fructose-bisphosphate
hsa04066 2321 FLT1 fms-related tyrosine kinase 1
hsa04066 23533 PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
hsa04066 2475 MTOR mechanistic target of rapamycin (serine/threonine kinase)
hsa04066 2597 GAPDH Glyceraldehyde-3-phosphate dehydrogenase
hsa04066 27035 NOX1 NADPH oxidase 1
hsa04066 284 ANGPT1 angiopoietin 1
hsa04066 285 ANGPT2 angiopoietin 2
hsa04066 3091 HIF1A Hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
hsa04066 3098 HK1 hexokinase 1
hsa04066 3099 HK2 hexokinase 2
hsa04066 3458 IFNG Interferon, gamma
hsa04066 3479 IGF1 Insulin-like growth factor 1 (somatomedin C)
hsa04066 3480 IGF1R Insulin-like growth factor 1 receptor
hsa04066 3569 IL6 interleukin 6
hsa04066 3643 INSR insulin receptor
hsa04066 3939 LDHA lactate dehydrogenase A
hsa04066 405 ARNT aryl hydrocarbon receptor nuclear translocator
hsa04066 4055 LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
hsa04066 4790 NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
hsa04066 4843 NOS2A Nitric oxide synthase 2A (inducible, hepatocytes)
hsa04066 4846 NOS3 Nitric oxide synthase 3 (endothelial cell)
hsa04066 5054 SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
hsa04066 5163 PDK1 pyruvate dehydrogenase kinase, isozyme 1
hsa04066 5230 PGK1 phosphoglycerate kinase 1
hsa04066 5290 PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
hsa04066 5291 PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
hsa04066 5293 PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
hsa04066 5294 PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
hsa04066 5295 PIK3R1 Phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha)
hsa04066 5296 PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
hsa04066 5578 PRKCA Protein kinase C, alpha
hsa04066 5594 MAPK1 mitogen-activated protein kinase 1
hsa04066 5595 MAPK3 mitogen-activated protein kinase 3
hsa04066 5604 MAP2K1 mitogen-activated protein kinase kinase 1
hsa04066 596 BCL2 B-cell CLL/lymphoma 2
hsa04066 5970 RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
hsa04066 6198 RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
hsa04066 6199 RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
hsa04066 6513 SLC2A1 Solute carrier family 2 (facilitated glucose transporter), member 1
hsa04066 6774 STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
hsa04066 7037 TFRC Transferrin receptor (p90, CD71)
hsa04066 7076 TIMP1 TIMP metallopeptidase inhibitor 1
hsa04066 7099 TLR4 Toll-like receptor 4
hsa04066 7422 VEGFA Vascular endothelial growth factor A
hsa04066 7428 VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
hsa04066 815 CAMK2A Calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha
hsa04066 8503 PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)