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Pathway Name: FoxO signaling pathway

Pathway Information (Click on respective Gene ID or Gene Symbol for more information)


Pathway ID Gene ID Gene Symbol Gene Name
hsa04068 10000 AKT3 v-akt murine thymoma viral oncogene homolog 3
hsa04068 10018 BCL2L11 BCL2-like 11 (apoptosis facilitator)
hsa04068 1017 CDK2 Cyclin-dependent kinase 2
hsa04068 1026 CDKN1A Cyclin-dependent kinase inhibitor 1A (p21, Cip1)
hsa04068 1027 CDKN1B Cyclin-dependent kinase inhibitor 1B (p27, Kip1)
hsa04068 1030 CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
hsa04068 11337 GABARAP GABA(A) receptor-associated protein
hsa04068 1432 MAPK14 mitogen-activated protein kinase 14
hsa04068 1647 GADD45A growth arrest and DNA-damage-inducible, alpha
hsa04068 1950 EGF epidermal growth factor
hsa04068 1956 EGFR Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
hsa04068 2033 EP300 E1A binding protein p300
hsa04068 207 AKT1 v-akt murine thymoma viral oncogene homolog 1
hsa04068 208 AKT2 V-akt murine thymoma viral oncogene homolog 2
hsa04068 2308 FOXO1 forkhead box O1
hsa04068 2309 FOXO3 Forkhead box O3
hsa04068 23411 SIRT1 sirtuin 1
hsa04068 23533 PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
hsa04068 2885 GRB2 Growth factor receptor-bound protein 2
hsa04068 3265 HRAS Harvey rat sarcoma viral oncogene homolog
hsa04068 3479 IGF1 Insulin-like growth factor 1 (somatomedin C)
hsa04068 3480 IGF1R Insulin-like growth factor 1 receptor
hsa04068 3551 IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
hsa04068 356 FASLG Fas ligand (TNF superfamily, member 6)
hsa04068 3569 IL6 interleukin 6
hsa04068 3586 IL10 Interleukin 10
hsa04068 3643 INSR insulin receptor
hsa04068 3667 IRS1 insulin receptor substrate 1
hsa04068 369 ARAF A-Raf proto-oncogene, serine/threonine kinase
hsa04068 3845 KRAS V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
hsa04068 4087 SMAD2 SMAD family member 2
hsa04068 4088 SMAD3 SMAD family member 3
hsa04068 4089 SMAD4 SMAD family member 4
hsa04068 4193 MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
hsa04068 4303 FOXO4 forkhead box O4
hsa04068 4616 GADD45B growth arrest and DNA-damage-inducible, beta
hsa04068 472 ATM Ataxia telangiectasia mutated
hsa04068 4893 NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
hsa04068 51422 PRKAG2 Protein kinase, AMP-activated, gamma 2 non-catalytic subunit
hsa04068 5170 PDPK1 3-phosphoinositide dependent protein kinase-1
hsa04068 51701 NLK nemo-like kinase
hsa04068 5290 PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
hsa04068 5291 PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
hsa04068 5293 PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
hsa04068 5294 PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
hsa04068 5295 PIK3R1 Phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha)
hsa04068 5296 PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
hsa04068 5347 PLK1 polo-like kinase 1
hsa04068 5562 PRKAA1 Protein kinase, AMP-activated, alpha 1 catalytic subunit
hsa04068 5563 PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
hsa04068 5594 MAPK1 mitogen-activated protein kinase 1
hsa04068 5595 MAPK3 mitogen-activated protein kinase 3
hsa04068 5599 MAPK8 mitogen-activated protein kinase 8
hsa04068 5600 MAPK11 mitogen-activated protein kinase 11
hsa04068 5601 MAPK9 mitogen-activated protein kinase 9
hsa04068 5604 MAP2K1 mitogen-activated protein kinase kinase 1
hsa04068 5728 PTEN Phosphatase and tensin homolog (mutated in multiple advanced cancers 1)
hsa04068 5894 RAF1 V-raf-1 murine leukemia viral oncogene homolog 1
hsa04068 595 CCND1 Cyclin D1
hsa04068 604 BCL6 B-cell CLL/lymphoma 6
hsa04068 6446 SGK1 serum/glucocorticoid regulated kinase 1
hsa04068 6502 SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
hsa04068 664 BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
hsa04068 6648 SOD2 Superoxide dismutase 2, mitochondrial
hsa04068 6654 SOS1 son of sevenless homolog 1 (Drosophila)
hsa04068 673 BRAF B-Raf proto-oncogene, serine/threonine kinase
hsa04068 6774 STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
hsa04068 6794 STK11 Serine/threonine kinase 11
hsa04068 7040 TGFB1 transforming growth factor, beta 1
hsa04068 7042 TGFB2 transforming growth factor, beta 2
hsa04068 7043 TGFB3 transforming growth factor, beta 3
hsa04068 7046 TGFBR1 transforming growth factor, beta receptor 1
hsa04068 7048 TGFBR2 Transforming growth factor, beta receptor II (70/80kDa)
hsa04068 7874 USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
hsa04068 847 CAT Catalase
hsa04068 8503 PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
hsa04068 8660 IRS2 insulin receptor substrate 2
hsa04068 891 CCNB1 cyclin B1
hsa04068 894 CCND2 cyclin D2
hsa04068 901 CCNG2 cyclin G2
hsa04068 9133 CCNB2 cyclin B2
hsa04068 9140 ATG12 autophagy related 12
hsa04068 9455 HOMER2 homer scaffolding protein 2